gentamicin has been researched along with Cancer of Rectum in 21 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A previous randomized study conducted by our group showed that application of gentamicin-collagen implant (GCI) into the pelvic cavity after total mesorectal excision (TME) reduced the incidence of distant metastases." | 9.27 | The gentamicin-collagen implant and the risk of distant metastases of rectal cancer following short-course radiotherapy and curative resection: the long-term outcomes of a randomized study. ( Bednarczyk, M; Bujko, K; Hevelke, P; Kryński, J; Olesiński, T; Pierzankowski, I; Pietrzak, L; Rutkowski, A; Saramak, P; Surowski, P; Szpakowski, M; Zając, L, 2018) |
| "A previous randomized study conducted by our group showed that application of gentamicin-collagen implant (GCI) into the pelvic cavity after total mesorectal excision (TME) reduced the incidence of distant metastases." | 5.27 | The gentamicin-collagen implant and the risk of distant metastases of rectal cancer following short-course radiotherapy and curative resection: the long-term outcomes of a randomized study. ( Bednarczyk, M; Bujko, K; Hevelke, P; Kryński, J; Olesiński, T; Pierzankowski, I; Pietrzak, L; Rutkowski, A; Saramak, P; Surowski, P; Szpakowski, M; Zając, L, 2018) |
| "In patients without anastomotic leakage, the risk of organ space SSI was significantly reduced in patients who received GCI: 2." | 2.79 | Surgical site infections following short-term radiotherapy and total mesorectal excision: results of a randomized study examining the role of gentamicin collagen implant in rectal cancer surgery. ( Bednarczyk, M; Byszek, A; Chwalinski, M; Oledzki, J; Olesiński, T; Pietrzak, L; Rutkowski, A; Saramak, P; Szpakowski, M; Zając, L, 2014) |
| "112 patients with primary rectal cancer were enrolled in this study." | 2.77 | Local antibiotic therapy in rectal cancer surgery. ( Dziki, A; Kołacińska, A; Morawiec, Z; Pawlak, M, 2012) |
| "Gentamicin-PMMA chains have been demonstrated to exert a favorable effect on local wound healing and the postoperative outcome of patients with abdominoperineal rectum excision." | 2.67 | Local gentamicin application for perineal wound healing following abdominoperineal rectum excision. ( Czerwenka, E; Marczell, AP; Rosen, HR; Spoula, H; Stierer, MO; Wasl, H, 1991) |
| "Gentamicin was administered using sponges (n = 3), beads (n = 4), and by local injection (n = 1)." | 2.52 | Local Application of Gentamicin in the Prophylaxis of Perineal Wound Infection After Abdominoperineal Resection: A Systematic Review. ( Bemelman, WA; Burger, JW; Buskens, CJ; Musters, GD; Tanis, PJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 11 (52.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frumkin, J | 1 |
| Rutkowski, A | 3 |
| Pietrzak, L | 2 |
| Kryński, J | 1 |
| Zając, L | 2 |
| Bednarczyk, M | 2 |
| Olesiński, T | 2 |
| Szpakowski, M | 2 |
| Saramak, P | 2 |
| Pierzankowski, I | 1 |
| Hevelke, P | 1 |
| Surowski, P | 1 |
| Bujko, K | 1 |
| Michalik, T | 1 |
| Matkowski, R | 2 |
| Biecek, P | 1 |
| Forgacz, J | 2 |
| Szynglarewicz, B | 2 |
| Ekiert, M | 1 |
| Byszek, A | 1 |
| Oledzki, J | 2 |
| Chwalinski, M | 2 |
| Biondo, S | 1 |
| Musters, GD | 1 |
| Burger, JW | 1 |
| Buskens, CJ | 1 |
| Bemelman, WA | 1 |
| Tanis, PJ | 1 |
| de Bruin, AF | 1 |
