Page last updated: 2024-10-27

gentamicin and Brucellosis

gentamicin has been researched along with Brucellosis in 72 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Brucellosis: Infection caused by bacteria of the genus BRUCELLA mainly involving the MONONUCLEAR PHAGOCYTE SYSTEM. This condition is characterized by fever, weakness, malaise, and weight loss.

Research Excerpts

ExcerptRelevanceReference
"This prospective, non-randomized trial, compared the efficacy and tolerance of a doxycycline-rifampin regimen, administered for 45 days, versus doxycycline-rifampin given for 45 days plus gentamicin for the first 7-10 days, in the treatment of human brucellosis."9.16Doxycycline-rifampin versus doxycycline-rifampin-gentamicin in treatment of human brucellosis. ( Ilir, D; Ivan, V; Krsto, G; Mile, B; Nikola, L; Valerija, K, 2012)
"To compare the efficacy of gentamicin for 5 days plus doxycycline for 8 weeks with streptomycin for 2 weeks plus doxycycline for 45 days in the treatment of human brucellosis."9.14Comparison of the efficacy of gentamicin for 5 days plus doxycycline for 8 weeks versus streptomycin for 2 weeks plus doxycycline for 45 days in the treatment of human brucellosis: a randomized clinical trial. ( Amiri, MJ; Baiani, M; Bijani, A; Hadad, MS; Janmohammadi, N; Javanian, M; Roushan, MR, 2010)
"The objective of the present prospective, noncomparative, multicenter study was assess the safety and efficacy of gentamicin and doxycycline therapy for human brucellosis."9.08Treatment of human brucellosis with doxycycline and gentamicin. ( Escribano, J; Espinosa, A; Fernández, JA; Geijo, P; Martínez-Alfaro, E; Navarro, E; Sánchez, L; Solera, J, 1997)
"Ten patients with brucellosis were treated with azithromycin and gentamicin to assess the treatment's safety and efficacy."7.71Azithromycin and gentamicin therapy for the treatment of humans with brucellosis. ( Beato, JL; de Tomas, E; Martínez-Alfaro, E; Segura, JC; Solera, J, 2001)
"In view of treating intracellular Brucella infections, microspheres made of poly(lactide) (PLA) and poly(lactide-co-glycolide) (PLGA) were developed as delivery system for the cationic and highly hydrophilic antibiotic gentamicin sulphate."7.70Gentamicin encapsulation in PLA/PLGA microspheres in view of treating Brucella infections. ( Gamazo, C; Gander, B; Irache, JM; Merkle, HP; Prior, S, 2000)
"In the treatment of human brucellosis, antibiotic regimens containing an aminoglycoside are reportedly associated with fewer relapses."6.72Efficacy of gentamicin plus doxycycline versus streptomycin plus doxycycline in the treatment of brucellosis in humans. ( Hajiahmadi, M; Hasanjani Roushan, MR; Mohraz, M; Ramzani, A; Valayati, AA, 2006)
"This prospective, non-randomized trial, compared the efficacy and tolerance of a doxycycline-rifampin regimen, administered for 45 days, versus doxycycline-rifampin given for 45 days plus gentamicin for the first 7-10 days, in the treatment of human brucellosis."5.16Doxycycline-rifampin versus doxycycline-rifampin-gentamicin in treatment of human brucellosis. ( Ilir, D; Ivan, V; Krsto, G; Mile, B; Nikola, L; Valerija, K, 2012)
"To compare the efficacy of gentamicin for 5 days plus doxycycline for 8 weeks with streptomycin for 2 weeks plus doxycycline for 45 days in the treatment of human brucellosis."5.14Comparison of the efficacy of gentamicin for 5 days plus doxycycline for 8 weeks versus streptomycin for 2 weeks plus doxycycline for 45 days in the treatment of human brucellosis: a randomized clinical trial. ( Amiri, MJ; Baiani, M; Bijani, A; Hadad, MS; Janmohammadi, N; Javanian, M; Roushan, MR, 2010)
"The objective of the present prospective, noncomparative, multicenter study was assess the safety and efficacy of gentamicin and doxycycline therapy for human brucellosis."5.08Treatment of human brucellosis with doxycycline and gentamicin. ( Escribano, J; Espinosa, A; Fernández, JA; Geijo, P; Martínez-Alfaro, E; Navarro, E; Sánchez, L; Solera, J, 1997)
"The purpose of this study was to investigate renal function in patients with brucellosis before and at the end of gentamicin therapy."4.31Assessing the Risk of Nephrotoxicity Associated with Aminoglycosides in Brucellosis Patients: A Cross-sectional Study. ( Ataei, S; Derakhshandeh, K; Ghodsipour, Z; Keramat, F; Kord, M; Majzoobi, MM; Mohammadi, M; Mohammadi, Y; Nili-Ahmadabadi, A, 2023)
