gentamicin has been researched along with Gangrene in 39 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Gangrene: Death and putrefaction of tissue usually due to a loss of blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with gangrenous or perforated appendicitis were treated with cefoxitin or a combination of clindamycin and gentamicin for a minimum of five post-operative days." | 7.67 | Antimicrobial management of surgically treated gangrenous or perforated appendicitis: comparison of cefoxitin and clindamycin-gentamicin. ( Levine, BA; Sirinek, KR, 1987) |
| "A matched case-control study of the efficacy of gentamicin dosage adjustment through the use of pharmacokinetic analysis of serum drug concentrations in patients treated by appendectomy for perforated or gangrenous appendicitis was performed." | 7.67 | Matched case-control study of adjusted versus nonadjusted gentamicin dosing in perforated and gangrenous appendicitis. ( Appleman, MD; Berne, TV; Cheetham, TC; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1986) |
| " Ticarcillin and clavulanic acid is a safe and effective alternative to gentamicin and clindamycin in the treatment of secondary bacterial peritonitis and offers advantages in dosing simplicity and freedom from ototoxic and nephrotoxic effects." | 6.67 | A randomized trial of ticarcillin and clavulanate versus gentamicin and clindamycin in patients with complicated appendicitis. ( Levine, BA; Sirinek, KR, 1991) |
| "Patients with gangrenous or perforated appendicitis were treated with cefoxitin or a combination of clindamycin and gentamicin for a minimum of five post-operative days." | 3.67 | Antimicrobial management of surgically treated gangrenous or perforated appendicitis: comparison of cefoxitin and clindamycin-gentamicin. ( Levine, BA; Sirinek, KR, 1987) |
| "A matched case-control study of the efficacy of gentamicin dosage adjustment through the use of pharmacokinetic analysis of serum drug concentrations in patients treated by appendectomy for perforated or gangrenous appendicitis was performed." | 3.67 | Matched case-control study of adjusted versus nonadjusted gentamicin dosing in perforated and gangrenous appendicitis. ( Appleman, MD; Berne, TV; Cheetham, TC; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1986) |
| "The relationships between resistant pathogens, serum levels of gentamicin, and the outcomes of gangrenous or perforated appendicitis were analyzed in 147 patients." | 3.66 | Perforated and gangrenous appendicitis: an analysis of antibiotic failures. ( Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Kern, JW; Yellin, AE, 1983) |
| " Children treated with ampicillin, gentamicin, and clindamycin had markedly fewer wound infections and abscesses and were able to tolerate a diet and go home sooner than those receiving ampicillin and/or gentamicin." | 3.66 | Rational use of antibiotics for perforated appendicitis in childhood. ( Buck, JR; David, IB; Filler, RM, 1982) |
| "Five burn patients with ecthyma gangrenosum were treated with gentamicin sulfate in an individualized aminoglycoside regimen." | 3.66 | Ecthyma gangrenosum: survival with individualized antibiotic therapy. ( Solem, LD; Strate, RG; Zaske, D, 1979) |
| "The use of gentamicin-polymethylmethacrylate (PMMA) bead chains permits the depositing of a high dose of gentamicin at the place of the infection." | 3.66 | [What advantage are there in using gentamycin-PMMA-chains in the treatment of posttraumatic osteomyelitis, osteoarthritis and soft tissue infections?]. ( Eberle, H, 1978) |
