gentamicin has been researched along with Cholangitis in 20 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Cholangitis: Inflammation of the biliary ductal system (BILE DUCTS); intrahepatic, extrahepatic, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "With adequate drainage of the obstructed biliary tract by proper stenting, adding gentamicin to contrast media had no significant effect on incidence of post-ERCP cholangitis." | 9.17 | The effect of adding gentamicin to contrast media for prevention of cholangitis after biliary stenting for non-calculous biliary obstruction, a randomized controlled trial. ( Afroogh, R; Chaharmahali, M; Khatibian, M; Norouzi, A; Sotoudehmanesh, R, 2013) |
| "Forty-six patients with cholangitis were randomized to receive therapy with mezlocillin sodium (24 patients) or a combination of ampicillin sodium--gentamicin sulfate (22 patients)." | 9.06 | Prospective randomized comparison of mezlocillin therapy alone with combined ampicillin and gentamicin therapy for patients with cholangitis. ( Gerecht, WB; Henry, NK; Hoffman, WW; LaRusso, NF; Muller, SM; Rosenblatt, JE; Wilson, WR, 1989) |
| "With adequate drainage of the obstructed biliary tract by proper stenting, adding gentamicin to contrast media had no significant effect on incidence of post-ERCP cholangitis." | 5.17 | The effect of adding gentamicin to contrast media for prevention of cholangitis after biliary stenting for non-calculous biliary obstruction, a randomized controlled trial. ( Afroogh, R; Chaharmahali, M; Khatibian, M; Norouzi, A; Sotoudehmanesh, R, 2013) |
| "One hundred and eighty-nine patients with acute cholecystitis or cholangitis requiring antibacterial therapy and surgery were randomly allocated in a prospective open study to receive either iv or oral pefloxacin (800 mg per day) or a combination of iv or oral ampicillin (4 g per day) and gentamicin (240 mg per day im)." | 5.06 | Prospective randomized comparison of pefloxacin and ampicillin plus gentamicin in the treatment of bacteriologically proven biliary tract infections. ( Chacon, JP; Criscuolo, PD; Ferraro, JR; Kobata, CM; Reis, C; Saad, SS, 1990) |
| " Similarly, resistance to ampicillin and gentamicin, the empirically used antibiotics for patients with fever of unknown origin, was found in E." | 3.69 | Stool cultures obtained before liver transplantation are useful for choice of perioperative antibiotic prophylaxis. ( Andersson, J; Barkholt, LM; Bergquist, A; Broomé, U; Duraj, F; Ericzon, BG; Herlenius, G; Nord, CE; Palmgren, AC, 1997) |
| "Gentamicin (GM) was intramuscularly administered to 24 patients with various infections (including 1 for prophylaxis of a postoperative infection) in the dose of 40 mg X 2/day for 4-26 days." | 1.26 | [Clinical use of gentamicin in the field of surgery (author's transl)]. ( Ishii, T; Kishi, D; Nakai, S; Sugihara, H; Yokoyama, T, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (65.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Q | 1 |
| Wu, Z | 1 |
| Liu, F | 1 |
| Wang, J | 1 |
| Ma, W | 1 |
| Hu, H | 1 |
| Li, F | 1 |
| Pan, Q | 1 |
| van Bunderen, CC | 1 |
| Bomers, MK | 1 |
| Wesdorp, E | 1 |
| Peerbooms, P | 1 |
| Veenstra, J | 1 |
| Norouzi, A | 1 |
| Khatibian, M | 1 |
| Afroogh, R | 1 |
| Chaharmahali, M | 1 |
