gentamicin has been researched along with Endolymphatic Hydrops in 19 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Endolymphatic Hydrops: An accumulation of ENDOLYMPH in the inner ear (LABYRINTH) leading to buildup of pressure and distortion of intralabyrinthine structures, such as COCHLEA and SEMICIRCULAR CANALS. It is characterized by SENSORINEURAL HEARING LOSS; TINNITUS; and sometimes VERTIGO.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Perilymph gentamicin concentrations and correlation with endolymphatic hydrops in an animal model were assessed." | 7.88 | Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter? ( Duan, M; Marques, P; Perez-Fernandez, N; Spratley, J, 2018) |
| "To verify the hypothesis that intratympanic (IT) gentamicin (Gent) treatment in Ménière's disease (MD) is capable of reducing endolymphatic hydrops (EH), as evaluated by 3-dimensional fluid-attenuated inversion recovery (3D-FLAIR) sequence in a 3-Tesla magnetic resonance imaging (MRI) unit, after IT gadolinium administration." | 7.78 | Magnetic resonance imaging fails to show evidence of reduced endolymphatic hydrops in gentamicin treatment of Ménière's disease. ( Barbieri, F; Beltramello, A; Fiorino, F; Pizzini, FB, 2012) |
| " Special attention should be paid to the role of dietary restrictions for glucose in patients with Meniere's disease, as there is a strong evidence about the presence of insulin receptors in the saccule, the main structure affected by pathological changes due to endolymphatic hydrops; to the possible use of endogenous antisecretory factor administered in specially processed cereals; and to the effects of low-dose intratympanic gentamicin, especially in patients with intractable Meniere's disease." | 3.96 | Letter to Editor concerning the "Therapeutic strategies in the treatment of Meniere's disease: the Italian Experience". ( Cassandro, C; Cassandro, E; De Luca, P; Gioacchini, FM; Ralli, M; Savignano, L; Scarpa, A, 2020) |
| "The aims of the present study are to investigate the variations in clinical features, including medical history, hearing function, vestibular function, and degree of endolymphatic hydrops (EH), in Meniere's disease (MD) patients with and without drop attacks (DAs), and to examine the efficacy of intratympanic gentamicin (ITG) treatment in alleviating DAs." | 3.91 | Clinical features and management of Meniere's disease patients with drop attacks. ( Dai, C; Li, X; Sha, Y; Wu, Q, 2019) |
| "Perilymph gentamicin concentrations and correlation with endolymphatic hydrops in an animal model were assessed." | 3.88 | Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter? ( Duan, M; Marques, P; Perez-Fernandez, N; Spratley, J, 2018) |
| " Further repeated ITD courses or intratympanic gentamicin (ITG) were given if the vertigo was not satisfactorily controlled." | 3.83 | Intratympanic steroids injection is effective for the treatment of drop attacks with Ménière's disease and delayed endolymphatic hydrops: A retrospective study. ( Kong, WJ; Leng, Y; Liu, B; Liu, D; Liu, J; Zhang, SL; Zhou, R, 2016) |
| "1) To evaluate the efficacy of, and problems with, intratympanic gentamicin injection (ITG) in medically intractable definite Ménière's disease (MD) and secondary endolymphatic hydrops (EH); and 2) to review the vestibular status and treatment options of intractable vertigo even after ITG." | 3.81 | Management of intractable Ménière's disease after intratympanic injection of gentamicin. ( Choi, BY; Han, JJ; Koo, JW; Park, J; Rah, YC, 2015) |
