Page last updated: 2024-10-27

gentamicin and Fever of Unknown Origin

gentamicin has been researched along with Fever of Unknown Origin in 16 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Fever of Unknown Origin: Fever in which the etiology cannot be ascertained.

Research Excerpts

ExcerptRelevanceReference
"To determine the population pharmacokinetics of gentamicin for patients with febrile neutropenia, with or without sepsis."7.70Population analysis of once-daily dosing of gentamicin in patients with neutropenia. ( Duffull, SB; Peterson, AK, 1998)
"To evaluate efficacy of ampicilline/sulbactame and fluconasole in the regimen of empirical antibiotic therapy in patients with acute leukemia."5.08[The empirical antibiotic therapy of patients with acute leukemias: the results of a multicenter study]. ( Filatov, LB; Iarikova, EN; Isaev, VG; Kaletin, GI; Kaporskaia, TS; Kliasova, GA; Klimko, NN; Lapin, VA; Medvedeva, NV; Parovichnikova, EN; Porokhona, ON; Pristupa, AS; Rekhtman, GB; Rossiev, VA; Savchenko, VG; Sharov, LN; Tolkacheva, TV; Tumakov, VA, 1998)
"To assess the efficacy of single-agent therapy relative to standard combination antibiotic therapy for the initial management of fever and neutropenia in cancer patients, we conducted a randomized trial comparing ceftazidime alone with a combination of cephalothin, gentamicin, and carbenicillin."5.06A randomized trial comparing ceftazidime alone with combination antibiotic therapy in cancer patients with fever and neutropenia. ( Browne, M; Commers, J; Cotton, D; Gress, J; Hathorn, JW; Hiemenz, J; Longo, D; Marshall, D; McKnight, J; Pizzo, PA, 1986)
"Neutropenic cancer patients were given carbenicillin, cephalothin, and gentamicin (CCG) during 51 evaluable episodes of fever of unknown origin."5.04A study of antibiotic therapy in fever of unknown origin in neutropenic cancer patients. ( Björnsson, S; Henderson, ES; Preisler, H, 1977)
"To determine the population pharmacokinetics of gentamicin for patients with febrile neutropenia, with or without sepsis."3.70Population analysis of once-daily dosing of gentamicin in patients with neutropenia. ( Duffull, SB; Peterson, AK, 1998)
"112 patients with primary rectal cancer were enrolled in this study."2.77Local antibiotic therapy in rectal cancer surgery. ( Dziki, A; Kołacińska, A; Morawiec, Z; Pawlak, M, 2012)
"Bacteremia was documented in 14 of 156 previously healthy children with temperatures of at least 40."1.29Acute fevers of unknown origin in young children in the tropics. ( Abiodun, PO; Akpede, GO; Sykes, RM, 1993)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19909 (56.25)18.7374
1990's4 (25.00)18.2507
2000's1 (6.25)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zrig, M1
Mnif, H1
Zrig, A1
Koubaa, M1
Jawahdou, R1
Mnari, W1
Golli, W1
Abid, A1
Morawiec, Z1
Pawlak, M1
Kołacińska, A1
Dziki, A1
Schoen, SP1
Zimmermann, TF1
Boscheri, A1
Schmeisser, A1
Strasser, RH1
Pizzo, PA3
Robichaud, KJ2
Gill, FA2
Witebsky, FG2
Akpede, GO1
Abiodun, PO1
Sykes, RM1
El Bakri, F1
Pallett, A1
Smith, AG1
Duncombe, AS1
Peterson, AK1
Duffull, SB1
Kliasova, GA1
Savchenko, VG1
Parovichnikova, EN1
Isaev, VG1
Tolkacheva, TV1
Rossiev, VA1
Filatov, LB1
Tumakov, VA1
Iarikova, EN1
Rekhtman, GB1
Pristupa, AS1
Medvedeva, NV1
Sharov, LN1
Klimko, NN1
Porokhona, ON1
Lapin, VA1
Kaporskaia, TS1
Kaletin, GI1
Björnsson, S1
Preisler, H1
Henderson, ES1
Levine, AS1
Deisseroth, AB1
Glaubiger, DL1
Maclowry, JD1
Magrath, IT1
Poplack, DG1
Simon, RM1
Feldman, L1
Lamson, M1
Gallelli, JF1
Bennett, JE1
Gurwith, M1
Brunton, JL1
Lank, B1
Ronald, AR1
Harding, GK1
McCullough, DW1
Fink, FM1
Frischhut-Schiffer, EM1
Ausserer, B1
Allerberger, F1
Guggenbichler, JP1
Hathorn, JW1
Hiemenz, J1
Browne, M1
Commers, J1
Cotton, D1
Gress, J1
Longo, D1
Marshall, D1
McKnight, J1
Rodriguez, V1
Burgess, M1
Bodey, GP1
Klastersky, J1
Weerts, D1
Hensgens, C1
Debusscher, L1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
ANTIVORIFUNGOL:Strategy of Antifungal Use in Oncohematological Neutropenic Patients. Use of Voriconazole as Early Treatment.[NCT00386802]Phase 4115 participants (Anticipated)Interventional2006-08-31Completed
An Open Intravenous Multiple Dose, Multi-Center Study to Investigate the Pharmacokinetics, Safety and Toleration of Voriconazole in Children Aged 2-12 Years Who Require Treatment for the Prevention of Systemic Fungal Infection[NCT00005912]Phase 148 participants Interventional2000-06-30Completed
Phase I Study of the Safety, Tolerance, and Pharmacokinetics of FK463 in Immunocompromised Children With Fever and Neutropenia[NCT00001790]Phase 1120 participants Interventional1998-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for gentamicin and Fever of Unknown Origin

