gentamicin and Hearing Loss, Sensorineural
gentamicin has been researched along with Hearing Loss, Sensorineural in 94 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Hearing Loss, Sensorineural: Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Intra tympanic gentamicin is more effective in controlling tinnitus as compared to dexamethasone and placebo and there was no marked difference in control of tinnitus between placebo and steroids." | 9.24 | Short Term Results of Intra Tympanic Gentamicin and Dexamethasone on Hearing and Tinnitus in Meniere's disease: A Case Control Study. ( Shamas, IU, 2017) |
"In the gentamicin group, vertigo symptoms were controlled in 22 patients (92%), deterioration in hearing was seen in only two patients (8%)." | 9.12 | [Intratympanic treatment in Meniere's disease: the effect of gentamicin and dexamethasone on vertigo control and hearing]. ( Akkuzu, B; Ozgirgin, N; Ozlüoğlu, LN, 2006) |
"In the treatment of serious infection by aminoglycoside antibiotics multiple daily treatment with netilmicin is considered to be the least toxic." | 9.08 | Ototoxicity and nephrotoxicity of gentamicin vs netilmicin in patients with serious infections. A randomized clinical trial. ( Büller, HR; Dreschler, WA; Kuijper, EJ; Prins, JM; Speelman, P; Tange, RA, 1995) |
"Of these, 68 patients had Meniere's disease; 4 patients had recurrent vertigo after endolymphatic sac surgery and were followed for at least 1 year." | 5.31 | Intratympanic gentamicin therapy for persistent vertigo after endolymphatic sac surgery. ( Leonetti, JP; Marzo, SJ, 2002) |
"Intra tympanic gentamicin is more effective in controlling tinnitus as compared to dexamethasone and placebo and there was no marked difference in control of tinnitus between placebo and steroids." | 5.24 | Short Term Results of Intra Tympanic Gentamicin and Dexamethasone on Hearing and Tinnitus in Meniere's disease: A Case Control Study. ( Shamas, IU, 2017) |
"In the gentamicin group, vertigo symptoms were controlled in 22 patients (92%), deterioration in hearing was seen in only two patients (8%)." | 5.12 | [Intratympanic treatment in Meniere's disease: the effect of gentamicin and dexamethasone on vertigo control and hearing]. ( Akkuzu, B; Ozgirgin, N; Ozlüoğlu, LN, 2006) |
"In the treatment of serious infection by aminoglycoside antibiotics multiple daily treatment with netilmicin is considered to be the least toxic." | 5.08 | Ototoxicity and nephrotoxicity of gentamicin vs netilmicin in patients with serious infections. A randomized clinical trial. ( Büller, HR; Dreschler, WA; Kuijper, EJ; Prins, JM; Speelman, P; Tange, RA, 1995) |
"Ototoxic drugs given to sick infants with "fever", without weight recording or gentamicin level monitoring, was the probable cause of a third of all severe/profound deafened Zanzibarian children." | 3.76 | Sensorineural deafness in Tanzanian children--is ototoxicity a significant cause? A pilot study. ( Freeland, A; Jones, J; Mohammed, NK, 2010) |
"Intratympanic gentamicin perfusion provides effective control of vertigo in patients with Ménière's disease." | 3.75 | Hearing results following intratympanic gentamicin perfusion for Ménière's disease. ( Aidonis, I; Kyrodimos, E; Sismanis, A, 2009) |
"To describe the histopathology and morphometry of the vestibular end organs from a 59-year-old Meniere's patient who underwent transmastoid labyrinthectomy for recurrent vertigo after failed intratympanic gentamicin." | 3.74 | Histopathology of the vestibular end organs after intratympanic gentamicin failure for Meniere's disease. ( Baloh, RW; Ishiyama, A; Ishiyama, G; Lopez, I, 2007) |
"Intratympanic gentamicin treatment ought to be offered to Ménière's patients suffering from disabling vertigo, with the proviso that they be made aware of the possibility of hearing deterioration." | 3.73 | Intratympanic gentamicin treatment in Meniere's disease: patients' experiences and outcomes. ( Prinsley, PR; Sandooram, D; Smith, WK, 2006) |
"The study was a longitudinal analysis of hearing and control of vertigo in patients with unilateral Ménière's disease who received intratympanic gentamicin." | 3.72 | Long-term hearing outcome in patients receiving intratympanic gentamicin for Ménière's disease. ( Minor, LB; Wu, IC, 2003) |
