gentamicin has been researched along with Catheter-Associated Infections in 38 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1% gentamicin cream is not an effective alternative to reduce significant bacteriuria and prevent urinary infection in patients who undergo clean intermittent catheterization." | 5.16 | [Clean vesical intermittent catheterization: lubrication of vesical catheter through lidocaine or gentamicine?]. ( Liotta, RF; Tarantino, ML, 2012) |
| " Gentamicin has comparable efficacy to mupirocin for peritonitis and gram-positive exit-site infection." | 4.98 | Comparison of topical mupirocin and gentamicin in the prevention of peritoneal dialysis-related infections: A systematic review and meta-analysis. ( Cheng, SP; Hsu, YC; Liu, CL; Tsai, CC; Wu, CJ; Yang, PS, 2018) |
| "The aim of this study was to describe the safety profile and pharmacokinetic/pharmacodynamic parameters in end-stage renal disease patients who received gentamicin as empirical treatment in catheter-related bacteremia when they showed infection signs, regardless of the timing of the next HD." | 3.91 | Gentamicin as Empirical Treatment in Hemodialysis Patients: Safety, Pharmacokinetics, and Pharmacodynamics. ( Camacho-Martínez, P; Gil-Navarro, MV; Gil-Sacaluga, L; Guisado-Gil, AB; Herrera-Hidalgo, L; Lepe-Jiménez, JA; Molina, J; Santos-Rubio, MD, 2019) |
| " But the safety of long-term use of antimicrobial lock still needs to be defined." | 2.74 | Successful prevention of cuffed hemodialysis catheter-related infection using an antibiotic lock technique by strictly catheter-restricted antibiotic lock solution method. ( Chen, J; Lv, R; Tan, H; Yuan, J; Zhang, P, 2009) |
| "Gentamicine was more effective than vancomycine." | 1.51 | In vitro comparison of efficacy of catheter locks in the treatment of catheter related blood stream infection. ( Blaha, V; Lasticova, M; Ryskova, L; Safranek, R; Visek, J, 2019) |
| " Gentamicin, amikacin or vancomycin was combined with disodium EDTA or l-arginine for 24 h to reproduce the antibiotic lock therapy (ALT) approach." | 1.42 | In vitro activity of gentamicin, vancomycin or amikacin combined with EDTA or l-arginine as lock therapy against a wide spectrum of biofilm-forming clinical strains isolated from catheter-related infections. ( Beloin, C; Ghigo, JM; Lebeaux, D; Leflon-Guibout, V, 2015) |
| "Gentamicin was quantified with FTIR only (1045-1169cm(-1) and 2715-2850cm(-1)) due to interferences in UV domain of parabens, preservatives present in the commercial brand used to prepare locks." | 1.40 | Development of a Fourier transform infrared spectroscopy coupled to UV-Visible analysis technique for aminosides and glycopeptides quantitation in antibiotic locks. ( Ben Reguiga, M; Sayet, G; Sinegre, M, 2014) |
| "Gentamicin-EDTA lock was able to eliminate biofilms with a single instillation, thus reducing length of treatment." | 1.38 | Full and broad-spectrum in vivo eradication of catheter-associated biofilms using gentamicin-EDTA antibiotic lock therapy. ( Beloin, C; Chauhan, A; Ghigo, JM; Lebeaux, D, 2012) |
