Page last updated: 2024-10-27

gentamicin and Deafness

gentamicin has been researched along with Deafness in 74 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Deafness: A general term for the complete loss of the ability to hear from both ears.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to examine the effect of intratympanically applied gentamicin (GM) (30 mg/mL) on hearing and tinnitus in patients with intractable Meniere's disease."9.09Effect of intratympanic gentamicin on hearing and tinnitus in Meniere's disease. ( Aalto, H; Eklund, S; Ishizaki, H; Pyykkö, I; Vasama, JP, 1999)
"To explore an effective method for treating Gentamicin-induced deafness and the mechanism."7.74[Effect of acupuncture on target action of ligustrazine in treatment of toxic deafness induced by gentamicin in guinea pigs]. ( Fan, BH; Liu, JH; Wang, F; Wang, P; Wang, YH; Xu, F; Xu, QZ; Zhang, GJ; Zheng, HP, 2008)
"The purpose of this study is to discuss the effects of the Chinese medicine six-flavor Rehmannia Decoction with additives on preventing deafness induced by gentamicin (GM) in guinea pig by means of testing the thresholds of Preyer's reflex (PR) cochlear microphonic potential (CM), action potential of the auditory nerve (N1) and scanning electron microscope of inner ear (SEM)."7.68[The use of 6-flavor Rehmannia decoction with additives in the prevention of ototoxic deafness induced by gentamicin in guinea pigs]. ( Han, T; Hu, S; Sun, Y; Xu, F; Zeng, Z; Zhang, M; Zhuang, J, 1992)
"The objective of this study was to examine the effect of intratympanically applied gentamicin (GM) (30 mg/mL) on hearing and tinnitus in patients with intractable Meniere's disease."5.09Effect of intratympanic gentamicin on hearing and tinnitus in Meniere's disease. ( Aalto, H; Eklund, S; Ishizaki, H; Pyykkö, I; Vasama, JP, 1999)
"Children with hearing loss had lower birth weight for gestational age, more severe neonatal illness, with increased exposure to inotrope, steroid, gentamicin, vancomycin and furosemide, and more frequent physiological risk, elevated bilirubin and creatinine levels and acidosis, but no index child was found to have the m."4.31Cumulative risk factors contributing to hearing loss in preterm infants. ( Bitner-Glindzicz, M; Chant, K; Marlow, N, 2023)
"Ototoxic drugs given to sick infants with "fever", without weight recording or gentamicin level monitoring, was the probable cause of a third of all severe/profound deafened Zanzibarian children."3.76Sensorineural deafness in Tanzanian children--is ototoxicity a significant cause? A pilot study. ( Freeland, A; Jones, J; Mohammed, NK, 2010)
"To explore an effective method for treating Gentamicin-induced deafness and the mechanism."3.74[Effect of acupuncture on target action of ligustrazine in treatment of toxic deafness induced by gentamicin in guinea pigs]. ( Fan, BH; Liu, JH; Wang, F; Wang, P; Wang, YH; Xu, F; Xu, QZ; Zhang, GJ; Zheng, HP, 2008)
"Guinea pig deafness model was prepared by injection of gentamicin (GM)."3.74[Observation on acupuncture at "Neitinggong" for antagonisting ototoxicity caused by gentamicin]. ( Li, HY; Liu, H; Ma, WJ; Xu, M; Zhang, XT; Zhou, XH, 2007)
