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gentamicin and Disease Exacerbation

gentamicin has been researched along with Disease Exacerbation in 19 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
", amikacin and tobramycin) have been shown to be tolerable and effective in the treatment of acute pulmonary exacerbations (APEs) in both pediatric and adult patients with cystic fibrosis."4.89Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: V. Aminoglycosides. ( Ampofo, K; Sherwin, CM; Spigarelli, MG; Stockmann, C; Waters, CD; Young, DC; Zobell, JT, 2013)
"Glioma is a CNS tumor with few therapeutic options."1.56Gut microbiota alterations affect glioma growth and innate immune cells involved in tumor immunosurveillance in mice. ( Antonangeli, F; D'Alessandro, G; Lauro, C; Limatola, C; Marrocco, F; Porzia, A; Santoni, A, 2020)
"Highest contributors were infections (30%) and medications that may worsen MG (19%), with 24% unattributed."1.51Factors associated with acute exacerbations of myasthenia gravis. ( Deroche, CB; Govindarajan, R; Gummi, RR; Kukulka, NA, 2019)
"The Cystic Fibrosis Foundation recently deemed the use of extended-interval dosing (EID) of aminoglycosides acceptable for the treatment of cystic fibrosis (CF) pulmonary exacerbations."1.40A survey of extended-interval aminoglycoside dosing practices in United States adult cystic fibrosis programs. ( Prescott, WA, 2014)
"To study the effects of gentamicin in combination with ascorbic acid on septic arthritis, mice were infected with Staphylococcus aureus (S."1.38Gentamicin in combination with ascorbic acid regulates the severity of Staphylococcus aureus infection-induced septic arthritis in mice. ( Bandyopadhyay, D; Basu, A; Bishayi, B; Dutta, K; Dutta, S; Mal, P, 2012)
"Gentamicin treatment causes tubular necrosis at day 3, followed by tubular regenerative changes and interstitial fibrosis, which was most prominent at day 14."1.30Expression of the heat shock protein 47 in gentamicin-treated rat kidneys. ( Cheng, M; Nazneen, A; Razzaque, MS; Taguchi, T, 1998)
"Osteomyelitis is generally treated by the systemic administration of antibiotics and continuous irrigation after curettage of the lesion, and bone graft is performed secondarily to treat any bone defect."1.30Apatite cement containing antibiotics: efficacy in treating experimental osteomyelitis. ( Ishii, Y; Sasaki, S, 1999)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (15.79)18.2507
2000's5 (26.32)29.6817
2010's9 (47.37)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Gummi, RR1
Kukulka, NA1
Deroche, CB1
Govindarajan, R1
D'Alessandro, G1
Antonangeli, F1
Marrocco, F1
Porzia, A1
Lauro, C1
Santoni, A1
Limatola, C1
Dagneaux, L1
Limberg, AK1
Osmon, DR1
Leung, N1
Berry, DJ1
Abdel, MP1
Matsushita, K1
Takasu, S1
Kuroda, K1
Ishii, Y2
Kijima, A1
Ogawa, K1
Umemura, T1
Young, DC1
Zobell, JT1
Stockmann, C1
Waters, CD1
Ampofo, K1
Sherwin, CM1
Spigarelli, MG1
Prescott, WA1
Ibraheem, ZO2
Basir, R1
Aljobory, AKh1
Ibrahim, OE1
Alsumaidaee, A1
Yam, MF1
Vaynsthein, G1
Gurlanik, L1
Markel, A1
Rocha Araújo, FD1
Brandão, KN1
Araújo, FA1
Vasconcelos Severiano, GM1
Alves Meira, ZM1
Sattar, MA1
Abdullah, NA1
Rathore, HA1
Johns, EJ1
Chen, L1
Xiong, S1
Liu, Y1
Shang, X1
Mal, P1
Dutta, S1
Bandyopadhyay, D1
Dutta, K1
Basu, A1
Bishayi, B1
Gray, RF1
Jones, SE1
Court, I1
Almuzara, MN1
Mariñansky, AL1
Valenzuela, VC1
Vay, CA1
Ryzhkova, VV1
Pavlovich, NV1
Makarovskaia, LN1
Zurabian, VA1
Bespalova, IA1
Goncharov, EK1
Bugaeva, OK1
Malsova, NN1
Cheng, M1
Razzaque, MS1
Nazneen, A1
Taguchi, T1
Sasaki, S1
Ackermann, G1
Schoen, H1
Schaumann, R1
Dietrich, J1
Rodloff, AC1
Hirakata, Y1
Srikumar, R1
Poole, K1
Gotoh, N1
Suematsu, T1
Kohno, S1
Kamihira, S1
Hancock, RE1
Speert, DP1

Reviews

1 review available for gentamicin and Disease Exacerbation

ArticleYear
Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: V. Aminoglycosides.
    Pediatric pulmonology, 2013, Volume: 48, Issue:11

    Topics: Adult; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Child; Cystic Fibrosis; Disease Progression

