Page last updated: 2024-10-27

gentamicin and Conjugate Nystagmus

gentamicin has been researched along with Conjugate Nystagmus in 17 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
"To determine if a protocol of weekly intratympanic gentamicin injections administered until development of signs of unilateral vestibular hypofunction can alleviate vertigo while preserving hearing in patients with intractable vertigo caused by unilateral Meniere's disease."9.09Intratympanic gentamicin for control of vertigo in Meniere's disease: vestibular signs that specify completion of therapy. ( Minor, LB, 1999)
"To look for factors relating to the vertigo control and hearing changes after intratympanic injections of gentamicin (GM)."7.73Factors relating to the vertigo control and hearing changes following intratympanic gentamicin for intractable Ménière's disease. ( Fukushima, M; Horii, A; Kitahara, T; Kizawa, K; Kubo, T; Masumura, C; Mitani, K; Nakagawa, A; Nishiike, S; Nishimura, M; Saika, T; Sasaki, T; Uno, A, 2006)
"To determine if a protocol of weekly intratympanic gentamicin injections administered until development of signs of unilateral vestibular hypofunction can alleviate vertigo while preserving hearing in patients with intractable vertigo caused by unilateral Meniere's disease."5.09Intratympanic gentamicin for control of vertigo in Meniere's disease: vestibular signs that specify completion of therapy. ( Minor, LB, 1999)
"To look for factors relating to the vertigo control and hearing changes after intratympanic injections of gentamicin (GM)."3.73Factors relating to the vertigo control and hearing changes following intratympanic gentamicin for intractable Ménière's disease. ( Fukushima, M; Horii, A; Kitahara, T; Kizawa, K; Kubo, T; Masumura, C; Mitani, K; Nakagawa, A; Nishiike, S; Nishimura, M; Saika, T; Sasaki, T; Uno, A, 2006)
"Gentamicin ototoxicity presents with gait imbalance and oscillopsia, but only rarely with hearing loss and vertigo."3.73Gentamicin ototoxicity: clinical features and the effect on the human vestibulo-ocular reflex. ( Baloh, RW; Ishiyama, A; Ishiyama, G; Kerber, K, 2006)
"Five patients with Menière's disease and disabling vertigo were treated with two intratympanic instillations of gentamicin given at an interval of about 12 h."3.68Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy. ( Magnusson, M; Padoan, S, 1991)
"Gentamicin has a well-known potential for damaging the peripheral vestibular organs."1.72Central nystagmus and alterations in vestibular tests due to an inadvertent gentamicin administration into spinal space: A CARE case report. ( Breinbauer, HA; Delano, PH; Eyzaguirre, M; Herrero, D, 2022)
"Patients with vestibular neurolabyrinthitis showed deviation of SVH toward the affected side-down at the early stage after the attack, irrespective of VEMP results."1.34Does acute dysfunction of the saccular afferents affect the subjective visual horizontal in patients with vestibular neurolabyrinthitis? ( Iwasaki, S; Murofushi, T; Sugasawa, K; Takai, Y; Ushio, M, 2007)
"Twelve patients with unilateral Meniere's disease were treated and prospectively studied."1.29Irritative spontaneous nystagmus following intratympanic gentamicin for Menière's disease. ( Parnes, LS; Riddell, D, 1993)
"Dibekacin-treated animals showed a significant (P less than 0."1.27Comparative ototoxicity of dibekacin and netilmicin in guinea pigs. ( Arpini, A; Forlani, A; Marzanatti, M; Parravicini, L, 1983)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19905 (29.41)18.7374
1990's5 (29.41)18.2507
2000's4 (23.53)29.6817
2010's1 (5.88)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Breinbauer, HA1
Eyzaguirre, M1
Herrero, D1
Delano, PH1
Ciacca, G1
Di Giovanni, A1
Califano, L1
Pettorossi, VE1
Ricci, G1
Pelliccia, C1
Faralli, M1
Reynard, P1
Karkas, A1
Gavid, M1
Lelonge, Y1
Bertholon, P1
Carey, JP1
Minor, LB2
Peng, GC1
Della Santina, CC1
Cremer, PD1
Haslwanter, T1
Horii, A1
Saika, T1
Uno, A1
Nishiike, S1
Mitani, K1
Nishimura, M1
Kitahara, T1
Fukushima, M1
Nakagawa, A1
Masumura, C1
Sasaki, T1
Kizawa, K1
Kubo, T1
Ishiyama, G1
Ishiyama, A1
Kerber, K1
Baloh, RW1
Murofushi, T1
Ushio, M1
Takai, Y1
Iwasaki, S1
Sugasawa, K1
Parravicini, L1
Forlani, A1
Marzanatti, M1
Arpini, A1
Eviatar, L1
Eviatar, A1
Parnes, LS1
Riddell, D1
Yen, MT1
Herdman, SJ1
Tusa, RJ1
Magnusson, M2
Padoan, S2
Karlberg, M1
Johansson, R1
Nordström, L2
Banck, G2
Belfrage, S2
Juhlin, I2
Tjernström, O2
Toremalm, NG2
Federspil, P1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Gentamicin Treatment Prior to Vestibular Schwannoma Surgery in Patients With Definite Remaining Vestibular Function[NCT02379754]Phase 40 participants (Actual)Interventional2015-01-31Withdrawn
Gentamicin Treatment Prior to Vestibular Schwannoma Surgery in Patients With no Measurable Remaining Vestibular Function[NCT02415257]Phase 40 participants (Actual)Interventional2015-04-30Withdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for gentamicin and Conjugate Nystagmus

