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gentamicin and Fetal Membranes, Premature Rupture

gentamicin has been researched along with Fetal Membranes, Premature Rupture in 13 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Fetal Membranes, Premature Rupture: Spontaneous tearing of the membranes surrounding the FETUS any time before the onset of OBSTETRIC LABOR. Preterm PROM is membrane rupture before 37 weeks of GESTATION.

Research Excerpts

ExcerptRelevanceReference
"To assess whether daily gentamicin is as effective as 8-hour gentamicin for the treatment of intrapartum chorioamnionitis."9.14Daily compared with 8-hour gentamicin for the treatment of intrapartum chorioamnionitis: a randomized controlled trial. ( Benitz, W; Caughey, AB; El-Sayed, YY; Fuh, K; Lyell, DJ; Pullen, K; Zamah, AM, 2010)
"To assess whether daily gentamicin is as effective as 8-hour gentamicin for the treatment of intrapartum chorioamnionitis."5.14Daily compared with 8-hour gentamicin for the treatment of intrapartum chorioamnionitis: a randomized controlled trial. ( Benitz, W; Caughey, AB; El-Sayed, YY; Fuh, K; Lyell, DJ; Pullen, K; Zamah, AM, 2010)
" We report a case of chorioamnionitis in a triplet pregnancy after midtrimester genetic amniocentesis, in which multiple antibiotic treatment (ampicillin 2 g i."3.70Successful outcome after antibiotic treatment of postamniocentesis membrane rupture and chorioamnionitis in multiple pregnancy. ( Doria, V; Ghidini, A; Kirn, V; Korker, V, 1999)
"The serum half-life of gentamicin following an intravenous dose was compared between 19 pregnant women (28-34 weeks of pregnancy) with premature rupture of the membranes and 17 non-pregnant women with pelvic inflammatory disease, the groups being age and weight matched."3.67Gentamicin serum half-life: a comparison between pregnant and non-pregnant women. ( Amoday, I; Aviram, A; Hezroni, Y; Lazebnik, N; Lazebnik, R; Noy, S, 1985)
"Histological chorioamnionitis was based on the observation of polymorphonuclear leukocyte infiltration of the chorionic plate or the extraplacental fetal membranes."2.70Antibiotic administration in patients with preterm premature rupture of membranes reduces the rate of histological chorioamnionitis: a prospective, randomized, controlled study. ( Gómez, R; Kakarieka, E; Leyton, H; Martínez, MA; Ovalle, A; Rubio, R; Valderrama, O, 2002)
"Treatment with erythromycin, ampicillin, gentamicin, and clindamycin was instituted for a period of 6 days."1.28Eradication of Ureaplasma urealyticum from the amniotic fluid with transplacental antibiotic treatment. ( Hagay, Z; Mazor, M; Nores, J; Romero, R; Sepulveda, W, 1992)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's5 (38.46)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Olita'a, D1
Barnabas, R1
Vali Boma, G1
Pameh, W1
Vince, J1
Duke, T1
Wolf, MF1
Miron, D1
Peleg, D1
Rechnitzer, H1
Portnov, I1
Salim, R1
Keness, Y1
Reich, D1
Ami, MB1
Peretz, A1
Koshnir, A1
Shachar, IB1
Lyell, DJ1
Pullen, K1
Fuh, K1
Zamah, AM1
Caughey, AB1
Benitz, W1
El-Sayed, YY1
Ovalle, A1
Martínez, MA1
Kakarieka, E1
Gómez, R2
Rubio, R1
Valderrama, O1
Leyton, H1
Saleh, FM1
Abb-Gawad, AH1
el-Gazaierly, S1
Arafa, AM1
el-Ghazzawi, E1
Mondión, M1
Vargas, JE1
González, F1
D'Apremont, I1
Rojas, I1
Ghidini, A1
Doria, V1
Kirn, V1
Korker, V1
Cisse, CT1
Mbengue-Diop, R1
Moubarek, M1
Ndiaye, O1
Dotou, CR1
Boye, CS1
Kuakuvi, NK1
Diadhiou, F1
Wong, GP1
Cimolai, N1
Dimmick, JE1
Martin, TR1
Romero, R1
Hagay, Z1
Nores, J1
Sepulveda, W1
Mazor, M1
Kohelet, D1
Usher, M1
Arbel, E1
Arlazoroff, A1
Goldberg, M1
Walss Rodríguez, RJ1
Navarro Castañon, J1
Lazebnik, N1
Noy, S1
Lazebnik, R1
Hezroni, Y1
Amoday, I1
Aviram, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Two Antibiotic Prophylactic Protocols in Preterm Premature Rupture of the Membranes. A Randomized Prospective, Open Trial[NCT02819570]Phase 4400 participants (Anticipated)Interventional2015-11-30Recruiting
Comparison of Once Daily Versus 8 Hour Dosing of Gentamicin for the Treatment of Intrapartum Chorioamnionitis[NCT00185991]126 participants (Anticipated)Interventional2004-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for gentamicin and Fetal Membranes, Premature Rupture

