Page last updated: 2024-10-27

gentamicin and Chronic Kidney Failure

gentamicin has been researched along with Chronic Kidney Failure in 135 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
"We advocate initial treatment of PD peritonitis with non-vancomycin-based therapy given similar efficacy and the potential for reduction of resistant organisms."9.11Efficacy of a non-vancomycin-based peritoneal dialysis peritonitis protocol. ( Gock, H; Langham, R; Mullins, K; Murphy, B; Snider, J; Toussaint, N, 2005)
"Bacterial peritonitis is a well-recognized complication of chronic ambulatory peritoneal dialysis (CAPD) in patients with end-stage renal failure."5.33Ciprofloxacin treatment of bacterial peritonitis associated with chronic ambulatory peritoneal dialysis caused by Neisseria cinerea. ( Anijeet, H; Corkill, JE; Parry, CM; Saxena, R; Taegtmeyer, M, 2006)
" We studied the possible protective effect of the antioxidant N-acetylcysteine (NAC) in gentamicin-induced hearing loss in hemodialysis patients."5.12Gentamicin-induced ototoxicity in hemodialysis patients is ameliorated by N-acetylcysteine. ( Abramsohn, R; Averbukh, Z; Efrati, S; Eviatar, E; Feldman, L; Gersch, E; Weissgarten, J; Yarovoy, I, 2007)
"The practice of locking newly inserted tunneled central venous catheters with gentamicin and heparin is an effective strategy to reduce line sepsis rates, and is associated with beneficial effects on epoetin requirements."5.11Locking of tunneled hemodialysis catheters with gentamicin and heparin. ( Fluck, RJ; Hulme, LJ; McIntyre, CW; Taal, M, 2004)
"We advocate initial treatment of PD peritonitis with non-vancomycin-based therapy given similar efficacy and the potential for reduction of resistant organisms."5.11Efficacy of a non-vancomycin-based peritoneal dialysis peritonitis protocol. ( Gock, H; Langham, R; Mullins, K; Murphy, B; Snider, J; Toussaint, N, 2005)
"The aim of this study was to describe the safety profile and pharmacokinetic/pharmacodynamic parameters in end-stage renal disease patients who received gentamicin as empirical treatment in catheter-related bacteremia when they showed infection signs, regardless of the timing of the next HD."3.91Gentamicin as Empirical Treatment in Hemodialysis Patients: Safety, Pharmacokinetics, and Pharmacodynamics. ( Camacho-Martínez, P; Gil-Navarro, MV; Gil-Sacaluga, L; Guisado-Gil, AB; Herrera-Hidalgo, L; Lepe-Jiménez, JA; Molina, J; Santos-Rubio, MD, 2019)
" In this nested case-control study, independent AKI risk factors were vancomycin coadministration, high AG trough levels and heart failure."3.81Acute Kidney Injury and Renal Recovery with the Use of Aminoglycosides: A Large Retrospective Study. ( Ammann, H; Bernier-Jean, A; Bouchard, J; Brunette, V; Lavergne, V; Paquette, F; Pichette, V; Troyanov, S, 2015)
"A 65-year-old man with end-stage renal disease on continuous ambulatory peritoneal dialysis accidentally received an acute massive overdose of gentamicin as a treatment of peritonitis."3.69Acute massive gentamicin intoxication in a patient with end-stage renal disease. ( James, SH; Lien, YH; Lu, CM, 1996)
"A prospective study was undertaken of 10 chronic renal failure patients on Continuous Ambulatory Peritoneal Dialysis (CAPD) complicated by repeated bouts of peritonitis treated with gentamicin."3.68Gentamicin ototoxicity in continuous ambulatory peritoneal dialysis. ( Aziz, NS; Gendeh, BS; Gibb, AG; Kong, N; Said, H; Zahir, ZM, 1993)
"Interstitial nephritis with acute renal failure was observed in 5 cases out of 6 treated by the association of methicillin and gentamycin, wheras no case, was observed when each of these antibodies was used separately."3.65[The nephrotoxicity of the methicillin-gentamycin combination. Apropos of 5 cases]. ( Becq-Giraudon, B; Pourrat, O; Sudre, Y; Yver, L, 1976)
" Predialysis every-other-day dosing may be recommended during SDHD."2.77Gentamicin pharmacokinetics and pharmacodynamics during short-daily hemodialysis. ( Chambers, M; Decker, BS; Kraus, MA; Moe, SM; Mohamed, AN; Sowinski, KM, 2012)
" But the safety of long-term use of antimicrobial lock still needs to be defined."2.74Successful prevention of cuffed hemodialysis catheter-related infection using an antibiotic lock technique by strictly catheter-restricted antibiotic lock solution method. ( Chen, J; Lv, R; Tan, H; Yuan, J; Zhang, P, 2009)
"Thrombosis was defined as the inability to use catheter at a blood flow of 200 ml/min despite intraluminal thrombolysis."2.72Tunneled catheters' outcome optimization among diabetics on dialysis through antibiotic-lock placement. ( Abu-Oun, BA; Al-Ghamdi, AA; Al-Hafiz, A; Hussain, SM; Naguib, M; Panhotra, BR; Saxena, AK; Sundaram, DS; Venkateshappa, CK, 2006)
"The aim of this study was to evaluate dosing schedules of gentamicin in patients with end-stage renal disease and receiving hemodialysis."2.72Dosing of gentamicin in patients with end-stage renal disease receiving hemodialysis. ( Dang, L; Duffull, S; Johnson, DW; Teigen, MM, 2006)
" Pharmacokinetic parameters were calculated assuming a one-compartment model."2.71Gentamicin pharmacokinetics during slow daily home hemodialysis. ( Bailie, GR; Bender, WL; Manley, HJ; McClaran, ML, 2003)
"Gentamicin use was a significant predictor of lower peritonitis rates (relative risk, 0."2.71Randomized, double-blind trial of antibiotic exit site cream for prevention of exit site infection in peritoneal dialysis patients. ( Bender, F; Bernardini, J; Florio, T; Fried, L; Palmmontalbano, L; Piraino, B; Sloand, J, 2005)
" The results of this study suggest that no additional dosage adjustment of isepamicin during concomitant therapy with piperacillin in hemodialysis patients is necessary."2.67Effect of concomitant administration of piperacillin on the dispositions of isepamicin and gentamicin in patients with end-stage renal disease. ( Affrime, MB; Awni, WM; Halstenson, CE; Heim-Duthoy, KL; Herman, CS; Keane, WF; Kelloway, JH; Teal, MA; Wong, MO, 1992)
"The subsequent recurrence rate of peritonitis following CAPD catheter replacement (5%) was significantly less than after urokinase (41%) (p less than 0."2.66Tenckhoff catheter replacement or intraperitoneal urokinase: a randomised trial in the management of recurrent continuous ambulatory peritoneal dialysis (CAPD) peritonitis. ( Boletis, I; Brown, CB; Cohen, GL; el Nahas, AM; Johnson, BF; Moorhead, PJ; Raftery, AT; Williams, AJ, 1989)
"Gentamicin was inactivated to a greater extent by carbenicillin than by piperacillin (P less than 0."2.65Gentamicin inactivation by piperacillin or carbenicillin in patients with end-stage renal disease. ( Atkin-Thor, E; Matsen, JM; Russo, ME; Saxon, BJ; Thompson, MI, 1982)
"Drug-induced myoclonus is a diagnosis of exclusion."2.48Gentamicin-induced myoclonus: a case report and literature review of antibiotics-induced myoclonus. ( Panichpisal, K; Sarva, H, 2012)
" The purpose of this paper is to review the concepts pertinent to drug removal by hemodialysis and discuss the issues related to these new dialysis techniques and how they may have a impact on drug removal and the design of dosing regimens."2.44Drug dosing considerations in alternative hemodialysis. ( Decker, BS; Mueller, BA; Sowinski, KM, 2007)
"Pseudomonas peritonitis is a serious complication of peritoneal dialysis (PD)."1.48Peritoneal dialysis-related peritonitis caused by Pseudomonas species: Insight from a post-millennial case series. ( Chow, KM; Kwan, BC; Leung, CB; Li, PK; Lu, W; Pang, WF; Szeto, CC, 2018)
"Our study supports the original FDA label with regard to the dosing regimen of gentamicin in ESRD patients, which offers adequate clinical benefit as well as an acceptable safety profile."1.43Gentamicin dosing strategy in patients with end-stage renal disease receiving haemodialysis: evaluation using a semi-mechanistic pharmacokinetic/pharmacodynamic model. ( Derendorf, H; He, Y; Liu, Y; Sy, SK; Xia, H; Zhuang, L, 2016)
"Diabetic nephropathy is one of the leading causes of end-stage renal disease (ESRD)."1.35Pharmacokinetics of gentamicin in hemodialysis patients: a comparative study between diabetic and non-diabetic patients. ( Al-Homrany, MA; El Sherif, AK; Irshaid, YM; Omar, HA, 2009)