"Gentamicin is used to treat brucellosis, an infectious disease caused by the Brucella species but the drug faces several issues such as low efficacy, instability, low solubility, and toxicity."4.31Interaction of gentamicin and gentamicin-AOT with poly-(lactide-co-glycolate) in a drug delivery system - density functional theory calculations and molecular dynamics simulation. ( Anwar, J; Duran, S; Moin, ST, 2023)
" The patient was treated with doxycycline, rifampicin, and gentamicin, and underwent surgical repair of a penetrating aortic ulcer, with a good clinical recovery."3.80Brucella arteritis: clinical manifestations, treatment, and prognosis. ( Herrick, JA; Lederman, RJ; Palmore, TN; Powers, JH; Sullivan, B, 2014)
"The aim of this study was to assess in vitro antimicrobial susceptibility of Brucella melitensis isolates isolated from naturally infected sheep cases in an area where human brucellosis is endemic, focusing on rifampin (RIF), streptomycin (SM), ciprofloxacin (CPFX), trimethoprim/sulfamethoxazole (TMP/SMZ), gentamicin (GM) and tetracycline (TC) and on 11 other antimicrobials."3.79In vitro antimicrobial susceptibility of Brucella melitensis isolates from sheep in an area endemic for human brucellosis in Turkey. ( Ekin, IH; Ilhan, Z; Solmaz, H, 2013)
"Drug delivery systems containing gentamicin were studied as a treatment against experimental brucellosis in mice."3.74Poly(D,L-lactide-coglycolide) particles containing gentamicin: pharmacokinetics and pharmacodynamics in Brucella melitensis-infected mice. ( Blanco-Prieto, MJ; Campanero, MA; Gamazo, C; Lecaroz, MC; Salman, H, 2007)
"Neither a single intravenous or intraperitoneal dose of 67 microg of gentamicin per mouse, nor three intraperitoneal doses of 100 microg of gentamicin per mouse, reduced the Brucella infection in the spleen compared with untreated mice 1 and 3 weeks post-treatment."3.73Gentamicin-loaded microspheres for treatment of experimental Brucella abortus infection in mice. ( Gamazo, C; Gander, B; Irache, JM; Prior, S, 2005)
"The intracellular antibiotic efficiency of gentamicin-loaded microspheres in the context of Brucella-infected murine monocytes was examined in vitro with a view to developing improved therapies for the treatment of brucellosis."3.72Gentamicin-loaded microspheres for reducing the intracellular Brucella abortus load in infected monocytes. ( Gamazo, C; Gander, B; Irache, JM; Lecároz, C; Prior, S, 2004)
"Ten patients with brucellosis were treated with azithromycin and gentamicin to assess the treatment's safety and efficacy."3.71Azithromycin and gentamicin therapy for the treatment of humans with brucellosis. ( Beato, JL; de Tomas, E; Martínez-Alfaro, E; Segura, JC; Solera, J, 2001)
"In view of treating intracellular Brucella infections, microspheres made of poly(lactide) (PLA) and poly(lactide-co-glycolide) (PLGA) were developed as delivery system for the cationic and highly hydrophilic antibiotic gentamicin sulphate."3.70Gentamicin encapsulation in PLA/PLGA microspheres in view of treating Brucella infections. ( Gamazo, C; Gander, B; Irache, JM; Merkle, HP; Prior, S, 2000)
"Seventy-three cases of acute brucellosis were studied in relation to fever duration and hospital stay following different drug combinations, including gentamicin plus cotrimoxazole, rifampicin plus doxycycline, rifampicin plus cotrimoxazole, rifampicin plus tetracycline, streptomycin plus doxycycline, doxycycline plus cotrimoxazole, tetracycline plus cotrimoxazole, and tetracycline plus streptomycin."3.70Early clinical response to different therapeutic regimens for human brucellosis. ( Malik, GM, 1998)
"Brucellosis is among the most prevalent zoonotic infections in Middle Eastern and North African (MENA) countries, critically impacting human and animal health."2.82The perspective of antibiotic therapeutic challenges of brucellosis in the Middle East and North African countries: Current situation and therapeutic management. ( Al-Talhy, AM; Ali, H; Dadar, M; Elkharsawi, AR; Hamdy, MER; Neubauer, H; Tawab, AAAE; Wareth, G, 2022)
"In the treatment of human brucellosis, antibiotic regimens containing an aminoglycoside are reportedly associated with fewer relapses."2.72Efficacy of gentamicin plus doxycycline versus streptomycin plus doxycycline in the treatment of brucellosis in humans. ( Hajiahmadi, M; Hasanjani Roushan, MR; Mohraz, M; Ramzani, A; Valayati, AA, 2006)