| "When gentamicin was combined with sodium citrate and stored at 37 degrees C in dialysis catheters, the solution showed no decrease in either the gentamicin or the sodium citrate concentrations over the 96-hour study period." | 1.36 | Antibiotic lock: in vitro stability of gentamicin and sodium citrate stored in dialysis catheters at 37 degrees C. ( Battistella, M; Cote, D; Lok, CE; Vercaigne, LM, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (13.16) | 29.6817 |
| 2010's | 31 (81.58) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Caetano, CP | 1 |
| Cassimiro, VP | 1 |
| Dionisio, DL | 1 |
| Pereira, VP | 1 |
| Rodrigues, EAC | 1 |
| Rosa, PN | 1 |
| Elias, DA | 1 |
| Ponce, D | 3 |
| Hussein, WF | 1 |
| Gomez, N | 1 |
| Sun, SJ | 1 |
| Yu, J | 1 |
| Yang, F | 1 |
| Ajuria, M | 1 |
| Abra, GE | 1 |
| Schiller, B | 2 |
| Tsai, CC | 1 |
| Yang, PS | 1 |
| Liu, CL | 1 |
| Wu, CJ | 1 |
| Hsu, YC | 1 |
| Cheng, SP | 1 |
| Goh, TL | 1 |
| Wei, J | 1 |
| Semple, D | 1 |
| Collins, J | 1 |
| Martin, TCS | 1 |
| Abdelmalek, J | 1 |
| Yee, B | 1 |
| Lavergne, S | 1 |
| Ritter, M | 1 |
| Henly, EL | 1 |
| Dowling, JAR | 1 |
| Maingay, JB | 1 |
| Lacey, MM | 1 |
| Smith, TJ | 1 |
| Forbes, S | 1 |
| Visek, J | 1 |
| Ryskova, L | 1 |
| Safranek, R | 1 |
| Lasticova, M | 1 |
| Blaha, V | 1 |
| Guisado-Gil, AB | 1 |
| Herrera-Hidalgo, L | 1 |
| Santos-Rubio, MD | 1 |
| Gil-Sacaluga, L | 1 |
| Molina, J | 1 |
| Lepe-Jiménez, JA | 1 |
| Camacho-Martínez, P | 1 |
| Gil-Navarro, MV | 1 |
| Bueloni, TNV | 1 |
| Marchi, D | 1 |
| Caetano, C | 1 |
| de Souza Cavalcante, R | 1 |
| Mendes Amaral, ML | 1 |
| Padilla-Orozco, M | 1 |
| Mendoza-Flores, L | 1 |
| Herrera-Alonso, A | 1 |
| Garza González, E | 1 |
| Gutiérrez Ferman, JL | 1 |
| Rodríguez-López, JM | 1 |
| Bocanegra-Ibarias, P | 1 |
| Camacho-Ortiz, A | 1 |
| Polese, L | 1 |
| Borrelli, S | 1 |
| Conte, G | 1 |
| De Nicola, L | 1 |
| Minutolo, R | 1 |
| Vita, C | 1 |
| Peruzzu, N | 1 |
| Netti, A | 1 |
| De Stefano, T | 1 |
| Provenzano, M | 1 |
| Garofalo, C | 1 |
| Al-Hwiesh, AK | 1 |
| Abdul-Rahman, IS | 1 |
| Al-Muhanna, FA | 1 |
| Al-Sulaiman, MH | 1 |
| Al-Jondebi, MS | 1 |
| Divino-Filho, JC | 1 |
| Sayet, G | 1 |
| Sinegre, M | 1 |
| Ben Reguiga, M | 1 |
| Lebeaux, D | 3 |
| Chauhan, A | 2 |
| Létoffé, S | 1 |
| Fischer, F | 1 |
| de Reuse, H | 1 |
| Beloin, C | 3 |
| Ghigo, JM | 3 |
| Moore, CL | 1 |
| Besarab, A | 1 |
| Ajluni, M | 1 |
| Soi, V | 1 |
| Peterson, EL | 1 |
| Johnson, LE | 1 |
| Zervos, MJ | 1 |
| Adams, E | 1 |
| Yee, J | 1 |
| Landry, D | 1 |
| Braden, G | 1 |
| Leflon-Guibout, V | 1 |
| Taylor, JE | 1 |
| Tan, K | 1 |
| Lai, NM | 1 |
| McDonald, SJ | 1 |
| Fernandez-Gallego, J | 2 |
| Cermeño, L | 1 |
| Rudas, E | 1 |
| Zhang, J | 1 |
| Wang, B | 1 |
| Li, R | 1 |
| Ge, L | 1 |
| Chen, KH | 1 |
| Tian, J | 1 |
| Abbas, SA | 1 |
| Haloob, IA | 1 |
| Taylor, SL | 1 |
| Curry, EM | 1 |
| King, BB | 1 |
| Van der Merwe, WM | 1 |
| Marshall, MR | 1 |
| Zhang, P | 1 |
| Yuan, J | 1 |
| Tan, H | 1 |
| Lv, R | 1 |
| Chen, J | 1 |
| Bookstaver, PB | 1 |