"We report a pneumonia in a patient with chronic renal failure, who had chronic rejection of transplanted kidney."1.33A case of pneumonia caused by Ewingella americana in a patient with chronic renal failure. ( Ha, JS; Jeon, DS; Kim, HC; Kim, JR; Ryoo, NH, 2005)
"Peritonitis is a major complication of peritoneal dialysis (PD)."1.33Mycobacterium simiae: a previously undescribed pathogen in peritoneal dialysis peritonitis. ( Jeyaratnam, D; Keenan, N; Sheerin, NS, 2005)
" Analysis included pharmacokinetic parameters in stage 5 CKD, ARF, impact of the dialysis prescription, and treatment results of individualized dosing regimens lasting more than 4 days."1.33Aminoglycosides in intermittent hemodialysis: pharmacokinetics with individual dosing. ( Dager, WE; King, JH, 2006)
"The aim of this study was to ascertain the most suitable dosing schedule for gentamicin in patients receiving hemodialysis."1.33Development of a semimechanistic model to describe the pharmacokinetics of gentamicin in patients receiving hemodialysis. ( Dang, L; Duffull, S, 2006)
"Bacterial peritonitis is a well-recognized complication of chronic ambulatory peritoneal dialysis (CAPD) in patients with end-stage renal failure."1.33Ciprofloxacin treatment of bacterial peritonitis associated with chronic ambulatory peritoneal dialysis caused by Neisseria cinerea. ( Anijeet, H; Corkill, JE; Parry, CM; Saxena, R; Taegtmeyer, M, 2006)
" All of the pharmacokinetic parameters of interest were determined using Bayesian pharmacokinetic procedures and only two plasma gentamicin concentrations."1.32Bayesian pharmacokinetics of gentamicin in a haemodialysis population. ( Ariano, RE; Vercaigne, LM; Zacharias, JM, 2004)
"multocida peritonitis have been reported in adults."1.30Pasteurella multocida peritonitis in patients undergoing peritoneal dialysis. ( Loghman-Adham, M, 1997)
"4 mg, whereas the intradialytic gentamicin half-life was 2."1.30Characterization of gentamicin pharmacokinetics in patients hemodialyzed with high-flux polysulfone membranes. ( Amin, NB; Anandan, JV; Dunfee, TP; Padhi, ID; Patel, RV; Touchette, MA, 1999)
" These data indicate that dosage adjustments are necessary in subjects with decreased renal function."1.28Isepamicin disposition in subjects with various degrees of renal function. ( Affrime, MB; Awni, WM; Halstenson, CE; Kelloway, JS; Lin, CC; Shapiro, BE; Teal, MA, 1991)
"Gentamicin is well known to be a cause of vestibular toxicity."1.28Vestibular toxicity due to gentamicin in peritoneal dialysis patients. ( Bernardini, J; Chong, TK; Piraino, B, 1991)
"Eighteen patients with chronic renal failure of diverse causes were followed from initiation of the CAPD program since January 1981 until June 1988."1.28[Peritonitis in continuous ambulatory peritoneal dialysis. Microbiological and clinical evaluation]. ( Abalo, AB; Prado, A; Predari, SC; Ribas, CM; Santoianni, JE; Zucchini, A, 1990)
"A third patient with chronic renal failure acquired A hydrophila pneumonia at home and quickly died from the infection."1.26Pneumonia and bacteremia due to Aeromonas hydrophila. ( Cook, FV; Reines, HD, 1981)
" This relationship provides a basis for formulating gentamicin dosage in pediatric patients with renal failure."1.26Determining gentamicin dosage in infants and children with renal failure. ( McCracken, GH; Nelson, JD; Sirinavin, S, 1980)
" Dosage of gentamicin sulfate was 1."1.26Vestibular toxicity of gentamicin. Incidence in patients receiving long-term hemodialysis therapy. ( Dominguez-Moreno, M; Gailiunas, P; Gottlieb, MN; Lazarus, M; Lowrie, EG; Merrill, JP, 1978)
" The kinetic model developed can be used to determine gentamicin dosing for hemodialysis patients and to determine an average elimination rate constant for a given dialysis apparatus."1.26Prediction of serum gentamicin concentrations in patients undergoing hemodialysis. ( Bloom, P; Goetz, DR; Hoag, S; Pancorbo, S, 1980)
"Fifty-seven cancer patients, who had had an 8--15% loss of body weight in the previous 6 months, were studied to establish the reliabity in wasted individuals of presently available nomograms correlating serum creatinine with creatinine clearance."1.26Nephrotoxic antibiotics in patients with renal failures: guidelines for debilitated patients. ( Carlon, GC; Colaco, FM; Goldiner, PL; Howland, WS; Scheiner, E, 1979)
" As a first step in the study of the effects of renal insufficiency and the anephric state on the pharmacokinetic parameters of gentamicin, serum and urine levels of this drug were studied after a single intravenous bolus dose during hemodialysis in patients suffering from chronic renal failure."1.26Gentamicin pharmacokinetics during hemodialysis in patients suffering from chronic renal failure. ( Daigneault, R; Lapierre, L; Létourneau-Saheb, L; Prud'Homme, M; Serois, G; St-Louis, G, 1977)
"Reversible acute renal failure was observed in 13 patients after combined antibiotic therapy using gentamicin."1.26[Nephrotoxicity of gentamicin. Conditions for the use of this antibiotic in the elderly and in the patient with renal insufficiency]. ( Ganeval, D; Jungers, P; Kleinknecht, D, 1977)
" The results indicate that gentamicin requirements are underestimated by methods currently employed to calculate dosage for patients with renal failure who receive carbenicillin concurrently."1.26Inactivation of gentamicin by penicillins in patients with renal failure. ( Bullock, WE; Ervin, FR; Nuttall, CE, 1976)
"Carbenicillin appears to produce clinically important inactivation of aminoglycoside antibiotics in patients with severe renal failure."1.26Carbenicillin inactivation of aminoglycosides in patients with severe renal failure. ( Keane, W; Shapiro, F; Weibert, R, 1976)
"A pharmacokinetic study of netilmicin was conducted in 12 healthy subjects and 24 subjects with chronic renal failure."1.26Pharmacokinetics of netilmicin in the presence of normal or impaired renal function. ( Fillastre, JP; Humbert, G; Leroy, A; Oksenhendler, G, 1978)
"Gentamicin treatment in patients with grossly decreased renal function should thus be performed under control of serum levels."1.26[Is endogenous creatinine clearance a sound basis for estimation of elimination half life of gentamicin?]. ( Graninger, W; Hitzenberger, G; Jaschek, I; Rameis, H, 1980)
"Netilmicin serum levels were within expected values."1.26Prophylactic netilmicin in surgery. ( Abbas, AM; Jones, RB; Rigby, CC; Zaman, MM, 1982)
" Recent studies have emphasized the dubious accuracy of commonly used formulas, and computer programs that provide pharmacokinetic data for individual patients from multiple blood samples have helped to adjust dosages but are expensive."1.26Gentamicin: use of a programmable calculator to determine dosages from pharmacokinetic data for individual patients. ( Courchesne, Y; de Repentigny, L; Dumont, L; Larochelle, P; Le Lorier, J; Morisset, R, 1981)
" Subsequent clearance of gentamicin from the serum occurred slowly with an elimination half-life of 36 h."1.26Pharmacokinetics of gentamicin in patients undergoing continuous ambulatory peritoneal dialysis. ( Comty, C; Pancorbo, S, 1981)
"Cephaloridine has some renal toxic effects in high concentration; in the renal failure it is advisable to calculate the exact dose of the antibiotic by the use of nomograms when the creatinine clearance is known."1.25[Antibiotic therapy and renal insufficiency. Pharmacokinetics of pivampicillin, cephaloridin and streptomycin in chronic uremic patients undergoing conservative or hemodialytic treatment]. ( Bertoli, M; Campanacci, L; Cancarini, GC; Huber, W; Toigo, G, 1975)
" time profiles of various dosage regimens recommended for renal impairment were reassessed by applying pharmacokinetic techniques to the patient data in the clinical literature."1.25Practical pharmacokinetic techniques for drug consultation and evaluation. IV: Gentamicin blood level versus time profiles of various dosage regimens recommended for renal impairment. ( Schumacher, GE, 1975)