| " Moreover, intratympanic gentamicin injection (ITG), as a chemical labyrinthectomy, is a simple alternative for controlling vertigo in patients with ipsilateral DEH." | 3.81 | Intratympanic injection in delayed endolymphatic hydrops. ( Kong, W; Leng, Y; Liu, B; Liu, J; Zhang, S; Zhou, R, 2015) |
| "To verify the hypothesis that intratympanic (IT) gentamicin (Gent) treatment in Ménière's disease (MD) is capable of reducing endolymphatic hydrops (EH), as evaluated by 3-dimensional fluid-attenuated inversion recovery (3D-FLAIR) sequence in a 3-Tesla magnetic resonance imaging (MRI) unit, after IT gadolinium administration." | 3.78 | Magnetic resonance imaging fails to show evidence of reduced endolymphatic hydrops in gentamicin treatment of Ménière's disease. ( Barbieri, F; Beltramello, A; Fiorino, F; Pizzini, FB, 2012) |
| "Interval treatment with up to three intratympanic gentamicin injections once weekly effectively controlled vertigo while preserving hearing in patients with Ménière's disease and recurrent or resistant vertigo after saccotomy." | 3.73 | Intratympanic gentamicin treatment after endolymphatic sac surgery. ( Gouveris, H; Lange, G; Mann, WJ, 2005) |
| "Diagnosis criteria of Meniere's disease are classified into Meniere's disease with typical cochlear and vestibular symptoms, and atypical Meniere's disease with either cochlear symptoms or vestibular symptoms." | 2.72 | Diagnostic and therapeutic strategies for Meniere's disease of the Japan Society for Equilibrium Research. ( Iwasaki, S; Kitahara, T; Murofushi, T; Origasa, H; Seo, T; Shojaku, H; Suzuki, M; Takeda, N; Watanabe, Y, 2021) |
| "Endolymphatic hydrops is usually diagnosed on the basis of clinical symptoms although objective parameters for this disease can be difficult to differentiate from other disorders of the inner ear." | 1.29 | [Animal experiment studies using a low-frequency, phase-delayed masker in inner ear diagnosis]. ( Höhmann, D, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 8 (42.11) | 24.3611 |
| 2020's | 4 (21.05) | 2.80 |
| Authors | Studies |
|---|---|
| Scarpa, A | 1 |
| Ralli, M | 1 |
| De Luca, P | 1 |
| Savignano, L | 1 |
| Gioacchini, FM | 1 |
| Cassandro, E | 1 |
| Cassandro, C | 1 |
| Liu, Y | 1 |
| Yang, J | 1 |
| Duan, M | 2 |
| Iwasaki, S | 1 |
| Shojaku, H | 1 |
| Murofushi, T | 1 |
| Seo, T | 1 |
| Kitahara, T | 1 |
| Origasa, H | 1 |
| Watanabe, Y | 1 |
| Suzuki, M | 1 |
| Takeda, N | 1 |
| Zhang, D | 1 |
| Lv, Y | 1 |
| Li, X | 2 |
| Li, Y | 1 |
| Song, Y | 1 |
| Fan, Z | 1 |
| Wang, H | 1 |
| Reynard, P | 1 |
| Karkas, A | 1 |
| Gavid, M | 1 |
| Lelonge, Y | 1 |
| Bertholon, P | 1 |
| Marques, P | 1 |
| Perez-Fernandez, N | 1 |
| Spratley, J | 1 |
| Wu, Q | 1 |
| Sha, Y | 1 |
| Dai, C | 1 |
| Rah, YC | 1 |
| Han, JJ | 1 |
| Park, J | 1 |
| Choi, BY | 1 |
| Koo, JW | 1 |
| Liu, B | 2 |
| Zhang, S | 1 |
| Leng, Y | 2 |
| Zhou, R | 2 |
| Liu, J | 2 |
| Kong, W | 1 |
| Liu, D | 1 |
| Zhang, SL | 1 |
| Kong, WJ | 1 |
| Claes, G | 1 |
| Van den Hauwe, L | 1 |
| Wuyts, F | 1 |
| Van de Heyning, P | 1 |
| Fiorino, F | 1 |
| Pizzini, FB | 1 |
| Barbieri, F | 1 |
| Beltramello, A | 1 |
| Sala, T | 2 |
| Minor, LB | 1 |
| Schessel, DA | 1 |
| Carey, JP | 1 |
| Gouveris, H | 1 |
| Lange, G | 1 |
| Mann, WJ | 1 |
| Trine, MB | 1 |
| Lynn, SG | 1 |
| Facer, GW | 1 |
| Kasperbauer, JL | 1 |
| Höhmann, D | 1 |
| Xu, X | 1 |
| Fu, G | 1 |
| Tan, Z | 1 |
3 reviews available for gentamicin and Endolymphatic Hydrops
| Article | Year |
|---|---|
Current status on researches of Meniere's disease: a review.