"It was concluded that increasing the gentamicin concentration to 40 mg/ml probably produces similar rates of vertigo control as those of the lower dose, at least initially, but requires fewer injections."3.71Efficacy of increased gentamicin concentration for intratympanic injection therapy in Ménière's disease. ( Abou-Halawa, AS; Poe, DS, 2002)
"The purpose of this study is to discuss the effects of the Chinese medicine six-flavor Rehmannia Decoction with additives on preventing deafness induced by gentamicin (GM) in guinea pig by means of testing the thresholds of Preyer's reflex (PR) cochlear microphonic potential (CM), action potential of the auditory nerve (N1) and scanning electron microscope of inner ear (SEM)."3.68[The use of 6-flavor Rehmannia decoction with additives in the prevention of ototoxic deafness induced by gentamicin in guinea pigs]. ( Han, T; Hu, S; Sun, Y; Xu, F; Zeng, Z; Zhang, M; Zhuang, J, 1992)
"A case of profound bilateral sensorineural deafness occurring during gentamicin therapy is presented."3.65Profound bilateral sensorineural hearing loss during gentamicin therapy. ( Moffat, DA; Ramsden, RT, 1977)
"For the medically refractory Meniere's disease patient, treatment options include intratympanic steroid injection, endolymphatic sac decompression, medical or surgical labyrinthectomy, and vestibular nerve section."3.01Recent surgical advances and continued controversies in medically refractory Meniere's disease. ( Hong, RS; Lucas, JC, 2023)
"5-Å resolution, our results provide a conceptual framework for further development of less toxic aminoglycosides by hypothesis-driven chemical synthesis."1.38Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin. ( Akbergenov, R; Böttger, EC; Dubbaka, SR; Duscha, S; Lang, K; Matt, T; Meyer, M; Ng, CL; Perez-Fernandez, D; Ramakrishnan, V; Schacht, J; Sha, SH; Shcherbakov, D; Vasella, A; Xie, J, 2012)
"When melatonin was present, the recovery was at day 5 post-treatment, independently of the means of administration of the pineal product."1.31Ototoxicity caused by aminoglycosides is ameliorated by melatonin without interfering with the antibiotic capacity of the drugs. ( Delgado, F; Guerrero, JM; Lopez-Gonzalez, MA; Osuna, C; Torronteras, R, 2000)
" These patients would consequently be expected to be more susceptible to cochleotoxicity, a recognized side effect with single courses of aminoglycoside therapy."1.31Occurrence and risk of cochleotoxicity in cystic fibrosis patients receiving repeated high-dose aminoglycoside therapy. ( Burr, S; Degg, C; Morgan, DW; Mulheran, M; Stableforth, DE, 2001)
"Ciprofloxacin is an alternative, and there is limited experience in its topical use."1.30Investigation of topical ciprofloxacin ototoxicity in guinea pigs. ( Ceryan, K; Güneri, EA; Ikiz, AO; Serbetçioğlu, B; Sütay, S, 1998)
"Gentamicin can cause ototoxic damage to cochlear hair cells responsible for high frequency hearing."1.30Tonotopic changes in 2-deoxyglucose activity in chick cochlear nucleus during hair cell loss and regeneration. ( Durham, D; Girod, DA; Park, DL, 1999)
"Deafness was caused by a prolonged course of intravenous gentamycin therapy 5 years prior to implantation."1.29Otopathology in a case of multichannel cochlear implantation. ( Burgess, BJ; Ketten, DR; Nadol, JB, 1994)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-199031 (41.89)18.7374
1990's15 (20.27)18.2507
2000's21 (28.38)29.6817
2010's5 (6.76)24.3611
2020's2 (2.70)2.80