" There was no difference in general quality of life, present hearing loss, or tinnitus between the three treatment groups, but the gentamicin-treated patients had less vertigo than did the other groups." | 3.71 | Patients' subjective evaluations of quality of life related to disease-specific symptoms, sense of coherence, and treatment in Ménière's disease. ( Bagger-Sjöbäck, D; Bergenius, J; Langius, A; Söderman, AC; Tjell, C, 2001) |
"The role of mitochondrial biogenesis in hair cell survival after injury was evaluated by inhibiting mitochondrial protein synthesis with chloramphenicol and then studying the effects on hair cell survival after exposure to two different types of ototoxins, gentamicin and acoustic trauma." | 3.69 | Mitochondrial role in hair cell survival after injury. ( Hyde, GE; Rubel, EW, 1995) |
" Dosage or duration of aminoglycosides use did not relate to SNHL." | 2.72 | Ototoxic drugs and sensorineural hearing loss following severe neonatal respiratory failure. ( Cheung, PY; Etches, PC; Peliowski, A; Robertson, CM; Tyebkhan, JM, 2006) |
"No substantial sensorineural hearing loss or vestibular dysfunction was identified in these patients that could be attributed to aminoglycoside therapy." | 2.65 | Ototoxicity in neonates treated with gentamicin and kanamycin: results of a four-year controlled follow-up study. ( Allen, DA; Chrane, DF; Finitzo-Hieber, T; McCracken, GH; Morrow, J; Roeser, RJ, 1979) |
"Gentamicin is an antibiotic member of the aminoglycosides family with well known potential to cause permanent ototoxicity by damaging more likely the cochlea vestibular system." | 2.42 | [Cochlear-vestibular ototoxicity by gentamicin. Report of a case and literature review]. ( Blasco Huelva, A; González Palomino, A; Keituqwa Yáñez, T; Marcos García, M; Pardo Romero, G; Pino Rivero, V; Trinidad Ruiz, G, 2004) |
"Medical management of Meniere's disease is successful in approximately 70% of patients." | 2.40 | Role of chemical labyrinthectomy in the treatment of Meniere's disease. ( Hirsch, BE; Kamerer, DB, 1997) |
"Gentamicin was utilized to establish the SNHL model in rats, followed by the treatments of antagomir-106a and antagomir-106a combined with carbenoxolone, an inhibitor of connexin-43." | 1.72 | MiR-106a facilitates the sensorineural hearing loss induced by oxidative stress by targeting connexin-43. ( Ding, L; Wang, J, 2022) |
"Frequent causes of sensorineural hearing loss are due to damage or loss of the sensory hair cells, the spiral ganglion neurons, or the synapses between them." | 1.62 | A deep learning approach to quantify auditory hair cells. ( Bodmer, D; Cortada, M; Lanz, M; Levano, S; Sauteur, L, 2021) |
"However, moderate to flat sensorineural hearing loss was also observed." | 1.46 | Intralabyrinthine Vestibular Schwannoma Responsive to Intratympanic Gentamicin Treatment. ( Barbara, M; Covelli, E; Filippi, C; Marrone, V; Monini, S; Tarantini, S; Volpini, L, 2017) |
"Gentamicin is a commonly used aminoglycoside antibiotic, whose ototoxicity remains a major problem in clinical use." | 1.42 | The effect of radiotherapy on gentamicin ototoxicity: an animal model. ( Bezdjian, A; Daniel, SJ; Devic, S; Mujica-Mota, MA, 2015) |
"Future implementation of regenerative treatments for sensorineural hearing loss may be hindered by the lack of diagnostic tools that specify the target(s) within the cochlea and auditory nerve for delivery of therapeutic agents." | 1.38 | Mapping auditory nerve firing density using high-level compound action potentials and high-pass noise masking. ( Chertoff, ME; Earl, BR, 2012) |
"Ciclopirox has demonstrated both fungicidal and fungistatic activity in vitro against a broad spectrum of pathogenic fungi." | 1.35 | Ototoxic effect of topical ciclopirox as an antimycotic preparation. ( Akdaş, F; Baylancicek, S; Ciprut, A; Sari, M; Serin, GM; Tutkun, A, 2008) |
" The objective of this study was to evaluate this basic dogma by examining the ototoxic differences between single-dose and 19-day daily dosing of gentamicin over a 60-day period." | 1.35 | Ototoxic effects of single-dose versus 19-day daily-dose gentamicin. ( Blakley, BW; Blakley, L; Gooi, A; Hochman, J; Wellman, M, 2008) |