Research

Studies (135)

TimeframeStudies, this research(%)All Research%
pre-199080 (59.26)18.7374
1990's15 (11.11)18.2507
2000's27 (20.00)29.6817
2010's13 (9.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lu, W1
Kwan, BC1
Chow, KM2
Pang, WF1
Leung, CB2
Li, PK2
Szeto, CC2
Guisado-Gil, AB1
Herrera-Hidalgo, L1
Santos-Rubio, MD1
Gil-Sacaluga, L1
Molina, J1
Lepe-Jiménez, JA1
Camacho-Martínez, P1
Gil-Navarro, MV1
Kwan, C1
Chen, O1
Radionova, S1
Sadiq, A1
Moskovits, M1
Paquette, F1
Bernier-Jean, A1
Brunette, V1
Ammann, H1
Lavergne, V1
Pichette, V1
Troyanov, S1
Bouchard, J1
Zhuang, L1
He, Y1
Xia, H1
Liu, Y1
Sy, SK1
Derendorf, H1
Al-Homrany, MA1
Irshaid, YM1
El Sherif, AK1
Omar, HA1
Zhang, P1
Yuan, J1
Tan, H1
Lv, R1
Chen, J1
Polaschegg, HD1
Deschênes, G1
Allon, M1
Fitzgibbons, LN1
Puls, DL1
Mackay, K1
Forrest, GN1
Filiopoulos, V1
Hadjiyannakos, D1
Koutis, I1
Trompouki, S1
Micha, T1
Lazarou, D1
Vlassopoulos, D1
Castillo, RF1
Cañadas-De la Fuente, GA1
Husein-Elahmed, H1
Cantero-Hinojosa, J1
Pinner, NA1
Canada, RB1
Broyles, JE1
Hudson, JQ1
Decker, BS2
Mohamed, AN1
Chambers, M1
Kraus, MA1
Moe, SM1
Sowinski, KM2
Sarva, H1
Panichpisal, K1
Manley, HJ1
Bailie, GR1
McClaran, ML1
Bender, WL1
Wang, IK1
Chen, YM1
Chen, YC1
Fang, JT1
Hang, CC1
Karataş, Y1
Seçilmiş, MA1
Karayaylali, I1
Doran, F1
Büyükafşar, K1
Singirik, E1
Sagliker, Y1
Dikmen, A1
Vercaigne, LM1
Ariano, RE1
Zacharias, JM1
McIntyre, CW2
Hulme, LJ2
Taal, M2
Fluck, RJ2
Wang, Y1
Iwatani, H1
Ito, T1
Horimoto, N1
Yamato, M1
Matsui, I1
Imai, E1
Hori, M1
Lambie, SH1
Bernardini, J2
Bender, F1
Florio, T1
Sloand, J1
Palmmontalbano, L1
Fried, L1
Piraino, B2
Ryoo, NH1
Ha, JS1
Jeon, DS1
Kim, JR1
Kim, HC1
Keenan, N1
Jeyaratnam, D1
Sheerin, NS1
Toussaint, N1
Mullins, K1
Snider, J1
Murphy, B1
Langham, R1
Gock, H1
Dager, WE1
King, JH1
Dang, L2
Duffull, S2
Taegtmeyer, M1
Saxena, R1
Corkill, JE1
Anijeet, H1
Parry, CM1
Saxena, AK1
Panhotra, BR1
Sundaram, DS1
Al-Hafiz, A1
Naguib, M1
Venkateshappa, CK1
Abu-Oun, BA1
Hussain, SM1
Al-Ghamdi, AA1
Teigen, MM1
Johnson, DW1
Feldman, L1
Efrati, S1
Eviatar, E1
Abramsohn, R1
Yarovoy, I1
Gersch, E1
Averbukh, Z1
Weissgarten, J1
Al-Hwiesh, AK1
Abdul-Rahman, IS1
Molostvov, G1
James, S1
Fletcher, S1
Bennett, J1
Lehnert, H1
Bland, R1
Zehnder, D1
Mueller, BA1
Tepel, M1
Gabriel, R1
Valsamis, J1
Brauman, H1
Yourassowsky, E3
Mejia, G1
Leiderman, E1
Builes, M1
Henao, J1
Arbelaez, M1
Arango, JL1
Borrero, J1
Thompson, MI1
Russo, ME1
Saxon, BJ1
Atkin-Thor, E1
Matsen, JM1
Takasugi, M1
Hasegawa, O1
Soejima, M1
Yu, K1
Muta, T1
Matsuura, K1
Nakashima, Y1
Kuroiwa, A1
Kunifuji, Y1
Nakamura, T1
Schulz, E1
Busse, FW1
Strasburger, C1
Herhahn, J1
Wood, WG1
Sack, K1
Matzke, GR1
Halstenson, CE3
Keane, WF2
Vogel, F1
Exner, M1
von Lilienfeld-Toal, H1
Cattelaens, N1
Eichelbaum, M1
Berry, PL1
Kearns, GL1
Brown, RD1
Ritschel, WA1
Thompson, GA1
McEnery, PT1
Ramsden, RT1
Ackrill, P1
Blair, DC1
Duggan, DO1
Schroeder, ET1
Abbas, AM1
Jones, RB1
Rigby, CC1
Zaman, MM1
Riviere, JE1
de Repentigny, L1
Dumont, L1
Le Lorier, J1
Morisset, R1
Larochelle, P1
Courchesne, Y1
Pancorbo, S2
Comty, C1
Reines, HD1
Cook, FV1
Crass, RE1
Sirinavin, S1
McCracken, GH1
Nelson, JD1
Goetz, DR1
Hoag, S1
Bloom, P1
Rameis, H1
Hitzenberger, G1
Jaschek, I1
Graninger, W1
Zurovsky, Y1
Haber, C1
Kuranari, M1
Nawata, T1
Sato, Y1
Sakata, T1
Kodama, Y1
Takeyama, M1
Gendeh, BS1
Said, H1
Gibb, AG1
Aziz, NS1
Kong, N1
Zahir, ZM1
Vijayvargiya, R1
Veis, JH1
Lu, CM1
James, SH1
Lien, YH1
Loghman-Adham, M1
Green, KM1
Lappin, DW1
Curley, JW1
de Carpentier, JP1
Amin, NB1
Padhi, ID1
Touchette, MA1
Patel, RV1
Dunfee, TP1
Anandan, JV1
Easom, A1
Fattal, O1
Deville, JG1
Wong, TY1
Wu, AK1
Wang, AY1
Lui, SF1
Cohen, HJ1
Rundles, RW1
Yver, L1
Becq-Giraudon, B1
Pourrat, O1
Sudre, Y1
Leroy, A2
Oksenhendler, G2
Fillastre, JP2
Humbert, G2
Bloomfield, SE1
David, DS1
Cheigh, JS1
Kim, Y1
White, RP1
Stenzel, KH1
Rubin, AL1
Gailiunas, P1
Dominguez-Moreno, M1
Lazarus, M1
Lowrie, EG1
Gottlieb, MN1
Merrill, JP1
Wright, JP1
Potgieter, PD1
Forder, AA1
Botha, P1
Brinkworth, G1
Elisha, G1
Ferguson, AD1
Kraft, D1
Lode, H1
Lindholm, T1
Vozeh, S1
Spring, P2
Wenk, M1
Follath, F1
Orłowski, T1
Wierzba, K1
Lazowski, J1
Lypka, A1
Rumpf, KW1
Rieger, J1
Doht, B1
Ansorg, R1
Scheler, F1
Carlon, GC1
Scheiner, E1
Colaco, FM1
Howland, WS1
Goldiner, PL1
Fossati, C1
Kröger, E1
Rohmann, H1
Osten, B1
Falkenhagen, U1
Létourneau-Saheb, L1
Lapierre, L1
Daigneault, R1
Prud'Homme, M1
St-Louis, G1
Serois, G1
Jungers, P1
Ganeval, D1
Kleinknecht, D1
Ervin, FR1
Bullock, WE1
Nuttall, CE1
Weibert, R1
Keane, W1
Shapiro, F1
Mazzei, T1
Paradiso, M1
Nicoletti, I1
Periti, P1
Königshausen, T1
Rosin, H1
Hagedorn, HJ1
Küppers, H1
Grabensee, B1
Schumacher, GE1
Campanacci, L1
Huber, W1
Bertoli, M1
Cancarini, GC1
Toigo, G1
Wong, MO1
Herman, CS1
Heim-Duthoy, KL1
Teal, MA2
Affrime, MB2
Kelloway, JH1
Awni, WM2
Lye, WC1
Lee, EJ1
Tan, CC1
Ishigami, M1
Eguchi, M1
Yabuki, S1
Kelloway, JS1
Lin, CC1
Shapiro, BE1
Chong, TK1
Thomson, AH1
Grant, AC1
Rodger, RS1
Hughes, RL1
Predari, SC1
Abalo, AB1
Santoianni, JE1
Prado, A1
Ribas, CM1
Zucchini, A1
Williams, AJ1
Boletis, I1
Johnson, BF1
Raftery, AT1
Cohen, GL1
Moorhead, PJ1
el Nahas, AM1
Brown, CB1
Sedman, AJ1
Molitoris, BA1
Nakata, LM1
Gal, J1
Houghton, DC1
English, J1
Bennett, WM1
Verpooten, GA1
Giuliano, RA1
Pattyn, VM1
Scharpé, SL1
De Broe, ME3
Catolico, MM1
Campbell, S1
Jones, WN1
Logan, JL1
Bourbouze, R1
Gluckman, JC1
Frantz, P1
Paraire, M1
Baumann, FC1
Luciani, J1
Percheron, F1
Legrain, M1
del Río Vázquez, A1
Lurie, A1
Ogilvie, M1
Gold, CH1
Meyer, AM1
Goldberg, B1
Martin, H1
Gadot, P1
Gignoux, B1
Debain, JJ1
Freyss, G1
Poulain, H1
Möhring, K1
Schüler, HW1
Stöhrer, M1
Christopher, TG1
Korn, D1
Blair, AD1
Forrey, AW2
O'Neill, MA1
Cutler, RE2
Thatcher, GN1
Höffler, D1
Lagrue, G1
Fournier, A1
Sugarbaker, PH1
Sabath, LD2
Morgan, AP1
Chan, RA1
Benner, EJ1
Hoeprich, PD1
Aboulker, P1
Lassner, J1
Bürgi, M1
Rosaschino, F1
Carnelli, V1
Bosco, U1
Simon, C1
Schmitt, E1
Malerczyk, V1
Arkenau, C1
Fabre, J1
de Werra, P1
Kaye, D1
Levison, ME1
Labovitz, ED1
Gary, NE1
Hyams, PJ2
Smithivas, T2
Matalon, R2
Katz, L1
Simberkoff, MS2
Rahal, JJ2
Dume, T1
Wetzels, E1
Herms, W1
Schröder, E1
Wahlig, H1
Casey, JI1
Ruch, PA1
Stumpf, LL1
Finland, M1
Winters, RE1
Litwack, KD1
Hewitt, WL1
Waldvogel, F1
Gyselynck, AM1
Fleet, WP1
Federspil, P1
von Oldershausen, HF1
Held, H1
Menz, HP1
Schmidinger, H1
Stephens, SD1
Gingell, JC1
Chisholm, GD1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective, Randomized, Controlled Trial Evaluating the Efficacy of a Lock-therapy With a Solution of Taurolidine/Citrate (TauroLock) vs Standard Saline Solution for the Primary Prevention of Catheter-related Infections (CLI) in Adult Patients Wtih a Non[NCT02279121]162 participants (Actual)Interventional2014-11-30Completed
Intradialytic Drug Removal by Short-daily Hemodialysis[NCT00596167]6 participants (Actual)Interventional2007-09-30Completed
Pharmacokinetics of Tobramycin Administered at the Beginning of Intermittent Hemodialysis Session[NCT03904836]Phase 111 participants (Actual)Interventional2019-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Intradialytic Clearance of Levofloxacin, Gentamicin and Vancomycin in Patients Receiving Short-daily Hemodialysis