| Williamson, JC | 1 |
| Tucker, BK | 1 |
| Raad, II | 1 |
| Sherertz, RJ | 1 |
| Polaschegg, HD | 1 |
| Mahaldar, A | 1 |
| Weisz, M | 1 |
| Kathuria, P | 1 |
| Venditto, M | 1 |
| du Montcel, ST | 1 |
| Robert, J | 1 |
| Trystam, D | 1 |
| Dighiero, J | 1 |
| Hue, D | 1 |
| Bessette, C | 1 |
| Deray, G | 1 |
| Mercadal, L | 1 |
| Battistella, M | 1 |
| Vercaigne, LM | 1 |
| Cote, D | 1 |
| Lok, CE | 1 |
| van Nieuwkoop, C | 1 |
| den Exter, PL | 1 |
| Elzevier, HW | 1 |
| den Hartigh, J | 1 |
| van Dissel, JT | 1 |
| Landry, DL | 1 |
| Braden, GL | 1 |
| Gobeille, SL | 1 |
| Haessler, SD | 1 |
| Vaidya, CK | 1 |
| Sweet, SJ | 1 |
| Chow, KM | 1 |
| Poon, YL | 1 |
| Lam, MP | 1 |
| Poon, KL | 1 |
| Szeto, CC | 1 |
| Li, PK | 1 |
| Mazumder, SA | 1 |
| Cleveland, KO | 1 |
| Conde Rivera, O | 1 |
| Santos Nores, J | 1 |
| Borrajo Prol, M | 1 |
| Pérez Melón, C | 1 |
| Filiopoulos, V | 1 |
| Hadjiyannakos, D | 1 |
| Koutis, I | 1 |
| Trompouki, S | 1 |
| Micha, T | 1 |
| Lazarou, D | 1 |
| Vlassopoulos, D | 1 |
| Martín, M | 1 |
| Gutiérrez, E | 1 |
| Cobelo, C | 1 |
| Frías, P | 1 |
| Jironda, C | 1 |
| Hidalgo, P | 1 |
| Jiménez, T | 1 |
| Moran, J | 1 |
| Sun, S | 1 |
| Khababa, I | 1 |
| Pedan, A | 1 |
| Doss, S | 1 |
| Liotta, RF | 1 |
| Tarantino, ML | 1 |
| Silva, TN | 1 |
| Mendes, ML | 1 |
| Abrão, JM | 1 |
| Caramori, JT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Efficacy of Prophylactic Topical Gentamicin in Tunnelled Catheters for Hemodialysis: a Randomized, Double-blind Clinical Trial[NCT04967859] | Phase 1 | 90 participants (Actual) | Interventional | 2018-07-01 | Completed | ||
| Sodium Citrate 4% Locking Solution for Children Requiring Home Parenteral Nutrition[NCT04756427] | Phase 4 | 1 participants (Actual) | Interventional | 2022-03-28 | Completed | ||
| Prospective, Randomized, Controlled Trial Evaluating the Efficacy of a Lock-therapy With a Solution of Taurolidine/Citrate (TauroLock) vs Standard Saline Solution for the Primary Prevention of Catheter-related Infections (CLI) in Adult Patients Wtih a Non[NCT02279121] | 162 participants (Actual) | Interventional | 2014-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for gentamicin and Catheter-Associated Infections
| Article | Year |
|---|---|
Comparison of topical mupirocin and gentamicin in the prevention of peritoneal dialysis-related infections: A systematic review and meta-analysis.
Topics: Administration, Topical; Anti-Bacterial Agents; Antibiotic Prophylaxis; Catheter-Related Infections; | 2018 |
Pasteurella multocida line infection: a case report and review of literature.
Topics: Animals; Anti-Bacterial Agents; Bacteremia; Bites and Stings; Catheter-Related Infections; Cats; Cef | 2018 |
Antibiotic lock for the prevention of catheter-related infection in neonates.
Topics: Amoxicillin; Anti-Bacterial Agents; Catheter-Related Infections; Catheterization, Central Venous; Ce | 2015 |
Does antimicrobial lock solution reduce catheter-related infections in hemodialysis patients with central venous catheters? A Bayesian network meta-analysis.