"ALL-BFM-95 seems to exert an early and reversible toxic effect on the MOCB, whereas its effects on OHCs are minimal and reversible." | 1.34 | Neurotoxicity of BFM-95 on the medial olivocochlear bundle assessed by means of contralateral suppression of 2f1-f2 distortion product otoacoustic emissions. ( Apostolopoulos, N; Ferekidis, E; Giotakis, I; Korres, S; Papadas, T; Psarommatis, I; Riga, M; Varvutsi, M, 2007) |
"The risk of sensorineural hearing loss (SNHL) has been reported to be variable for each protocol." | 1.34 | Effects of a single intratympanic gentamicin injection on Meniere's disease. ( Cho, YS; Chung, KW; Chung, WH; Hong, SH; Kim, JH, 2007) |
" In the chinchilla, co-administration of GM and EA can produce hair cell lesions ranging from a small loss of outer hair cells (OHCs) in the base of the cochlea to complete destruction of all hair cells, depending on dosing parameters." | 1.32 | Time course of efferent fiber and spiral ganglion cell degeneration following complete hair cell loss in the chinchilla. ( Ding, D; Jiang, H; McFadden, SL; Salvi, RJ, 2004) |
"If there was a recurrence of the episodes of vertigo, an additional course of injections was performed." | 1.32 | Hearing loss after intratympanic gentamicin therapy for unilateral Ménière's Disease. ( Martin, E; Perez, N, 2003) |
" Ototoxicity (loss of hearing or balance) is a well-documented adverse effect of aminoglycosides, and severe ototoxic reactions have been noted in patients receiving these drugs by intraperitoneal lavage." | 1.31 | Protection from ototoxicity of intraperitoneal gentamicin in guinea pig. ( Schacht, J; Sha, SH; Sinswat, P; Wu, WJ, 2000) |
"Of these, 68 patients had Meniere's disease; 4 patients had recurrent vertigo after endolymphatic sac surgery and were followed for at least 1 year." | 1.31 | Intratympanic gentamicin therapy for persistent vertigo after endolymphatic sac surgery. ( Leonetti, JP; Marzo, SJ, 2002) |
"In 2 patients with severe Meniere's disease (MD), there was histologic evidence of occlusion of the vein of the vestibular aqueduct (VVA)." | 1.31 | Vascular occlusion in the endolymphatic sac in Meniere's disease. ( Friberg, U; Rask-Andersen, H, 2002) |
"Clinically significant sensorineural hearing loss occurred in 5 (20%) of 25 ears." | 1.30 | Intratympanic gentamicin treatment for Meniere's disease. ( Antonelli, PJ; McFeely, WJ; Rodriguez, FJ; Singleton, GT, 1998) |
"Gentamicin sulfate was given as a single injection (100 mg/kg of body weight subcutaneously), followed 90 minutes later by varying concentrations of ethacrynic acid intravenously." | 1.29 | A sensitive animal model to assess acute and chronic ototoxic effects. ( Lautermann, J; Schacht, J, 1996) |
"Endolymphatic hydrops is usually diagnosed on the basis of clinical symptoms although objective parameters for this disease can be difficult to differentiate from other disorders of the inner ear." | 1.29 | [Animal experiment studies using a low-frequency, phase-delayed masker in inner ear diagnosis]. ( Höhmann, D, 1993) |
"A major risk of the treatment is sensorineural hearing loss." | 1.29 | Intratympanic gentamicin therapy for Menière's disease: preliminary comparison of two regimens. ( Parnes, LS; Toth, AA, 1995) |
"Ipsilateral sensorineural hearing loss (one patient) and external meatal stenosis were the main complications." | 1.28 | Biocompatible implantable antimicrobial release for necrotizing external otitis. ( Kupferberg, A; Ostfeld, EJ, 1991) |
"1." | 1.28 | [Meningitis and hearing damage in children]. ( Begall, K; Hellmund, S; Preibisch-Effenberger, R, 1990) |
"Experimental sensorineural hearing loss was created in six monkeys by ototoxic drug administration (gentamicin) and in three monkeys by exposure to intense sound." | 1.26 | Impedance audiometry in the squirrel monkey. Sensorineural losses. ( Igarashi, M; Jerger, J; Mauldin, L, 1978) |
Research
Studies (94)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 13 (13.83) | 18.7374 |
1990's | 23 (24.47) | 18.2507 |
2000's | 33 (35.11) | 29.6817 |
2010's | 21 (22.34) | 24.3611 |
2020's | 4 (4.26) | 2.80 |
Authors
Authors | Studies |
---|---|
Ding, L | 1 |
Wang, J | 1 |
Jiang, F | 1 |
Kuper, H | 1 |
Bright, T | 1 |
Qin, WZ | 1 |
Zhang, D | 1 |
Lv, Y | 1 |