"The intradialytic clearance of levofloxacin, gentamicin and vancomycin will be determined in patients receiving short-daily hemodialysis.~(Of important note, due to technical issues the levofloxacin data was not able to be used for the analysis. Only the gentamicin and vancomycin data was analyzed.)" (NCT00596167)
Timeframe: Serum concentrations for each drug will be determined from blood samples at 0 (pre-infusion), 30, 60 minutes (end of infusion).

Interventionml/min (Median)
Intravenous antibiotic (vancomycin)Intravenous antibiotic (gentamicin)
Intravenous Antibiotic (Vancomycin)7.27.6

Reviews

4 reviews available for gentamicin and Chronic Kidney Failure

ArticleYear
[Renal toxicity of drugs in the neonate].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2010, Volume: 17, Issue:6

    Topics: Abnormalities, Drug-Induced; Anti-HIV Agents; Bartter Syndrome; Fanconi Syndrome; Female; Gentamicin

2010
Gentamicin-induced myoclonus: a case report and literature review of antibiotics-induced myoclonus.
    The neurologist, 2012, Volume: 18, Issue:6

    Topics: Anti-Bacterial Agents; Cephalosporins; Female; Gentamicins; Humans; Kidney Failure, Chronic; Middle

2012
Drug dosing considerations in alternative hemodialysis.
    Advances in chronic kidney disease, 2007, Volume: 14, Issue:3

    Topics: Anti-Infective Agents, Urinary; Blood Urea Nitrogen; Dose-Response Relationship, Drug; Drug Administ

2007
[Chemo-antibiotics during the course of kidney insufficiency].
    La Clinica terapeutica, 1975, Apr-30, Volume: 73, Issue:2

    Topics: Ampicillin; Anti-Bacterial Agents; Antitubercular Agents; Carbenicillin; Cephalosporins; Chloramphen

1975

Trials

15 trials available for gentamicin and Chronic Kidney Failure

ArticleYear
Successful prevention of cuffed hemodialysis catheter-related infection using an antibiotic lock technique by strictly catheter-restricted antibiotic lock solution method.
    Blood purification, 2009, Volume: 27, Issue:2

    Topics: Adult; Aged; Catheter-Related Infections; Catheters, Indwelling; Female; Gentamicins; Heparin; Human

2009
Approaches to prolong the use of uncuffed hemodialysis catheters: results of a randomized trial.
    American journal of nephrology, 2011, Volume: 33, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anticoagulants; Catheter-Related Infections;

2011
Gentamicin pharmacokinetics and pharmacodynamics during short-daily hemodialysis.
    American journal of nephrology, 2012, Volume: 36, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Female; Gentamicins; Humans; Infusions, Intraven

2012
Gentamicin pharmacokinetics during slow daily home hemodialysis.
    Kidney international, 2003, Volume: 63, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Female; Gentamicins; Hemodialysis, Home; Humans; Injections, Int

2003
Locking of tunneled hemodialysis catheters with gentamicin and heparin.
    Kidney international, 2004, Volume: 66, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Anti-Bacterial Agents; Anticoagulants; Catheterization; Cros

2004
Randomized, double-blind trial of antibiotic exit site cream for prevention of exit site infection in peritoneal dialysis patients.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:2

    Topics: Administration, Topical; Adult; Aged; Analysis of Variance; Catheters, Indwelling; Confidence Interv

2005
Efficacy of a non-vancomycin-based peritoneal dialysis peritonitis protocol.
    Nephrology (Carlton, Vic.), 2005, Volume: 10, Issue:2

    Topics: Adult; Aged; Anti-Bacterial Agents; Cefazolin; Drug Resistance, Bacterial; Drug Therapy, Combination

2005
Tunneled catheters' outcome optimization among diabetics on dialysis through antibiotic-lock placement.
    Kidney international, 2006, Volume: 70, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections;

2006
Dosing of gentamicin in patients with end-stage renal disease receiving hemodialysis.
    Journal of clinical pharmacology, 2006, Volume: 46, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Area Under Curve; Drug Administra

2006
Gentamicin-induced ototoxicity in hemodialysis patients is ameliorated by N-acetylcysteine.
    Kidney international, 2007, Volume: 72, Issue:3