Authors

AuthorsStudies
Chant, K2
Bitner-Glindzicz, M2
Marlow, N2
Lucas, JC1
Hong, RS1
Reynard, P1
Karkas, A1
Gavid, M1
Lelonge, Y1
Bertholon, P1
Rahman, S1
Song, BN1
Li, YX1
Han, DM1
Zheng, HP1
Wang, F1
Xu, QZ1
Xu, F2
Zhang, GJ1
Wang, P1
Wang, YH1
Liu, JH1
Fan, BH1
Han, Y2
Qiu, J3
Qiao, L2
Zhong, C2
Hong, L1
Xue, T1
He, Y1
Chen, J1
Chunyu, X1
Freeland, A1
Jones, J1
Mohammed, NK1
Kawashima, Y1
Géléoc, GS1
Kurima, K1
Labay, V1
Lelli, A1
Asai, Y1
Makishima, T1
Wu, DK1
Della Santina, CC1
Holt, JR1
Griffith, AJ1
Matt, T1
Ng, CL1
Lang, K1
Sha, SH1
Akbergenov, R1
Shcherbakov, D1
Meyer, M1
Duscha, S1
Xie, J1
Dubbaka, SR1
Perez-Fernandez, D1
Vasella, A1
Ramakrishnan, V1
Schacht, J2
Böttger, EC1
Abou-Halawa, AS1
Poe, DS1
Koitschev, A1
Lange, G2
Mann, W1
Maurer, J1
Lautermann, J1
Dehne, N1
Jahnke, K1
Deng, Z1
Wang, J1
Liu, S1
Wang, C1
Yang, A1
Radeloff, A1
Smolders, JW1
Jafari, Z1
Malayeri, S1
Ashayeri, H1
Ma, WJ1
Xu, M1
Zhang, XT1
Liu, H1
Li, HY1
Zhou, XH1
Hurley, PA1
Crook, JM1
Shepherd, RK1
Bochenek, W1
Chorzempa, A1
Morrison, AW1
Tange, RA1
Huizing, EH3
Henley, CM1
Rybak, LP1
O'Brien, RK1
Sparling, TG1
Kawashiro, N1
Tsuchihashi, N1
Koga, K1
Ito, Y1
Kawano, H1
Nadol, JB1
Ketten, DR1
Burgess, BJ1
Kohn, S1
Fradis, M1
Podoshin, L1
David, YB1
Zidan, J1
Robinson, E1
Nir, I1
Conlon, BJ1
Smith, DW1
Wu, J1
Marais, J1
Rutka, JA1
Ikiz, AO1
Serbetçioğlu, B1
Güneri, EA1
Sütay, S1
Ceryan, K1
Kang, S1
He, C1
Shi, X1
Eklund, S1
Pyykkö, I1
Aalto, H1
Ishizaki, H1
Vasama, JP1
Park, DL1
Girod, DA1
Durham, D1
Lopez-Gonzalez, MA1
Guerrero, JM1
Torronteras, R1
Osuna, C1
Delgado, F1
Keller, R1
Gao, WQ1
Stockwell, M1
Walsted, A1
Dodson, HC1
Mohuiddin, A1
Yuan, H1
Jiang, S1
Yang, W1
Mulheran, M1
Degg, C1
Burr, S1
Morgan, DW1
Stableforth, DE1
Akagi, H1
Yuen, K1
Maeda, Y1
Fukushima, K1
Kariya, S1
Orita, Y1
Kataoka, Y1
Ogawa, T1
Nishizaki, K1
Gale, JE1
Meyers, JR1
Periasamy, A1
Corwin, JT1
Clark, CH1
Echeverria, P1
Fina, D1
Norton, S1
Smith, AL1
Beck, C1
Schmidt, CL1
Weichselbaumer, W1
Gorz, E1
Moffat, DA1
Ramsden, RT1
Leisinger, HJ1
Zhuang, J2
Zhang, M1
Zeng, Z1
Han, T1
Hu, S1
Sun, Y1
Xing, J1
Sheng, J1
Khosla, SN1
Nand, N1
Khosla, P1
Kumar, P1
Martin, H1
Gadot, P1
Gignoux, B1
Selavri, TV1
Debain, JJ1
Freyss, G1
Poulain, H1
VanOmmen, RA1
Sugarbaker, PH1
Sabath, LD1
Morgan, AP1
Brown, CB1
Ogg, CS1
Cameron, JS1
Bewick, M1
Conde Jahn, F1
Ellis, W1
Lehnhardt, E1
Schwarz, GA1
Blumenkrantz, MJ1
Sundmäker, WL1
Johnsson, LG1
Hawkins, JE1
Arcieri, GM1
Falco, FG1
Smith, HM1
Hobson, LB1
Pirsig, W1
Rollin, H1
Stephens, SD1

Reviews

7 reviews available for gentamicin and Deafness

ArticleYear
Recent surgical advances and continued controversies in medically refractory Meniere's disease.
    Current opinion in otolaryngology & head and neck surgery, 2023, Oct-01, Volume: 31, Issue:5