Li, X | 1 |
Li, Y | 1 |
Song, Y | 1 |
Fan, Z | 1 |
Wang, H | 1 |
Cortada, M | 1 |
Sauteur, L | 1 |
Lanz, M | 1 |
Levano, S | 2 |
Bodmer, D | 4 |
Shamas, IU | 1 |
Covelli, E | 1 |
Volpini, L | 1 |
Filippi, C | 1 |
Tarantini, S | 1 |
Marrone, V | 1 |
Monini, S | 1 |
Barbara, M | 1 |
Jia, Z | 1 |
He, Q | 1 |
Shan, C | 1 |
Li, F | 1 |
Reynard, P | 1 |
Karkas, A | 1 |
Gavid, M | 1 |
Lelonge, Y | 1 |
Bertholon, P | 1 |
Garaycochea, O | 1 |
Domínguez, PD | 1 |
Manrique, M | 1 |
Manrique-Huarte, R | 1 |
Magnan, J | 1 |
Özgirgin, ON | 1 |
Trabalzini, F | 1 |
Lacour, M | 1 |
Escamez, AL | 1 |
Magnusson, M | 1 |
Güneri, EA | 1 |
Guyot, JP | 1 |
Nuti, D | 1 |
Mandalà, M | 1 |
Nichani, J | 1 |
Bruce, IA | 1 |
Mawman, D | 1 |
Khwaja, S | 1 |
Ramsden, R | 1 |
Green, K | 1 |
Chen, FQ | 1 |
Zheng, HW | 1 |
Schacht, J | 5 |
Sha, SH | 2 |
Rhee, CK | 1 |
He, P | 1 |
Jung, JY | 1 |
Ahn, JC | 1 |
Chung, PS | 1 |
Lee, MY | 1 |
Suh, MW | 1 |
Kahya, V | 1 |
Ozucer, B | 1 |
Dogan, R | 1 |
Meric, A | 1 |
Yuksel, M | 1 |
Gedikli, O | 1 |
Ozturan, O | 1 |
D'yakonova, IN | 1 |
Ishanova, YS | 1 |
Rakhmanova, IV | 1 |
Tikhomirov, AM | 1 |
Bezdjian, A | 1 |
Mujica-Mota, MA | 1 |
Devic, S | 1 |
Daniel, SJ | 1 |
Bowsher, B | 1 |
Fuchs, A | 1 |
Zimmermann, L | 1 |
Bickle Graz, M | 1 |
Cherpillod, J | 1 |
Tolsa, JF | 1 |
Buclin, T | 1 |
Giannoni, E | 1 |
Baylancicek, S | 1 |
Serin, GM | 1 |
Ciprut, A | 1 |
Sari, M | 1 |
Akdaş, F | 1 |
Tutkun, A | 1 |
Kyrodimos, E | 1 |
Aidonis, I | 1 |
Sismanis, A | 1 |
Gooi, A | 2 |
Hochman, J | 3 |
Wellman, M | 3 |
Blakley, L | 2 |
Blakley, BW | 3 |
Hussain, AE | 1 |
Yu, Y | 1 |
Szczepek, AJ | 1 |
Haupt, H | 1 |
Mazurek, B | 1 |
Martins, LM | 1 |
Camargos, PA | 1 |
Becker, HM | 1 |
Becker, CG | 1 |
Guimarães, RE | 1 |
Freeland, A | 2 |
Jones, J | 2 |
Mohammed, NK | 1 |
Smyth, AR | 1 |
Mohammed, N | 1 |
Zolotova, TV | 1 |
Panchenko, SN | 1 |
Brand, Y | 1 |
Setz, C | 1 |
Listyo, A | 1 |
Chavez, E | 1 |
Pak, K | 3 |
Sung, M | 1 |
Radojevic, V | 1 |
Ryan, AF | 2 |
Earl, BR | 1 |
Chertoff, ME | 1 |
Brors, D | 2 |
Gloddek, B | 1 |
Ryan, A | 1 |
Bodmer, M | 1 |
Wu, IC | 1 |
Minor, LB | 1 |
Gray, RF | 1 |
Jones, SE | 1 |
Court, I | 1 |
Marzo, SJ | 2 |
Martin, E | 1 |
Perez, N | 2 |
McFadden, SL | 1 |
Ding, D | 1 |
Jiang, H | 1 |
Salvi, RJ | 1 |
Pino Rivero, V | 1 |
Marcos García, M | 1 |
Keituqwa Yáñez, T | 1 |
González Palomino, A | 1 |
Trinidad Ruiz, G | 1 |
Pardo Romero, G | 1 |
Blasco Huelva, A | 1 |
East, JE | 1 |
Foweraker, JE | 1 |
Murgatroyd, FD | 1 |
Nordang, L | 1 |
Anniko, M | 1 |
Rey-Martínez, J | 1 |
Rama-López, J | 1 |
Soledad Boleas, M | 1 |
Artieda, J | 1 |
Robertson, CM | 1 |
Tyebkhan, JM | 1 |
Peliowski, A | 1 |
Etches, PC | 1 |
Cheung, PY | 1 |
Stewart, C | 2 |
Chen, JM | 2 |
Smith, WK | 1 |
Sandooram, D | 1 |
Prinsley, PR | 1 |
Akkuzu, B | 1 |
Ozgirgin, N | 1 |
Ozlüoğlu, LN | 1 |
Colletti, V | 1 |
Carner, M | 1 |
Colletti, L | 1 |
Riga, M | 1 |
Korres, S | 1 |
Psarommatis, I | 1 |
Varvutsi, M | 1 |
Giotakis, I | 1 |
Papadas, T | 1 |
Ferekidis, E | 1 |
Apostolopoulos, N | 1 |
Ishiyama, G | 1 |
Lopez, I | 1 |
Baloh, RW | 1 |
Ishiyama, A | 1 |
De Beer, L | 1 |
Stokroos, R | 1 |
Kingma, H | 1 |
Chung, WH | 1 |
Chung, KW | 1 |
Kim, JH | 1 |
Cho, YS | 1 |
Hong, SH | 1 |
Bernard, PA | 1 |
Pechère, JC | 1 |
Guerit, JM | 1 |
Mahieu, P | 1 |
Houben-Giurgea, S | 1 |
Herbay, S | 1 |
Crifo, S | 1 |
Antonelli, M | 1 |
Gagliardi, M | 1 |
Lucarelli, N | 1 |
Marcolini, P | 1 |
Keene, M | 1 |
Hawke, M | 1 |
Barber, HO | 1 |
Farkashidy, J | 1 |
Tange, RA | 3 |
Huizing, EH | 2 |
Hyde, GE | 1 |
Rubel, EW | 2 |
Trine, MB | 1 |
Lynn, SG | 1 |
Facer, GW | 1 |
Kasperbauer, JL | 1 |
Dreschler, WA | 1 |
Prins, JM | 1 |
Büller, HR | 1 |
Kuijper, EJ | 1 |
Speelman, P | 1 |
Küppers, P | 1 |
Ahrens, H | 1 |
Blessing, R | 1 |
Heidemüller, B | 1 |
Höhmann, D | 1 |
Hiel, H | 1 |
Erre, JP | 1 |
Aurousseau, C | 1 |
Bouali, R | 1 |
Dulon, D | 1 |
Aran, JM | 2 |
Vormann, J | 1 |
Günther, T | 1 |
Lautermann, J | 2 |
McLaren, J | 1 |
Toth, AA | 1 |
Parnes, LS | 1 |
Navaratnam, DS | 1 |
Su, HS | 1 |
Scott, SP | 1 |
Oberholtzer, JC | 1 |
Wong, DL | 1 |
Rutka, JA | 1 |
Silverstein, H | 1 |
Rowan, PT | 1 |
Olds, MJ | 1 |
Rosenberg, SI | 1 |
Hirsch, BE | 1 |
Kamerer, DB | 1 |
McFeely, WJ | 1 |