2013

Other Studies

18 other studies available for gentamicin and Disease Exacerbation

ArticleYear
Factors associated with acute exacerbations of myasthenia gravis.
    Muscle & nerve, 2019, Volume: 60, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Disease P

2019
Gut microbiota alterations affect glioma growth and innate immune cells involved in tumor immunosurveillance in mice.
    European journal of immunology, 2020, Volume: 50, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Bacterial Typing Techniques; Brain Neoplasms; Cell Line, Tumor; Dise

2020
Acute Kidney Injury When Treating Periprosthetic Joint Infections After Total Knee Arthroplasties with Antibiotic-Loaded Spacers: Incidence, Risks, and Outcomes.
    The Journal of bone and joint surgery. American volume, 2021, 05-05, Volume: 103, Issue:9

    Topics: Acute Kidney Injury; Administration, Oral; Adult; Aged; Aged, 80 and over; Amphotericin B; Anti-Bact

2021
Mechanisms Underlying Exacerbation of Osmotic Nephrosis Caused by Pre-existing Kidney Injury.
    Toxicological sciences : an official journal of the Society of Toxicology, 2018, 10-01, Volume: 165, Issue:2

    Topics: Acute Kidney Injury; Animals; Dextrans; Disease Models, Animal; Disease Progression; Female; Gentami

2018
A survey of extended-interval aminoglycoside dosing practices in United States adult cystic fibrosis programs.
    Respiratory care, 2014, Volume: 59, Issue:9

    Topics: Adult; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Cystic Fibrosis; Disease Progression; Drug

2014
Impact of gentamicin coadministration along with high fructose feeding on progression of renal failure and metabolic syndrome in Sprague-Dawley rats.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Blood Glucose; Body Weight; Disease Progression; Drug Combinations; Fructose; Gentamicins;

2014
Gardner's syndrome in a 75-year-old woman.
    Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:16

    Topics: Adenomatous Polyposis Coli; Aged; Ampicillin; Anti-Bacterial Agents; Disease Progression; Female; Ga

2008
Cardiac tamponade as a rare form of presentation of rheumatic carditis.
    The American heart hospital journal, 2010,Summer, Volume: 8, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Captopril; Cardiac Tampona

2010
Effect of high saturated free fatty acids feeding on progression of renal failure in rat model of experimental nephrotoxicity.
    Bosnian journal of basic medical sciences, 2012, Volume: 12, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Disease Progression; Fatty Acids; Fatty Acid

2012
Effect of different gentamicin dose on the plasticity of the ribbon synapses in cochlear inner hair cells of C57BL/6J mice.
    Molecular neurobiology, 2012, Volume: 46, Issue:2

    Topics: Animals; Disease Progression; Dose-Response Relationship, Drug; Gentamicins; Hair Cells, Auditory, I

2012
Gentamicin in combination with ascorbic acid regulates the severity of Staphylococcus aureus infection-induced septic arthritis in mice.
    Scandinavian journal of immunology, 2012, Volume: 76, Issue:6

    Topics: Animals; Arthritis, Infectious; Ascorbic Acid; Cells, Cultured; Disease Progression; Drug Synergism;

2012
Cochlear implantation for progressive hearing loss.
    Archives of disease in childhood, 2003, Volume: 88, Issue:8

    Topics: Adolescent; Age Factors; Anti-Bacterial Agents; Audiometry, Pure-Tone; Child; Cochlear Implantation;

2003
[Endocarditis due to Rothia dentocariosa complicated by septic cerebral embolism].
    Enfermedades infecciosas y microbiologia clinica, 2004, Volume: 22, Issue:4

    Topics: Adult; Anisocoria; Disease Progression; Drug Therapy, Combination; Endocarditis, Bacterial; Female;

2004
[Increased effectiveness of etiotropic therapy of experimental plague in albino mice at the stage of generalized infection].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1996, Volume: 41, Issue:2

    Topics: Amikacin; Animals; Anti-Infective Agents; Ciprofloxacin; Disease Progression; Drug Evaluation, Precl

1996
Expression of the heat shock protein 47 in gentamicin-treated rat kidneys.
    International journal of experimental pathology, 1998, Volume: 79, Issue:3

    Topics: Actins; Animals; Anti-Bacterial Agents; Collagen; Disease Progression; Gentamicins; Heat-Shock Prote

1998
Apatite cement containing antibiotics: efficacy in treating experimental osteomyelitis.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 1999, Volume: 4, Issue:5

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Apatites; Bone Cements; Bone Marrow; Bone T

1999
Rapidly growing tumor-like brain lesion.
    Infection, 2001, Volume: 29, Issue:5

    Topics: Adrenal Cortex Hormones; Ampicillin; Anti-Bacterial Agents; Brain Abscess; Brain Neoplasms; Diagnosi

2001
Multidrug efflux systems play an important role in the invasiveness of Pseudomonas aeruginosa.
    The Journal of experimental medicine, 2002, Jul-01, Volume: 196, Issue:1

    Topics: Animals; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Translocation; Carrier Pro

2002