"Brucellosis is the most common worldwide zoonosis which continues to remain a significant worldwide health problem and burden."2.55Brucellar Vertebral Osteomyelitis: A Case Report and Brief Review of the Literature. ( Abrantes-Figueiredo, J; Wu, U, 2017)
"Brucellosis is a chronic disease caused by Brucella species with a wide range of hosts, from marine mammals to terrestrial species, but with strict host preferences."1.91The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged. ( Abay, S; Akar, M; Aydin, F; Balkan Bozlak, CE; Baykal, A; Buyuk, E; Buyuk, F; Celebi, O; Celik, E; Coskun, MR; Durhan, S; Ersoy, Y; Gulmez Saglam, A; Karakaya, E; Kayman, T; Otlu, S; Sahin, M; Saticioglu, IB, 2023)
"Brucellosis is one of the most common diseases that afflicts both humans and animals."1.56The expression of type II TA system genes following exposure to the sub-inhibitory concentration of gentamicin and acid stress in Brucella spp. ( Amraei, F; Lohrasbi, V; Masjedian Jazi, F; Mohammadzadeh, R; Narimisa, N; Sadeghi Kalani, B, 2020)
"While epididymo-orchitis is relatively common in adolescent men, when presented with a significant travel history, consideration should be given to rare causes such as this."1.51Acute epididymo-orchitis from ( Arunasalam, A; Hoh, IM; Ip, CCK; Tumali, K, 2019)
"Thyroiditis was diagnosed with clinical inspection and confirmed by ultrasound investigation."1.51Acute Thyroiditis Associated with Brucellosis: A Case Report. ( Bitoska, I; Bosilkovski, M; Cvetkova, M; Jakimovski, D; Poposki, K, 2019)
"Brucellosis has a low incidence in Chile, thus, we have a scarce data."1.46[Brucellosis in Chile: Description of a series of 13 cases]. ( Cifuentes, M; Luppi, M; Norambuena, M; Olivares, R; Silva, F; Sotomayor, C; Vidal, P, 2017)
"Brucellosis is one of the most common zoonotic disease affecting humans and animals and is endemic in many parts of the world including the Gulf Cooperation Council region (GCC)."1.42In vitro antimicrobial susceptibility testing of human Brucella melitensis isolates from Qatar between 2014 - 2015. ( Abraham, M; Deshmukh, A; Doiphode, S; Hagen, F; Maslamani, MA; Meis, JF; Sharabasi, OA; Wilson, G, 2015)
"Gentamicin formulations reduced Brucella infection in experimentally infected THP-1 monocytes (>2-log10 unit reduction) when using clinically relevant concentrations (18 mg/liter)."1.39Hydrophobic gentamicin-loaded nanoparticles are effective against Brucella melitensis infection in mice. ( Blanco-Prieto, MJ; Campanero, MÁ; Elizondo, E; Gamazo, C; Gil, AG; Imbuluzqueta, E; Lana, H; Salas, D; Veciana, J; Ventosa, N, 2013)
"Neurobrucellosis is an uncommon complication of pediatric brucellosis."1.38Unusual presentations of pediatric neurobrucellosis. ( Budnik, I; Fuchs, I; Greenberg, D; Krymko, H; Shelef, I, 2012)
"Brucellosis is an important public health problem in Peru."1.37Antimicrobial susceptibility of Brucella melitensis isolates in Peru. ( Castillo, R; Cepeda, D; Chacaltana, J; Espinosa, B; Espinoza, N; González, S; Guillen, A; Hall, ER; Maves, RC; Meza, R; Núñez, G; Sánchez, L, 2011)
"Gentamicin (GEN) is an aminoglycoside antibiotic with a potent antibacterial activity against a wide variety of bacteria."1.37Novel bioactive hydrophobic gentamicin carriers for the treatment of intracellular bacterial infections. ( Blanco-Prieto, MJ; Elizondo, E; Gamazo, C; Imbuluzqueta, E; Moreno-Calvo, E; Veciana, J; Ventosa, N, 2011)
"cloxacillin, she was released from hospital with instructions to continue cloxacillin orally for another 4 weeks."1.30[Discitis in brucellosis is not responsive to anti-brucella treatment]. ( Heldenberg, D; Sevi, R, 1998)
"Leukopenia was found in 51% of children and anaemia in 24%."1.30Brucellosis in children in south Jordan. ( Issa, H; Jamal, M, 1999)
"Free gentamicin was less effective than the encapsulated antibiotic."1.28Treatment of Brucella melitensis infection in mice by use of liposome-encapsulated gentamicin. ( Crespo, F; Gómez-Fernández, JC; Hernández-Caselles, T; Vera, A; Villalaín, J, 1989)
" The dosage schedule used involved two intraperitoneal administrations of SPLV-entrapped aminoglycosides at three-day intervals."1.27Treatment of Brucella canis and Brucella abortus in vitro and in vivo by stable plurilamellar vesicle-encapsulated aminoglycosides. ( Fountain, AG; Fountain, MW; Lenk, RP; Shen, A; Weiss, SJ, 1985)