Singleton, GT | 1 |
Rodriguez, FJ | 1 |
Antonelli, PJ | 1 |
Müller, M | 1 |
Smolders, JW | 1 |
Morgan, M | 1 |
Flood, L | 1 |
Hawthorne, M | 1 |
Raje, S | 1 |
Sinswat, P | 1 |
Wu, WJ | 1 |
Söderman, AC | 1 |
Bergenius, J | 1 |
Bagger-Sjöbäck, D | 1 |
Tjell, C | 1 |
Langius, A | 1 |
Hinojosa, R | 1 |
Nelson, EG | 1 |
Lerner, SA | 1 |
Redleaf, MI | 1 |
Schramm, DR | 1 |
Leonetti, JP | 1 |
Bates, DE | 1 |
Beaumont, SJ | 1 |
Baylis, BW | 1 |
Friberg, U | 1 |
Rask-Andersen, H | 1 |
Jerger, J | 1 |
Mauldin, L | 1 |
Igarashi, M | 1 |
Finitzo-Hieber, T | 2 |
McCracken, GH | 2 |
Roeser, RJ | 1 |
Allen, DA | 1 |
Chrane, DF | 1 |
Morrow, J | 1 |
Forman-Franco, B | 1 |
Abramson, AL | 1 |
Gorvoy, JD | 1 |
Stein, T | 1 |
Reychman, M | 1 |
Jannert, M | 1 |
Ostfeld, EJ | 1 |
Kupferberg, A | 1 |
Portmann, M | 1 |
Tucci, DL | 1 |
Hellmund, S | 1 |
Begall, K | 1 |
Preibisch-Effenberger, R | 1 |
Davey, P | 1 |
Zenner, HP | 1 |
Backus, RM | 1 |
De Groot, JC | 1 |
Klacanský, J | 1 |
Profant, M | 1 |
Kroslák, M | 1 |
Brown, KC | 1 |
Reviews
5 reviews available for gentamicin and Hearing Loss, Sensorineural
Article | Year |
---|---|
European Position Statement on Diagnosis, and Treatment of Meniere's Disease.
Topics: Anti-Bacterial Agents; Betahistine; Consensus; Conservative Treatment; Denervation; Diuretics; Endol | 2018 |
Intratympanic therapies for sensorineural hearing loss and vertigo.
Topics: Anti-Bacterial Agents; Catheterization; Diagnosis, Differential; Gentamicins; Hearing Loss, Sensorin | 2003 |
[Cochlear-vestibular ototoxicity by gentamicin. Report of a case and literature review].
Topics: Anti-Bacterial Agents; Cochlea; Female; Gentamicins; Hearing Loss, Sensorineural; Humans; Injections | 2004 |
Influence of magnesium on drug- and noise-induced inner ear damage. Animal studies.
Topics: Animals; Animals, Newborn; Female; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Hearing Loss, Noi | 1993 |
Role of chemical labyrinthectomy in the treatment of Meniere's disease.
Topics: Ear, Inner; Gentamicins; Hearing Loss, Sensorineural; Humans; Meniere Disease | 1997 |
Trials
6 trials available for gentamicin and Hearing Loss, Sensorineural
Article | Year |
---|---|
Short Term Results of Intra Tympanic Gentamicin and Dexamethasone on Hearing and Tinnitus in Meniere's disease: A Case Control Study.
Topics: Audiometry, Pure-Tone; Case-Control Studies; Dexamethasone; Gentamicins; Glucocorticoids; Hearing; H | 2017 |
Ototoxic drugs and sensorineural hearing loss following severe neonatal respiratory failure.
Topics: Amikacin; Aminoglycosides; Anti-Infective Agents; Audiometry, Pure-Tone; Auditory Threshold; Diureti | 2006 |
[Intratympanic treatment in Meniere's disease: the effect of gentamicin and dexamethasone on vertigo control and hearing].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Dexamethasone; Drug Therapy, Combination; Female; G | 2006 |
Ototoxicity and nephrotoxicity of gentamicin vs netilmicin in patients with serious infections. A randomized clinical trial.
Topics: Adolescent; Adult; Aged; Audiometry; Creatinine; Female; Gentamicins; Hearing Loss, Sensorineural; H | 1995 |
Ototoxicity in neonates treated with gentamicin and kanamycin: results of a four-year controlled follow-up study.
Topics: Audiometry; Bacterial Infections; Child, Preschool; Female; Follow-Up Studies; Gentamicins; Hearing | 1979 |
Prospective controlled evaluation of auditory function in neonates given netilmicin or amikacin.
Topics: Amikacin; Audiometry, Evoked Response; Bilirubin; Clinical Trials as Topic; Creatinine; Female; Foll | 1985 |
Other Studies
83 other studies available for gentamicin and Hearing Loss, Sensorineural
Article | Year |
---|---|
MiR-106a facilitates the sensorineural hearing loss induced by oxidative stress by targeting connexin-43.
Topics: Animals; Antagomirs; Carbenoxolone; Cell Proliferation; Gentamicins; Hearing Loss, Sensorineural; Hu | 2022 |
Etiology of Childhood Bilateral Sensorineural Hearing Loss in Shandong Province, China.
Topics: Adolescent; Anti-Bacterial Agents; Asphyxia Neonatorum; Audiometry; Child; Child, Preschool; China; | 2020 |
Long-term efficacy of triple semicircular canal plugging in the treatment of patients with ipsilateral delayed endolymphatic hydrops.