    Topics: Acetylcysteine; Administration, Oral; Aged; Aminoglycosides; Anti-Bacterial Agents; Antioxidants; Ba

2007
Successful prevention of tunneled, central catheter infection by antibiotic lock therapy using vancomycin and gentamycin.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2007, Volume: 18, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Catheterization, Central Venous; Drug Therapy, C

2007
Gentamicin inactivation by piperacillin or carbenicillin in patients with end-stage renal disease.
    Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:2

    Topics: Biotransformation; Carbenicillin; Drug Interactions; Drug Therapy, Combination; Gentamicins; Half-Li

1982
Gentamicin and penicillin in the treatment of severe respiratory infections.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Feb-10, Volume: 55, Issue:6

    Topics: Adult; Clinical Trials as Topic; Creatinine; Drug Therapy, Combination; Gentamicins; Humans; Infusio

1979
Effect of concomitant administration of piperacillin on the dispositions of isepamicin and gentamicin in patients with end-stage renal disease.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:9

    Topics: Adult; Gentamicins; Half-Life; Humans; Kidney Failure, Chronic; Piperacillin

1992
Tenckhoff catheter replacement or intraperitoneal urokinase: a randomised trial in the management of recurrent continuous ambulatory peritoneal dialysis (CAPD) peritonitis.
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 1989, Volume: 9, Issue:1

    Topics: Catheters, Indwelling; Female; Gentamicins; Humans; Infusions, Parenteral; Kidney Failure, Chronic;

1989

Other Studies

116 other studies available for gentamicin and Chronic Kidney Failure

ArticleYear
Peritoneal dialysis-related peritonitis caused by Pseudomonas species: Insight from a post-millennial case series.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Adult; Aged; Anti-Bacterial Agents; Ceftazidime; Drug Resistance, Bacterial; Female; Gentamicins; Hu

2018
Gentamicin as Empirical Treatment in Hemodialysis Patients: Safety, Pharmacokinetics, and Pharmacodynamics.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2019, Volume: 23, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Fema

2019
Echocardiography: a case of coronary sinus endocarditis.
    Echocardiography (Mount Kisco, N.Y.), 2014, Volume: 31, Issue:9

    Topics: Adult; Anti-Bacterial Agents; Ceftazidime; Coronary Sinus; Diagnosis, Differential; Endocarditis; Fe

2014
Acute Kidney Injury and Renal Recovery with the Use of Aminoglycosides: A Large Retrospective Study.
    Nephron, 2015, Volume: 131, Issue:3

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Aminoglycosides; Antineoplastic Agents; Case-Control S

2015
Gentamicin dosing strategy in patients with end-stage renal disease receiving haemodialysis: evaluation using a semi-mechanistic pharmacokinetic/pharmacodynamic model.
    The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:4

    Topics: Algorithms; Anti-Bacterial Agents; Bacterial Infections; Gentamicins; Humans; Kidney Failure, Chroni

2016
Pharmacokinetics of gentamicin in hemodialysis patients: a comparative study between diabetic and non-diabetic patients.
    International urology and nephrology, 2009, Volume: 41, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Diabetic Nephropathies; Female; Gentamicins; Humans; Kidney Failure, C

2009
Loss of catheter lock fluid is caused by hydraulic effects and not by diffusion.
    Blood purification, 2009, Volume: 28, Issue:3

    Topics: Adult; Aged; Catheter-Related Infections; Catheters, Indwelling; Female; Gentamicins; Heparin; Human

2009
Dialysis: Are prophylactic gentamicin catheter locks safe?
    Nature reviews. Nephrology, 2011, Volume: 7, Issue:1

    Topics: Anti-Bacterial Agents; Catheters, Indwelling; Drug Resistance, Bacterial; Gentamicins; Humans; Kidne

2011
Management of gram-positive coccal bacteremia and hemodialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2011, Volume: 57, Issue:4

    Topics: Anti-Bacterial Agents; Bacteremia; Catheters, Indwelling; Daptomycin; Drug Resistance, Bacterial; En

2011
Pyoderma gangrenosum developing over an arteriovenous fistula scar.
    Internal medicine journal, 2011, Volume: 41, Issue:5

    Topics: Abscess; Arteriovenous Shunt, Surgical; Betamethasone Valerate; Drug Therapy, Combination; Gentamici

2011
Evaluation of vancomycin and gentamicin dialysis clearance using in vivo and in vitro systems.
    Renal failure, 2012, Volume: 34, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Dialysis Solutions; Female; Genta

2012
Successful treatment of renal abscess with percutaneous needle aspiration in a diabetic patient with end stage renal disease undergoing hemodialysis.
    Renal failure, 2003, Volume: 25, Issue:4

    Topics: Abscess; Aged; Anti-Bacterial Agents; Biopsy, Fine-Needle; Ceftriaxone; Diabetes Mellitus, Type 2; D

2003
Effect of tempol (4-hydroxy tempo) on gentamicin-induced nephrotoxicity in rats.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Creatinine; Cyclic N-Oxides; Gentamicins; Kidne

2004
Bayesian pharmacokinetics of gentamicin in a haemodialysis population.
    Clinical pharmacokinetics, 2004, Volume: 43, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Bayes Theorem; Gentamicins; Gram-Negative Bacterial Infections;

2004
Fetal cells in mother rats contribute to the remodeling of liver and kidney after injury.
    Biochemical and biophysical research communications, 2004, Dec-17, Volume: 325, Issue:3

    Topics: Animals; Chimerism; Ethanol; Female; Fetus; Gentamicins; Kidney; Kidney Failure, Chronic; Liver; Liv

2004
Prospective study of gentamicin locking of tunnelled dialysis catheters: the effect on infection rates and CRP.
    Kidney international, 2005, Volume: 67, Issue:1

    Topics: C-Reactive Protein; Catheters, Indwelling; Gentamicins; Humans; Infection Control; Kidney Failure, C

2005
A case of pneumonia caused by Ewingella americana in a patient with chronic renal failure.
    Journal of Korean medical science, 2005, Volume: 20, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Ceftriaxone; Enterobacteriaceae; Enterobacteriaceae Infections; Gentam

2005
Mycobacterium simiae: a previously undescribed pathogen in peritoneal dialysis peritonitis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 45, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Amikacin; Amoxicillin; Antiretroviral Therapy, Highly

2005
Aminoglycosides in intermittent hemodialysis: pharmacokinetics with individual dosing.
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:1

    Topics: Acute Kidney Injury; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Comorbidity; Fema

2006
Development of a semimechanistic model to describe the pharmacokinetics of gentamicin in patients receiving hemodialysis.
    Journal of clinical pharmacology, 2006, Volume: 46, Issue:6

    Topics: Anti-Bacterial Agents; Area Under Curve; Female; Gentamicins; Humans; Kidney Failure, Chronic; Male;

2006
Ciprofloxacin treatment of bacterial peritonitis associated with chronic ambulatory peritoneal dialysis caused by Neisseria cinerea.
    Journal of clinical microbiology, 2006, Volume: 44, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Ciprofloxacin; Gentamicins; Humans; Kidney Failure, Chronic; Male; Nei

2006
Extracellular calcium-sensing receptor is functionally expressed in human artery.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:3

    Topics: Arteries; Calcium; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Gentamicins; Humans;

2007
N-Acetylcysteine in the prevention of ototoxicity.
    Kidney international, 2007, Volume: 72, Issue:3

    Topics: Acetylcysteine; Administration, Oral; Aminoglycosides; Anti-Bacterial Agents; Antioxidants; Bacterem

2007
Nephrotoxicity of aminoglycosides.
    Lancet (London, England), 1982, Aug-21, Volume: 2, Issue:8295

    Topics: Gentamicins; Humans; Kidney; Kidney Failure, Chronic

1982
Plasma beta 2 microglobulin as a means of predicting gentamicin serum concentrations.
    Antimicrobial agents and chemotherapy, 1980, Volume: 17, Issue:4

    Topics: Adult; Aged; beta 2-Microglobulin; Beta-Globulins; Body Weight; Child; Creatinine; Gentamicins; Glom

1980
Transmission of toxoplasmosis by renal transplant.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1983, Volume: 2, Issue:6

    Topics: Adult; Cephalothin; Female; Gentamicins; Graft Rejection; Humans; Kidney Failure, Chronic; Kidney Tr