Topics: Adrenal Cortex Hormones; Betahistine; Endolymphatic Hydrops; Endolymphatic Sac; Gentamicins; Humans; | 2020 |
Diagnostic and therapeutic strategies for Meniere's disease of the Japan Society for Equilibrium Research.
Topics: Anti-Bacterial Agents; Audiometry; Endolymphatic Hydrops; Endolymphatic Sac; Gentamicins; Healthy Li | 2021 |
Ménière's disease.
Topics: Combined Modality Therapy; Diet, Sodium-Restricted; Diuretics; Ear, Middle; Electronystagmography; E | 2004 |
1 trial available for gentamicin and Endolymphatic Hydrops
| Article | Year |
|---|---|
Menière's disease and gentamicin: preliminary results using the minimum effective dose and integrated therapy.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Endol | 2003 |
15 other studies available for gentamicin and Endolymphatic Hydrops
| Article | Year |
|---|---|
Letter to Editor concerning the "Therapeutic strategies in the treatment of Meniere's disease: the Italian Experience".
Topics: Endolymphatic Hydrops; Gentamicins; Humans; Italy; Meniere Disease; Saccule and Utricle | 2020 |
Long-term efficacy of triple semicircular canal plugging in the treatment of patients with ipsilateral delayed endolymphatic hydrops.
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Complementary Therapies; Endolymphatic Hydrops; Female | 2021 |
Delayed endolymphatic hydrops. Special emphasis on nystagmus associated with episodes and contribution of chemical labyrinthectomy.
Topics: Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Deafness; Endolymphatic Hydrops; Female; Gentamic | 2018 |
Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter?
Topics: Animals; Auditory Threshold; Contrast Media; Disease Models, Animal; Ear, Inner; Ear, Middle; Endoly | 2018 |
Clinical features and management of Meniere's disease patients with drop attacks.
Topics: Adult; Case-Control Studies; Endolymphatic Hydrops; Female; Gentamicins; Hearing; Hearing Loss; Hear | 2019 |
Management of intractable Ménière's disease after intratympanic injection of gentamicin.
Topics: Adult; Aged; Cohort Studies; Endolymphatic Hydrops; Female; Follow-Up Studies; Gentamicins; Hearing | 2015 |
Intratympanic injection in delayed endolymphatic hydrops.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Audiometry; Dexamethasone; Dose-Response Relationship, Dru | 2015 |
Intratympanic steroids injection is effective for the treatment of drop attacks with Ménière's disease and delayed endolymphatic hydrops: A retrospective study.
Topics: Adult; Anti-Bacterial Agents; Dexamethasone; Drug Therapy, Combination; Endolymphatic Hydrops; Femal | 2016 |
Does intratympanic gadolinium injection predict efficacy of gentamicin partial chemolabyrinthectomy in Menière's disease patients?
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Evoked Response; Contrast Media; Ear, Inner; Ear, Mi | 2012 |
Magnetic resonance imaging fails to show evidence of reduced endolymphatic hydrops in gentamicin treatment of Ménière's disease.
Topics: Adult; Aged; Ear, Inner; Endolymphatic Hydrops; Female; Gentamicins; Humans; Image Processing, Compu | 2012 |
Intratympanic gentamicin treatment after endolymphatic sac surgery.
Topics: Adult; Aged; Audiometry, Pure-Tone; Auditory Threshold; Ear, Middle; Electronystagmography; Endolymp | 2005 |
Intratympanic gentamicin treatment: preliminary results in two patients with Menière's disease.
Topics: Audiometry, Pure-Tone; Auditory Threshold; Endolymphatic Hydrops; Gentamicins; Hearing Loss, Sensori | 1995 |
[Animal experiment studies using a low-frequency, phase-delayed masker in inner ear diagnosis].
Topics: Animals; Audiometry, Evoked Response; Auditory Threshold; Cochlea; Cochlear Microphonic Potentials; | 1993 |
[The damped torsion swing test in guinea pigs].
Topics: Animals; Electronystagmography; Endolymphatic Hydrops; Female; Gentamicins; Guinea Pigs; Hair Cells, | 1995 |
Transtympanic gentamicin in the treatment of Meniére's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Endolymphatic Hydrops; Follow-Up Studies; Gentamicins; Humans; M | 1997 |