Page last updated: 2024-10-27

gentamicin and Fungal Diseases

gentamicin has been researched along with Fungal Diseases in 32 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to test the comparative efficacy and toxicity of empiric gentamicin and ciprofloxacin, in combination with piperacillin, in febrile patients with treatment-induced neutropenia."5.08Ciprofloxacin plus piperacillin is an equally effective regimen for empiric therapy in febrile neutropenic patients compared with standard therapy. ( Betts, RF; Blair, EA; Flesher, WR; Griggs, JJ; Norton, JR; Rowe, JM, 1998)
" From the published evidence, the most promising associations are, for staphylococcal infections, gentamicin, erythromycin, kanamycin and fusidic acid."4.76Clinical use of rifampicin in combination for non-mycobacterial infections: a survey of published evidence. ( Fowst, G; Nessi, R, 1979)
" Pimaricin was effective in our patients with Candida infections and in one patient with Aspergillus infection that had been unresponsive to previous amphotericin B."3.65Keratomycosis in Wisconsin. ( Chin, GN; Hyndiuk, RA; Kwasny, GP; Schultz, RO, 1975)
" Whenever a laboratory-derived minimum inhibitory concentration (MIC) was not available to guide dosing decisions, a surrogate target MIC was assumed in 77% of hospitals."1.56Therapeutic drug monitoring of commonly used anti-infective agents: A nationwide cross-sectional survey of Australian hospital practices. ( Alffenaar, JW; Cotta, MO; Daveson, K; Imani, S; Lau, C; Marriott, D; Penm, J; Roberts, JA; Sandaradura, I; Tabah, A; Trethewy, N; van Hal, S; Williams, P, 2020)
"Ciclopirox is a synthetic antimycotic agent available in a variety of formulations to treat superficial fungal infections."1.35Ototoxic effect of topical ciclopirox as an antimycotic preparation. ( Akdaş, F; Baylancicek, S; Ciprut, A; Sari, M; Serin, GM; Tutkun, A, 2008)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199024 (75.00)18.7374
1990's3 (9.38)18.2507
2000's2 (6.25)29.6817
2010's2 (6.25)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Imani, S1
Alffenaar, JW1
Cotta, MO1
Daveson, K1
van Hal, S1
Lau, C1
Marriott, D1
Penm, J1
Roberts, JA1
Tabah, A1
Trethewy, N1
Williams, P1
Sandaradura, I1
Zou, C1
Xu, BY1
Guo, WT1
Mu, WB1
Ji, BC1
Cao, L1
Bhattacharya, S1
Goel, G1
Mukherjee, S1
Bhaumik, J1
Chandy, M1
Baylancicek, S1
Serin, GM1
Ciprut, A1
Sari, M1
Akdaş, F1
Tutkun, A1
Izumi, K1
Hisata, Y1
Hazama, S1
Pizzo, PA1
Robichaud, KJ1
Gill, FA1
Witebsky, FG1
Arnow, PM1
Carandang, GC1
Zabner, R1
Irwin, ME1
Muralidhar, S1
Sulthana, M1
Griggs, JJ1
Blair, EA1
Norton, JR1
Rowe, JM1
Flesher, WR1
Betts, RF1
Chin, GN1
Hyndiuk, RA1
Kwasny, GP1
Schultz, RO1
Forster, RK2
Rebell, G2
Stiles, W1
Hennemann, HH1
Peyman, GA1
Sanders, DR1
Gillett, AP1
Wise, R1
Geddes, AM1
Schimpff, SC1
Nessi, R1
Fowst, G1
Zazgornik, J1
Schmidt, P1
Kopsa, H1
Pils, P1
Balcke, P1
Bagby, GC1
Gunning, JJ1
Wilson, LA1
Fong, LP1
Gladstone, D1
Casey, TA1
Levine, AS1
Graw, RG1
Young, RC1
Bodey, GP1
Rosenbaum, B1
Jones, FR1
Christensen, GR1
Dupuis, F1
Vereerstraeten, P1
van Geertruyden, J1
Kinnaert, P1
Schoutens, E1
Toussaint, C1
Jedrzejczak, WW1
Czarnecki, C1
Levi, JA1
Vincent, PC1
Jennis, F1
Lind, DE1
Gunz, FW1
Klastersky, J1
Weerts, D1
Hensgens, C1
Debusscher, L1
White, JH1
Plotkin, SA1
Mossel, DA1
Kleynen-Semmeling, AM1
Vincentie, HM1
Beerens, H1
Catsaras, M1
Wysocki, S1
Bunn, PA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
ANTIVORIFUNGOL:Strategy of Antifungal Use in Oncohematological Neutropenic Patients. Use of Voriconazole as Early Treatment.[NCT00386802]Phase 4115 participants (Anticipated)Interventional2006-08-31Completed
An Open Intravenous Multiple Dose, Multi-Center Study to Investigate the Pharmacokinetics, Safety and Toleration of Voriconazole in Children Aged 2-12 Years Who Require Treatment for the Prevention of Systemic Fungal Infection[NCT00005912]Phase 148 participants Interventional2000-06-30Completed
Phase I Study of the Safety, Tolerance, and Pharmacokinetics of FK463 in Immunocompromised Children With Fever and Neutropenia[NCT00001790]Phase 1120 participants Interventional1998-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for gentamicin and Fungal Diseases