| "Cefepime is a new extended-spectrum cephalosporin with gram-positive and gram-negative coverage including Staphylococcus aureus and Pseudomonas aeruginosa." | 2.67 | Analysis of cefepime tissue penetration into human appendix. ( Appleman, MD; Berne, TV; Chin, A; Gill, MA; Heseltine, PN; Knupp, CA; Okamoto, MP; Sclar, DA; Yellin, AE, 1991) |
| " Ticarcillin and clavulanic acid is a safe and effective alternative to gentamicin and clindamycin in the treatment of secondary bacterial peritonitis and offers advantages in dosing simplicity and freedom from ototoxic and nephrotoxic effects." | 2.67 | A randomized trial of ticarcillin and clavulanate versus gentamicin and clindamycin in patients with complicated appendicitis. ( Levine, BA; Sirinek, KR, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (87.18) | 18.7374 |
| 1990's | 2 (5.13) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, C | 1 |
| You, JX | 1 |
| Chen, YX | 1 |
| Zhu, WF | 1 |
| Wang, Y | 1 |
| Lv, PP | 1 |
| Zhao, F | 1 |
| Li, HY | 1 |
| Li, L | 1 |
| Wuyts, L | 1 |
| Wojciechowski, M | 1 |
| Maes, P | 1 |
| Matthieu, L | 1 |
| Lambert, J | 1 |
| Aerts, O | 1 |
| Le Falher, G | 1 |
| Makinson, A | 1 |
| Eden, A | 1 |
| Lesnik, A | 1 |
| Le Moing, V | 1 |
| Reynes, J | 1 |
| Berne, TV | 7 |
| Yellin, AW | 1 |
| Appleman, MD | 7 |
| Heseltine, PN | 7 |
| Yellin, AE | 6 |
| Gill, MA | 7 |
| Chenella, FC | 5 |
| Kern, JW | 1 |
| Johnson, DA | 1 |
| Aulicino, PL | 1 |
| Newby, JG | 1 |
| Abdel-Lah, BA | 1 |
| Fernández Alvarez, D | 1 |
| Lozano Sánchez, F | 1 |
| Alvarez Aparicio, E | 1 |
| Gómez Alonso, A | 1 |
| Salazar A-Villalobos, V | 1 |
| Bruce, M | 1 |
| Longoni, C | 1 |
| Viotti, G | 1 |
| Rusconi, L | 1 |
| Rippa, A | 1 |
| Ferri, M | 1 |
| David, IB | 1 |
| Buck, JR | 1 |
| Filler, RM | 1 |
| Treister, G | 1 |
| Frankl, O | 1 |
| Cohen, S | 1 |
| Stein, R | 1 |
| Solem, LD | 1 |
| Zaske, D | 1 |
| Strate, RG | 1 |
| O'Reilly, GV | 1 |
| Dee, PM | 1 |
| Otteni, GV | 1 |
| Eberle, H | 1 |
| Knight, L | 1 |
| Fraser, RG | 1 |
| Robson, HG | 1 |
| Cameron, DI | 1 |
| Stewart, JD | 1 |
| Slack, RC | 1 |
| Lewis, CL | 1 |
| Singh, S | 1 |
| Lynfield, YL | 1 |
| Gruber, H | 1 |
| Miller, JJ | 1 |
| Fries, JF | 1 |
| Stone, HH | 1 |
| Hutchinson, PE | 1 |
| Summerly, R | 1 |
| Lawson, LJ | 1 |
| Okamoto, MP | 1 |
| Chin, A | 1 |
| Knupp, CA | 1 |
| Sclar, DA | 1 |
| Sirinek, KR | 2 |
| Levine, BA | 2 |
| Riggio, CE | 1 |
| Fisher, DF | 1 |
| Clagett, GP | 1 |
| Fry, RE | 1 |
| Humble, TH | 1 |
| Fry, WJ | 1 |
| Robbs, JV | 1 |
| Reddy, E | 1 |
| Ray, R | 1 |
| Pricolo, R | 1 |
| Nicita, E | 1 |
| Lacchini, C | 1 |
| Galasso, P | 1 |
| Cerri, G | 1 |
| Leedom, JM | 1 |
| Hurst, AK | 1 |
| Iseri, KT | 1 |
| Noguchi, JK | 1 |
| Gilman, TM | 1 |
| Jelliffe, RW | 1 |
| Cheetham, TC | 1 |
| Feldman, MJ | 1 |
| Sharon, D | 1 |
| Sweeney, JL | 1 |
| Hewett, P | 1 |
| Riddell, P | 1 |
| Hoffmann, DC | 1 |
| Thorsteinsson, SB | 1 |
| Minuth, JN | 1 |
| Musher, DM | 1 |
| Lewis, JE | 1 |
| Kraeger, RR | 1 |
| Danis, RK | 1 |
| Graybill, JR | 1 |
| Pierson, DN | 1 |
| Charache, P | 1 |
| von Graevenitz, A | 1 |
| Carrington, GO | 1 |
| Bray, DA | 1 |
| Qureshi, ME | 1 |
| Puri, SP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Negative Pressure Wound Therapy on Wound Healing in Major Amputations[NCT04618406] | 160 participants (Anticipated) | Interventional | 2021-11-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for gentamicin and Gangrene
| Article | Year |
|---|---|
Juvenile ecthyma gangrenosum caused by Pseudomonas aeruginosa revealing an underlying neutropenia: case report and review of the literature.