    Topics: Deafness; Ear, Inner; Gentamicins; Hearing Loss; Humans; Meniere Disease; Vertigo

2023
[Aminoglycoside- and cisplatin-ototoxicity: from basic science to clinics].
    Laryngo- rhino- otologie, 2004, Volume: 83, Issue:5

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Cisplatin; Deafne

2004
Ototoxicity in developing mammals.
    Brain research. Brain research reviews, 1995, Volume: 20, Issue:1

    Topics: Age Distribution; Age Factors; Animals; Animals, Newborn; Cochlea; Deafness; Diuretics; Ear, Inner;

1995
Toxicity of aminoglycoside antibiotics.
    Modern veterinary practice, 1977, Volume: 58, Issue:7

    Topics: Aminoglycosides; Animals; Ataxia; Cat Diseases; Cats; Deafness; Dog Diseases; Dogs; Gentamicins; Hea

1977
[Side effects of antibiotics-aminoglycosides].
    Sovetskaia meditsina, 1972, Volume: 35, Issue:7

    Topics: Age Factors; Aged; Animals; Anti-Bacterial Agents; Deafness; Drug Resistance, Microbial; Ear Disease

1972
Committee on Environmental Hazards. Noise pollution: neonatal aspects.
    Pediatrics, 1974, Volume: 54, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Cats; Deafness; Environmental Exposure; Gentamicins; Guinea Pi

1974
[Ototoxicity of antibiotics].
    HNO, 1970, Volume: 18, Issue:4

    Topics: Anti-Bacterial Agents; Deafness; Gentamicins; Humans; Kanamycin; Neomycin; Organ of Corti; Petrous B

1970

Trials

2 trials available for gentamicin and Deafness

ArticleYear
Effect of intratympanic gentamicin on hearing and tinnitus in Meniere's disease.
    The American journal of otology, 1999, Volume: 20, Issue:3

    Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Deafness; Decomp

1999
High dose frusemide in acute reversible intrinsic renal failure. A preliminary communication.
    Scottish medical journal, 1974, Volume: 19 Suppl 1

    Topics: Acute Kidney Injury; Adult; Clinical Trials as Topic; Deafness; Furosemide; Gentamicins; Humans; Kan

1974

Other Studies

65 other studies available for gentamicin and Deafness

ArticleYear
Cumulative risk factors contributing to hearing loss in preterm infants.
    Archives of disease in childhood. Fetal and neonatal edition, 2023, Volume: 108, Issue:5

    Topics: Case-Control Studies; Child; Deafness; Furosemide; Gentamicins; Hearing Loss; Humans; Infant; Infant

2023
Delayed endolymphatic hydrops. Special emphasis on nystagmus associated with episodes and contribution of chemical labyrinthectomy.
    European annals of otorhinolaryngology, head and neck diseases, 2018, Volume: 135, Issue:5

    Topics: Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Deafness; Endolymphatic Hydrops; Female; Gentamic

2018
Gentamicin, genetic variation and deafness in preterm children.
    BMC pediatrics, 2014, Mar-05, Volume: 14

    Topics: Anti-Bacterial Agents; Case-Control Studies; Deafness; Female; Genetic Variation; Gentamicins; Human

2014
Delayed electrical stimulation and BDNF application following induced deafness in rats.
    Acta oto-laryngologica, 2009, Volume: 129, Issue:2

    Topics: Animals; Auditory Threshold; Brain-Derived Neurotrophic Factor; Cell Survival; Cochlea; Combined Mod

2009
[Effect of acupuncture on target action of ligustrazine in treatment of toxic deafness induced by gentamicin in guinea pigs].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2008, Volume: 28, Issue:7

    Topics: Acupuncture Therapy; Animals; Anti-Bacterial Agents; Deafness; Evoked Potentials, Auditory, Brain St

2008
Gentamicin-induced deafness may be reversed by restarting cell cycle.
    Medical hypotheses, 2009, Volume: 72, Issue:3

