Page last updated: 2024-10-27

gentamicin and Chronic Kidney Diseases

gentamicin has been researched along with Chronic Kidney Diseases in 12 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
" Likewise, de-indexation of eGFR to body surface area (BSA) has been recommended by regulatory guidance for drug dosing in renal impairment."1.91Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles. ( Abdelnabi, M; Pai, MP; Sitaruno, S, 2023)
"Symmetric dimethylarginine (SDMA) is an excretory renal function biomarker shown to correlate well with glomerular filtration rate in dogs, cats, humans, and rats."1.72Evaluation of Renal Biomarkers, Including Symmetric Dimethylarginine, following Gentamicin-Induced Proximal Tubular Injury in the Rat. ( Coyne, MJ; Cross, J; Drake, C; Hamlin, DM; Leissinger, MK; Mack, R; McCrann, DJ; Murphy, RE; Schultze, AE; Strong-Townsend, M; Yerramilli, M, 2022)
"Aminoglycoside clearance depends on kidney function, but the Australian Therapeutic Guidelines for antibiotics (version 14, 2010) recommend initial dosing based on weight without consideration of kidney function."1.42Assessment of aminoglycoside dosing and estimated glomerular filtration rate in determining gentamicin and tobramycin area under the curve and clearance. ( Larmour, I; Lim, AK; Mathanasenarajah, G, 2015)
"Moxifloxacin was added as an anti-chlamydial agent, but neurologic symptoms returned."1.42[Infective endocarditis caused by Chlamydia pneumoniae after liver transplantation. Case report]. ( Balla, J; Fehérvári, I; Kertész, A; Nemes, B; P Szabó, R; Szerafin, T; Zsom, L, 2015)
"Gentamicin clearance was calculated from plasma concentrations using a one-compartment model."1.39The performances of the Cockcroft-Gault, modification of diet in renal disease study and chronic kidney disease epidemiology collaboration equations in predicting gentamicin clearance. ( Begg, EJ; Chin, PK; Florkowski, CM, 2013)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (58.33)24.3611
2020's5 (41.67)2.80

Authors

AuthorsStudies
Hamlin, DM1
Schultze, AE1
Coyne, MJ1
McCrann, DJ1
Mack, R1
Drake, C1
Murphy, RE1
Cross, J1
Strong-Townsend, M1
Yerramilli, M1
Leissinger, MK1
Alharbi, KS1
Ali, T1
Singh, Y1
Ali Al-Ghamdi, AS1
Kazmi, I1
Al-Abbasi, FA1
Alzarea, SI1
Afzal, O1
Alfawaz Altamimi, AS1
Singh, SK1
Chellappan, DK1
Dua, K1
Gupta, G1
Pai, MP3
Sitaruno, S3
Abdelnabi, M3
Good, PI1
Li, L1
Hurst, HA1
Serrano Herrera, I1
Xu, K1
Rao, M1
Bateman, DA1
Al-Awqati, Q1
D'Agati, VD1
Costantini, F1
Lin, F1
Dagneaux, L1
Limberg, AK1
Osmon, DR1
Leung, N1
Berry, DJ1
Abdel, MP1
Goh, TL1
Wei, J1
Semple, D1
Collins, J1
Ramírez Hidalgo, M1
Jover-Sáenz, A1
García-González, M1
Barcenilla-Gaite, F1
Chin, PK2
Florkowski, CM2
Begg, EJ2
Bosomworth, MP1
Sandoe, JA1
Chew-Harris, JS1
Lim, AK1
Mathanasenarajah, G1
Larmour, I1
P Szabó, R1
Kertész, A1
Szerafin, T1
Fehérvári, I1
Zsom, L1
Balla, J1
Nemes, B1

Reviews

1 review available for gentamicin and Chronic Kidney Diseases

ArticleYear
Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction.
    Chemico-biological interactions, 2022, Aug-25, Volume: 363

    Topics: Acute Kidney Injury; beta Catenin; Calcium; Gentamicins; Humans; Mitochondria; Pyrvinium Compounds;