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Complementary Therapies; Endolymphatic Hydrops; Female | 2021 |
A deep learning approach to quantify auditory hair cells.
Topics: Animals; Deep Learning; Gentamicins; Hair Cells, Auditory; Hearing Loss, Sensorineural; Mice; Organ | 2021 |
Intralabyrinthine Vestibular Schwannoma Responsive to Intratympanic Gentamicin Treatment.
Topics: Adult; Anti-Bacterial Agents; Female; Gentamicins; Hearing Loss, Sensorineural; Humans; Neuroma, Aco | 2017 |
Tauroursodeoxycholic acid attenuates gentamicin-induced cochlear hair cell death in vitro.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Biomarkers; Cell Line; Cell Survival; Cochlea; Endoplasmi | 2018 |
Delayed endolymphatic hydrops. Special emphasis on nystagmus associated with episodes and contribution of chemical labyrinthectomy.
Topics: Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Deafness; Endolymphatic Hydrops; Female; Gentamic | 2018 |
Cochlear-Internal Canal and Cochlear-Facial Dehiscence: A Novel Entity.
Topics: Anti-Bacterial Agents; Cerebrospinal Fluid Leak; Cochlea; Cochlear Implantation; Ear Canal; Gentamic | 2018 |
Cochlear implantation in patients deafened by ototoxic drugs.
Topics: Adolescent; Adult; Audiometry; Auditory Threshold; Child; Child, Preschool; Cochlear Implantation; C | 2013 |
Mitochondrial peroxiredoxin 3 regulates sensory cell survival in the cochlea.
Topics: Animals; Cell Death; Cell Survival; Free Radical Scavengers; Gene Expression Regulation; Gentamicins | 2013 |
Effect of low-level laser treatment on cochlea hair-cell recovery after ototoxic hearing loss.
Topics: Animals; Ear Canal; Furosemide; Gentamicins; Hair Cells, Auditory; Hearing Loss, Sensorineural; Lase | 2013 |
Pomegranate extract: a potential protector against aminoglycoside ototoxicity.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antioxidants; Cochlea; Female; Gentamicins; Hearing | 2014 |
Effect of gentamicin on the auditory analyzer in sexually immature animals.
Topics: Acoustic Stimulation; Animals; Anti-Bacterial Agents; Ear, Inner; Evoked Potentials, Auditory, Brain | 2014 |
The effect of radiotherapy on gentamicin ototoxicity: an animal model.
Topics: Animals; Biopsy, Needle; Cochlea; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Res | 2015 |
Sensorineural deafness following routine transurethral resection of the prostate.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Australia; Dexamethasone; Disability Evaluation; Gen | 2015 |
Gentamicin Exposure and Sensorineural Hearing Loss in Preterm Infants.
Topics: Female; Gentamicins; Hearing Loss, Sensorineural; Humans; Incidence; Infant Nutrition Disorders; Inf | 2016 |
Ototoxic effect of topical ciclopirox as an antimycotic preparation.
Topics: Administration, Topical; Animals; Antifungal Agents; Brain Stem; Ciclopirox; Ear, External; Evoked P | 2008 |
Hearing results following intratympanic gentamicin perfusion for Ménière's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Ge | 2009 |
Ototoxic effects of single-dose versus 19-day daily-dose gentamicin.
Topics: Animals; Auditory Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administ | 2008 |
Differences in Ototoxicity across Species.
Topics: Animals; Auditory Threshold; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Dr | 2008 |
Geldanamycin induces production of heat shock protein 70 and partially attenuates ototoxicity caused by gentamicin in the organ of Corti explants.
Topics: Animals; Benzoquinones; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinica | 2009 |
Hearing loss in cystic fibrosis.
Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Audiometry, Pure-Tone; Child; Child, Preschool; Cystic | 2010 |
Sensorineural deafness in Tanzanian children--is ototoxicity a significant cause? A pilot study.
Topics: Anti-Bacterial Agents; Antimalarials; Case-Control Studies; Child; Child, Preschool; Craniocerebral | 2010 |
Minimizing the toxicity of aminoglycosides in cystic fibrosis.
Topics: Acute Kidney Injury; Aminoglycosides; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; DNA, | 2010 |
"Sensorineural deafness in Tanzanian children--is ototoxicity a significant cause? A pilot study" by Freeland et al. [Int. J. Pediatr. Otorhinolaryngol. 74 (2) (2010) 516-519].
Topics: Anti-Bacterial Agents; Antimalarials; Child; Gentamicins; Hearing Loss, Sensorineural; Humans; Malar | 2010 |
[Experimental sensorineural loss of hearing of ototoxic origin in animals: apoptotic mechanism of cell death in the spiral organ].
Topics: Animals; Apoptosis; Disease Models, Animal; Gentamicins; Hearing Loss, Sensorineural; Immobilization | 2010 |
Simvastatin protects auditory hair cells from gentamicin-induced toxicity and activates Akt signaling in vitro.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Gentamicins; Hair Cells, Auditory; Hearing Loss, | 2011 |
Mapping auditory nerve firing density using high-level compound action potentials and high-pass noise masking.