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19909 (12.50)18.7374
1990's11 (15.28)18.2507
2000's17 (23.61)29.6817
2010's27 (37.50)24.3611
2020's8 (11.11)2.80

Authors

AuthorsStudies
Wareth, G1
Dadar, M1
Ali, H1
Hamdy, MER1
Al-Talhy, AM1
Elkharsawi, AR1
Tawab, AAAE1
Neubauer, H1
Al-Faifi, J1
Ibrahim, ME1
Ataei, S1
Ghodsipour, Z1
Keramat, F1
Derakhshandeh, K1
Mohammadi, Y1
Majzoobi, MM1
Kord, M1
Mohammadi, M1
Nili-Ahmadabadi, A1
Duran, S1
Anwar, J1
Moin, ST1
Celik, E1
Kayman, T1
Buyuk, F1
Gulmez Saglam, A1
Abay, S1
Akar, M1
Karakaya, E1
Balkan Bozlak, CE1
Coskun, MR1
Buyuk, E1
Celebi, O1
Sahin, M1
Saticioglu, IB1
Durhan, S1
Baykal, A1
Ersoy, Y1
Otlu, S1
Aydin, F1
Cvetkova, M1
Bitoska, I1
Poposki, K1
Jakimovski, D1
Bosilkovski, M2
Amraei, F1
Narimisa, N1
Sadeghi Kalani, B1
Mohammadzadeh, R1
Lohrasbi, V1
Masjedian Jazi, F1
Ljubas, D1
Lalovac, M1
Vince, A1
Papic, N1
Mousavinasab, SR1
Akhoundi-Meybodi, Z1
Mahmoudi, L1
Karimzadeh, I1
Olivares, R1
Vidal, P1
Sotomayor, C1
Norambuena, M1
Luppi, M1
Silva, F1
Cifuentes, M1
Shevtsov, A1
Syzdykov, M1
Kuznetsov, A1
Shustov, A1
Shevtsova, E1
Berdimuratova, K1
Mukanov, K1
Ramankulov, Y1
Valguarnera, E1
Spera, JM1
Czibener, C1
Fulgenzi, FR1
Casabuono, AC1
Altabe, SG1
Pasquevich, KA1
Guaimas, F1
Cassataro, J1
Couto, AS1
Ugalde, JE1
Elzein, FE1
Al Sherbini, N1
Alotaibi, MM1
Al-Hassan, WM1
Mor, SM1
Wiethoelter, AK1
Massey, PD1
Robson, J1
Wilks, K1
Hutchinson, P1
Abrantes-Figueiredo, J1
Wu, U1
Kanji, JN1
Saxinger, L1
Ip, CCK1
Tumali, K1
Hoh, IM1
Arunasalam, A1
Esmaeilnejad-Ganji, SM1
Roushan, MRH1
Ebrahimpour, S1
Babazadeh, A1
Ilhan, Z1
Solmaz, H1
Ekin, IH1
Imbuluzqueta, E2
Gamazo, C6
Lana, H1
Campanero, MÁ2
Salas, D1
Gil, AG1
Elizondo, E2
Ventosa, N2
Veciana, J2
Blanco-Prieto, MJ3
Jain-Gupta, N1
Contreras-Rodriguez, A1
Smith, GP1
Garg, VK1
Witonsky, SG1
Isloor, S1
Vemulapalli, R1
Boyle, SM1
Sriranganathan, N1
Herrick, JA1
Lederman, RJ1
Sullivan, B1
Powers, JH1
Palmore, TN1
Deshmukh, A1
Hagen, F1
Sharabasi, OA1
Abraham, M1
Wilson, G1
Doiphode, S1
Maslamani, MA1
Meis, JF1
Barbosa Pauletti, R1
Reinato Stynen, AP1
Pinto da Silva Mol, J1
Seles Dorneles, EM1
Alves, TM1
de Sousa Moura Souto, M1
Minharro, S1
Heinemann, MB1
Lage, AP1
Jalan, D1
Elhence, A1
Elhence, P1
Jain, P1
Möllering, N1
Lenhartz, H1
Stegmann, J1
Höger, P1
Dayan, L1
Deyev, S1
Palma, L1
Rozen, N1
Mamalis, IP1
Panagopoulos, MI1
Papanastasiou, DA1
Bricteux, G1
Wolff, T1
Leupold, J1
Nüesch, R1
Reirden, DH1
Menchise, AN1
Knox, B1
Gereige, R1
Howard, T1
Thomas, EL1
Connelly, R1
Tyler, S1
McPeak, K1
Roushan, MR3
Amiri, MJ2
Janmohammadi, N1
Hadad, MS1
Javanian, M1
Baiani, M1
Bijani, A1
Moreno-Calvo, E1
Maves, RC1
Castillo, R1
Guillen, A1
Espinosa, B1
Meza, R1
Espinoza, N1
Núñez, G1
Sánchez, L2
Chacaltana, J1
Cepeda, D1
González, S1
Hall, ER1
Ramin, B1
Macpherson, P1
Mile, B1
Valerija, K1
Krsto, G1
Ivan, V1
Ilir, D1
Nikola, L1
Budnik, I1
Fuchs, I1
Shelef, I1
Krymko, H1
Greenberg, D1
Salvo, S1
Benito, R1
de Gregorio, MA1
Gil, J1
Cuesta, J1
Rubio, C1
Durán, E1
Karabay, O1
Gozdas, HT1
Olivares, D1
Navarro-López, V1
Serrano, R1
López-García, F1
Prior, S3
Gander, B3
Lecároz, C1
Irache, JM3
Hasanjani Roushan, MR1
Mohraz, M1
Hajiahmadi, M1
Ramzani, A1
Valayati, AA1
Paitoonpong, L1
Ekgatat, M1
Nunthapisud, P1
Tantawichien, T1
Suankratay, C1
Lecaroz, MC1
Salman, H1
Sarafidis, K1
Agakidis, C1
Diamanti, E1
Karantaglis, N1
Roilides, E1
Kilicaslan, B1
Cengiz, N1
Pourbagher, MA1
Cemil, T1
Ariza, J1
Cascio, A1
Colmenero, JD2
Corbel, MJ1
Falagas, ME1
Memish, ZA1
Rubinstein, E1
Sipsas, NV1
Solera, J4
Young, EJ1
Pappas, G1
Platt, P1
Gray, J1
Carson, P1
Howell, GE1
Miller, MM1
Rowen, JI1
Englund, JA1
Benjamin, B1
Espinosa, A2
Martínez-Alfaro, E3
Geijo, P1
Navarro, E1
Escribano, J1
Fernández, JA1
Sánchez-Tamayo, T1
Martínez-Cortés, F1
Moreiras, A1
Ramos-Díaz, JC1
García-Martín, FJ1
Martínez Valverde, A1
Malik, GM1
Lozano, E1
Castillejos, ML1
Abad, L1
Merkle, HP1
Heldenberg, D1
Sevi, R1
Issa, H1
Jamal, M1
Beato, JL1
Segura, JC1
de Tomas, E1
Abu-Ekteish, F1
Kakish, K1
Sachdev, A1
Vohra, R1
Bijarnia, S1
Bastin, R1
Charmot, G1
Frottier, J1
Smith, CC1
Nigmatulin, AZ1
Guliaev, AE1
Gubenko, LV1
Srymbetov, MS1
Sharafutdinova, GI1
Fountain, MW1
Weiss, SJ1
Fountain, AG1
Shen, A1
Lenk, RP1
Chan, J1
Baxter, C1
Wenman, WM1
Hernández-Caselles, T1
Vera, A1
Crespo, F1
Villalaín, J1
Gómez-Fernández, JC1
al-Kasab, S1
al-Fagih, MR1
al-Yousef, S1
Ali Khan, MA1
Ribeiro, PA1
Nazzal, S1
al-Zaibag, M1
Robertson, L1
Farrell, ID1
Hinchliffe, PM1
Novotný, Z1
Moeschlin, S1