    Topics: Cell Cycle; Cell Cycle Proteins; Deafness; Gentamicins; Humans

2009
The expression of NOB1 in spiral ganglion cells of guinea pig.
    International journal of pediatric otorhinolaryngology, 2009, Volume: 73, Issue:2

    Topics: Animals; Deafness; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Gentamicins; Gui

2009
Sensorineural deafness in Tanzanian children--is ototoxicity a significant cause? A pilot study.
    International journal of pediatric otorhinolaryngology, 2010, Volume: 74, Issue:5

    Topics: Anti-Bacterial Agents; Antimalarials; Case-Control Studies; Child; Child, Preschool; Craniocerebral

2010
Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes.
    The Journal of clinical investigation, 2011, Volume: 121, Issue:12

    Topics: Animals; Cells, Cultured; Deafness; Female; Fluorescent Dyes; Genetic Complementation Test; Gentamic

2011
Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Jul-03, Volume: 109, Issue:27

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Binding Sites; Deaf

2012
Efficacy of increased gentamicin concentration for intratympanic injection therapy in Ménière's disease.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2002, Volume: 23, Issue:4

    Topics: Caloric Tests; Deafness; Dose-Response Relationship, Drug; Female; Gentamicins; Hearing; Humans; Inj

2002
[Transtympanic administration of gentamicin in Menière diseases--less is more!?].
    HNO, 2003, Volume: 51, Issue:11

    Topics: Anti-Bacterial Agents; Deafness; Dose-Response Relationship, Drug; Drug Administration Schedule; Ear

2003
[Intratympanic interval therapy of Menière disease with gentamicin with preserving cochlear function].
    HNO, 2003, Volume: 51, Issue:11

    Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Audiometry, Speech; Caloric Tests; Cochlea; Deafness;

2003
[Protection of NT3 gene transfection on the guinea pig cochlea treated with gentamicin].
    Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 2004, Volume: 18, Issue:4

    Topics: Animals; Cochlea; Deafness; Genetic Therapy; Gentamicins; Guinea Pigs; Neurotrophin 3; Transfection

2004
Brain-derived neurotrophic factor treatment does not improve functional recovery after hair cell regeneration in the pigeon.
    Acta oto-laryngologica, 2006, Volume: 126, Issue:5

    Topics: Administration, Topical; Animals; Auditory Threshold; Brain-Derived Neurotrophic Factor; Cochlea; Co

2006
The ages of suspicion, diagnosis, amplification, and intervention in deaf children.
    International journal of pediatric otorhinolaryngology, 2007, Volume: 71, Issue:1

    Topics: Age Distribution; Anti-Bacterial Agents; Birth Weight; Child, Preschool; Consanguinity; Cross-Sectio

2007
[Observation on acupuncture at "Neitinggong" for antagonisting ototoxicity caused by gentamicin].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2007, Volume: 27, Issue:3

    Topics: Acupuncture Points; Acupuncture Therapy; Animals; Anti-Bacterial Agents; Cochlea; Deafness; Evoked P

2007
Schwann cells revert to non-myelinating phenotypes in the deafened rat cochlea.
    The European journal of neuroscience, 2007, Volume: 26, Issue:7

    Topics: Animals; Animals, Newborn; Cochlea; Deafness; Disease Models, Animal; Evoked Potentials, Auditory, B

2007
Our experiences with the management of young postlingually deafened persons. Preliminary report.
    Scandinavian audiology. Supplementum, 1983, Volume: 17

    Topics: Adult; Deafness; Ear Neoplasms; Electric Stimulation; Evoked Potentials, Auditory; Female; Gentamici

1983
Sac surgery on the only or better hearing ear.
    Otolaryngologic clinics of North America, 1983, Volume: 16, Issue:1

    Topics: Adult; Cochlea; Deafness; Ear, Inner; Endolymphatic Sac; Female; Gentamicins; Humans; Iatrogenic Dis

1983
Hearing loss and inner ear changes in a patient suffering from severe gentamicin ototoxicity.
    Archives of oto-rhino-laryngology, 1980, Volume: 228, Issue:2