Topics: Adult; Anti-Infective Agents; Anticoagulants; Bayes Theorem; Catheter-Related Infections; Central Ve | 2017 |
Intravesical gentamicin for recurrent urinary tract infection in patients with intermittent bladder catheterisation.
Topics: Aged; Anti-Bacterial Agents; Catheter-Related Infections; Clinical Trials as Topic; Drug Resistance, | 2010 |
6 trials available for gentamicin and Catheter-Associated Infections
| Article | Year |
|---|---|
Topical gentamicin for the prevention of tunneled hemodialysis catheter-related infections: a randomized double-blind study.
Topics: Aged; Catheter-Related Infections; Catheterization, Central Venous; Catheters, Indwelling; Double-Bl | 2023 |
Cefazolin-gentamicin versus taurolidine-citrate for the prevention of infection in tunneled central catheters in hemodialysis patients: A quasi-experimental trial.
Topics: Adult; Aged; Anti-Bacterial Agents; Catheter-Related Infections; Cefazolin; Central Venous Catheters | 2019 |
Successful prevention of cuffed hemodialysis catheter-related infection using an antibiotic lock technique by strictly catheter-restricted antibiotic lock solution method.
Topics: Adult; Aged; Catheter-Related Infections; Catheters, Indwelling; Female; Gentamicins; Heparin; Human | 2009 |
Approaches to prolong the use of uncuffed hemodialysis catheters: results of a randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anticoagulants; Catheter-Related Infections; | 2011 |
A randomized trial comparing gentamicin/citrate and heparin locks for central venous catheters in maintenance hemodialysis patients.
Topics: Anti-Bacterial Agents; Anticoagulants; Catheter-Related Infections; Catheterization, Central Venous; | 2012 |
[Clean vesical intermittent catheterization: lubrication of vesical catheter through lidocaine or gentamicine?].
Topics: Antibiotic Prophylaxis; Asymptomatic Diseases; Bacteriuria; Catheter-Related Infections; Enterobacte | 2012 |
27 other studies available for gentamicin and Catheter-Associated Infections
| Article | Year |
|---|---|
Use of a gentamicin-citrate lock leads to lower catheter-related bloodstream infection rates and reduced cost of care in hemodialysis patients.
Topics: Catheter-Related Infections; Catheterization, Central Venous; Central Venous Catheters; Citrates; Ci | 2021 |
The incidence and costs of bacteremia due to lack of gentamicin lock solutions for dialysis catheters.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Catheters, Indwelling; | 2017 |
Biocide Exposure Induces Changes in Susceptibility, Pathogenicity, and Biofilm Formation in Uropathogenic
Topics: Animals; Anti-Bacterial Agents; Benzalkonium Compounds; Biguanides; Biofilms; Catheter-Related Infec | 2019 |
In vitro comparison of efficacy of catheter locks in the treatment of catheter related blood stream infection.
Topics: Anti-Bacterial Agents; Bacteremia; Candida; Catheter-Related Infections; Colony Count, Microbial; Eq | 2019 |
Gentamicin as Empirical Treatment in Hemodialysis Patients: Safety, Pharmacokinetics, and Pharmacodynamics.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Fema | 2019 |
Generalized and Prolonged Use of Gentamicin-Lock Therapy Reduces Hemodialysis Catheter-Related Infections Due to Gram Negatives.
Topics: Adult; Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Catheters, Indwelling; Cohort | 2019 |
[Peritoneal dialysis catheter infection with abscess of the abdominal wall in a ADPKD patient].
Topics: Abdominal Wall; Abscess; Anti-Bacterial Agents; Catheter-Related Infections; Combined Modality Thera | 2019 |
Prevention of peritoneal dialysis catheter infections in Saudi peritoneal dialysis patients: the emergence of high-level mupirocin resistance.
Topics: Administration, Cutaneous; Adult; Aged; Anti-Bacterial Agents; Catheter-Related Infections; Catheter | 2013 |
Development of a Fourier transform infrared spectroscopy coupled to UV-Visible analysis technique for aminosides and glycopeptides quantitation in antibiotic locks.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Calibration; Catheter-Related Infections; Catheter | 2014 |
pH-mediated potentiation of aminoglycosides kills bacterial persisters and eradicates in vivo biofilms.