| Gosselink, MP | 1 |
| Wijffels, NA | 1 |
| Coene, PP | 1 |
| van der Harst, E | 1 |
| Ruiz-Tovar, J | 1 |
| Santos, J | 1 |
| Arroyo, A | 1 |
| Llavero, C | 1 |
| Armañanzas, L | 1 |
| López-Delgado, A | 1 |
| Frangi, A | 1 |
| Alcaide, MJ | 1 |
| Candela, F | 1 |
| Calpena, R | 1 |
| Collin, Å | 1 |
| Gustafsson, UM | 1 |
| Smedh, K | 1 |
| Påhlman, L | 1 |
| Graf, W | 1 |
| Folkesson, J | 1 |
| Goodwin, ML | 1 |
| Morawiec, Z | 1 |
| Pawlak, M | 1 |
| Kołacińska, A | 1 |
| Dziki, A | 1 |
| Nowacki, MP | 1 |
| Nagy, A | 1 |
| Horpacsy, G | 1 |
| Vecsei, B | 1 |
| Baradnay, G | 1 |
| Laitinen, S | 1 |
| Huttunen, R | 1 |
| Ståhlberg, M | 1 |
| Mokka, R | 1 |
| Kairaluoma, M | 1 |
| Larmi, TK | 1 |
| Gruessner, U | 1 |
| Clemens, M | 1 |
| Pahlplatz, PV | 1 |
| Sperling, P | 1 |
| Witte, J | 1 |
| Rosen, HR | 2 |
| Feathers, RS | 1 |
| Sagor, GR | 1 |
| Lewis, AA | 1 |
| Amirak, ID | 1 |
| Noone, P | 1 |
| Cai, CJ | 1 |
| Marczell, AP | 1 |
| Czerwenka, E | 1 |
| Stierer, MO | 1 |
| Spoula, H | 1 |
| Wasl, H | 1 |
| Lau, WY | 1 |
| Chu, KW | 1 |
| Poon, GP | 1 |
| Ho, KK | 1 |
| Talpacci, A | 1 |
| Destradis, E | 1 |
| Rogati, L | 1 |
| Rulli, A | 1 |
| Tristaino, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PROTOP: Study of the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Localization Infection in Colorectal Surgery[NCT03574090] | Phase 4 | 268 participants (Actual) | Interventional | 2020-10-20 | Completed | ||
| Effect of Peritoneal Lavage With Clindamycin-gentamicin Solution on Infection in Elective Surgery[NCT01378832] | Phase 3 | 102 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| A Novel Wound Retractor Combining Continuous Irrigation and Barrier Protection Reduces Incisional Contamination and Surgical Site Infection in Colorectal Surgery[NCT03816995] | 702 participants (Anticipated) | Interventional | 2019-02-12 | Recruiting | |||
| Secondary Intention Wound Healing, in Patients Subjected to Surgical Resection of Pilonidal Cyst, Using Alginate Dressings With Silver and High-G Cellulose, Compared to the Use of Simple Gauze Dressings: Examination of the Quality of Life[NCT03757572] | 65 participants (Actual) | Interventional | 2018-12-25 | Terminated (stopped due to Early termination due to COVID-19 pandemic. Suspension of elective case operations. Decreased recruitment rate. Inability to reach the estimated sample size.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for gentamicin and Cancer of Rectum
| Article | Year |
|---|---|
Local Application of Gentamicin in the Prophylaxis of Perineal Wound Infection After Abdominoperineal Resection: A Systematic Review.
Topics: Abdomen; Anti-Bacterial Agents; Antibiotic Prophylaxis; Gentamicins; Humans; Perineum; Rectal Neopla | 2015 |
11 trials available for gentamicin and Cancer of Rectum
| Article | Year |
|---|---|
The gentamicin-collagen implant and the risk of distant metastases of rectal cancer following short-course radiotherapy and curative resection: the long-term outcomes of a randomized study.
Topics: Adenocarcinoma; Aged; Anti-Bacterial Agents; Collagen; Disease-Free Survival; Female; Gentamicins; H | 2018 |
Surgical site infections following short-term radiotherapy and total mesorectal excision: results of a randomized study examining the role of gentamicin collagen implant in rectal cancer surgery.