Reviews

6 reviews available for gentamicin and Brucellosis

ArticleYear
The perspective of antibiotic therapeutic challenges of brucellosis in the Middle East and North African countries: Current situation and therapeutic management.
    Transboundary and emerging diseases, 2022, Volume: 69, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Chloramphenicol; Ciprofloxacin; Do

2022
Brucellar Vertebral Osteomyelitis: A Case Report and Brief Review of the Literature.
    Connecticut medicine, 2017, Volume: 81, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Brucella; Brucellosis; Doxycycline; Drug Therapy, Combination; Femal

2017
Brucellosis as a rare cause of olecranon bursitis: case-based review.
    Rheumatology international, 2019, Volume: 39, Issue:12

    Topics: Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Bursitis; Doxycycline; Drug Therapy, Combin

2019
Update on childhood brucellosis.
    Recent patents on anti-infective drug discovery, 2013, Volume: 8, Issue:1

    Topics: Adolescent; Agglutination Tests; Anti-Bacterial Agents; Brucellosis; Child; Doxycycline; Drug Therap

2013
Brucellar spondylitis: review of 35 cases and literature survey.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Volume: 29, Issue:6

    Topics: Adolescent; Adult; Aged; Aminoglycosides; Brucella melitensis; Brucellosis; Doxycycline; Drug Therap

1999
Pneumonia as the sole presentation of brucellosis.
    Respiratory medicine, 2001, Volume: 95, Issue:9

    Topics: Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Child, Preschool; Gentamicins; Humans; Male

2001

Trials

5 trials available for gentamicin and Brucellosis

ArticleYear
A randomized double-blinded placebo-controlled clinical trial on protective effects of pentoxifylline on gentamicin nephrotoxicity in infectious patients.
    Clinical and experimental nephrology, 2021, Volume: 25, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Brucellosis; Double-Blind Method; Female; Gentamicins; Humans; Male; M

2021
Comparison of the efficacy of gentamicin for 5 days plus doxycycline for 8 weeks versus streptomycin for 2 weeks plus doxycycline for 45 days in the treatment of human brucellosis: a randomized clinical trial.
    The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Brucellosis; Doxycycline; Drug Therapy, Combination; Female; Gentamici

2010
Doxycycline-rifampin versus doxycycline-rifampin-gentamicin in treatment of human brucellosis.
    Tropical doctor, 2012, Volume: 42, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anti-Bacterial Agents; Brucellosis; Child; Doxy

2012
Efficacy of gentamicin plus doxycycline versus streptomycin plus doxycycline in the treatment of brucellosis in humans.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Apr-15, Volume: 42, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Brucellosis; Doxycycline; Drug Ad

2006
Treatment of human brucellosis with doxycycline and gentamicin.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Brucellosis; Child; Doxycycline; Drug Therapy, Combination

1997

Other Studies

61 other studies available for gentamicin and Brucellosis

ArticleYear
Congenital brucellosis associated with subsequent Klebsiella pneumoniae co-infection in a premature neonate: A rare case report.
    Journal of infection and public health, 2022, Volume: 15, Issue:5

    Topics: Amikacin; Anti-Bacterial Agents; Brucellosis; Ciprofloxacin; Coinfection; Female; Gentamicins; Human

2022
Assessing the Risk of Nephrotoxicity Associated with Aminoglycosides in Brucellosis Patients: A Cross-sectional Study.
    Current drug safety, 2023, Volume: 18, Issue:3

    Topics: Aged; Aminoglycosides; Anti-Bacterial Agents; Brucellosis; Creatinine; Cross-Sectional Studies; Fema

2023
Interaction of gentamicin and gentamicin-AOT with poly-(lactide-co-glycolate) in a drug delivery system - density functional theory calculations and molecular dynamics simulation.
    Biophysical chemistry, 2023, Volume: 294