ArticleYear
Local antibiotic therapy in rectal cancer surgery.
    Polski przeglad chirurgiczny, 2012, Volume: 84, Issue:12

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Anti-Bacterial Agent

2012
[The empirical antibiotic therapy of patients with acute leukemias: the results of a multicenter study].
    Terapevticheskii arkhiv, 1998, Volume: 70, Issue:7

    Topics: Acute Disease; Adult; Ampicillin; Anti-Bacterial Agents; Cefoperazone; Cephalosporins; Drug Therapy,

1998
A study of antibiotic therapy in fever of unknown origin in neutropenic cancer patients.
    Medical and pediatric oncology, 1977, Volume: 3, Issue:4

    Topics: Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Carbenicillin; Cephalothin; Chloramphenicol; Cl

1977
Duration of empiric antibiotic therapy in granulocytopenic patients with cancer.
    The American journal of medicine, 1979, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Agranulocytosis; Carbenicillin; Cephalothin; Child; Child, Preschool; Clinical Tr

1979
Granulocytopenia in hospitalized patients. II. A prospective comparison of two antibiotic regimens in the empiric therapy of febrile patients.
    The American journal of medicine, 1978, Volume: 64, Issue:1

    Topics: Adolescent; Agranulocytosis; Carbenicillin; Cephalothin; Child; Child, Preschool; Drug Therapy, Comb

1978
A randomized trial comparing ceftazidime alone with combination antibiotic therapy in cancer patients with fever and neutropenia.
    The New England journal of medicine, 1986, Aug-28, Volume: 315, Issue:9

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Carbenicillin

1986

Other Studies

10 other studies available for gentamicin and Fever of Unknown Origin

ArticleYear
[Iliopsoas abscess: a rare complication of pyogenic sacroiliitis in a child].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2010, Volume: 17, Issue:2

    Topics: Anti-Bacterial Agents; Arthritis, Infectious; Child; Combined Modality Therapy; Drainage; Female; Fe

2010
[Bacterial pericarditis].
    Deutsche medizinische Wochenschrift (1946), 2005, Sep-30, Volume: 130, Issue:39

    Topics: Aged; Ceftriaxone; Diagnosis, Differential; Diagnostic Imaging; Dyspnea; Fever of Unknown Origin; Fo

2005
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Acute fevers of unknown origin in young children in the tropics.
    The Journal of pediatrics, 1993, Volume: 122, Issue:1

    Topics: Acute Disease; Age Factors; Ampicillin; Anemia; Bacteremia; Child, Preschool; Cloxacillin; Diagnosis

1993
Ototoxicity induced by once-daily gentamicin.
    Lancet (London, England), 1998, May-09, Volume: 351, Issue:9113

    Topics: Adult; Anti-Bacterial Agents; Drug Administration Schedule; Female; Fever of Unknown Origin; Gentami

1998
Population analysis of once-daily dosing of gentamicin in patients with neutropenia.
    Australian and New Zealand journal of medicine, 1998, Volume: 28, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Admini

1998
Surveillance of nosocomial infections by antibiotic monitoring.
    JAMA, 1979, Jun-29, Volume: 241, Issue:26

    Topics: Anti-Bacterial Agents; Cross Infection; Epidemiologic Methods; Fever of Unknown Origin; Gentamicins;

1979
[Empirical antimicrobial therapy of infection and fever episodes in children and adolescents with neutropenia caused by cytotoxic chemotherapy].
    Padiatrie und Padologie, 1989, Volume: 24, Issue:1

    Topics: Adolescent; Agranulocytosis; Antineoplastic Agents; Cefamandole; Cefotaxime; Child; Child, Preschool

1989
Management of fever of unknown origin in patients with neoplasms and neutropenia.
    Cancer, 1973, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Carbenicillin; Cephalothin; Female;

1973
Fever of unexplained origin in patients with cancer.
    European journal of cancer, 1973, Volume: 9, Issue:9

    Topics: Bacterial Infections; Carbenicillin; Cephalothin; Endocarditis; Ethambutol; Female; Fever of Unknown

1973