Topics: Animals; Anti-Bacterial Agents; Arginine; Biofilms; Catheter-Related Infections; Central Venous Cath | 2014 |
Comparative effectiveness of two catheter locking solutions to reduce catheter-related bloodstream infection in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anticoagulants; Bacteremia; Catheter-Related | 2014 |
Reducing catheter-related infections in hemodialysis patients.
Topics: Anti-Bacterial Agents; Catheter-Related Infections; Catheterization, Central Venous; Catheters, Indw | 2014 |
In vitro activity of gentamicin, vancomycin or amikacin combined with EDTA or l-arginine as lock therapy against a wide spectrum of biofilm-forming clinical strains isolated from catheter-related infections.
Topics: Amikacin; Anti-Infective Agents; Arginine; Bacteria; Biofilms; Catheter-Related Infections; Chelatin | 2015 |
Gentamicin-based prophylaxis in tunnelled indwelling central venous catheter limbs for haemodialysis do not result in bacterial resistances after a 9 year follow up period.
Topics: Adult; Aged; Aged, 80 and over; Antibiotic Prophylaxis; Catheter-Related Infections; Catheters, Indw | 2015 |
Effect of antimicrobial locks for tunneled hemodialysis catheters on bloodstream infection and bacterial resistance: a quality improvement report.
Topics: Aged; Anti-Bacterial Agents; Catheter-Related Infections; Catheters, Indwelling; Cross-Sectional Stu | 2009 |
Activity of novel antibiotic lock solutions in a model against isolates of catheter-related bloodstream infections.
Topics: Anti-Bacterial Agents; Anticoagulants; Catheter-Related Infections; Catheterization, Central Venous; | 2009 |
Loss of catheter lock fluid is caused by hydraulic effects and not by diffusion.
Topics: Adult; Aged; Catheter-Related Infections; Catheters, Indwelling; Female; Gentamicins; Heparin; Human | 2009 |
Comparison of gentamicin and mupirocin in the prevention of exit-site infection and peritonitis in peritoneal dialysis.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylax | 2009 |
Effect of catheter-lock solutions on catheter-related infection and inflammatory syndrome in hemodialysis patients: heparin versus citrate 46% versus heparin/gentamicin.
Topics: Aged; Anti-Bacterial Agents; C-Reactive Protein; Catheter-Related Infections; Catheterization, Centr | 2010 |
Antibiotic lock: in vitro stability of gentamicin and sodium citrate stored in dialysis catheters at 37 degrees C.
Topics: Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Cit | 2010 |
Emergence of gentamicin-resistant bacteremia in hemodialysis patients receiving gentamicin lock catheter prophylaxis.
Topics: Ambulatory Care; Anti-Bacterial Agents; Antibiotic Prophylaxis; Anticoagulants; Catheter-Related Inf | 2010 |
Antibiotic lock solutions for the prevention of catheter-related bacteraemia in haemodialysis patients.
Topics: Adult; Aged; Anti-Bacterial Agents; Anticoagulants; Bacteremia; Catheter-Related Infections; Cathete | 2010 |
Bordetella bronchiseptica bacteremia in a patient with AIDS.
Topics: Adult; AIDS-Associated Nephropathy; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Ba | 2010 |
[Importance of exit site care as peritonitis prophylaxis: experience in our centre].
Topics: Administration, Topical; Antibiotic Prophylaxis; Candidiasis; Catheter-Related Infections; Catheters | 2010 |
Prophylaxis with gentamicin locking of chronic tunnelled central venous catheters does not cause bacterial resistance.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Cath | 2011 |
Full and broad-spectrum in vivo eradication of catheter-associated biofilms using gentamicin-EDTA antibiotic lock therapy.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Biofilms; Catheter-Related Infections; Catheters; Edetic A | 2012 |
Successful prevention of tunneled central catheter infection by antibiotic lock therapy using cefazolin and gentamicin.
Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Catheter-Related Infections; Cefazolin; | 2013 |