gentamicin has been researched along with Discitis in 21 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Discitis: Inflammation of an INTERVERTEBRAL DISC or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An injectable calcium sulfate/hydroxyapatite composite releasing a high level of gentamicin can support the surgical treatment of spondylodiscitis in combination with posterior debridement and transpedicular screw-rod instrumentation." | 7.83 | First report on treating spontaneous infectious spondylodiscitis of lumbar spine with posterior debridement, posterior instrumentation and an injectable calcium sulfate/hydroxyapatite composite eluting gentamicin: a case report. ( Bostelmann, R; Scholz, AO; Steiger, HJ, 2016) |
| " Here we investigated the handling, efficacy and compatibility of PerOssal when loaded with gentamicin or vancomycin in 19 patients with spondylodiscitis in vivo." | 5.14 | Effectiveness of combination use of antibiotic-loaded PerOssal with spinal surgery in patients with spondylodiscitis. ( Rauschmann, MA; von Stechow, D, 2009) |
| "An injectable calcium sulfate/hydroxyapatite composite releasing a high level of gentamicin can support the surgical treatment of spondylodiscitis in combination with posterior debridement and transpedicular screw-rod instrumentation." | 3.83 | First report on treating spontaneous infectious spondylodiscitis of lumbar spine with posterior debridement, posterior instrumentation and an injectable calcium sulfate/hydroxyapatite composite eluting gentamicin: a case report. ( Bostelmann, R; Scholz, AO; Steiger, HJ, 2016) |
| "To report the incidence of postoperative spondylodiscitis in cases in which no antibiotic prophylaxis was used, and to define the value of a collagenous sponge containing gentamicin in preventing disc space infections." | 3.70 | Spondylodiscitis after lumbar discectomy. Incidence and a proposal for prophylaxis. ( Hassler, WE; Meyer, B; Rohde, V; Schaller, C, 1998) |
| "We present two adult patients with GBS spondylodiscitis and review 30 cases of GBS spinal infection previously reported in the literature." | 2.42 | Group B streptococcal spondylodiscitis in adults: 2 case reports. ( Castro-Bohorquez, FJ; Narváez, J; Pérez-Vega, C; Vilaseca-Momplet, J, 2004) |
| "Spondylodiscitis is a challenging spinal disorder that requires surgical treatment only as a last resort." | 1.51 | Transforaminal Lumbar Interbody Fusion with Antibiotics Delivered by CaSO ( Liu, H; Wu, W; Yang, K; Zhang, S, 2019) |
| "Iatrogenic bacterial discitis is a rare but serious complication." | 1.36 | In vitro assessment of the antibiotic efficacy of contrast media and antibiotics and their combinations at various dilutions. ( Azimullah, S; Langer, RD; Lorke, DE; Nurulain, SM; Petroianu, G; Usmani, A; van Gorkom, KN, 2010) |
| "We report here the first case of C." | 1.36 | Spondylodiscitis and an aortic aneurysm due to Campylobacter coli. ( Bournet, BS; Cattoen, C; Dehecq, C; Garnier, LD; Lemaire, X; Senneville, E; Yazdanpanah, Y, 2010) |
| "A 68-year-old man with septic discitis of low lumbar spine is presented." | 1.33 | Septic discitis as initial manifestation of streptococcus bovis endocarditis. ( Gonzalez-Gay, MA; Gonzalez-Juanatey, C; Testa-Fernandez, A, 2006) |