ArticleYear
Clinical use of rifampicin in combination for non-mycobacterial infections: a survey of published evidence.
    The Journal of international medical research, 1979, Volume: 7, Issue:3

    Topics: Amphotericin B; Cephalosporins; Chloramphenicol; Colistin; Drug Therapy, Combination; Endocarditis,

1979
Management of infections in patients with leukemia and lymphoma: current concepts and experimental approaches.
    Seminars in hematology, 1972, Volume: 9, Issue:2

    Topics: Amphotericin B; Ampicillin; Antifungal Agents; Bacterial Infections; Blood Transfusion; Bone Marrow

1972
[Management of infections in neutropenia].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1974, Nov-01, Volume: 27, Issue:21

    Topics: Agranulocytosis; Bacterial Infections; Carbenicillin; Cross Infection; Gentamicins; Humans; Immunity

1974

Trials

3 trials available for gentamicin and Fungal Diseases

ArticleYear
Randomized controlled trial of selective bowel decontamination for prevention of infections following liver transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:6

    Topics: Ampicillin; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Cefotaxime; Colisti

1996
Ciprofloxacin plus piperacillin is an equally effective regimen for empiric therapy in febrile neutropenic patients compared with standard therapy.
    American journal of hematology, 1998, Volume: 58, Issue:4

    Topics: Adult; Amphotericin B; Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Female; Fever

1998
Therapy of infection in patients with granulocytopenia.
    The Medical clinics of North America, 1977, Volume: 61, Issue:5

    Topics: Agranulocytosis; Amikacin; Anti-Bacterial Agents; Blood Transfusion; Carbenicillin; Cephalothin; Cli

1977

Other Studies

26 other studies available for gentamicin and Fungal Diseases

ArticleYear
Therapeutic drug monitoring of commonly used anti-infective agents: A nationwide cross-sectional survey of Australian hospital practices.
    International journal of antimicrobial agents, 2020, Volume: 56, Issue:6

    Topics: Anti-Infective Agents; Australia; Bacteria; Bacterial Infections; Clinical Decision-Making; Cross-Se

2020
[Efficacy evaluation of one-stage revision combined with intra-articular injection of antifungal agents in the treatment of chronic periprosthetic fungal infection].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2019, May-01, Volume: 57, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Antifungal Agents; Arthroplasty, Replacement; Chronic Disease; Combined

2019
Epidemiology of antimicrobial resistance in an oncology center in eastern India.
    Infection control and hospital epidemiology, 2015, Volume: 36, Issue:7

    Topics: Acinetobacter; Amikacin; Anti-Bacterial Agents; Antifungal Agents; Bacterial Infections; Cancer Care

2015
Ototoxic effect of topical ciclopirox as an antimycotic preparation.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2008, Volume: 29, Issue:7

    Topics: Administration, Topical; Animals; Antifungal Agents; Brain Stem; Ciclopirox; Ear, External; Evoked P

2008
A rare case of infective endocarditis complicated by Trichosporon asahii fungemia treated by surgery.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2009, Volume: 15, Issue:5

    Topics: Anti-Bacterial Agents; Antifungal Agents; Aortic Valve; Combined Modality Therapy; Echocardiography;

2009
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Nigrospora causing corneal ulcer--a case report.
    Indian journal of pathology & microbiology, 1997, Volume: 40, Issue:4

    Topics: Antifungal Agents; Atropine; Cornea; Corneal Diseases; Gentamicins; Humans; Ketoconazole; Male; Mico

1997
Keratomycosis in Wisconsin.
    American journal of ophthalmology, 1975, Volume: 79, Issue:1

    Topics: Acetazolamide; Aged; Agricultural Workers' Diseases; Amphotericin B; Aspergillosis; Atropine; Candid