    Topics: Anti-Bacterial Agents; Brucellosis; Density Functional Theory; Drug Delivery Systems; Gentamicins; G

2023
The canonical Brucella species-host dependency is changing, however, the antibiotic susceptibility profiles remain unchanged.
    Microbial pathogenesis, 2023, Volume: 182

    Topics: Animals; Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Cattle; Cefoperazone; Ciprofloxaci

2023
Acute Thyroiditis Associated with Brucellosis: A Case Report.
    Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki), 2019, Oct-01, Volume: 40, Issue:2

    Topics: Acute Disease; Anti-Bacterial Agents; Arthritis; Brucellosis; Ciprofloxacin; Gentamicins; Humans; Ma

2019
The expression of type II TA system genes following exposure to the sub-inhibitory concentration of gentamicin and acid stress in Brucella spp.
    Microbial pathogenesis, 2020, Volume: 144

    Topics: Acids; Animals; Brucella; Brucella abortus; Brucella melitensis; Brucellosis; DNA, Bacterial; Female

2020
Brucellosis, a forgotten cause of hepatitis in travellers.
    Journal of travel medicine, 2021, 04-14, Volume: 28, Issue:3

    Topics: Anti-Bacterial Agents; Bosnia and Herzegovina; Brucellosis; Cheese; Doxycycline; France; Gentamicins

2021
[Brucellosis in Chile: Description of a series of 13 cases].
    Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia, 2017, Volume: 34, Issue:3

    Topics: Adult; Aged; Brucellosis; Chile; Dairy Products; Doxycycline; Drug Therapy, Combination; Female; Gen

2017
Antimicrobial susceptibility of
    Antimicrobial resistance and infection control, 2017, Volume: 6

    Topics: Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Doxycycline; Drug Resistance, Multiple, Bac

2017
RomA, A Periplasmic Protein Involved in the Synthesis of the Lipopolysaccharide, Tunes Down the Inflammatory Response Triggered by Brucella.
    The Journal of infectious diseases, 2018, 03-28, Volume: 217, Issue:8

    Topics: Animals; Bacterial Proteins; Brucella; Brucellosis; Gentamicins; Inflammation; Lipopolysaccharides;

2018
Brucellosis accompanied by haemophagocytic lymphohistiocytosis and multiple splenic abscesses in a patient with depression.
    BMJ case reports, 2018, Mar-27, Volume: 2018

    Topics: Abscess; Adult; Anti-Bacterial Agents; Antidepressive Agents, Second-Generation; Brucellosis; Citalo

2018
Pigs, pooches and pasteurisation: The changing face of brucellosis in Australia
    Australian journal of general practice, 2018, Volume: 47, Issue:3

    Topics: Animals; Anorexia; Anti-Bacterial Agents; Arthralgia; Australia; Brucella abortus; Brucella canis; B

2018
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2018, 09-17, Volume: 190, Issue:37

    Topics: Aged, 80 and over; Animals; Anti-Bacterial Agents; Brucella; Brucellosis; Canada; Endocarditis; Gent

2018
Acute epididymo-orchitis from
    BMJ case reports, 2019, Jul-10, Volume: 12, Issue:7

    Topics: Acute Disease; Adolescent; Anti-Bacterial Agents; Australia; Brucella melitensis; Brucellosis; Doxyc

2019
In vitro antimicrobial susceptibility of Brucella melitensis isolates from sheep in an area endemic for human brucellosis in Turkey.
    The Journal of veterinary medical science, 2013, Volume: 75, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Ciprofloxacin; DNA Primers; Gentam

2013
Hydrophobic gentamicin-loaded nanoparticles are effective against Brucella melitensis infection in mice.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Cell Line; Drug Carriers; Female;

2013
Immunotherapeutics to prevent the replication of Brucella in a treatment failure mouse model.
    Vaccine, 2014, Feb-12, Volume: 32, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Bacterial Outer Membrane Proteins; Brucella;

2014
Brucella arteritis: clinical manifestations, treatment, and prognosis.
    The Lancet. Infectious diseases, 2014, Volume: 14, Issue:6

    Topics: Abattoirs; Aged; Animals; Anti-Bacterial Agents; Aortic Diseases; Bacteremia; Blood Vessel Prosthesi

2014
In vitro antimicrobial susceptibility testing of human Brucella melitensis isolates from Qatar between 2014 - 2015.
    BMC microbiology, 2015, Jun-16, Volume: 15

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Brucella melitensis; Brucellosis; Doxycycline; Drug Resis

2015
Reduced Susceptibility to Rifampicin and Resistance to Multiple Antimicrobial Agents among Brucella abortus Isolates from Cattle in Brazil.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Bacterial Typing Techniques; Brazil; Brucella abortus; Brucellosis;

2015
A case of acute septic arthritis hip caused by Brucella melitensis in an adolescent child.
    BMJ case reports, 2015, Sep-21, Volume: 2015

    Topics: Acute Disease; Anti-Bacterial Agents; Arthritis, Infectious; Brucella melitensis; Brucellosis; Child

2015
[Imported Bacteremia].
    Klinische Padiatrie, 2016, Volume: 228, Issue:4

    Topics: Administration, Oral; Arteries; Arthralgia; Bacteremia; Brucella melitensis; Brucellosis; Child; Dia

