Page last updated: 2024-10-27

gentamicin and Hearing Loss, High-Frequency

gentamicin has been researched along with Hearing Loss, High-Frequency in 10 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Hearing Loss, High-Frequency: Hearing loss in frequencies above 1000 hertz.

Research Excerpts

ExcerptRelevanceReference
"Although pulmonary infections caused by Pseudomonas aeruginosa can hardly be eradicated in patients with cystic fibrosis (CF, the most common genetic disease among Caucasians), these patients are mainly treated with intravenous and nebulized tobramycin."3.70Loss of spiral ganglion cells as primary manifestation of aminoglycoside ototoxicity. ( Paparella, MM; Schachern, PA; Sone, M, 1998)
"A 65-year-old man with end-stage renal disease on continuous ambulatory peritoneal dialysis accidentally received an acute massive overdose of gentamicin as a treatment of peritonitis."3.69Acute massive gentamicin intoxication in a patient with end-stage renal disease. ( James, SH; Lien, YH; Lu, CM, 1996)
" Thus, it remains to be determined whether presbyacusis sensitizes those hair cells which it does not destroy to toxic damage."1.28Screening for aminoglycoside auditory toxicity in the old. ( Cheung, R; Clark, P; Deshmukh, AA; Dobbs, RJ; Dobbs, SM; Nicholson, PW; O'Neill, CJ, 1990)
"Gentamicin has a 'typical starting point' of degeneration on the basilar membrane."1.27Differences in the cochlear degeneration pattern in the guinea pig as a result of gentamicin and cis-platinum intoxication. ( Tange, RA, 1984)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's7 (70.00)18.2507
2000's0 (0.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Garcia-Huerta, P1
Rivas, A1
Hetz, C1
Oishi, N1
Duscha, S1
Boukari, H1
Meyer, M1
Xie, J1
Wei, G1
Schrepfer, T1
Roschitzki, B1
Boettger, EC1
Schacht, J1
Tange, RA2
Kawashiro, N1
Tsuchihashi, N1
Koga, K1
Ito, Y1
Kawano, H1
Lu, CM1
James, SH1
Lien, YH1
Sone, M1
Schachern, PA1
Paparella, MM1
Fausti, SA1
Henry, JA1
Schaffer, HI1
Olson, DJ1
Frey, RH1
McDonald, WJ1
Girod, DA1
Tucci, DL1
Rubel, EW1
van der Hulst, RJ1
Boeschoten, EW1
Nielsen, FW1
Struijk, DG1
Dreschler, WD1
Cheung, R1
Clark, P1
Nicholson, PW1
Deshmukh, AA1
O'Neill, CJ1
Dobbs, SM1
Dobbs, RJ1

Other Studies

10 other studies available for gentamicin and Hearing Loss, High-Frequency

ArticleYear
Stressing out the ER in aminoglycoside-induced hearing loss.
    Cell death & disease, 2015, May-14, Volume: 6

    Topics: Animals; DNA-Binding Proteins; Endoplasmic Reticulum Stress; Female; Gentamicins; Hearing Loss, High

2015
XBP1 mitigates aminoglycoside-induced endoplasmic reticulum stress and neuronal cell death.
    Cell death & disease, 2015, May-14, Volume: 6

    Topics: Animals; CCAAT-Enhancer-Binding Proteins; Cell Line; DNA-Binding Proteins; Endoplasmic Reticulum; En

2015
Differences in the cochlear degeneration pattern in the guinea pig as a result of gentamicin and cis-platinum intoxication.
    Clinical otolaryngology and allied sciences, 1984, Volume: 9, Issue:6

    Topics: Animals; Basilar Membrane; Cisplatin; Cochlea; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Hair

1984
Idiopathic deafness or hearing loss of unknown etiology following discharge from the NICU.
    Acta oto-laryngologica. Supplementum, 1994, Volume: 514

    Topics: Child, Preschool; Deafness; Dyspnea; Evoked Potentials, Auditory, Brain Stem; Extracorporeal Membran

1994
Acute massive gentamicin intoxication in a patient with end-stage renal disease.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1996, Volume: 28, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Drug Overdose; Gentamicins; Hearing Loss, High-Frequency; Hemoperfusion

1996
Loss of spiral ganglion cells as primary manifestation of aminoglycoside ototoxicity.
    Hearing research, 1998, Volume: 115, Issue:1-2

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Gentamicins; Hair Cells, Auditory;

1998
High-frequency audiometric monitoring for early detection of aminoglycoside ototoxicity.
    The Journal of infectious diseases, 1992, Volume: 165, Issue:6

    Topics: Amikacin; Anti-Bacterial Agents; Audiometry; Gentamicins; Hearing Loss; Hearing Loss, Bilateral; Hea

1992
Anatomical correlates of functional recovery in the avian inner ear following aminoglycoside ototoxicity.
    The Laryngoscope, 1991, Volume: 101, Issue:11

    Topics: Animals; Cell Count; Chickens; Cochlea; Disease Models, Animal; Evoked Potentials, Auditory; Gentami

1991
Ototoxicity monitoring with ultra-high frequency audiometry in peritoneal dialysis patients treated with vancomycin or gentamicin.
    ORL; journal for oto-rhino-laryngology and its related specialties, 1991, Volume: 53, Issue:1

    Topics: Audiometry; Female; Gentamicins; Hearing Loss, High-Frequency; Humans; Middle Aged; Monitoring, Phys

1991
Screening for aminoglycoside auditory toxicity in the old.
    British journal of clinical pharmacology, 1990, Volume: 30, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry; Bacterial Infections; Female; Gentamicin

1990