| Sotoudehmanesh, R | 1 |
| Bukharin, OV | 1 |
| Gritsenko, VA | 1 |
| Tret'iakov, AA | 1 |
| Chernikov, DA | 1 |
| Pardelli, G | 1 |
| Philben, V | 1 |
| Krantz, BE | 1 |
| Polk, HC | 1 |
| Fink, MP | 1 |
| Laverdiere, M | 1 |
| Wilson, SE | 1 |
| Garber, GE | 1 |
| Barie, PS | 1 |
| Hebert, JC | 1 |
| Cheadle, WG | 1 |
| Barkholt, LM | 1 |
| Andersson, J | 1 |
| Ericzon, BG | 1 |
| Palmgren, AC | 1 |
| Broomé, U | 1 |
| Duraj, F | 1 |
| Bergquist, A | 1 |
| Herlenius, G | 1 |
| Nord, CE | 1 |
| Keighley, MR | 1 |
| Drysdale, RB | 1 |
| Quoraishi, AH | 1 |
| Burdon, DW | 1 |
| Alexander-Williams, J | 1 |
| Howlett, SA | 1 |
| Shulman, ST | 1 |
| Ayoub, EM | 1 |
| Alexander, RA | 1 |
| Donnelly, WH | 1 |
| Cerda, JJ | 1 |
| Ishii, T | 1 |
| Yokoyama, T | 1 |
| Kishi, D | 1 |
| Nakai, S | 1 |
| Sugihara, H | 1 |
| Chacon, JP | 1 |
| Criscuolo, PD | 1 |
| Kobata, CM | 1 |
| Ferraro, JR | 1 |
| Saad, SS | 1 |
| Reis, C | 1 |
| Gerecht, WB | 1 |
| Henry, NK | 1 |
| Hoffman, WW | 1 |
| Muller, SM | 1 |
| LaRusso, NF | 1 |
| Rosenblatt, JE | 1 |
| Wilson, WR | 1 |
| Twidale, N | 1 |
| MacKinnon, M | 1 |
| Watts, J | 1 |
| Desai, TK | 1 |
| Tsang, TK | 1 |
| Stillman, AE | 1 |
| Earnest, DL | 1 |
| Woolfenden, JM | 1 |
| Astrozhnikov, IuV | 1 |
| Bogomolova, NS | 1 |
| Vinogradova, LN | 1 |
| Gorel'chenkova, VG | 1 |
| Wilde, H | 1 |
| Ventura, E | 1 |
| Zeneroli, ML | 1 |
| Smithivas, T | 1 |
| Hyams, PJ | 1 |
| Rahal, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparing Addition of Gentamicin vs. Placebo in Preventing Post ERCP Cholangitis in Non-calculus Stenting[NCT01148693] | 114 participants (Actual) | Interventional | 2009-12-31 | Completed | |||
| Antibiotic Treatment Versus no Antibiotics in the Postoperative Acute Cholecystitis Low and Moderately Severe[NCT01015417] | Phase 3 | 414 participants (Actual) | Interventional | 2010-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
After Endoscopic Retrograde CholangioPancreatography (ERCP) in 3 following days we check all participants for syptoms of cholangitis (fever, chills, right upper qudrant (RUQ) pain, leukocytosis) and ruling out other diagnoses than cholangitis (NCT01148693)
Timeframe: 72 hours
| Intervention | participants (Number) |
|---|---|
| Gentamicin | 5 |
| Placebo | 5 |
1 review available for gentamicin and Cholangitis
| Article | Year |
|---|---|
Clostridium perfringens septicaemia with massive intravascular haemolysis: a case report and review of the literature.
Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Cholangitis; Clostridium Infections; Clostridium perfringe | 2010 |
5 trials available for gentamicin and Cholangitis
| Article | Year |
|---|---|
The effect of adding gentamicin to contrast media for prevention of cholangitis after biliary stenting for non-calculous biliary obstruction, a randomized controlled trial.
Topics: Aged; Anti-Bacterial Agents; Bile Ducts, Intrahepatic; Cholangiopancreatography, Endoscopic Retrogra | 2013 |
Prospective randomized study of piperacillin/tazobactam therapy of surgically treated intra-abdominal infection. The Piperacillin/Tazobactam Intra-Abdominal Infection Study Group.
Topics: Abdomen; Abscess; Adolescent; Adult; Aged; Aged, 80 and over; Appendicitis; Bacterial Infections; be | 1993 |
Antibiotic treatment of biliary sepsis.