Topics: Acoustic Stimulation; Action Potentials; Animals; Auditory Threshold; Central Nervous System Agents; | 2012 |
Rescue of auditory hair cells from aminoglycoside toxicity by Clostridium difficile toxin B, an inhibitor of the small GTPases Rho/Rac/Cdc42.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; cdc42 GTP-Binding Protein; Enz | 2002 |
Gentamicin-induced hair cell death is not dependent on the apoptosis receptor Fas.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Cell Death; Culture Techniques; fas Receptor; Gentamicins | 2003 |
Long-term hearing outcome in patients receiving intratympanic gentamicin for Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Follow-Up Studies; Gentamicins; H | 2003 |
Cochlear implantation for progressive hearing loss.
Topics: Adolescent; Age Factors; Anti-Bacterial Agents; Audiometry, Pure-Tone; Child; Cochlear Implantation; | 2003 |
Hearing loss after intratympanic gentamicin therapy for unilateral Ménière's Disease.
Topics: Audiometry; Drug Administration Schedule; Ear, Middle; Female; Follow-Up Studies; Gentamicins; Heari | 2003 |
Time course of efferent fiber and spiral ganglion cell degeneration following complete hair cell loss in the chinchilla.
Topics: Acetylcholinesterase; Action Potentials; Animals; Cell Count; Cell Death; Chinchilla; Cochlear Micro | 2004 |
Gentamicin induced ototoxicity during treatment of enterococcal endocarditis: resolution with substitution by netilmicin.
Topics: Aged; Anti-Bacterial Agents; Endocarditis, Bacterial; Equipment Contamination; Gentamicins; Gram-Pos | 2005 |
Nitro-L-arginine methyl ester: a potential protector against gentamicin ototoxicity.
Topics: Animals; Anti-Bacterial Agents; Enzyme Inhibitors; Evoked Potentials, Auditory, Brain Stem; Gentamic | 2005 |
A report of two cases of unilateral vestibulopathie after systemic ototoxic treatment.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry; Caloric Tests; Electrooculography; Evoked Potentials | 2005 |
Acute bilateral aminoglycoside-induced hearing loss following nonotologic surgery.
Topics: Adult; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Gait Ataxia; Gentamicins; Hearing Loss, | 2006 |
Intratympanic gentamicin treatment in Meniere's disease: patients' experiences and outcomes.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Tone; Auditory Threshold; Fe | 2006 |
Prevention of aminoglycoside-induced sensorineural hearing loss.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Disease Models, Animal; Drug Resistance; Evoked Potent | 2006 |
Auditory results after vestibular nerve section and intratympanic gentamicin for Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Gentamicins; Hearing Loss, Sensor | 2007 |
Neurotoxicity of BFM-95 on the medial olivocochlear bundle assessed by means of contralateral suppression of 2f1-f2 distortion product otoacoustic emissions.
Topics: Acoustic Stimulation; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Audiome | 2007 |
Histopathology of the vestibular end organs after intratympanic gentamicin failure for Meniere's disease.
Topics: Administration, Topical; Anti-Bacterial Agents; Atrophy; Ear, Inner; Gentamicins; Hair Cells, Audito | 2007 |
Acute bilateral aminoglycoside-induced hearing loss following nonotologic surgery.
Topics: Acute Disease; Adult; Anti-Bacterial Agents; Female; Gentamicins; Hearing Loss, Bilateral; Hearing L | 2007 |
Intratympanic gentamicin therapy for intractable Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Caloric Tests; Drug Administration Schedu | 2007 |
Effects of a single intratympanic gentamicin injection on Meniere's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Caloric Tests; Dose-Response Relationship | 2007 |
Does incubator noise increase risks of aminoglycoside ototoxicity?
Topics: Aminoglycosides; Animals; Animals, Newborn; Anti-Bacterial Agents; Auditory Fatigue; Auditory Thresh | 1984 |
The influence of ototoxic drugs on brainstem auditory evoked potentials in man.
Topics: Acoustic Stimulation; Adult; Amikacin; Brain Stem; Cochlear Microphonic Potentials; Evoked Potential | 1981 |
Ototoxicity of aminoglucoside antibiotics in long-term treatment for cystic fibrosis.
Topics: Adolescent; Adult; Aminoglycosides; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; | 1980 |
Histopathological findings in clinical gentamicin ototoxicity.
Topics: Ear, Inner; Ear, Middle; Female; Gentamicins; Hearing Loss, Sensorineural; Humans; Middle Aged; Neph | 1982 |
Hearing loss and inner ear changes in a patient suffering from severe gentamicin ototoxicity.
Topics: Adult; Cochlea; Deafness; Female; Gentamicins; Hair Cells, Auditory; Hearing Loss, Sensorineural; Hu | 1980 |
Mitochondrial role in hair cell survival after injury.
Topics: Animals; Animals, Newborn; Awards and Prizes; Cell Survival; Chickens; Chloramphenicol; Gentamicins; | 1995 |
Intratympanic gentamicin treatment: preliminary results in two patients with Menière's disease.
Topics: Audiometry, Pure-Tone; Auditory Threshold; Endolymphatic Hydrops; Gentamicins; Hearing Loss, Sensori | 1995 |
[Continuous intratympanic gentamycin infusion in Menière disease].
Topics: Adult; Audiometry, Pure-Tone; Auditory Threshold; Dose-Response Relationship, Drug; Drug Administrat | 1994 |
[Ototoxicity of locally administered aminoglycoside antibiotics].
Topics: Administration, Topical; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Auditory Threshold; Bur | 1994 |
[Animal experiment studies using a low-frequency, phase-delayed masker in inner ear diagnosis].