Topics: Adult; Aged; Aged, 80 and over; Anastomotic Leak; Anti-Bacterial Agents; Collagen; Combined Modality | 2014 |
Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery.
Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Digestive System Sur | 2012 |
Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery.
Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Digestive System Sur | 2012 |
Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery.
Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Digestive System Sur | 2012 |
Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery.
Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Digestive System Sur | 2012 |
Effect of local gentamicin-collagen on perineal wound complications and cancer recurrence after abdominoperineal resection: a multicentre randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Collagen; Drug Combinations; Female; Follow-U | 2013 |
Local antibiotic therapy in rectal cancer surgery.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Anti-Bacterial Agent | 2012 |
Prospective, randomized trial examining the role of gentamycin-containing collagen sponge in the reduction of postoperative morbidity in rectal cancer patients: early results and surprising outcome at 3-year follow-up.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Collagen | 2005 |
Improvement of perineal wound healing by local administration of gentamicin-impregnated collagen fleeces after abdominoperineal excision of rectal cancer.
Topics: Absorbable Implants; Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; | 2001 |
Prophylactic systemic antibiotics in colorectal surgery.
Topics: Abscess; Adult; Aged; Bacteroides fragilis; Clinical Trials as Topic; Colitis; Colon; Colonic Neopla | 1977 |
[Clinical study of prophylactic use of gentamicin and metronidazole in the surgery of colorectal carcinoma].
Topics: Colonic Neoplasms; Female; Gentamicins; Humans; Male; Metronidazole; Middle Aged; Premedication; Pro | 1992 |
Local gentamicin application for perineal wound healing following abdominoperineal rectum excision.
Topics: Administration, Rectal; Adult; Aged; Aged, 80 and over; Anus Neoplasms; Colorectal Surgery; Female; | 1991 |
Prophylactic antibiotics in elective colorectal surgery.
Topics: Administration, Oral; Anti-Bacterial Agents; Colon; Colonic Neoplasms; Erythromycin; Female; Gentami | 1988 |
9 other studies available for gentamicin and Cancer of Rectum
| Article | Year |
|---|---|
Gentamicin, a read-through agent for the treatment of rectal cancer.
Topics: Gentamicins; Humans; Rectal Neoplasms; Rectum | 2017 |
Ultralow anterior resection with implantation of gentamicin-collagen sponge and no defunctioning stoma: anastomotic leakage and local cancer relapse.
Topics: Adult; Aged; Aged, 80 and over; Anastomotic Leak; Collagen; Drug Implants; Female; Gentamicins; Huma | 2019 |
Can gentamicin-containing collagen sponge be used for the protection against leakage following low anterior resection with total mesorectal excision?
Topics: Anastomotic Leak; Animals; Anti-Bacterial Agents; Collagen; Digestive System Surgical Procedures; Fo | 2014 |
Prevention of surgical site infection: still an important challenge in colorectal surgery.
Topics: Anti-Bacterial Agents; Female; Gentamicins; Humans; Male; Rectal Neoplasms; Surgical Wound Infection | 2014 |
Local gentamicin reduces perineal wound infection after radiotherapy and abdominoperineal resection.
Topics: Abdomen; Aged; Aged, 80 and over; Anti-Bacterial Agents; Combined Modality Therapy; Female; Gentamic | 2008 |
Control, control, control; where's your control?
Topics: Abdominal Abscess; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Female; Gentamicins; Human | 2012 |
[Urinary enzyme excretion after prophylactic antibiotic therapy in patients following colorectal surgery (author's transl)].
Topics: Acetylglucosaminidase; Alanine Transaminase; Colonic Neoplasms; Drug Therapy, Combination; Gentamici | 1981 |
Experiences with the EEA stapling instrument for colorectal anastomosis.
Topics: Adult; Aged; Clindamycin; Colectomy; Colon; Colonic Neoplasms; Disposable Equipment; Female; Gentami | 1980 |
[Infectious complications in colo-rectal surgery: how to prevent them?].
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefotetan; Cephalosporins; Clindamycin; Colonic Neoplas | 1988 |