gentamicin has been researched along with Friedreich Disease in 1 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Excerpt | Relevance | Reference |
---|---|---|
"The neurodegeneration observed in Friedreich's ataxia can be well explained on the basis of a mitochondrial iron overload responsible for an increased production of highly toxic free radicals." | 1.30 | Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in mitochondria. ( Cazzalini, O; Foury, F, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Foury, F | 1 |
Cazzalini, O | 1 |
1 other study available for gentamicin and Friedreich Disease
Article | Year |
---|---|
Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in mitochondria.
Topics: Adenosine Triphosphatases; Animals; Cell Division; Cell Respiration; Copper; DNA, Mitochondrial; Fra | 1997 |