gentamicin has been researched along with Creutzfeldt-Jakob Syndrome in 1 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Creutzfeldt-Jakob Syndrome: A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
| Excerpt | Relevance | Reference |
|---|---|---|
| " Based on previous findings that tetracyclines revert abnormal physicochemical properties and abolish neurotoxicity of PrP peptides in vitro, we tested the ability of these compounds to interact with PrP(Sc) from patients with the new variant of Creutzfeldt-Jakob disease (vCJD) and cattle with bovine spongiform encephalopathy (BSE)." | 3.71 | Tetracyclines affect prion infectivity. ( Angeretti, N; Awan, T; Bertani, I; Bugiani, O; Caramelli, M; Colombo, L; Farina, L; Forloni, G; Giaccone, G; Girola, L; Grazia Bruzzone, M; Ironside, JW; Iussich, S; Limido, L; Poli, G; Rossi, G; Salmona, M; Tagliavini, F, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Forloni, G | 1 |
| Iussich, S | 1 |
| Awan, T | 1 |
| Colombo, L | 1 |
| Angeretti, N | 1 |
| Girola, L | 1 |
| Bertani, I | 1 |
| Poli, G | 1 |
| Caramelli, M | 1 |
| Grazia Bruzzone, M | 1 |
| Farina, L | 1 |
| Limido, L | 1 |
| Rossi, G | 1 |
| Giaccone, G | 1 |
| Ironside, JW | 1 |
| Bugiani, O | 1 |
| Salmona, M | 1 |
| Tagliavini, F | 1 |
1 other study available for gentamicin and Creutzfeldt-Jakob Syndrome
| Article | Year |
|---|---|
Tetracyclines affect prion infectivity.
Topics: Animals; Anti-Bacterial Agents; Brain; Cattle; Creutzfeldt-Jakob Syndrome; Cricetinae; Disease Model | 2002 |