Topics: Anti-Bacterial Agents; Ecthyma; Female; Gangrene; Gentamicins; Granulocyte Colony-Stimulating Factor | 2019 |
8 trials available for gentamicin and Gangrene
| Article | Year |
|---|---|
Antibiotic management of surgically treated gangrenous or perforated appendicitis. Comparison of gentamicin and clindamycin versus cefamandole versus cefoperazone.
Topics: Adolescent; Adult; Aged; Appendicitis; Cefamandole; Cefoperazone; Cephalosporins; Clindamycin; Clini | 1982 |
[Logical use of prophylactic antibacterial agents in infectious post-appendectomy complications. A controlled clinical trial].
Topics: Appendectomy; Appendicitis; Bacterial Infections; Child; Clindamycin; Clinical Trials as Topic; Fema | 1982 |
Analysis of cefepime tissue penetration into human appendix.
Topics: Adolescent; Adult; Appendectomy; Appendicitis; Appendix; Ascitic Fluid; Cefepime; Cephalosporins; Cl | 1991 |
A randomized trial of ticarcillin and clavulanate versus gentamicin and clindamycin in patients with complicated appendicitis.
Topics: Abdomen; Abscess; Adolescent; Adult; Anti-Bacterial Agents; Appendicitis; beta-Lactamase Inhibitors; | 1991 |
The role of Pseudomonas species in patients treated with ampicillin and Sulbactam for gangrenous and perforated appendicitis.
Topics: Adult; Ampicillin; Appendicitis; Clindamycin; Double-Blind Method; Drug Therapy, Combination; Female | 1985 |
One-stage versus two-stage amputation for wet gangrene of the lower extremity: a randomized study.
Topics: Aged; Amputation, Surgical; Clindamycin; Foot Diseases; Gangrene; Gentamicins; Humans; Middle Aged; | 1988 |
Antibiotic prophylaxis in aortic and peripheral arterial surgery in the presence of infected extremity lesions. Results of a prospective evaluation.
Topics: Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Cefotaxime; Cloxacillin; Drug Therapy, | 1988 |
Cost analysis of antibiotics in the management of perforated or gangrenous appendicitis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Appendicitis; Cefamandole; Cefoperazone; Clindamycin; Cost | 1986 |
30 other studies available for gentamicin and Gangrene
| Article | Year |
|---|---|
Effect of Induced Membrane Formation Followed by Polymethylmethacrylate Implantation on Diabetic Foot Ulcer Healing When Revascularization Is Not Feasible.
Topics: Abscess; Aged; Amputation, Surgical; Anti-Bacterial Agents; Bone Cements; Case-Control Studies; Debr | 2019 |
[Two cases of pulmonary gangrene in HIV-infected patients: favorable outcome without surgery].
Topics: Acetamides; Adult; Alcoholism; Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Gangre | 2011 |
Perforated and gangrenous appendicitis: an analysis of antibiotic failures.
Topics: Anti-Bacterial Agents; Appendicitis; Bacteroides fragilis; Bacteroides Infections; Cefamandole; Cefo | 1983 |
Bacillus cereus-induced myonecrosis.
Topics: Adult; Amputation, Traumatic; Bacillus cereus; Bacterial Infections; Gangrene; Gentamicins; Humans; | 1984 |
A case of Fournier's gangrene.
Topics: Gangrene; Genital Diseases, Male; Gentamicins; Humans; Male; Metronidazole; Middle Aged; Penicillin | 1980 |
[Use of hyperbaric oxygen therapy in a case of inguino-genital gangrene].
Topics: Gangrene; Gentamicins; Groin; Humans; Hyperbaric Oxygenation; Lincomycin; Liver Cirrhosis, Alcoholic | 1982 |
Rational use of antibiotics for perforated appendicitis in childhood.
Topics: Abscess; Adolescent; Ampicillin; Anti-Bacterial Agents; Appendicitis; Child; Child, Preschool; Clind | 1982 |
Metastic gangrene of the lid in Pseudomonas septicemia.
Topics: Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Eyelid Diseases; Female; Gangrene; Gentamicins; H | 1975 |
Ecthyma gangrenosum: survival with individualized antibiotic therapy.
Topics: Adolescent; Burns; Carbenicillin; Child, Preschool; Ecthyma; Gangrene; Gentamicins; Humans; Infant; | 1979 |
Gangrene of the lung: successful medical management of three patients.
Topics: Adult; Ampicillin; Anti-Bacterial Agents; Clindamycin; Female; Gangrene; Gentamicins; Humans; Lung D | 1978 |
[What advantage are there in using gentamycin-PMMA-chains in the treatment of posttraumatic osteomyelitis, osteoarthritis and soft tissue infections?].