| "cloxacillin, she was released from hospital with instructions to continue cloxacillin orally for another 4 weeks." | 1.30 | [Discitis in brucellosis is not responsive to anti-brucella treatment]. ( Heldenberg, D; Sevi, R, 1998) |
| "Spondylodiscitis by enterococcus is a very infrequent disease with only 2 cases caused exclusively by this microorganism having been reported in the literature." | 1.29 | [Spondylodiscitis caused by Enterococcus: an unusual entity]. ( Capdevila, JA; Fernández-Solà, A; García Quintana, AM; García, F, 1995) |
| "Spondylodiscitis after lumbar disc surgery is a well-known complication with a frequency of 0." | 1.28 | Prophylaxis of postoperative lumbar spondylodiscitis. ( Frank, AM; Trappe, AE; Zink, PM, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Russo, A | 1 |
| Venditti, M | 1 |
| Yang, K | 1 |
| Zhang, S | 1 |
| Liu, H | 1 |
| Wu, W | 1 |
| Ferroni, A | 1 |
| Al Khoury, H | 1 |
| Dana, C | 1 |
| Quesne, G | 1 |
| Berche, P | 1 |
| Glorion, C | 1 |
| Péjin, Z | 1 |
| Saidane, O | 1 |
| Mahmoud, I | 1 |
| Saadi, F | 1 |
| Souayah, A | 1 |
| Zouari, R | 1 |
| Bostelmann, R | 1 |
| Steiger, HJ | 1 |
| Scholz, AO | 1 |
| von Stechow, D | 1 |
| Rauschmann, MA | 1 |
| Langer, RD | 1 |
| Usmani, A | 1 |
| van Gorkom, KN | 1 |
| Lorke, DE | 1 |
| Petroianu, G | 1 |
| Azimullah, S | 1 |
| Nurulain, SM | 1 |
| Lemaire, X | 1 |
| Dehecq, C | 1 |
| Cattoen, C | 1 |
| Garnier, LD | 1 |
| Bournet, BS | 1 |
| Yazdanpanah, Y | 1 |
| Senneville, E | 1 |
| Renwick, AI | 1 |
| Dennis, R | 1 |
| Gemmill, TJ | 1 |
| Klessig, HT | 1 |
| Showsh, SA | 1 |
| Sekorski, A | 1 |
| Narváez, J | 1 |
| Pérez-Vega, C | 1 |
| Castro-Bohorquez, FJ | 1 |
| Vilaseca-Momplet, J | 1 |
| Gonzalez-Juanatey, C | 1 |
| Testa-Fernandez, A | 1 |
| Gonzalez-Gay, MA | 1 |
| Tekin, A | 1 |
| Tekin, G | 1 |
| Turunç, T | 1 |
| Demiroğlu, Z | 1 |
| Kizilkiliç, O | 1 |
| Lin, SS | 1 |
| Vaccaro, AR | 1 |
| Reisch, S | 1 |
| Devine, M | 1 |
| Cotler, JM | 1 |
| Reich, SM | 1 |
| García, F | 1 |
| Fernández-Solà, A | 1 |
| García Quintana, AM | 1 |
| Capdevila, JA | 1 |
| Rohde, V | 1 |
| Meyer, B | 1 |
| Schaller, C | 1 |
| Hassler, WE | 1 |
| Heldenberg, D | 1 |
| Sevi, R | 1 |
| Wong, EB | 1 |
| Vaverka, M | 1 |
| Petrzelová, J | 1 |
| Zink, PM | 1 |
| Frank, AM | 1 |
| Trappe, AE | 1 |
| Alexander, JW | 1 |
| Solangi, MA | 1 |
| Riegel, LS | 1 |
2 reviews available for gentamicin and Discitis
| Article | Year |
|---|---|
Group B streptococcal spondylodiscitis in adults: 2 case reports.
Topics: Aged; Ampicillin; Diagnosis, Differential; Discitis; Drug Therapy, Combination; Female; Gentamicins; | 2004 |
Low-velocity gunshot wounds to the spine with an associated transperitoneal injury.
Topics: Adolescent; Adult; Antifungal Agents; Cefoxitin; Child; Colon; Discitis; Drug Therapy, Combination; | 1995 |
1 trial available for gentamicin and Discitis
| Article | Year |
|---|---|
Effectiveness of combination use of antibiotic-loaded PerOssal with spinal surgery in patients with spondylodiscitis.
Topics: Adult; Aged; Anti-Bacterial Agents; Calcium Sulfate; Discitis; Drug Therapy, Combination; Durapatite | 2009 |
18 other studies available for gentamicin and Discitis
| Article | Year |
|---|---|
Vertebral osteomyelitis caused by vancomycin-resistant Enterococcus spp.: a case series.