ArticleYear
Pasteurella multocida chorioamnionitis from vaginal transmission.
    Acta obstetricia et gynecologica Scandinavica, 1992, Volume: 71, Issue:5

    Topics: Adult; Ampicillin; Chorioamnionitis; Escherichia coli Infections; Female; Fetal Death; Fetal Membran

1992

Trials

3 trials available for gentamicin and Fetal Membranes, Premature Rupture

ArticleYear
Daily compared with 8-hour gentamicin for the treatment of intrapartum chorioamnionitis: a randomized controlled trial.
    Obstetrics and gynecology, 2010, Volume: 115, Issue:2 Pt 1

    Topics: Adult; Anti-Bacterial Agents; Chorioamnionitis; Double-Blind Method; Drug Administration Schedule; F

2010
Antibiotic administration in patients with preterm premature rupture of membranes reduces the rate of histological chorioamnionitis: a prospective, randomized, controlled study.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2002, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Antibiotic Prophylaxis; Chorioamnionitis; Clindamycin; Drug Therapy, Combination;

2002
[Prophylactic antibiotics in premature rupture of the membranes].
    Ginecologia y obstetricia de Mexico, 1988, Volume: 56

    Topics: Adolescent; Adult; Female; Fetal Membranes, Premature Rupture; Gentamicins; Humans; Penicillins; Pre

1988

Other Studies

9 other studies available for gentamicin and Fetal Membranes, Premature Rupture

ArticleYear
Simplified management protocol for term neonates after prolonged rupture of membranes in a setting with high rates of neonatal sepsis and mortality: a quality improvement study.
    Archives of disease in childhood, 2019, Volume: 104, Issue:2

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Antibiotic Prophylaxis; Clinical Protocols; Developing Co

2019
Reconsidering the Current Preterm Premature Rupture of Membranes Antibiotic Prophylactic Protocol.
    American journal of perinatology, 2015, Volume: 32, Issue:13

    Topics: Amnion; Amoxicillin; Ampicillin; Anti-Bacterial Agents; Chorioamnionitis; Clindamycin; Clinical Prot

2015
Bacteriological examination in cases of premature rupture of membranes.
    Asia-Oceania journal of obstetrics and gynaecology, 1983, Volume: 9, Issue:4

    Topics: Escherichia coli; Female; Fetal Membranes, Premature Rupture; Gentamicins; Humans; Infant, Newborn;

1983
[Premature rupture of fetal membranes in the midtrimester (II): Antibiotic treatment in a case of intraamniotic infection prior to fetal viability].
    Revista chilena de obstetricia y ginecologia, 1994, Volume: 59, Issue:4

    Topics: Adult; Amniotic Fluid; Female; Fetal Membranes, Premature Rupture; Fetal Viability; Gentamicins; Ges

1994
Successful outcome after antibiotic treatment of postamniocentesis membrane rupture and chorioamnionitis in multiple pregnancy.
    American journal of perinatology, 1999, Volume: 16, Issue:8

    Topics: Adult; Amniocentesis; Ampicillin; Anti-Inflammatory Agents; Betamethasone; Chorioamnionitis; Clindam

1999
[Neonatal bacterial infections at the CUH of Dakar].
    Gynecologie, obstetrique & fertilite, 2001, Volume: 29, Issue:6

    Topics: Anti-Bacterial Agents; Bacterial Infections; Drug Resistance, Microbial; Enterobacter; Enterococcus;

2001
Eradication of Ureaplasma urealyticum from the amniotic fluid with transplacental antibiotic treatment.
    American journal of obstetrics and gynecology, 1992, Volume: 166, Issue:2

    Topics: Adult; Amniotic Fluid; Ampicillin; Chorioamnionitis; Clindamycin; Drug Therapy, Combination; Erythro

1992
Effect of gentamicin on the auditory brainstem evoked response in term infants: a preliminary report.
    Pediatric research, 1990, Volume: 28, Issue:3

    Topics: Bacterial Infections; Evoked Potentials, Auditory, Brain Stem; Female; Fetal Membranes, Premature Ru

1990
Gentamicin serum half-life: a comparison between pregnant and non-pregnant women.
    Postgraduate medical journal, 1985, Volume: 61, Issue:721

    Topics: Adult; Creatinine; Female; Fetal Membranes, Premature Rupture; Gentamicins; Half-Life; Humans; Pelvi

1985