2016
Long-standing, neglected sacroiliitis with remarked sacro-iliac degenerative changes as a result of Brucella spp. infection.
    The spine journal : official journal of the North American Spine Society, 2009, Volume: 9, Issue:3

    Topics: Aged; Anti-Bacterial Agents; Arthritis, Infectious; Brucellosis; Doxycycline; Female; Gentamicins; H

2009
[Sacroilitis and osteomyelitis of the humeral bone du to Brucella melitensis in an adolescent].
    Revue medicale de Liege, 2008, Volume: 63, Issue:12

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Arthritis, Infectious; Brucella melitensis; Bruc

2008
Bang! The smoker with suprapubic pain.
    Lancet (London, England), 2009, Jul-11, Volume: 374, Issue:9684

    Topics: Abdominal Pain; Aneurysm, Infected; Anti-Bacterial Agents; Aortic Aneurysm, Abdominal; Arteriosclero

2009
Index of suspicion.
    Pediatrics in review, 2009, Volume: 30, Issue:9

    Topics: Abscess; Adolescent; Anti-Bacterial Agents; Brucellosis; Cefuroxime; Child; Doxycycline; Female; Gen

2009
Novel bioactive hydrophobic gentamicin carriers for the treatment of intracellular bacterial infections.
    Acta biomaterialia, 2011, Volume: 7, Issue:4

    Topics: Anti-Infective Agents; Brucella melitensis; Brucellosis; Chemical Precipitation; Crystallization; Di

2011
Antimicrobial susceptibility of Brucella melitensis isolates in Peru.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:3

    Topics: Anti-Infective Agents; Azithromycin; Brucella melitensis; Brucellosis; Ciprofloxacin; Doxycycline; G

2011
[Brucellosis in the human].
    Praxis, 2011, Mar-02, Volume: 100, Issue:5

    Topics: Adult; Animals; Anti-Bacterial Agents; Brucellosis; Cheese; Delayed Diagnosis; Doxycycline; Drug The

2011
Unusual presentations of pediatric neurobrucellosis.
    The American journal of tropical medicine and hygiene, 2012, Volume: 86, Issue:2

    Topics: Adolescent; Anti-Bacterial Agents; Brucellosis; Child; Doxycycline; Drug Therapy, Combination; Encep

2012
[Primary brucellar psoas abscess with unexpected serological results].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2012, Volume: 25, Issue:2

    Topics: Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Diagnostic Errors; Doxycycline; Gentamicins

2012
Brucellar joint involvement presented with chest pain.
    The Indian journal of medical research, 2012, Volume: 136, Issue:4

    Topics: Agglutination Tests; Anti-Bacterial Agents; Brucellosis; Doxycycline; Gentamicins; Humans; Male; Mid

2012
[Brucellosis complicated by a psoas muscle abscess].
    Enfermedades infecciosas y microbiologia clinica, 2004, Volume: 22, Issue:3

    Topics: Brucellosis; Doxycycline; Drug Therapy, Combination; Gentamicins; Humans; Lumbar Vertebrae; Male; Mi

2004
Gentamicin-loaded microspheres for reducing the intracellular Brucella abortus load in infected monocytes.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Brucella abortus; Brucellosis; Cell Line; Drug Compounding; Gentamic

2004
Gentamicin-loaded microspheres for treatment of experimental Brucella abortus infection in mice.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 55, Issue:6

    Topics: Animals; Brucella abortus; Brucellosis; Female; Gentamicins; Lactic Acid; Mice; Microspheres; Polygl

2005
Brucellosis: the first case of King Chulalongkorn Memorial Hospital and review of the literature.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2006, Volume: 89, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Doxycycline; Drug Therapy, Combina

2006
Poly(D,L-lactide-coglycolide) particles containing gentamicin: pharmacokinetics and pharmacodynamics in Brucella melitensis-infected mice.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Disease Models, Animal; Drug Carri

2007
Congenital brucellosis: a rare cause of respiratory distress in neonates.
    American journal of perinatology, 2007, Volume: 24, Issue:7

    Topics: Agriculture; Anti-Infective Agents; Brucellosis; Drug Therapy, Combination; Female; Gentamicins; Hum

2007
Hepatic abscess: a rare manifestation of brucellosis in children.
    European journal of pediatrics, 2008, Volume: 167, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Brucella melitensis; Brucellosis; Child, Preschool; Fe

2008
Perspectives for the treatment of brucellosis in the 21st century: the Ioannina recommendations.
    PLoS medicine, 2007, Volume: 4, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Biomedical Research; Brucellosis; Developing Countries; Doxycycline;

2007
Brucella endocarditis--a successfully treated case.
    The Journal of infection, 1980, Volume: 2, Issue:3

    Topics: Adult; Brucellosis; Endocarditis, Bacterial; Gentamicins; Humans; Male; Oxytetracycline

1980
Case report: brucella osteomyelitis--a difficult diagnosis.
    Journal of the Royal Naval Medical Service, 1995,Winter, Volume: 80, Issue:3

    Topics: Anti-Bacterial Agents; Brucellosis; Gentamicins; Humans; Male; Middle Aged; Osteomyelitis