1983
[Gentamicin pharmacokinetics during hemodialysis].
    Nihon Jinzo Gakkai shi, 1984, Volume: 26, Issue:11

    Topics: Adult; Female; Gentamicins; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Renal Dial

1984
[Serum gentamicin level after intratracheal application in ventilated patients with normal and reduced kidney function].
    Deutsche medizinische Wochenschrift (1946), 1983, Dec-23, Volume: 108, Issue:51-52

    Topics: Adult; Aged; Female; Gentamicins; Humans; Intubation, Intratracheal; Kidney Failure, Chronic; Male;

1983
Hemodialysis elimination rates and clearance of gentamicin and tobramycin.
    Antimicrobial agents and chemotherapy, 1984, Volume: 25, Issue:1

    Topics: Aged; Female; Gentamicins; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged;

1984
Serum gentamicin concentrations during intratracheal administration.
    Klinische Wochenschrift, 1984, May-02, Volume: 62, Issue:9

    Topics: Acute Kidney Injury; Adult; Female; Gentamicins; Humans; Intubation, Intratracheal; Kidney Failure,

1984
Gentamicin disposition in children with chronic renal failure.
    Pediatric pharmacology (New York, N.Y.), 1982, Volume: 2, Issue:4

    Topics: Adolescent; Child; Creatinine; Gentamicins; Humans; Kidney Failure, Chronic; Kinetics; Time Factors;

1982
Bobbing oscillopsia from gentamicin toxicity.
    British journal of audiology, 1982, Volume: 16, Issue:2

    Topics: Gentamicins; Humans; Kidney Failure, Chronic; Labyrinth Diseases; Renal Dialysis; Vestibule, Labyrin

1982
Inactivation of amikacin and gentamicin by carbenicillin in patients with end-stage renal failure.
    Antimicrobial agents and chemotherapy, 1982, Volume: 22, Issue:3

    Topics: Amikacin; Carbenicillin; Drug Interactions; Gentamicins; Humans; Kanamycin; Kidney Failure, Chronic;

1982
Prophylactic netilmicin in surgery.
    Current medical research and opinion, 1982, Volume: 8, Issue:4

    Topics: Adult; Aged; Female; Gentamicins; Humans; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Netilm

1982
Dosage of antimicrobial drugs in patients with renal insufficiency.
    Journal of the American Veterinary Medical Association, 1981, Jan-01, Volume: 178, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Dog Diseases; Dogs; Gentamicins; Kidney Failure, Chronic

1981
Gentamicin: use of a programmable calculator to determine dosages from pharmacokinetic data for individual patients.
    Canadian Medical Association journal, 1981, Jun-01, Volume: 124, Issue:11

    Topics: Bacterial Infections; Computers; Gentamicins; Half-Life; Humans; Kidney Failure, Chronic

1981
Pharmacokinetics of gentamicin in patients undergoing continuous ambulatory peritoneal dialysis.
    Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:4

    Topics: Adult; Aged; Ambulatory Care; Gentamicins; Humans; Kidney Failure, Chronic; Kinetics; Middle Aged; P

1981
Pneumonia and bacteremia due to Aeromonas hydrophila.
    Chest, 1981, Volume: 80, Issue:3

    Topics: Adolescent; Adult; Aeromonas; Female; Gentamicins; Humans; Kidney Failure, Chronic; Lung; Lung Absce

1981
Gentamicin-induced ototoxicity in a carefully monitored renal-failure patient.
    American journal of hospital pharmacy, 1981, Volume: 38, Issue:4

    Topics: Adult; Drug Interactions; Ear; Gentamicins; Humans; Kidney Failure, Chronic; Male; Monitoring, Physi

1981
Determining gentamicin dosage in infants and children with renal failure.
    The Journal of pediatrics, 1980, Volume: 96, Issue:2

    Topics: Bacterial Infections; Child; Child, Preschool; Creatinine; Gentamicins; Half-Life; Humans; Infant; I

1980
Prediction of serum gentamicin concentrations in patients undergoing hemodialysis.
    American journal of hospital pharmacy, 1980, Volume: 37, Issue:8

    Topics: Adult; Aged; Bacterial Infections; Drug Administration Schedule; Gentamicins; Humans; Kidney Failure

1980
[Is endogenous creatinine clearance a sound basis for estimation of elimination half life of gentamicin?].
    Deutsche medizinische Wochenschrift (1946), 1980, Nov-21, Volume: 105, Issue:47

    Topics: Adult; Aged; Creatinine; Gentamicins; Glomerular Filtration Rate; Half-Life; Humans; Kidney Failure,

1980
Antioxidants attenuate endotoxin-gentamicin induced acute renal failure in rats.
    Scandinavian journal of urology and nephrology, 1995, Volume: 29, Issue:2

    Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Endotoxins; Free Radical Scavengers; Gentam

1995
Effect of hemodialysis on serum concentration of isepamicin in a patient with endstage renal failure.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:10

    Topics: Aged; Gentamicins; Half-Life; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Renal

1993
Gentamicin ototoxicity in continuous ambulatory peritoneal dialysis.
    The Journal of laryngology and otology, 1993, Volume: 107, Issue:8

    Topics: Adult; Audiometry, Pure-Tone; Drug Administration Schedule; Electronystagmography; Gentamicins; Huma

1993
Antibiotic-resistant endocarditis in a hemodialysis patient.
    Journal of the American Society of Nephrology : JASN, 1996, Volume: 7, Issue:4

    Topics: Ampicillin; Bacteremia; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug T

1996
Acute massive gentamicin intoxication in a patient with end-stage renal disease.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1996, Volume: 28, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Drug Overdose; Gentamicins; Hearing Loss, High-Frequency; Hemoperfusion

1996
Pasteurella multocida peritonitis in patients undergoing peritoneal dialysis.
    Pediatric nephrology (Berlin, Germany), 1997, Volume: 11, Issue:3

    Topics: Anti-Bacterial Agents; Child; Female; Gentamicins; Glomerulosclerosis, Focal Segmental; Humans; Inje

1997
Systemic absorption of gentamicin ear drops.
    The Journal of laryngology and otology, 1997, Volume: 111, Issue:10

    Topics: Absorption; Administration, Topical; Anti-Bacterial Agents; Gentamicins; Humans; Kidney Failure, Chr

1997
Characterization of gentamicin pharmacokinetics in patients hemodialyzed with high-flux polysulfone membranes.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 34, Issue:2

    Topics: Aged; Female; Gentamicins; Half-Life; Humans; Kidney Failure, Chronic; Male; Membranes, Artificial;

1999
Prophylactic antibiotic lock therapy for hemodialysis catheters.
    Nephrology nursing journal : journal of the American Nephrology Nurses' Association, 2000, Volume: 27, Issue:1

    Topics: Anti-Bacterial Agents; Arteriovenous Shunt, Surgical; Cross Infection; Gentamicins; Humans; Infectio

2000
Leclercia adecarboxylata peritonitis in a child receiving chronic peritoneal dialysis.
    Pediatric nephrology (Berlin, Germany), 2000, Volume: 15, Issue:3-4

    Topics: Anti-Bacterial Agents; Cefazolin; Cephalosporins; Child, Preschool; Enterobacteriaceae Infections; E

2000
Clinical course of peritonitis due to Pseudomonas species complicating peritoneal dialysis: a review of 104 cases.
    Kidney international, 2001, Volume: 59, Issue:6

    Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Equipment Contamination; Female; Gentamicins; Hu

2001
Managing the complications of plasma cell myeloma.
    Archives of internal medicine, 1975, Volume: 135, Issue:1

    Topics: Acute Kidney Injury; Bacterial Infections; Blood Urea Nitrogen; Blood Viscosity; Bone Neoplasms; Cep

1975
[The nephrotoxicity of the methicillin-gentamycin combination. Apropos of 5 cases].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1976, Oct-16, Volume: 52, Issue:35

    Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Eosinophilia; Fever; Gentamicins; Hematuria; Hum

1976
[Pharmacokinetics of lividomycin, aminkacin and sisomicin in patients with chronic renal insufficiency].
    Journal d'urologie et de nephrologie, 1977, Volume: 83, Issue:9

    Topics: Amikacin; Gentamicins; Humans; Kanamycin; Kidney Failure, Chronic; Kinetics; Paromomycin; Sisomicin