ArticleYear
Intratympanic gentamicin for control of vertigo in Meniere's disease: vestibular signs that specify completion of therapy.
    The American journal of otology, 1999, Volume: 20, Issue:2

    Topics: Adult; Aged; Caloric Tests; Clinical Protocols; Ear, Inner; Female; Gentamicins; Hearing Disorders;

1999

Other Studies

16 other studies available for gentamicin and Conjugate Nystagmus

ArticleYear
Central nystagmus and alterations in vestibular tests due to an inadvertent gentamicin administration into spinal space: A CARE case report.
    European annals of otorhinolaryngology, head and neck diseases, 2022, Volume: 139, Issue:4

    Topics: Bilateral Vestibulopathy; Gentamicins; Humans; Male; Middle Aged; Nystagmus, Pathologic; Vertigo; Ve

2022
Skull-vibration-induced nystagmus test in patients who are candidates for intratympanic gentamicin injection.
    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2023, Volume: 43, Issue:2

    Topics: Anti-Bacterial Agents; Gentamicins; Humans; Injection, Intratympanic; Nystagmus, Pathologic; Retrosp

2023
Delayed endolymphatic hydrops. Special emphasis on nystagmus associated with episodes and contribution of chemical labyrinthectomy.
    European annals of otorhinolaryngology, head and neck diseases, 2018, Volume: 135, Issue:5

    Topics: Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Deafness; Endolymphatic Hydrops; Female; Gentamic

2018
Changes in the three-dimensional angular vestibulo-ocular reflex following intratympanic gentamicin for Ménière's disease.
    Journal of the Association for Research in Otolaryngology : JARO, 2002, Volume: 3, Issue:4

    Topics: Adult; Aged; Cold Temperature; Female; Gentamicins; Head; Humans; Male; Meniere Disease; Middle Aged

2002
Factors relating to the vertigo control and hearing changes following intratympanic gentamicin for intractable Ménière's disease.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2006, Volume: 27, Issue:6

    Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Evoked Response; Female; Gentamicins; Hearing Loss;

2006
Gentamicin ototoxicity: clinical features and the effect on the human vestibulo-ocular reflex.
    Acta oto-laryngologica, 2006, Volume: 126, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Gentamicins; Head Movements; Humans;

2006
Does acute dysfunction of the saccular afferents affect the subjective visual horizontal in patients with vestibular neurolabyrinthitis?
    Acta oto-laryngologica. Supplementum, 2007, Issue:559

    Topics: Adult; Aged; Anti-Bacterial Agents; Electromyography; Evoked Potentials; Female; Gentamicins; Humans

2007
Comparative ototoxicity of dibekacin and netilmicin in guinea pigs.
    Acta pharmacologica et toxicologica, 1983, Volume: 53, Issue:3

    Topics: Action Potentials; Animals; Auditory Threshold; Cochlea; Dibekacin; Evoked Potentials, Auditory; Fem

1983
Development of head control and vestibular responses in infants treated with aminoglycosides.
    Developmental medicine and child neurology, 1982, Volume: 24, Issue:3

    Topics: Cerebral Palsy; Female; Follow-Up Studies; Gentamicins; Humans; Infant; Infant, Newborn; Infant, Pre

1982
Irritative spontaneous nystagmus following intratympanic gentamicin for Menière's disease.
    The Laryngoscope, 1993, Volume: 103, Issue:7

    Topics: Adult; Aged; Ear, Inner; Ear, Middle; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Age

1993
Oscillopsia and pseudonystagmus in kidney transplant patients.
    American journal of ophthalmology, 1999, Volume: 128, Issue:6

    Topics: Adult; Eye Movements; Female; Gentamicins; Head Movements; Humans; Kidney Transplantation; Male; Mid

1999
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease.
    Acta oto-laryngologica. Supplementum, 1991, Volume: 481

    Topics: Adult; Gentamicins; Hearing Disorders; Humans; Meniere Disease; Middle Aged; Nystagmus, Pathologic;

1991
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
    Acta oto-laryngologica, 1991, Volume: 111, Issue:4

    Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease;

1991
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
    Acta oto-laryngologica, 1991, Volume: 111, Issue:4

    Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease;

1991
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
    Acta oto-laryngologica, 1991, Volume: 111, Issue:4

    Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease;

1991
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
    Acta oto-laryngologica, 1991, Volume: 111, Issue:4

    Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease;

1991
Prospective study of the ototoxicity of gentamicin.
    Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology, 1973

    Topics: Adult; Age Factors; Aged; Creatinine; Electrooculography; Gentamicins; Hearing Disorders; Humans; Ki

1973
The ototoxicity of gentamicin.
    Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology, 1973

    Topics: Age Factors; Aged; Body Temperature; Cochlea; Creatinine; Electrooculography; Female; Gentamicins; H

1973
[Experimental studies on decreasing Streptomyces antibiotic ototoxicity by dividing the daily dosage].
    Zeitschrift fur Laryngologie, Rhinologie, Otologie und ihre Grenzgebiete, 1972, Volume: 51, Issue:11

    Topics: Animals; Body Weight; Cochlea; Gentamicins; Guinea Pigs; Hearing Disorders; Hearing Tests; Injection

1972