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gentamicin and Experimental Pneumococcal Meningitis

gentamicin has been researched along with Experimental Pneumococcal Meningitis in 17 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
"The influence of methylprednisolone on the passage of ampicillin and gentamicin into and activity within cerebrospinal fluid was examined in two models of experimental meningitis."7.66Effect of methylprednisolone on entry of ampicillin and gentamicin into cerebrospinal fluid in experimental pneumococcal and Escherichia coli meningitis. ( Brodeur, JP; Scheld, WM, 1983)
"Forty-five children (aged 1 day to 15 years) with bacterial meningitis were randomized to receive either traditional therapy (ampicillin and chloramphenicol or gentamicin, pending sensitivity) or ceftriaxone (100 mg/kg per day in two doses for a minimum of 10 days)."5.05Comparison of ceftriaxone and traditional therapy of bacterial meningitis. ( Congeni, BL, 1984)
"The influence of methylprednisolone on the passage of ampicillin and gentamicin into and activity within cerebrospinal fluid was examined in two models of experimental meningitis."3.66Effect of methylprednisolone on entry of ampicillin and gentamicin into cerebrospinal fluid in experimental pneumococcal and Escherichia coli meningitis. ( Brodeur, JP; Scheld, WM, 1983)
" Although the use of steroids as adjunctive therapy for bacterial meningitis has been found to be beneficial, the dosage of dexamethasone administered in our cases may not be enough to suppress the synthesis and release of the cytokines."1.29[Two cases of severe bacterial meningitis with paranasal sinusitis followed by cerebrovascular disease--pathophysiology and treatment of cerebrovascular disease]. ( Matsukura, S; Miyazato, M; Nagata, N; Ohi, T; Sugimoto, S, 1996)
" References to indication and dosage of several chemotherapeutics are given on the basis of recent knowledge of liquor metabolism as well as clinical and experimental findings."1.27[Acute bacterial meningitis in adults--a therapeutic problem]. ( Bernasowski, A; Kunze, M, 1986)
"Scan findings included hydrocephalus, cerebritis, vasculitis, subdural effusion, cerebral atrophy, abscess, and ependymitis."1.26Computed tomography in purulent meningitis. ( Bodino, J; Del Valle, M; Leiguarda, R; López, EL; Lylyk, P; Monges, J; Wasserman, JP, 1982)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199012 (70.59)18.7374
1990's4 (23.53)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Congeni, BL1
Scheld, WM1
Brodeur, JP1
Bodino, J1
Lylyk, P1
Del Valle, M1
Wasserman, JP1
Leiguarda, R1
Monges, J1
López, EL1
Margaliot, S1
Reichert, N1
Rubinstein, E1
Raymond, J1
Bingen, E1
Doit, C1
Brahimi, N1
Bergeret, M1
Badoual, J1
Gendrel, D1
Le Masne, A1
Gaillard, JL1
Lacaille, F1
Pron, B1
Labenne, M1
Silly, C1
Chéron, G1
Miyazato, M1
Ohi, T1
Sugimoto, S1
Nagata, N1
Matsukura, S1
Verghote, M1
Questiaux, JF1
Kummert, J1
Puissant, B1
Evrard, J1
Cottagnoud, P1
Gerber, CM1
Cottagnoud, M1
Täuber, MG1
Sicilia, T1
Fadon, A1
Rodríguez, A1
Soto, J1
Hambleton, G1
Davies, PA1
Bernasowski, A1
Kunze, M1
Mortier, W1
McDonald, R1
Klastersky, J1
Brihaye, J1
Yow, MD1
Baker, CJ1
Barrett, FF1
Ortigoza, CO1

Reviews

2 reviews available for gentamicin and Experimental Pneumococcal Meningitis

ArticleYear
Bacterial meningitis. Some aspects of diagnosis and treatment.
    Archives of disease in childhood, 1975, Volume: 50, Issue:9

    Topics: Ampicillin; Bacterial Infections; Brain Edema; Child, Preschool; Chloramphenicol; Cloxacillin; Genta

1975
[Treatment of central nervous system infections].
    Bruxelles medical, 1973, Volume: 53, Issue:5

    Topics: Adult; Aminosalicylic Acids; Ampicillin; Anti-Bacterial Agents; Bacteria; Brain Abscess; Chloramphen