1975
Recurrent keratitis due to Acremonium potronii.
    American journal of ophthalmology, 1975, Volume: 79, Issue:1

    Topics: Adolescent; Atropine; Bacitracin; Corneal Injuries; Corneal Ulcer; Cyanoacrylates; Eye Injuries; Gen

1975
[Septicaemia in leukaemia (author's transl)].
    Medizinische Klinik, 1977, Apr-15, Volume: 72, Issue:15

    Topics: Adult; Amikacin; Ampicillin; Chloramphenicol; Female; Gentamicins; Humans; Immunity, Cellular; Immun

1977
Management of endophthalmitis.
    Transactions of the Ophthalmological Society of New Zealand, 1977, Volume: 29

    Topics: Amphotericin B; Bacterial Infections; Dexamethasone; Endophthalmitis; Gentamicins; Humans; Injection

1977
Use of antibiotics. Infection in the compromised host.
    British medical journal, 1978, Jul-29, Volume: 2, Issue:6133

    Topics: Amphotericin B; Anti-Bacterial Agents; Carbenicillin; Cephalosporins; Drug Therapy, Combination; Gen

1978
[Mixed infection after renal transplantation (author's transl)].
    Wiener klinische Wochenschrift, 1979, Aug-10, Volume: 91, Issue:15

    Topics: Bacterial Infections; Female; Gentamicins; Humans; Immunosuppression Therapy; Kidney Transplantation

1979
Botryomycosis as an obstructive hepatic disease.
    Archives of internal medicine, 1978, Volume: 138, Issue:3

    Topics: Adult; Gentamicins; Hepatitis; Humans; Lung Diseases; Male; Mitosporic Fungi; Mycoses

1978
Dematiaceous fungal keratitis. Clinical isolates and management.
    The British journal of ophthalmology, 1975, Volume: 59, Issue:7

    Topics: Administration, Topical; Adolescent; Adult; Amphotericin B; Child; Chromoblastomycosis; Corneal Ulce

1975
Corneo-scleral rim cultures: donor contamination a case of fungal endophthalmitis transmitted by K-Sol stored cornea.
    Eye (London, England), 1988, Volume: 2 ( Pt 6)

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Candidiasis; Child; Child, Preschool; Chondroitin Sulfat

1988
Effect of prophylactic measures on the microbial flora of patients in protected environment units.
    Medicine, 1974, Volume: 53, Issue:3

    Topics: Adolescent; Adult; Air Movements; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacteria

1974
Pullularia corneal ulcer.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1974, Volume: 92, Issue:6

    Topics: Administration, Topical; Amphotericin B; Bacitracin; Corneal Injuries; Corneal Ulcer; Eye Injuries;

1974
Salmonella typhimurium urinary infection after kidney transplantation. Report of seven cases.
    Clinical nephrology, 1974, Volume: 2, Issue:4

    Topics: Acetamides; Adolescent; Adult; Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Female; Gentamici

1974
Prophylactic oral antibiotics in the management of acute leukaemia.
    The Medical journal of Australia, 1973, May-26, Volume: 1, Issue:21

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents

1973
Fever of unexplained origin in patients with cancer.
    European journal of cancer, 1973, Volume: 9, Issue:9

    Topics: Bacterial Infections; Carbenicillin; Cephalothin; Endocarditis; Ethambutol; Female; Fever of Unknown

1973
Fungal contamination of donor eyes.
    The British journal of ophthalmology, 1969, Volume: 53, Issue:1

    Topics: Adult; Amphotericin B; Aspergillus; Cornea; Corneal Transplantation; Gentamicins; Humans; Male; Myco

1969
Antibiotics 1971.
    Clinical pediatrics, 1971, Volume: 10, Issue:7

    Topics: Adult; Anti-Bacterial Agents; Antiviral Agents; Catheterization; Cephalosporins; Endocarditis, Bacte

1971
Oxytetracycline-glucose-yeast extract agar for selective enumeration of moulds and yeasts in foods and clinical material.
    The Journal of applied bacteriology, 1970, Volume: 33, Issue:3

    Topics: Agar; Bacillus; Culture Media; Feces; Food Microbiology; Fungi; Gentamicins; Glucose; Humans; Mycose

1970
[Gentamycin in surgery].
    Deutsche medizinische Wochenschrift (1946), 1969, Volume: 94, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Resistance, Microbial; Exanthema; Female; Gen

1969
Present power potions for pestilences and plagues.
    Transactions of the American Clinical and Climatological Association, 1966, Volume: 77

    Topics: Amantadine; Anti-Bacterial Agents; Antiviral Agents; Cephaloridine; Cephalosporins; Gentamicins; Hum

1966