    Topics: Adult; Cochlea; Deafness; Female; Gentamicins; Hair Cells, Auditory; Hearing Loss, Sensorineural; Hu

1980
Gentamicin and fludarabine ototoxicity.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:2

    Topics: Aged; Antineoplastic Agents; Deafness; Dose-Response Relationship, Drug; Gentamicins; Humans; Leukem

1995
Idiopathic deafness or hearing loss of unknown etiology following discharge from the NICU.
    Acta oto-laryngologica. Supplementum, 1994, Volume: 514

    Topics: Child, Preschool; Deafness; Dyspnea; Evoked Potentials, Auditory, Brain Stem; Extracorporeal Membran

1994
Otopathology in a case of multichannel cochlear implantation.
    The Laryngoscope, 1994, Volume: 104, Issue:3 Pt 1

    Topics: Cell Count; Cochlea; Cochlear Implants; Deafness; Fatal Outcome; Female; Gentamicins; Humans; Middle

1994
Ototoxicity resulting from combined administration of cisplatin and gentamicin.
    The Laryngoscope, 1997, Volume: 107, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Cochlea; Deafness; Drug Combinatio

1997
Supplemental iron exacerbates aminoglycoside ototoxicity in vivo.
    Hearing research, 1998, Volume: 115, Issue:1-2

    Topics: Animals; Anti-Bacterial Agents; Auditory Threshold; Cochlea; Deafness; Dose-Response Relationship, D

1998
[Cross susceptibility of ototoxicity about aminoglycoside antibiotics].
    Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 1997, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Deafness; Disease Susceptibility; Family Health; Female; G

1997
Ototoxicity and topical eardrops.
    Clinical otolaryngology and allied sciences, 1998, Volume: 23, Issue:4

    Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Deafness; Female; Gentamicins; Humans; Male;

1998
Investigation of topical ciprofloxacin ototoxicity in guinea pigs.
    Acta oto-laryngologica, 1998, Volume: 118, Issue:6

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Auditory Threshold;

1998
[Protective effect of ciliary neurotrophic factor against the ototoxicity of gentamicin in guinea pigs].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 1997, Volume: 13, Issue:2

    Topics: Animals; Ciliary Neurotrophic Factor; Cochlear Microphonic Potentials; Deafness; Evoked Potentials,

1997
Tonotopic changes in 2-deoxyglucose activity in chick cochlear nucleus during hair cell loss and regeneration.
    Hearing research, 1999, Volume: 138, Issue:1-2

    Topics: Acoustic Stimulation; Animals; Animals, Newborn; Cell Death; Chickens; Cochlea; Cochlear Nucleus; De

1999
Ototoxicity caused by aminoglycosides is ameliorated by melatonin without interfering with the antibiotic capacity of the drugs.
    Journal of pineal research, 2000, Volume: 28, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Deafness; Escherichia coli; Female; Gentamicins; Hair Cells, Auditor

2000
[Bilateral malfunction of peripheral vestibular organs. Observations of 20 cases of Dandy syndrome].
    Laryngo- rhino- otologie, 2000, Volume: 79, Issue:2

    Topics: Anti-Bacterial Agents; Deafness; Dose-Response Relationship, Drug; Female; Functional Laterality; Ge

2000
Role of neurotrophins and lectins in prevention of ototoxicity.
    Annals of the New York Academy of Sciences, 1999, Nov-28, Volume: 884

    Topics: Animals; Anti-Bacterial Agents; Cell Survival; Cells, Cultured; Concanavalin A; Deafness; Gentamicin

1999
Gentamicin ear drops and ototoxicity: update.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2001, Jan-09, Volume: 164, Issue:1

    Topics: Administration, Topical; Anti-Bacterial Agents; Deafness; Gentamicins; Humans; Vestibular Diseases

2001
Unpredictable hearing loss after intratympanic gentamicin treatment for vertigo. A new theory.
    Acta oto-laryngologica, 2001, Volume: 121, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Deafness; Female; Gentamicins; Humans; Male; Meniere Disease; Ve