2022

Other Studies

11 other studies available for gentamicin and Chronic Kidney Diseases

ArticleYear
Evaluation of Renal Biomarkers, Including Symmetric Dimethylarginine, following Gentamicin-Induced Proximal Tubular Injury in the Rat.
    Kidney360, 2022, 02-24, Volume: 3, Issue:2

    Topics: Animals; Arginine; Biomarkers; Dog Diseases; Dogs; Gentamicins; Kidney; Rats; Renal Insufficiency, C

2022
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
    Pharmacotherapy, 2023, Volume: 43, Issue:1

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula

2023
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
    Pharmacotherapy, 2023, Volume: 43, Issue:1

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula

2023
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
    Pharmacotherapy, 2023, Volume: 43, Issue:1

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula

2023
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
    Pharmacotherapy, 2023, Volume: 43, Issue:1

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula

2023
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
    Pharmacotherapy, 2023, Volume: 43, Issue:1

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula

2023
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
    Pharmacotherapy, 2023, Volume: 43, Issue:1

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula

2023
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
    Pharmacotherapy, 2023, Volume: 43, Issue:1

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula

2023
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
    Pharmacotherapy, 2023, Volume: 43, Issue:1

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula

2023
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
    Pharmacotherapy, 2023, Volume: 43, Issue:1

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula

2023
Low nephron endowment increases susceptibility to renal stress and chronic kidney disease.
    JCI insight, 2023, 02-08, Volume: 8, Issue:3

    Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Humans; Hypertrophy; Infant, Premature; Kidney; M

2023
Acute Kidney Injury When Treating Periprosthetic Joint Infections After Total Knee Arthroplasties with Antibiotic-Loaded Spacers: Incidence, Risks, and Outcomes.
    The Journal of bone and joint surgery. American volume, 2021, 05-05, Volume: 103, Issue:9

    Topics: Acute Kidney Injury; Administration, Oral; Adult; Aged; Aged, 80 and over; Amphotericin B; Anti-Bact

2021
The incidence and costs of bacteremia due to lack of gentamicin lock solutions for dialysis catheters.
    Nephrology (Carlton, Vic.), 2017, Volume: 22, Issue:6

    Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Catheters, Indwelling;

2017
Dalbavancin treatment of prosthetic knee infection due to oxacillin-resistant Staphylococcus epidermidis.
    Enfermedades infecciosas y microbiologia clinica (English ed.), 2018, Volume: 36, Issue:2

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Device Removal; Drug Resistance, Multiple, B

2018
The performances of the Cockcroft-Gault, modification of diet in renal disease study and chronic kidney disease epidemiology collaboration equations in predicting gentamicin clearance.
    Annals of clinical biochemistry, 2013, Volume: 50, Issue:Pt 6

    Topics: Adolescent; Adult; Aged; Cooperative Behavior; Creatinine; Diet; Female; Gentamicins; Humans; Male;

2013
Drug dosing and estimates of kidney function.
    Annals of clinical biochemistry, 2013, Volume: 50, Issue:Pt 6

    Topics: Cooperative Behavior; Diet; Female; Gentamicins; Humans; Male; Models, Biological; Renal Insufficien

2013
The performance of contemporary cystatin C-based GFR equations in predicting gentamicin clearance.
    British journal of clinical pharmacology, 2015, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Body Mass Index; Creatinine; Cyst

2015
Assessment of aminoglycoside dosing and estimated glomerular filtration rate in determining gentamicin and tobramycin area under the curve and clearance.
    Internal medicine journal, 2015, Volume: 45, Issue:3

    Topics: Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Area Under Curve; Dose-Response Rel

2015
[Infective endocarditis caused by Chlamydia pneumoniae after liver transplantation. Case report].
    Orvosi hetilap, 2015, May-31, Volume: 156, Issue:22

    Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Aortic Valve; Aphasia; Brain; Calcineurin; Ceftriaxone

2015