Topics: Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Daptomycin; Discitis; Drug Resistance, M | 2021 |
Transforaminal Lumbar Interbody Fusion with Antibiotics Delivered by CaSO
Topics: Adult; Aged; Anti-Bacterial Agents; Calcium Sulfate; Discitis; Drug Carriers; Female; Gentamicins; H | 2019 |
Prospective survey of acute osteoarticular infections in a French paediatric orthopedic surgery unit.
Topics: Adolescent; Anti-Bacterial Agents; Arthritis, Infectious; Cefamandole; Child; Child, Preschool; Disc | 2013 |
[Spondylodiscitis and Lactococcus cremoris endocarditis].
Topics: Aged; Animals; Anti-Bacterial Agents; Bacteremia; Braces; Cattle; Combined Modality Therapy; Disciti | 2013 |
First report on treating spontaneous infectious spondylodiscitis of lumbar spine with posterior debridement, posterior instrumentation and an injectable calcium sulfate/hydroxyapatite composite eluting gentamicin: a case report.
Topics: Anti-Bacterial Agents; Biocompatible Materials; Bone Screws; Calcium Sulfate; Debridement; Discitis; | 2016 |
In vitro assessment of the antibiotic efficacy of contrast media and antibiotics and their combinations at various dilutions.
Topics: Ampicillin; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Ceftriaxone; Contra | 2010 |
Spondylodiscitis and an aortic aneurysm due to Campylobacter coli.
Topics: Aged; Anti-Bacterial Agents; Aortic Aneurysm, Abdominal; Bacteremia; Campylobacter coli; Campylobact | 2010 |
Treatment of lumbosacral discospondylitis by surgical stabilisation and application of a gentamicin-impregnated collagen sponge.
Topics: Animals; Anti-Bacterial Agents; Discitis; Dog Diseases; Dogs; Female; Gentamicins; Lameness, Animal; | 2010 |
The use of intradiscal antibiotics for discography: an in vitro study of gentamicin, cefazolin, and clindamycin.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteria; Cefazolin; Cell Division; Clindamycin; Cont | 2003 |
Septic discitis as initial manifestation of streptococcus bovis endocarditis.
Topics: Aged; Anti-Bacterial Agents; Bioprosthesis; Ceftriaxone; Discitis; Drug Therapy, Combination; Endoca | 2006 |
Infective endocarditis and spondylodiscitis in a patient due to Aerococcus urinae: first report.
Topics: Aged; Anti-Bacterial Agents; Discitis; Drug Therapy, Combination; Endocarditis; Follow-Up Studies; G | 2007 |
[Spondylodiscitis caused by Enterococcus: an unusual entity].
Topics: Aged; Amoxicillin; Combined Modality Therapy; Diabetes Mellitus, Type 2; Discitis; Drug Therapy, Com | 1995 |
Spondylodiscitis after lumbar discectomy. Incidence and a proposal for prophylaxis.
Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Discitis; Diskectomy; Female; Gentamicins; Hu | 1998 |
[Discitis in brucellosis is not responsive to anti-brucella treatment].
Topics: Adolescent; Brucellosis; Cloxacillin; Discitis; Doxycycline; Drug Therapy, Combination; Female; Gent | 1998 |
Back pain in an elderly man--more than just a fall.
Topics: Accidental Falls; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Back Pain; Bacteremia | 2000 |
[Penetration of antibiotics into the intervertebral disk].
Topics: Discitis; Gentamicins; Humans; Intervertebral Disc; Postoperative Complications; Premedication; Roli | 1991 |
Prophylaxis of postoperative lumbar spondylodiscitis.
Topics: Adult; Aged; Discitis; Drug Implants; Female; Gentamicins; Humans; Intervertebral Disc; Lumbar Verte | 1989 |
Vertebral osteomyelitis and suspected diskospondylitis in an Atlantic bottlenose dolphin (Tursiops truncatus).
Topics: Ampicillin; Animals; Discitis; Dolphins; Drug Therapy, Combination; Gentamicins; Lumbosacral Region; | 1989 |