2001
Response of spiral ganglion neurones to cochlear hair cell destruction in the guinea pig.
    Journal of neurocytology, 2000, Volume: 29, Issue:7

    Topics: Animals; Apoptosis; Cell Size; Cell Survival; Deafness; GAP-43 Protein; Gentamicins; Guinea Pigs; Ha

2000
[Screening for the 1555G mutation in mitochondrial DNA in pedigrees with aminoglycoside antibiotic induced deafness].
    Zhonghua er bi yan hou ke za zhi, 1998, Volume: 33, Issue:2

    Topics: Anti-Bacterial Agents; Child; Deafness; DNA, Mitochondrial; Female; Genetic Predisposition to Diseas

1998
Occurrence and risk of cochleotoxicity in cystic fibrosis patients receiving repeated high-dose aminoglycoside therapy.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:9

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Audiometry, Pure-Tone; Child; Cystic Fibrosis; Deafness; D

2001
Ménière's disease in childhood.
    International journal of pediatric otorhinolaryngology, 2001, Dec-01, Volume: 61, Issue:3

    Topics: Adolescent; Anti-Bacterial Agents; Child; Deafness; Female; Gentamicins; Hearing Tests; Humans; Meni

2001
Survival of bundleless hair cells and subsequent bundle replacement in the bullfrog's saccule.
    Journal of neurobiology, 2002, Feb-05, Volume: 50, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Cell Survival; Cells, Cultured; Deafness; Gentamicins; Hair Cells, V

2002
Ototoxicity of gentamicin: clinical experience in a children's hospital.
    Chemotherapy, 1978, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Audiometry; Child; Deafness; Ear; Gentamicins; Humans

1978
10 years of experience with intratympanally applied streptomycin (gentamycin) in the therapy of Morbus Menière.
    Archives of oto-rhino-laryngology, 1978, Sep-28, Volume: 221, Issue:2

    Topics: Cochlea; Deafness; Epithelium; Gentamicins; Humans; Meniere Disease; Streptomycin; Time Factors

1978
[Tuberculosis of the middle and external ear; a report of two cases (author's transl)].
    Praxis der Pneumologie, 1977, Volume: 31, Issue:1

    Topics: Adult; Deafness; Ear Diseases; Ear, External; Ear, Middle; Female; Gentamicins; Humans; Isoniazid; M

1977
Profound bilateral sensorineural hearing loss during gentamicin therapy.
    The Journal of laryngology and otology, 1977, Volume: 91, Issue:6

    Topics: Adult; Audiometry; Deafness; Gentamicins; Humans; Male

1977
Proceedings: Hearing loss due to gentamicin therapy.
    ORL; journal for oto-rhino-laryngology and its related specialties, 1975, Volume: 37, Issue:6

    Topics: Audiometry; Deafness; Gentamicins; Humans

1975
[The dangers of antibiotic therapy in gram-negative pathogens (author's transl)].
    Der Urologe. Ausg. A, 1976, Volume: 15, Issue:1

    Topics: Acute Kidney Injury; Adult; Anuria; Bacterial Infections; Deafness; Drug Therapy, Combination; Femal

1976
[The use of 6-flavor Rehmannia decoction with additives in the prevention of ototoxic deafness induced by gentamicin in guinea pigs].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1992, Volume: 17, Issue:8

    Topics: Action Potentials; Animals; Cochlear Microphonic Potentials; Deafness; Drugs, Chinese Herbal; Gentam

1992
[Auditory brainstem response in ototoxic deafness].
    Zhonghua er bi yan hou ke za zhi, 1989, Volume: 24, Issue:4

    Topics: Adolescent; Child; Child, Preschool; Deafness; Evoked Potentials, Auditory, Brain Stem; Female; Gent

1989
[Factors causing deafness in deaf-mute students].
    Zhonghua er bi yan hou ke za zhi, 1989, Volume: 24, Issue:4

    Topics: Child, Preschool; Deafness; Female; Gentamicins; Humans; Infant; Kanamycin; Male; Streptomycin

