Page last updated: 2024-10-27

gentamicin and Dizziness

gentamicin has been researched along with Dizziness in 9 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Dizziness: An imprecise term which may refer to a sense of spatial disorientation, motion of the environment, or lightheadedness.

Research Excerpts

ExcerptRelevanceReference
"To assess long-term vertigo symptom control in patients after intratympanic gentamicin instillation for incapacitating unilateral Ménière's disease."7.74Long-term vertigo control in patients after intratympanic gentamicin instillation for Ménière's disease. ( Alexander, A; Bodmer, D; Chen, JM; Morong, S; Nedzelski, JM; Stewart, C, 2007)
"Intratympanic gentamicin is used to control dizziness of Ménière's disease, with a low rate of morbidity and a high success rate."7.70Low-dose intratympanic gentamicin treatment for dizziness in Ménière's disease. ( Longridge, NS; Mallinson, AI, 2000)
"A 79-year-old male, with bilateral loss of vestibular function caused by gentamicin toxicity after surgery for prosthetic valve endocarditis, complained of dizziness, difficulty in walking and an increased risk of falling."3.80Treatment of vertigo and postural instability using visual illusions. ( De Ru, JA; Mert, A; van Kerckhoven, G, 2014)
"In Ménière's disease (MD), when patients have incapacitating vertigo that is resistant to drug treatment, an intratympanic gentamicin application (ITG) is often proposed."3.75Tenotomy of the tensor tympani and stapedius tendons in Ménière's disease. ( De Valck, CF; Van de Heyning, PH; Van Rompaey, V; Wuyts, EL, 2009)
"To assess long-term vertigo symptom control in patients after intratympanic gentamicin instillation for incapacitating unilateral Ménière's disease."3.74Long-term vertigo control in patients after intratympanic gentamicin instillation for Ménière's disease. ( Alexander, A; Bodmer, D; Chen, JM; Morong, S; Nedzelski, JM; Stewart, C, 2007)
"Intratympanic gentamicin is used to control dizziness of Ménière's disease, with a low rate of morbidity and a high success rate."3.70Low-dose intratympanic gentamicin treatment for dizziness in Ménière's disease. ( Longridge, NS; Mallinson, AI, 2000)
"Five patients with Menière's disease and disabling vertigo were treated with two intratympanic instillations of gentamicin given at an interval of about 12 h."3.68Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy. ( Magnusson, M; Padoan, S, 1991)
"Surgical management of Meniere's disease is a safe and viable option for patients with medically refractory disease."1.33Surgical management of Meniere's disease in the era of gentamicin. ( Gardner, EK; Jackson, CG; Kaylie, DM, 2005)
"Current data indicate that once-daily aminoglycoside therapy is as efficacious as traditional multiple daily dosing and equally or less toxic."1.29Once-daily aminoglycoside therapy: potential ototoxicity. ( Krieff, D; Singer, C; Smith, C, 1996)
"Netilmicin was administered intramuscularly in a dose of 2 mg/kg body weight every 8 hours."1.26Netilmicin therapy of patients with septicaemia and other severe infections. ( Brandenhoff, P; Bretlau, P; Gammelgaard, PA; Jensen, SH; Rasmussen, F; Stafanger, G; Thomsen, VF, 1980)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's2 (22.22)18.2507
2000's4 (44.44)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Kerckhoven, G1
Mert, A1
De Ru, JA1
De Valck, CF1
Van Rompaey, V1
Wuyts, EL1
Van de Heyning, PH1
Kaylie, DM1
Jackson, CG1
Gardner, EK1
Bodmer, D1
Morong, S1
Stewart, C1
Alexander, A1
Chen, JM1
Nedzelski, JM1
Brandenhoff, P1
Stafanger, G1
Gammelgaard, PA1
Rasmussen, F1
Jensen, SH1
Bretlau, P1
Thomsen, VF1
Singer, C1
Smith, C1
Krieff, D1
Longridge, NS1
Mallinson, AI1
Magnusson, M1
Padoan, S1
Tamai, IY1
Sayers, JF1
Mooradian, AD1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Gentamicin Treatment Prior to Vestibular Schwannoma Surgery in Patients With Definite Remaining Vestibular Function[NCT02379754]Phase 40 participants (Actual)Interventional2015-01-31Withdrawn
Gentamicin Treatment Prior to Vestibular Schwannoma Surgery in Patients With no Measurable Remaining Vestibular Function[NCT02415257]Phase 40 participants (Actual)Interventional2015-04-30Withdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for gentamicin and Dizziness

ArticleYear
Treatment of vertigo and postural instability using visual illusions.
    The Journal of laryngology and otology, 2014, Volume: 128, Issue:11

    Topics: Aged; Dizziness; Gentamicins; Humans; Illusions; Male; Postural Balance; Treatment Outcome; Vertigo;

2014
Tenotomy of the tensor tympani and stapedius tendons in Ménière's disease.
    B-ENT, 2009, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Dizziness; Ear, Middle; Female; Gentamicins; Humans;

2009
Surgical management of Meniere's disease in the era of gentamicin.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2005, Volume: 132, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Audiometry, Pure-Tone; Dizziness; Female; Gentamicins; H

2005
Long-term vertigo control in patients after intratympanic gentamicin instillation for Ménière's disease.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2007, Volume: 28, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Caloric Tests; Dizziness; Drug Implants; Ear, Middle; Electronystagmog

2007
Netilmicin therapy of patients with septicaemia and other severe infections.
    Scandinavian journal of infectious diseases. Supplementum, 1980, Volume: Suppl 23

    Topics: Adult; Aged; Creatinine; Dizziness; Drug Evaluation; Female; Gentamicins; Hearing Loss; Humans; Male

1980
Once-daily aminoglycoside therapy: potential ototoxicity.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:9

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Dizziness; Ear Diseases; Female; Gentamicins; Humans

1996
Low-dose intratympanic gentamicin treatment for dizziness in Ménière's disease.
    The Journal of otolaryngology, 2000, Volume: 29, Issue:1

    Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Dizziness; Ear, Middle; Female; Follow-

2000
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
    Acta oto-laryngologica, 1991, Volume: 111, Issue:4

    Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease;

1991
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
    Acta oto-laryngologica, 1991, Volume: 111, Issue:4

    Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease;

1991
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
    Acta oto-laryngologica, 1991, Volume: 111, Issue:4

    Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease;

1991
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
    Acta oto-laryngologica, 1991, Volume: 111, Issue:4

    Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease;

1991
Aminoglycoside therapy and toxicity in the elderly.
    Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:11

    Topics: Aged; Amikacin; Dizziness; Gentamicins; Glomerulonephritis; Hearing Disorders; Humans; Tinnitus; Ver

1987