1977
Endophthalmitis following staphylococcal sepsis in renal failure patients.
    Archives of internal medicine, 1978, Volume: 138, Issue:5

    Topics: Adult; Atropine; Chronic Disease; Dexamethasone; Dicloxacillin; Endophthalmitis; Female; Gentamicins

1978
Vestibular toxicity of gentamicin. Incidence in patients receiving long-term hemodialysis therapy.
    Archives of internal medicine, 1978, Volume: 138, Issue:11

    Topics: Adult; Aged; Body Weight; Female; Gentamicins; Humans; Kidney Failure, Chronic; Labyrinth Diseases;

1978
Elimination of ampicillin and gentamicin by hemofiltration.
    Klinische Wochenschrift, 1979, Feb-15, Volume: 57, Issue:4

    Topics: Ampicillin; Blood; Filtration; Gentamicins; Half-Life; Humans; Kidney Failure, Chronic; Renal Dialys

1979
[Urinary tract infections. Problems in treating dialysis patients with toxic drugs].
    Lakartidningen, 1979, May-30, Volume: 76, Issue:22

    Topics: Anti-Bacterial Agents; Gentamicins; Humans; Kidney Failure, Chronic; Renal Dialysis; Urinary Tract I

1979
Changes in the apparent half life of gentamicin and tobramycin without detectable changes in creatinine clearance.
    British journal of clinical pharmacology, 1979, Volume: 7, Issue:6

    Topics: Adult; Aged; Anti-Bacterial Agents; Creatinine; Female; Gentamicins; Half-Life; Humans; Kidney Failu

1979
[Sisomicin dosage in renal failure].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1979, Nov-15, Volume: 32, Issue:22

    Topics: Acute Kidney Injury; Gentamicins; Humans; Kidney Failure, Chronic; Kinetics; Sisomicin

1979
Drug elimination by hemofiltration.
    Journal of dialysis, 1977, Volume: 1, Issue:7

    Topics: Ampicillin; Anti-Bacterial Agents; Clofibrate; Doxycycline; Filtration; Gentamicins; Humans; Kidney

1977
Pharmacokinetics of netilmicin in the presence of normal or impaired renal function.
    Antimicrobial agents and chemotherapy, 1978, Volume: 14, Issue:1

    Topics: Adult; Aged; Creatinine; Gentamicins; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Middle A

1978
Nephrotoxic antibiotics in patients with renal failures: guidelines for debilitated patients.
    Critical care medicine, 1979, Volume: 7, Issue:1

    Topics: Aminoglycosides; Body Weight; Creatine; Emaciation; Gentamicins; Humans; Kidney; Kidney Failure, Chr

1979
[Serratia marcescens infections in chronic hemodialysis patients].
    Zeitschrift fur Urologie und Nephrologie, 1975, Volume: 68, Issue:9

    Topics: Cross Infection; Drug Resistance, Microbial; Enterobacteriaceae Infections; Gentamicins; Germany, Ea

1975
Gentamicin pharmacokinetics during hemodialysis in patients suffering from chronic renal failure.
    International journal of clinical pharmacology and biopharmacy, 1977, Volume: 15, Issue:3

    Topics: Adult; Female; Gentamicins; Humans; Injections, Intravenous; Kidney Failure, Chronic; Kinetics; Male

1977
[Nephrotoxicity of gentamicin. Conditions for the use of this antibiotic in the elderly and in the patient with renal insufficiency].
    La Nouvelle presse medicale, 1977, Mar-19, Volume: 6, Issue:11

    Topics: Acute Kidney Injury; Adult; Age Factors; Aged; Anti-Bacterial Agents; Drug Therapy, Combination; Fem

1977
Inactivation of gentamicin by penicillins in patients with renal failure.
    Antimicrobial agents and chemotherapy, 1976, Volume: 9, Issue:6

    Topics: Carbenicillin; Gentamicins; Humans; Kidney Failure, Chronic; Kinetics; Penicillins; Ticarcillin; Tim

1976
Carbenicillin inactivation of aminoglycosides in patients with severe renal failure.
    Transactions - American Society for Artificial Internal Organs, 1976, Volume: 22

    Topics: Aged; Anti-Bacterial Agents; Carbenicillin; Drug Interactions; Drug Therapy, Combination; Female; Ge

1976
Amikacin in obstetric, gynecologic, and neonatal infections: laboratory and clinical studies.
    The Journal of infectious diseases, 1976, Volume: 134 SUPPL

    Topics: Amikacin; Bacterial Infections; Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae I

1976
[Determination of the optimal gentamicin dosage in limited kidney function].
    Die Medizinische Welt, 1976, Nov-19, Volume: 27, Issue:47

    Topics: Biological Availability; Gentamicins; Humans; Kidney Failure, Chronic; Microbial Sensitivity Tests

1976
Practical pharmacokinetic techniques for drug consultation and evaluation. IV: Gentamicin blood level versus time profiles of various dosage regimens recommended for renal impairment.
    American journal of hospital pharmacy, 1975, Volume: 32, Issue:3

    Topics: Adult; Aged; Computers; Creatinine; Female; Gentamicins; Half-Life; Humans; Kidney Failure, Chronic;

1975
[Antibiotic therapy and renal insufficiency. Pharmacokinetics of pivampicillin, cephaloridin and streptomycin in chronic uremic patients undergoing conservative or hemodialytic treatment].
    Minerva medica, 1975, Oct-13, Volume: 66, Issue:68

    Topics: Ampicillin; Binding Sites; Carbenicillin; Cephalexin; Cephaloridine; Chronic Disease; Gentamicins; H

1975
Prophylactic antibiotics in the insertion of Tenckhoff catheters.
    Scandinavian journal of urology and nephrology, 1992, Volume: 26, Issue:2

    Topics: Adult; Aged; Catheters, Indwelling; Cefazolin; Female; Gentamicins; Humans; Kidney Failure, Chronic;

1992
Beneficial effects of the urinary trypsin inhibitor urinastatin on renal insults induced by gentamicin and mercuric chloride (HgCl2) poisoning.
    Nephron, 1991, Volume: 58, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Epithelium; Gentamicins; Glomerular Filtration Rate; Glyc

1991
Isepamicin disposition in subjects with various degrees of renal function.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:11

    Topics: Adult; Aged; Female; Gentamicins; Humans; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Ma

1991
Vestibular toxicity due to gentamicin in peritoneal dialysis patients.
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 1991, Volume: 11, Issue:2

    Topics: Adult; Aged; Bacterial Infections; Catheters, Indwelling; Female; Gentamicins; Humans; Infusions, Pa

1991
Gentamicin and vancomycin removal by continuous venovenous hemofiltration.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:2

    Topics: Bayes Theorem; Drug Administration Schedule; Endocarditis, Bacterial; Gentamicins; Hemofiltration; H

1991
[Peritonitis in continuous ambulatory peritoneal dialysis. Microbiological and clinical evaluation].
    Medicina, 1990, Volume: 50, Issue:2

    Topics: Adult; Aged; Cephalothin; Drug Resistance, Microbial; Female; Gentamicins; Humans; Kidney Failure, C

1990
Therapeutic drug monitoring in patients with chronic renal failure: evaluation of the Abbott TDx drug assay system.
    American journal of nephrology, 1986, Volume: 6, Issue:2

    Topics: Carbamazepine; Cross Reactions; Digoxin; Gentamicins; Humans; Immunoassay; Kidney Failure, Chronic;

1986
Chronic tubulointerstitial nephritis and renal insufficiency associated with long-term "subtherapeutic" gentamicin.
    The Journal of laboratory and clinical medicine, 1988, Volume: 112, Issue:6

    Topics: Animals; Autoradiography; Gentamicins; Glomerular Filtration Rate; Inulin; Kidney Failure, Chronic;

1988
Renal cortical uptake kinetics of gentamicin in rats with impaired renal function.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1986, Volume: 8, Issue:5

    Topics: Animals; Creatinine; Female; Gentamicins; Glomerular Filtration Rate; Kidney Cortex; Kidney Failure,

1986
Time course of gentamicin serum concentration rebound following hemodialysis.
    Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:1 Pt 1

    Topics: Aged; Creatinine; Gentamicins; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Renal D

1987
Early monitoring of human renal transplantations by N-acetyl-beta-D-glucosaminidase isoenzyme activities in urines.
    Clinica chimica acta; international journal of clinical chemistry, 1985, Jul-15, Volume: 149, Issue:2-3