Topics: Arteriosclerosis; Connective Tissue; Gangrene; Gentamicins; Humans; Infections; Methylmethacrylates; | 1978 |
Massive pulmonary gangrene: a severe complication of Klebsiella pneumonia.
Topics: Adult; Cephalothin; Cloxacillin; Gangrene; Gentamicins; Humans; Kanamycin; Klebsiella Infections; Kl | 1975 |
Letter: Massive pulmonary gangrene.
Topics: Adult; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Gangrene; Gentamicins; Humans; Kleb | 1975 |
Fournier's gangrene of the scrotum.
Topics: Acremonium; Ampicillin; Gangrene; Genital Diseases, Male; Gentamicins; Humans; Male; Methicillin; Mi | 1975 |
Simultaneous vasculitis in a mother and newborn infant.
Topics: Adult; Arthritis; Aspirin; Female; Gangrene; Gentamicins; Heparin; Humans; Infant, Newborn; Infant, | 1975 |
Bacterial flora of appendicitis in children.
Topics: Aerobiosis; Amikacin; Anaerobiosis; Appendectomy; Appendicitis; Ascitic Fluid; Bacteria; Cephalothin | 1976 |
Postoperative progressive gangrene: a reminder.
Topics: Adult; Appendectomy; Chloramphenicol; Female; Gangrene; Gentamicins; Humans; Postoperative Complicat | 1976 |
[Fournier's gangrene (gangrene of the external genitalia). Presentation of a case].
Topics: Aged; Ampicillin; Clindamycin; Diverticulitis, Colonic; Drug Therapy, Combination; Gangrene; Genital | 1988 |
Imipenem therapy for perforated and gangrenous appendicitis.
Topics: Adult; Aged; Appendectomy; Appendicitis; Ascitic Fluid; Cilastatin; Clindamycin; Cyclopropanes; Drug | 1986 |
Antimicrobial management of surgically treated gangrenous or perforated appendicitis: comparison of cefoxitin and clindamycin-gentamicin.
Topics: Adolescent; Adult; Aged; Appendectomy; Appendicitis; Appendix; Cefoxitin; Child; Child, Preschool; C | 1987 |
Comparison of four methods for predicting serum gentamicin concentrations in surgical patients with perforated or gangrenous appendicitis.
Topics: Adult; Appendicitis; Female; Gangrene; Gentamicins; Humans; Intestinal Perforation; Male | 1987 |
Matched case-control study of adjusted versus nonadjusted gentamicin dosing in perforated and gangrenous appendicitis.
Topics: Adult; Appendicitis; Dose-Response Relationship, Drug; Female; Gangrene; Gentamicins; Humans; Intest | 1986 |
Rectal gangrene: a complication of phosphate enema.
Topics: Aged; Constipation; Debridement; Drug Therapy, Combination; Enema; Female; Gangrene; Gentamicins; He | 1986 |
Clinical manifestations of halophilic non-cholera Vibrio infections.
Topics: Aged; Ampicillin; Cephalothin; Clindamycin; Diarrhea; Feces; Foodborne Diseases; Gangrene; Gentamici | 1974 |
Gastroschisis: ten-year review.
Topics: Abdominal Muscles; Cell Differentiation; Female; Gangrene; Gastrointestinal Motility; Gentamicins; H | 1973 |
Tissue antibiotic penetration in streptococcal gangrene.
Topics: Amputation, Surgical; Anti-Bacterial Agents; Cephalothin; Debridement; Gangrene; Gentamicins; Humans | 1973 |
Halophilic vibrios from extraintestinal lesions in man.
Topics: Accidents, Aviation; Adult; Aged; Cephalothin; Erythromycin; Female; Gallbladder Diseases; Gangrene; | 1973 |
Clinicopathologic conference. Disseminated intravascular coagulation.
Topics: Adenocarcinoma; Aged; Atrial Fibrillation; Blood Transfusion; Cephalothin; Digoxin; Disseminated Int | 1973 |
Ecthyma gangrenosum: full thickness nasal slough.
Topics: Carbenicillin; Cartilage; Debridement; Ecthyma; Female; Gangrene; Gentamicins; Humans; Infant, Newbo | 1973 |
Osteomyelitis after exchange transfusion.
Topics: Cloxacillin; Dextrans; Exchange Transfusion, Whole Blood; Female; Gangrene; Gentamicins; Humans; Inf | 1971 |