1995
Persistent coccobacillary sepsis in a preterm newborn.
    The Pediatric infectious disease journal, 1993, Volume: 12, Issue:6

    Topics: Bacteremia; Brucella melitensis; Brucellosis; Drug Therapy, Combination; Gentamicins; Humans; Infant

1993
Brucellosis presenting with cough.
    The Pediatric infectious disease journal, 1995, Volume: 14, Issue:8

    Topics: Adolescent; Anti-Bacterial Agents; Antibiotics, Antitubercular; Biopsy; Bone Marrow; Brucella melite

1995
Acute thrombocytopenic purpura in childhood brucellosis.
    Annals of tropical paediatrics, 1995, Volume: 15, Issue:3

    Topics: Acute Disease; Blood Platelets; Bone Marrow; Brucellosis; Child; Child, Preschool; Diagnosis, Differ

1995
Failure of short-term antimicrobial therapy in childhood brucellosis.
    The Pediatric infectious disease journal, 1997, Volume: 16, Issue:3

    Topics: Brucellosis; Child; Child, Preschool; Doxycycline; Drug Administration Schedule; Drug Therapy, Combi

1997
Early clinical response to different therapeutic regimens for human brucellosis.
    The American journal of tropical medicine and hygiene, 1998, Volume: 58, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anti-Bacterial Agen

1998
Gentamicin encapsulation in PLA/PLGA microspheres in view of treating Brucella infections.
    International journal of pharmaceutics, 2000, Feb-25, Volume: 196, Issue:1

    Topics: Biocompatible Materials; Brucellosis; Drug Compounding; Gentamicins; Lactic Acid; Microbial Sensitiv

2000
[Discitis in brucellosis is not responsive to anti-brucella treatment].
    Harefuah, 1998, Volume: 135, Issue:1-2

    Topics: Adolescent; Brucellosis; Cloxacillin; Discitis; Doxycycline; Drug Therapy, Combination; Female; Gent

1998
Brucellosis in children in south Jordan.
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 1999, Volume: 5, Issue:5

    Topics: Adolescent; Anemia; Animals; Anti-Bacterial Agents; Arthralgia; Brucellosis; Child; Child, Preschool

1999
Azithromycin and gentamicin therapy for the treatment of humans with brucellosis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Feb-01, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Brucellosis; Child; Drug Therapy, Combinatio

2001
Acute brucellosis of childhood: a case report with unusual features.
    Indian pediatrics, 2001, Volume: 38, Issue:12

    Topics: Acute Disease; Agglutination Tests; Anti-Bacterial Agents; Anti-Infective Agents; Brucellosis; Child

2001
[Infectious and parasitic diseases: overview of current status in 1979].
    La Revue du praticien, 1979, May-11, Volume: 29, Issue:27

    Topics: Anti-Bacterial Agents; Brucellosis; Cephalosporins; Drug Combinations; France; Gentamicins; Hepatiti

1979
Treatment of human brucellosis.
    Scottish medical journal, 1976, Volume: 21, Issue:3

    Topics: Acute Disease; Anti-Bacterial Agents; Brucellosis; Chronic Disease; Doxycycline; Drug Combinations;

1976
[Antibiotic binding by leukocytes from brucellosis patients].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1990, Volume: 35, Issue:9

    Topics: Adult; Anti-Bacterial Agents; Brucellosis; Erythromycin; Female; Gentamicins; Humans; Leukocytes; Ma

1990
Treatment of Brucella canis and Brucella abortus in vitro and in vivo by stable plurilamellar vesicle-encapsulated aminoglycosides.
    The Journal of infectious diseases, 1985, Volume: 152, Issue:3

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Brucella; Brucella abortus; Brucellosis; Cells, Cul

1985
Brucellosis in an inuit child, probably related to caribou meat consumption.
    Scandinavian journal of infectious diseases, 1989, Volume: 21, Issue:3

    Topics: Animals; Brucellosis; Canada; Child; Drug Therapy, Combination; Food Contamination; Gentamicins; Hum

1989
Treatment of Brucella melitensis infection in mice by use of liposome-encapsulated gentamicin.
    American journal of veterinary research, 1989, Volume: 50, Issue:9

    Topics: Amines; Animals; Brucella; Brucellosis; Cholesterol; Drug Carriers; Gentamicins; Liposomes; Macropha

1989
Brucella infective endocarditis. Successful combined medical and surgical therapy.
    The Journal of thoracic and cardiovascular surgery, 1988, Volume: 95, Issue:5

    Topics: Adult; Aortic Valve; Brucellosis; Combined Modality Therapy; Drug Combinations; Echocardiography; En

1988
The sensitivity of Brucella abortus to chemotherapeutic agents.
    Journal of medical microbiology, 1973, Volume: 6, Issue:4

    Topics: Ampicillin; Brucella abortus; Brucellosis; Carbenicillin; Drug Synergism; Gentamicins; Humans; Kanam

1973
[Clinical experience with the broadspectrum antibiotic gentamycin (1969-1970)].
    Schweizerische medizinische Wochenschrift, 1972, Jan-08, Volume: 102, Issue:1

    Topics: Adult; Bronchitis; Bronchopneumonia; Brucellosis; Gentamicins; Humans; Injections, Intramuscular; Ki

1972