Page last updated: 2024-10-27

gentamicin and Cancer of Colon

gentamicin has been researched along with Cancer of Colon in 15 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
"Internalization of bacteria from HIV/AIDS patients frequently resulted in partial (patients SKM1, SKM22) or complete lysis (patients SKK1-1, SKM12) of HL-60 cells."1.43Internalization property of intestinal bacteria in colon cancer and HIV/AIDS patients. ( Ciernikova, S; Majek, J; Mego, M; Stevurkova, V; Wachsmannova, L; Zajac, V, 2016)
" The optimized population model allowed us to simulate drug serum levels at 8 and 12h, as well as the area under the curve of gentamicin and its variability in patients with high distribution volumes when dosage regimens based on a single daily dose administration are implemented."1.30Influence of diagnostic and treatment factors in the population pharmacokinetics of gentamicin. ( Aguado, JM; Antón, J; González, P; Lanao, JM; Romano, S; Tejada, P, 1998)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19907 (46.67)18.7374
1990's4 (26.67)18.2507
2000's1 (6.67)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wachsmannova, L1
Ciernikova, S1
Majek, J1
Mego, M1
Stevurkova, V1
Zajac, V1
Ruiz-Tovar, J1
Santos, J1
Arroyo, A1
Llavero, C1
Armañanzas, L1
López-Delgado, A1
Frangi, A1
Alcaide, MJ1
Candela, F1
Calpena, R1
Goodwin, ML1
Chen, SC1
Lin, MF1
Nagy, A2
Vécsei, B2
Horpácsy, G2
Baradnay, G2
Laitinen, S1
Huttunen, R1
Ståhlberg, M1
Mokka, R1
Kairaluoma, M1
Larmi, TK1
Marais, R1
Spooner, RA1
Light, Y1
Martin, J1
Springer, CJ1
Romano, S1
González, P1
Tejada, P1
Antón, J1
Aguado, JM1
Lanao, JM1
Hausner, P1
Venzon, DJ1
Grogan, L1
Kirsch, IR1
Feathers, RS1
Sagor, GR1
Lewis, AA1
Amirak, ID1
Noone, P1
Cai, CJ1
Lau, WY1
Chu, KW1
Poon, GP1
Ho, KK1
Talpacci, A1
Destradis, E1
Rogati, L1
Rulli, A1
Tristaino, B1
Poretz, DM1
Wood, L1
Park, C1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Peritoneal Lavage With Clindamycin-gentamicin Solution on Infection in Elective Surgery[NCT01378832]Phase 3102 participants (Actual)Interventional2010-01-31Completed
A Novel Wound Retractor Combining Continuous Irrigation and Barrier Protection Reduces Incisional Contamination and Surgical Site Infection in Colorectal Surgery[NCT03816995]702 participants (Anticipated)Interventional2019-02-12Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for gentamicin and Cancer of Colon

ArticleYear
Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery.
    Journal of the American College of Surgeons, 2012, Volume: 214, Issue:2

    Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Digestive System Sur

2012
Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery.
    Journal of the American College of Surgeons, 2012, Volume: 214, Issue:2

    Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Digestive System Sur

2012
Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery.
    Journal of the American College of Surgeons, 2012, Volume: 214, Issue:2

    Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Digestive System Sur

2012
Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery.
    Journal of the American College of Surgeons, 2012, Volume: 214, Issue:2

    Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Digestive System Sur

2012
Prophylactic systemic antibiotics in colorectal surgery.
    Lancet (London, England), 1977, Jul-02, Volume: 2, Issue:8027

    Topics: Abscess; Adult; Aged; Bacteroides fragilis; Clinical Trials as Topic; Colitis; Colon; Colonic Neopla

1977
[Clinical study of prophylactic use of gentamicin and metronidazole in the surgery of colorectal carcinoma].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1992, Volume: 30, Issue:4

    Topics: Colonic Neoplasms; Female; Gentamicins; Humans; Male; Metronidazole; Middle Aged; Premedication; Pro

1992
Prophylactic antibiotics in elective colorectal surgery.
    The British journal of surgery, 1988, Volume: 75, Issue:8

    Topics: Administration, Oral; Anti-Bacterial Agents; Colon; Colonic Neoplasms; Erythromycin; Female; Gentami

1988

Other Studies

11 other studies available for gentamicin and Cancer of Colon

ArticleYear
Internalization property of intestinal bacteria in colon cancer and HIV/AIDS patients.
    Neuro endocrinology letters, 2016, Volume: 37, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Bacterial Agents; Bacteria; Colonic Neoplasms; Color

2016
Control, control, control; where's your control?
    Journal of the American College of Surgeons, 2012, Volume: 215, Issue:3

    Topics: Abdominal Abscess; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Female; Gentamicins; Human

2012
Favorable outcome of infective endocarditis due to Streptococcus agalactiae after conservative treatment.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2004, Volume: 37, Issue:5

    Topics: Aged; Aged, 80 and over; Colonic Neoplasms; Drug Therapy, Combination; Endocarditis, Bacterial; Fema

2004
[Changes in kidney function in patients with colon tumors treated with nephrotoxic antibiotics].
    Orvosi hetilap, 1981, Apr-12, Volume: 122, Issue:15

    Topics: Antibiotics, Antineoplastic; Colonic Neoplasms; Gentamicins; Humans; Kidney; Kidney Function Tests;

1981
[Urinary enzyme excretion after prophylactic antibiotic therapy in patients following colorectal surgery (author's transl)].
    Wiener klinische Wochenschrift, 1981, Oct-30, Volume: 93, Issue:20

    Topics: Acetylglucosaminidase; Alanine Transaminase; Colonic Neoplasms; Drug Therapy, Combination; Gentamici

1981
Experiences with the EEA stapling instrument for colorectal anastomosis.
    Annales chirurgiae et gynaecologiae, 1980, Volume: 69, Issue:3

    Topics: Adult; Aged; Clindamycin; Colectomy; Colon; Colonic Neoplasms; Disposable Equipment; Female; Gentami

1980
Gene-directed enzyme prodrug therapy with a mustard prodrug/carboxypeptidase G2 combination.
    Cancer research, 1996, Oct-15, Volume: 56, Issue:20

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Colonic Neoplasms; COS Cells; Drug Screening

1996
Influence of diagnostic and treatment factors in the population pharmacokinetics of gentamicin.
    Journal of clinical pharmacy and therapeutics, 1998, Volume: 23, Issue:2

    Topics: Abscess; Adult; Appendicitis; Cholecystitis; Colonic Neoplasms; Drug Interactions; Female; Gentamici

1998
The "comparative growth assay": examining the interplay of anti-cancer agents with cells carrying single gene alterations.
    Neoplasia (New York, N.Y.), 1999, Volume: 1, Issue:4

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member

1999
[Infectious complications in colo-rectal surgery: how to prevent them?].
    Minerva chirurgica, 1988, Oct-15, Volume: 43, Issue:19

    Topics: Anti-Bacterial Agents; Bacterial Infections; Cefotetan; Cephalosporins; Clindamycin; Colonic Neoplas

1988
Adenocarcinoma of the colon presenting as Clostridium septicum cellulitis of the left thigh.
    Southern medical journal, 1974, Volume: 67, Issue:7

    Topics: Adenocarcinoma; Aged; Cellulitis; Chloramphenicol; Clostridium; Clostridium Infections; Colonic Neop

1974