    Topics: Acetylglucosaminidase; Gentamicins; Graft Rejection; Hexosaminidases; Humans; Isoenzymes; Kidney Fai

1985
[Intracellular calcium and renal function].
    Medicina clinica, 1985, Jun-22, Volume: 85, Issue:4

    Topics: Acute Kidney Injury; Animals; Biological Transport, Active; Calcium; Calcium Channel Blockers; Calmo

1985
Carbenicillin-induced coagulopathy.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Mar-09, Volume: 48, Issue:11

    Topics: Adult; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Tests; Carbenicillin; Femal

1974
[Deafness and gentallin].
    JFORL. Journal francais d'oto-rhino-laryngologie; audiophonologie et chirurgie maxillo-faciale, 1972, Volume: 21, Issue:4

    Topics: Adult; Audiometry; Cochlea; Deafness; Ear, Inner; Female; Gentamicins; Humans; Kidney Failure, Chron

1972
[Gentamicin and auricular toxicity].
    Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 1969, Volume: 86, Issue:9

    Topics: Adult; Animals; Audiometry; Deafness; Ear Diseases; Ear, Inner; Female; Gentamicins; Guinea Pigs; Hi

1969
[Antibiotics in renal insufficiency (author's transl)].
    Praktische Anasthesie, Wiederbelebung und Intensivtherapie, 1974, Volume: 9, Issue:1

    Topics: Acute Kidney Injury; Ampicillin; Anti-Bacterial Agents; Carbenicillin; Cephaloridine; Cephalothin; C

1974
Gentamicin pharmacokinetics during hemodialysis.
    Kidney international, 1974, Volume: 6, Issue:1

    Topics: Adult; Blood Proteins; Creatinine; Female; Gentamicins; Glomerular Filtration Rate; Humans; In Vitro

1974
Infections in renal failure.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Mar-10, Volume: 47, Issue:10

    Topics: Acute Kidney Injury; Ampicillin; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cephalothin;

1973
[Antibiotic therapy].
    Medizinische Klinik, 1973, Dec-14, Volume: 68, Issue:50

    Topics: Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Chloramphenicol; Colistin; Drug Therapy

1973
[Nephrology in 1972].
    La Revue du praticien, 1972, May-21, Volume: 22, Issue:15

    Topics: Bone Resorption; Calcium; Dextrans; Female; Fluorescent Antibody Technique; Gentamicins; Glomerulone

1972
Neomycin toxicity from porcine skin xenografts.
    Annals of surgery, 1974, Volume: 179, Issue:2

    Topics: Aged; Animals; Burns; Chromatography, Paper; Deafness; Ear; Female; Gentamicins; Humans; Kidney; Kid

1974
Gentamicin therapy in renal failure: a nomogram for dosage.
    Annals of internal medicine, 1972, Volume: 76, Issue:5

    Topics: Adult; Aged; Bacillus subtilis; Bacterial Infections; Creatinine; Gentamicins; Half-Life; Humans; In

1972
[Urologic surgery in urinary infections and renal failure].
    La Nouvelle presse medicale, 1973, Jan-06, Volume: 2, Issue:1

    Topics: Cephalothin; Colistin; Enterococcus faecalis; Escherichia coli Infections; Gentamicins; Humans; Kana

1973
[Elimination kinetics of gentamicin in kidney insufficiency].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1973, Apr-10, Volume: 62, Issue:15

    Topics: Adult; Aged; Creatinine; Female; Gentamicins; Humans; Kidney Failure, Chronic; Kinetics; Male; Metab

1973
[Side-effects of gentamicin. Report of a case treated for an unusually long period].
    Minerva pediatrica, 1973, Apr-17, Volume: 25, Issue:12

    Topics: Female; Gentamicins; Humans; Infant; Kidney Diseases; Kidney Failure, Chronic; Time Factors; Urinary

1973
[Gentamicin and peritoneal dialysis].
    Acta clinica Belgica, 1973, Volume: 28, Issue:2

    Topics: Acute Kidney Injury; Gentamicins; Humans; Kidney Failure, Chronic; Peritoneal Dialysis

1973
[Gentamicin and hemodialysis].
    Acta clinica Belgica, 1973, Volume: 28, Issue:2

    Topics: Acute Kidney Injury; Gentamicins; Humans; Kidney Failure, Chronic; Renal Dialysis

1973
[Pharmacokinetics of gentamicin in adults and children of various ages].
    Die Medizinische Welt, 1973, Apr-20, Volume: 24, Issue:16

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Gentamicins; Humans; Infant; Kidney Failur

1973
[The difficulties of drug management in renal insufficiency (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1974, Jun-18, Volume: 63, Issue:24

    Topics: Acute Kidney Injury; Gentamicins; Humans; Kidney Failure, Chronic; Tetracycline

1974
The unpredictability of serum concentrations of gentamicin: pharmacokinetics of gentamicin in patients with normal and abnormal renal function.
    The Journal of infectious diseases, 1974, Volume: 130, Issue:2

    Topics: Creatinine; Gentamicins; Humans; Kidney Failure, Chronic

1974
Peritoneal clearance and removal of gentamicin.
    The Journal of infectious diseases, 1971, Volume: 124 Suppl

    Topics: Acute Kidney Injury; Aged; Enterobacteriaceae Infections; Female; Gentamicins; Humans; Kidney Failur

1971
The use of gentamicin in peritoneal dialysis. II. Microbiologic and clinical results.
    The Journal of infectious diseases, 1971, Volume: 124 Suppl

    Topics: Acute Kidney Injury; Alcaligenes; Candidiasis; Carbenicillin; Cephalothin; Drug Synergism; Escherich

1971
[Pharmacokinetics of gentamycin sulfate in the healthy and in patients with terminal renal failure].
    Deutsche medizinische Wochenschrift (1946), 1971, Apr-23, Volume: 96, Issue:17

    Topics: Bacillus subtilis; Feces; Gentamicins; Half-Life; Humans; Kidney; Kidney Failure, Chronic; Male; Per

1971
Rapid microassay of gentamicin, kanamycin, neomycin, streptomycin, and vancomycin in serum or plasma.
    The Journal of laboratory and clinical medicine, 1971, Volume: 78, Issue:3

    Topics: Bacillus cereus; Bacterial Infections; Culture Media; Gentamicins; Humans; Kanamycin; Kidney Failure

1971
Relation between dose and levels of gentamicin in blood.
    The Journal of infectious diseases, 1971, Volume: 124 Suppl

    Topics: Acute Kidney Injury; Agar; Biological Assay; Clinical Laboratory Techniques; Creatinine; Gentamicins

1971
[Recent developments in antibiotics].
    Schweizerische medizinische Wochenschrift, 1972, Feb-26, Volume: 102, Issue:8

    Topics: Bacteria; Carbenicillin; Culture Techniques; Drug Antagonism; Drug Synergism; Gentamicins; Humans; K

1972
Correlation of serum creatinine concentration and gentamicin half-life.
    JAMA, 1972, Feb-21, Volume: 219, Issue:8

    Topics: Creatinine; Gentamicins; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Staphylococcus

1972
The use of gentamicin in peritoneal dialysis. I. Pharmacologic results.
    The Journal of infectious diseases, 1971, Volume: 124 Suppl

    Topics: Acute Kidney Injury; Drug Resistance, Microbial; Gentamicins; Half-Life; Humans; Injections, Intramu

1971
[Review of observed gentamicin ototoxicity cases in Germany].
    HNO, 1971, Volume: 19, Issue:11

    Topics: Adolescent; Adult; Aged; Diabetes Complications; Drug Synergism; Ethacrynic Acid; Gentamicins; Germa

1971
[Antimicrobial chemotherapy in liver and kidney lesions].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1971, Volume: 77

    Topics: Aminosalicylic Acids; Anti-Infective Agents; Creatinine; Gentamicins; Humans; Kidney Failure, Chroni

1971
A case of gentamicin accentuated hearing loss.
    The Journal of laryngology and otology, 1968, Volume: 82, Issue:9

    Topics: Adult; Audiometry; Deafness; Gentamicins; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Str

1968
Renal tissue levels of gentamicin and a dose schedule in renal impairment.
    Therapeutische Umschau. Revue therapeutique, 1969

    Topics: Animals; Dogs; Gentamicins; Humans; Kidney; Kidney Failure, Chronic

1969