Topics: Animals; Audiometry, Evoked Response; Auditory Threshold; Cochlea; Cochlear Microphonic Potentials; | 1993 |
Gentamicin uptake by cochlear hair cells precedes hearing impairment during chronic treatment.
Topics: Animals; Cochlea; Enzyme-Linked Immunosorbent Assay; Evoked Potentials, Auditory; Female; Gentamicin | 1993 |
Glutathione protection against gentamicin ototoxicity depends on nutritional status.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Ascorbic Acid; Cochlea; Diet; Dietary Proteins | 1995 |
Intratympanic gentamicin therapy for Menière's disease: preliminary comparison of two regimens.
Topics: Audiometry, Pure-Tone; Caloric Tests; Clinical Protocols; Female; Gentamicins; Hearing Loss, Sensori | 1995 |
A sensitive animal model to assess acute and chronic ototoxic effects.
Topics: Acute Disease; Animals; Anti-Bacterial Agents; Auditory Threshold; Diet, Protein-Restricted; Disease | 1996 |
Proliferation in the auditory receptor epithelium mediated by a cyclic AMP-dependent signaling pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbazoles; Chickens; | 1996 |
Do aminoglycoside otic preparations cause ototoxicity in the presence of tympanic membrane perforations?
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Ear, Inner; Female; Gentamicins; Hearin | 1997 |
Inner ear perfusion and the role of round window patency.
Topics: Aged; Anti-Bacterial Agents; Chemotherapy, Cancer, Regional Perfusion; Endoscopy; Female; Gentamicin | 1997 |
Intratympanic gentamicin treatment for Meniere's disease.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Ton | 1998 |
Hair cell regeneration after local application of gentamicin at the round window of the cochlea in the pigeon.
Topics: Acoustic Stimulation; Animals; Anti-Bacterial Agents; Audiometry; Auditory Threshold; Basilar Membra | 1998 |
Chemical labyrinthectomy and cochlear implantation for Menière's disease--an effective treatment or a last resort?
Topics: Audiometry, Pure-Tone; Cochlear Implantation; Combined Modality Therapy; Ear, Inner; Female; Gentami | 1999 |
Protection from ototoxicity of intraperitoneal gentamicin in guinea pig.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Auditory Threshold; Blood Urea Nitrogen; Creatinine; G | 2000 |
Patients' subjective evaluations of quality of life related to disease-specific symptoms, sense of coherence, and treatment in Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Cross-Sectional Studies; Endolymphatic Sac; Female; Gentamicins; | 2001 |
Aminoglycoside ototoxicity: a human temporal bone study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Audiometry, Pure-Tone; Cell Death; Dose | 2001 |
Intratympanic gentamicin therapy for persistent vertigo after endolymphatic sac surgery.
Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Audiometry, Pure-Tone; Electronystagmography; | 2002 |
Ototoxicity induced by gentamicin and furosemide.
Topics: Anti-Bacterial Agents; Community-Acquired Infections; Diuretics; Drug Synergism; Female; Furosemide; | 2002 |
Vascular occlusion in the endolymphatic sac in Meniere's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry; Biopsy; Calcinosis; Case-Control Studies; Combined M | 2002 |
Impedance audiometry in the squirrel monkey. Sensorineural losses.
Topics: Acoustic Impedance Tests; Acoustic Stimulation; Animals; Gentamicins; Haplorhini; Hearing Loss, Nois | 1978 |
Cystic fibrosis and hearing loss.
Topics: Acoustic Impedance Tests; Adolescent; Adult; Audiometry; Auditory Threshold; Child; Cystic Fibrosis; | 1979 |
[Local administration of gentamicin caused hearing loss].
Topics: Administration, Topical; Aged; Female; Gentamicins; Hearing Loss, Sensorineural; Humans; Tinnitus | 1992 |
Biocompatible implantable antimicrobial release for necrotizing external otitis.
Topics: Aged; Aged, 80 and over; Biocompatible Materials; Drug Evaluation; Drug Implants; Female; Gentamicin | 1991 |
[Synergism between noise and ototoxic drugs: new experimental data].
Topics: Animals; Ethacrynic Acid; Gentamicins; Guinea Pigs; Hearing; Hearing Loss, Sensorineural; Noise | 1990 |
Physiologic status of regenerated hair cells in the avian inner ear following aminoglycoside ototoxicity.
Topics: Animals; Auditory Threshold; Chickens; Evoked Potentials, Auditory; Gentamicins; Hair Cells, Auditor | 1990 |
[Meningitis and hearing damage in children].
Topics: Adolescent; Ampicillin; Audiometry, Evoked Response; Audiometry, Pure-Tone; Child; Child, Preschool; | 1990 |
Aminoglycosides and neonatal deafness.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Gentamicins; Hearing Loss, Sensorineur | 1985 |
[Hearing loss caused by aminoglycoside antibiotics: affect on the membrane component PIP2 in outer hair cells as the mechanism of action].
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Binding Sites; Cells, Cultured; Gentamicins; Guinea | 1986 |
Pathological findings in the human auditory system following long-standing gentamicin ototoxicity.
Topics: Adult; Audiometry, Pure-Tone; Cochlea; Gentamicins; Hearing Loss, Sensorineural; Humans; Injections, | 1987 |
[The effect of gentamycin on the ear].
Topics: Aged; Ear, Inner; Gentamicins; Hearing Loss, Sensorineural; Humans; Male | 1987 |