Topics: Ampicillin; Anti-Bacterial Agents; Bile; Biliary Tract Diseases; Cholangitis; Cholecystectomy; Clini | 1975 |
Prospective randomized comparison of pefloxacin and ampicillin plus gentamicin in the treatment of bacteriologically proven biliary tract infections.
Topics: Adolescent; Adult; Ampicillin; Cholangitis; Cholecystitis; Drug Therapy, Combination; Enterobacteria | 1990 |
Prospective randomized comparison of mezlocillin therapy alone with combined ampicillin and gentamicin therapy for patients with cholangitis.
Topics: Adult; Aged; Aged, 80 and over; Ampicillin; Cholangitis; Creatinine; Drug Resistance, Microbial; Dru | 1989 |
14 other studies available for gentamicin and Cholangitis
| Article | Year |
|---|---|
Effective Treatment of Chronic Proliferative Cholangitis by Local Gentamicin Infusion in Rabbits.
Topics: Animals; Anti-Bacterial Agents; Asia, Eastern; Bile Ducts; Bile Ducts, Intrahepatic; Cholangitis; Di | 2018 |
[Taxonomic spectrum and antibiotic resistance of Enterobacteriaceae isolated from bile of patients with cholangitis].
Topics: Adult; Aged; Aged, 80 and over; Amikacin; Amoxicillin; Anti-Bacterial Agents; Bile; Cefazolin; Cefot | 2006 |
[1st clinical experiments with a new antibiotic, gentamicin].
Topics: Adult; Aged; Biliary Tract Diseases; Cholangitis; Cholecystitis; Female; Gentamicins; Humans; Inject | 1967 |
Nontraumatic perforation of the common bile duct.
Topics: Adult; Aged; Bile Duct Diseases; Cholangitis; Cystic Duct; Gentamicins; Humans; Rupture, Spontaneous | 1981 |
Stool cultures obtained before liver transplantation are useful for choice of perioperative antibiotic prophylaxis.
Topics: Adult; Ampicillin; Ampicillin Resistance; Antibiotic Prophylaxis; Bacterial Infections; Cholangitis; | 1997 |
Cholangitis complicating congenital hepatic fibrosis.
Topics: Biopsy, Needle; Cholangitis; Female; Gentamicins; Humans; Infant; Liver Cirrhosis | 1975 |
[Clinical use of gentamicin in the field of surgery (author's transl)].
Topics: Abscess; Adolescent; Adult; Aged; Cellulitis; Child; Child, Preschool; Cholangitis; Endocarditis, Ba | 1976 |
Recurrent cholangitis caused by hepatocellular carcinoma.
Topics: Ampicillin; Carcinoma, Hepatocellular; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis; | 1985 |
Aminoglycoside nephrotoxicity in obstructive jaundice.
Topics: Amikacin; Anti-Bacterial Agents; Cholangitis; Cholestasis; Female; Gentamicins; Humans; Kidney; Kidn | 1988 |
Hepatobiliary scintigraphy for cholestasis in congenital hepatic fibrosis. Diagnosis and treatment.
Topics: Bile Ducts, Intrahepatic; Child; Cholangitis; Cholestasis; Dehydrocholic Acid; Gentamicins; Humans; | 1985 |
[Use of getamicin in reconstructive surgery].
Topics: Abscess; Adult; Bacterial Infections; Child; Cholangitis; Empyema; Escherichia coli; Gentamicins; Hu | 1974 |
Biliary calculus associated with opisthorchiasis.
Topics: Adult; Ampicillin; Bile; Biliary Tract; Cholangitis; Cholelithiasis; Dehydration; Escherichia coli; | 1973 |
[Gentamicin and hepatobiliary infections].
Topics: Aged; Bacterial Infections; Cholangitis; Female; Gallbladder Diseases; Gentamicins; Humans; Liver Di | 1973 |
Gentamicin and ampicillin in human bile.
Topics: Alkaline Phosphatase; Ampicillin; Bile; Bile Ducts; Cholangitis; Creatinine; Drug Synergism; Gentami | 1971 |