1973

Trials

1 trial available for gentamicin and Experimental Pneumococcal Meningitis

ArticleYear
Comparison of ceftriaxone and traditional therapy of bacterial meningitis.
    Antimicrobial agents and chemotherapy, 1984, Volume: 25, Issue:1

    Topics: Adolescent; Ampicillin; Cefotaxime; Ceftriaxone; Child; Child, Preschool; Chloramphenicol; Female; G

1984

Other Studies

14 other studies available for gentamicin and Experimental Pneumococcal Meningitis

ArticleYear
Effect of methylprednisolone on entry of ampicillin and gentamicin into cerebrospinal fluid in experimental pneumococcal and Escherichia coli meningitis.
    Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:1

    Topics: Ampicillin; Animals; Drug Interactions; Escherichia coli Infections; Gentamicins; Meningitis; Mening

1983
Computed tomography in purulent meningitis.
    American journal of diseases of children (1960), 1982, Volume: 136, Issue:6

    Topics: Brain Edema; Cerebral Ventriculography; Child; Child, Preschool; Female; Gentamicins; Humans; Hydroc

1982
[Fatal infection with chloramphenicol resistant pneumococcus].
    Harefuah, 1982, Mar-01, Volume: 102, Issue:5

    Topics: Aged; Chloramphenicol; Cross Infection; Drug Resistance, Microbial; Gentamicins; Humans; Male; Menin

1982
Failure of cefotaxime treatment in a patient with penicillin-resistant pneumococcal meningitis and confirmation of nosocomial spread by random amplified polymorphic DNA analysis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:1

    Topics: Base Sequence; Cefotaxime; Cephalosporins; Cross Infection; DNA Primers; DNA, Bacterial; Drug Therap

1995
[Pneumococcal meningitis in children: should probabilistic antibiotherapy of infectious meningitis be modified?].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1996, Volume: 3, Issue:5

    Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Drug Therapy, Combination;

1996
[Two cases of severe bacterial meningitis with paranasal sinusitis followed by cerebrovascular disease--pathophysiology and treatment of cerebrovascular disease].
    Rinsho shinkeigaku = Clinical neurology, 1996, Volume: 36, Issue:9

    Topics: Adult; Ampicillin; Anti-Bacterial Agents; Cerebrovascular Disorders; Dexamethasone; Drug Therapy, Co

1996
[Neonatal type 1 pneumococcal meningitis and maternal septicemia].
    Revue medicale de Liege, 1998, Volume: 53, Issue:6

    Topics: Ampicillin; Female; Gentamicins; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical;

1998
Gentamicin increases the efficacy of vancomycin against penicillin-resistant pneumococci in the rabbit meningitis model.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; G

2002
Fosfomycin in pneumococcal meningitis.
    Chemotherapy, 1977, Volume: 23 Suppl 1

    Topics: Adult; Ampicillin; Cerebrospinal Fluid; Child; Drug Interactions; Drug Therapy, Combination; Female;

1977
Intrathecal antibiotics in purulent meningitis.
    Lancet (London, England), 1976, Nov-13, Volume: 2, Issue:7994

    Topics: Gentamicins; Humans; Infant, Newborn; Infant, Newborn, Diseases; Injections, Spinal; Meningitis, Pne

1976
[Acute bacterial meningitis in adults--a therapeutic problem].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1986, Jan-01, Volume: 41, Issue:1

    Topics: Adult; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Blood-Brain Barrier; Cephalosporins;

1986
[Chemotherapy of purulent meningitis].
    Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:5

    Topics: Adolescent; Ampicillin; Carbenicillin; Child; Child, Preschool; Chloramphenicol; Drug Synergism; Gen

1970
Purulent meningitis in newborn babies: observations and comments based on a series of 82 patients.
    Clinical pediatrics, 1972, Volume: 11, Issue:8

    Topics: Black People; Cerebral Ventricles; Escherichia coli; Female; Gentamicins; Humans; Hydrocephalus; Inf

1972
Initial antibiotic management of bacterial meningitis (selection in relationship to age).
    Medicine, 1973, Volume: 52, Issue:4

    Topics: Adolescent; Age Factors; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Cerebrospinal Flui

1973