1989
[A pedigree analysis of aminoglycoside antibiotic ototoxicity in 43 families].
    Zhonghua er bi yan hou ke za zhi, 1988, Volume: 23, Issue:3

    Topics: Anti-Bacterial Agents; Child; Child, Preschool; Deafness; Gentamicins; Humans; Infant; Kanamycin; Pe

1988
Gentamycin ototoxicity.
    The Journal of the Association of Physicians of India, 1988, Volume: 36, Issue:2

    Topics: Adolescent; Bacterial Infections; Deafness; Gentamicins; Humans; Male; Meningitis

1988
[Deafness and gentallin].
    JFORL. Journal francais d'oto-rhino-laryngologie; audiophonologie et chirurgie maxillo-faciale, 1972, Volume: 21, Issue:4

    Topics: Adult; Audiometry; Cochlea; Deafness; Ear, Inner; Female; Gentamicins; Humans; Kidney Failure, Chron

1972
[Gentamicin and auricular toxicity].
    Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 1969, Volume: 86, Issue:9

    Topics: Adult; Animals; Audiometry; Deafness; Ear Diseases; Ear, Inner; Female; Gentamicins; Guinea Pigs; Hi

1969
Untoward effects of antimicrobial agents on major organ systems.
    The Medical clinics of North America, 1974, Volume: 58, Issue:3

    Topics: Agranulocytosis; Amphotericin B; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Ataxia;

1974
Neomycin toxicity from porcine skin xenografts.
    Annals of surgery, 1974, Volume: 179, Issue:2

    Topics: Aged; Animals; Burns; Chromatography, Paper; Deafness; Ear; Female; Gentamicins; Humans; Kidney; Kid

1974
Drug-induced deafness.
    JAMA, 1973, Apr-23, Volume: 224, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Aspirin; Deafness; Drug-Related Side Effects and Adverse Reactions; Et

1973
[Gentamicin and deafness].
    Acta oto-rino-laringologica ibero-americana, 1973, Volume: 24, Issue:2

    Topics: Cochlea; Deafness; Drug Evaluation; Gentamicins; Humans; Otitis; Pharyngitis

1973
Multiple bone lesions caused by Avian-Battey mycobacteria. Report of a case.
    The Journal of bone and joint surgery. British volume, 1974, Volume: 56, Issue:2

    Topics: Adolescent; Animals; Antitubercular Agents; Birds; Clavicle; Clofazimine; Deafness; Frontal Bone; Ge

1974
Neurologic complications of malignant external otitis.
    Neurology, 1971, Volume: 21, Issue:11

    Topics: Abducens Nerve; Aged; Carbenicillin; Cranial Nerves; Deafness; Diabetes Complications; Facial Paraly

1971
[Deafness and equilibrium disorders caused by gentamicin].
    Nederlands tijdschrift voor geneeskunde, 1972, Jul-22, Volume: 116, Issue:30

    Topics: Adult; Deafness; Female; Gentamicins; Humans; Labyrinth Diseases; Male; Middle Aged

1972
Strial atrophy in clinical and experimental deafness.
    The Laryngoscope, 1972, Volume: 82, Issue:7

    Topics: Animals; Atrophy; Basement Membrane; Blood Vessels; Cochlea; Deafness; Dogs; Ethacrynic Acid; Gentam

1972
Clinical research experience with gentamicin. Incidence of adverse reactions.
    The Medical journal of Australia, 1970, Jun-13, Volume: 1

    Topics: Deafness; Gentamicins; Hearing Disorders; Humans; Kanamycin; Kidney Diseases; Male; Middle Aged; Neo

1970
[Acute deafness after gentamycin treatment of anuria].
    HNO, 1969, Volume: 17, Issue:9

    Topics: Acute Disease; Acute Kidney Injury; Adult; Anuria; Deafness; Ear, Inner; Electrophysiology; Gentamic

1969
A case of gentamicin accentuated hearing loss.
    The Journal of laryngology and otology, 1968, Volume: 82, Issue:9

    Topics: Adult; Audiometry; Deafness; Gentamicins; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Str

1968