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gentamicin and Hematologic Malignancies

gentamicin has been researched along with Hematologic Malignancies in 8 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
"The pharmacokinetics (PK) of isepamicin were studied in 8 febrile neutropenic patients with hematologic malignancy and in 20 young women with acute pelvic inflammatory disease (PID)."9.11Key pharmacokinetic parameters of isepamicin in febrile neutropenic cancer patients and in women with acute pelvic inflammatory disease. ( Gala, JL; Leal, T; Vandercam, B; Wallemacq, P; Yombi, JC, 2005)
"During a 12-month study, 42 adult patients with febrile neutropenia (granulocytes < 1 x 10(9)/l) were treated with once-daily gentamicin (5 mg/kg)."7.69Audit of once-daily dosing gentamicin therapy in neutropenic fever. ( Cooke, RP; Gover, PA; Grace, RJ, 1997)
"The pharmacokinetics (PK) of isepamicin were studied in 8 febrile neutropenic patients with hematologic malignancy and in 20 young women with acute pelvic inflammatory disease (PID)."5.11Key pharmacokinetic parameters of isepamicin in febrile neutropenic cancer patients and in women with acute pelvic inflammatory disease. ( Gala, JL; Leal, T; Vandercam, B; Wallemacq, P; Yombi, JC, 2005)
" If fever persisted, teicoplanin plus gentamicin (group A) or teicoplanin plus ciprofloxacin (group B) were added."5.10Piperacillin-tazobactam is more effective than ceftriaxone plus gentamicin in febrile neutropenic patients with hematological malignancies: a randomized comparison. ( Fixson, A; Glasmacher, A; Gorschlüter, M; Hahn, C; Horré, R; Marklein, G; Mey, U; Molitor, E; Sauerbruch, T; Schmidt-Wolf, IG; Ziske, C, 2003)
"During a 12-month study, 42 adult patients with febrile neutropenia (granulocytes < 1 x 10(9)/l) were treated with once-daily gentamicin (5 mg/kg)."3.69Audit of once-daily dosing gentamicin therapy in neutropenic fever. ( Cooke, RP; Gover, PA; Grace, RJ, 1997)
" We conclude that neutropenic patients form a target group for successful pharmacokinetic intervention and cost saving."1.30Clinical outcome and economic impact of aminoglycoside peak concentrations in febrile immunocompromised patients with hematologic malignancies. ( Armstrong, VW; Binder, C; Binder, L; Erichsen, N; Hiddemann, W; Menke, CF; Oellerich, M; Schiel, X; Schüttrumpf, S; Unterhalt, M, 1998)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's5 (62.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vinker-Shuster, M1
Stepensky, P1
Temper, V1
Shayovitz, V1
Masarwa, R1
Averbuch, D2
Makhoul, R1
Rotshild, V1
Weintraub, M1
Engelhard, D1
Amaya, RA1
Edwards, MS1
Gorschlüter, M1
Hahn, C1
Fixson, A1
Mey, U1
Ziske, C1
Molitor, E1
Horré, R1
Sauerbruch, T1
Marklein, G1
Schmidt-Wolf, IG1
Glasmacher, A1
Yombi, JC1
Wallemacq, P1
Leal, T1
Gala, JL1
Vandercam, B1
Ritchie, S1
Palmer, S1
Ellis-Pegler, R1
Cooke, RP1
Grace, RJ1
Gover, PA1
Binder, L1
Schiel, X1
Binder, C1
Menke, CF1
Schüttrumpf, S1
Armstrong, VW1
Unterhalt, M1
Erichsen, N1
Hiddemann, W1
Oellerich, M1

Reviews

1 review available for gentamicin and Hematologic Malignancies

ArticleYear
Agrobacterium radiobacter bacteremia in pediatric patients: case report and review.
    The Pediatric infectious disease journal, 2003, Volume: 22, Issue:2

    Topics: Bacteremia; Catheterization, Central Venous; Child; Device Removal; Drug Therapy, Combination; Femal

2003

Trials

3 trials available for gentamicin and Hematologic Malignancies

ArticleYear
Gram-negative Bacteremia in Children With Hematologic Malignancies and Following Hematopoietic Stem Cell Transplantation: Epidemiology, Resistance, and Outcome.
    Journal of pediatric hematology/oncology, 2019, Volume: 41, Issue:8

    Topics: Adolescent; Allografts; Bacteremia; Child; Child, Preschool; Drug Combinations; Drug Resistance, Bac

2019
Piperacillin-tazobactam is more effective than ceftriaxone plus gentamicin in febrile neutropenic patients with hematological malignancies: a randomized comparison.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2003, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ceftriaxone; Cost-Benefit Analysi

2003
Key pharmacokinetic parameters of isepamicin in febrile neutropenic cancer patients and in women with acute pelvic inflammatory disease.
    Journal of chemotherapy (Florence, Italy), 2005, Volume: 17, Issue:5

    Topics: Acute Disease; Adult; Anti-Bacterial Agents; Area Under Curve; Female; Fever; Gentamicins; Hematolog

2005

Other Studies

4 other studies available for gentamicin and Hematologic Malignancies

ArticleYear
Empiric treatment with once-daily cefonicid and gentamicin for febrile non-neutropenic pediatric cancer patients with indwelling central venous catheters.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:7

    Topics: Adolescent; Anti-Bacterial Agents; Bacteremia; Catheterization, Central Venous; Catheters, Indwellin

2008
High-risk febrile neutropenia in Auckland 2003-2004: the influence of the microbiology laboratory on patient treatment and the use of pathogen-specific therapy.
    Internal medicine journal, 2007, Volume: 37, Issue:1

    Topics: Anti-Bacterial Agents; Bacteremia; Bacteria; Bacterial Infections; Catheterization; Cefepime; Cephal

2007
Audit of once-daily dosing gentamicin therapy in neutropenic fever.
    International journal of clinical practice, 1997, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bone Marrow Diseases; Drug Admini

1997
Clinical outcome and economic impact of aminoglycoside peak concentrations in febrile immunocompromised patients with hematologic malignancies.
    Clinical chemistry, 1998, Volume: 44, Issue:2

    Topics: Adult; Aged; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Infections; Cephalosporins; Dru

1998