Page last updated: 2024-10-27

gentamicin and Breast Cancer

gentamicin has been researched along with Breast Cancer in 16 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to investigate whether gentamicin-collagen (GC) sponges can lower the incidence of seroma and surgical site infections following breast cancer surgery."7.88Can Gentamicin-collagen Sponges Prevent Seroma Formation Following Mastectomy? ( de Wilt, JHW; Polat, F; Strobbe, LJA; Ten Wolde, B; van den Wildenberg, FJH, 2018)
" In brief, we investigated this perpetuation of injury on untreated bystander MCF-7 breast cancer cells which were coplated with 5-fluorouracil (5-FU)-treated MDA-MB-231 breast cancer cells."7.74Bystander killing of breast cancer MCF-7 cells by MDA-MB-231 cells exposed to 5-fluorouracil is mediated via Fas. ( Bhat, MK; Chhipa, RR, 2007)
" In this study, we tested the effect of gentamicin in culture media on human mammary epithelial MCF-12A and breast cancer MCF-7 and MDA-MB-231 cell lines by real time PCR, immunofluorescent microscopy, lactate assay, DNA damage assay."3.91The adverse effect of gentamicin on cell metabolism in three cultured mammary cell lines: "Are cell culture data skewed?" ( Elliott, RL; Jiang, XP, 2019)
"The aim of this study was to investigate whether gentamicin-collagen (GC) sponges can lower the incidence of seroma and surgical site infections following breast cancer surgery."3.88Can Gentamicin-collagen Sponges Prevent Seroma Formation Following Mastectomy? ( de Wilt, JHW; Polat, F; Strobbe, LJA; Ten Wolde, B; van den Wildenberg, FJH, 2018)
" In brief, we investigated this perpetuation of injury on untreated bystander MCF-7 breast cancer cells which were coplated with 5-fluorouracil (5-FU)-treated MDA-MB-231 breast cancer cells."3.74Bystander killing of breast cancer MCF-7 cells by MDA-MB-231 cells exposed to 5-fluorouracil is mediated via Fas. ( Bhat, MK; Chhipa, RR, 2007)
" Examples will be presented of the identification of surrogate markers for hepatocellular carcinoma, breast cancer, from cerebrospinal fluid in humans and gentamicin toxicity in the rat."3.71Proteomic profiling from human samples: the body fluid alternative. ( Kennedy, S, 2001)
"Inclusion criteria were a diagnosis of breast neoplasms and plans to undergo an elective axillary lymph node dissection due to axillary metastasis."2.78Effect of gentamicin lavage of the axillary surgical bed after lymph node dissection on drainage discharge volume. ( Arroyo, A; Calero, P; Calpena, R; Cansado, P; Diez, M; Gomez, MA; Llavero, C; Perez-Soler, M; Ruiz-Tovar, J; Zubiaga, L, 2013)
"In this study, human breast cancer cells transiently and stably expressing HSP27-EGFP chimera were utilized to observe the intracellular localization of HSP27."1.33Expression and distribution of HSP27 in response to G418 in different human breast cancer cell lines. ( Guo, N; Hu, M; Qian, L; Shen, B; Shi, M; Xia, Q; Yu, M; Zhang, Z, 2006)
"Because chemotherapeutic protocols for breast cancer are commonly limited by bone marrow toxicity, transduction of genes into pleuripotent stem cells may allow the generation and maintenance of immune responses in the presence of lymphocytotoxic agents."1.29Retroviral gene transduction of circulating progenitor cells in patients with metastatic breast cancer. ( Boyle, TJ; Coles, RE; Kurtzberg, J; Lyerly, HK; Peters, WP; Stewart, A, 1993)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's4 (25.00)18.2507
2000's4 (25.00)29.6817
2010's4 (25.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Tirrell, AR1
Bekeny, JC1
Tefera, EA1
Song, DH1
Fan, KL1
Ten Wolde, B1
van den Wildenberg, FJH1
Polat, F1
de Wilt, JHW1
Strobbe, LJA1
Elliott, RL1
Jiang, XP1
Ruiz-Tovar, J1
Cansado, P1
Perez-Soler, M1
Gomez, MA1
Llavero, C1
Calero, P1
Zubiaga, L1
Diez, M1
Arroyo, A1
Calpena, R1
Hidalgo-García, Y1
Gonzálvo, P1
Mallo-García, S1
Fernández-Sánchez, C1
Hwang, YS1
Chen, YF1
Lai, CC1
Chen, HS1
Hsiao, CH1
Qian, L1
Zhang, Z1
Shi, M1
Yu, M1
Hu, M1
Xia, Q1
Shen, B1
Guo, N1
Chhipa, RR1
Bhat, MK1
Coles, RE1
Boyle, TJ1
Kurtzberg, J1
Stewart, A1
Peters, WP1
Lyerly, HK1
Mairesse, N1
Horman, S1
Mosselmans, R1
Galand, P1
Campain, JA1
Terrell, KL1
Tomczak, JA1
Shpall, EJ1
Hami, LS1
Harrison, GS1
Hausner, P1
Venzon, DJ1
Grogan, L1
Kirsch, IR1
Kennedy, S1
Bondy, PK1
Rosenoff, SH1
Wolf, ML1
Chabner, BA1
Portnoy, J1
Menielson, J1
Dechene, JP1
Shragovitch, I1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT01700504]Phase 340 participants (Actual)Interventional2011-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for gentamicin and Breast Cancer

ArticleYear
Clear Cell Acanthoma of the Areola and Nipple.
    Actas dermo-sifiliograficas, 2016, Volume: 107, Issue:9

    Topics: Acanthoma; Aged; Betamethasone; Breast Neoplasms; Female; Gentamicins; Humans; Nipples; Skin Neoplas

2016

Trials

1 trial available for gentamicin and Breast Cancer

ArticleYear
Effect of gentamicin lavage of the axillary surgical bed after lymph node dissection on drainage discharge volume.
    Breast (Edinburgh, Scotland), 2013, Volume: 22, Issue:5

    Topics: Adult; Aged; Anti-Bacterial Agents; Axilla; Breast Neoplasms; Catheters; Drainage; Exudates and Tran

2013

Other Studies

14 other studies available for gentamicin and Breast Cancer

ArticleYear
Bacitracin for Injection Recall: Impact on Immediate Breast Implant Surgical Outcomes.
    The breast journal, 2022, Volume: 2022

    Topics: Anti-Bacterial Agents; Bacitracin; Breast Implants; Breast Neoplasms; Cefazolin; Female; Gentamicins

2022
Can Gentamicin-collagen Sponges Prevent Seroma Formation Following Mastectomy?
    Clinical breast cancer, 2018, Volume: 18, Issue:5

    Topics: Aged; Axilla; Breast Neoplasms; Collagen; Drainage; Female; Gentamicins; Humans; Lymph Node Excision

2018
The adverse effect of gentamicin on cell metabolism in three cultured mammary cell lines: "Are cell culture data skewed?"
    PloS one, 2019, Volume: 14, Issue:4

    Topics: Anti-Bacterial Agents; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Culture Media

2019
Infectious scleritis after use of immunomodulators.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2002, Volume: 120, Issue:8

    Topics: Adjuvants, Immunologic; Anti-Bacterial Agents; Breast Neoplasms; Cyclophosphamide; Epirubicin; Eye I

2002
Expression and distribution of HSP27 in response to G418 in different human breast cancer cell lines.
    Histochemistry and cell biology, 2006, Volume: 126, Issue:5

    Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Female; Gentamicins; Green Fluo

2006
Bystander killing of breast cancer MCF-7 cells by MDA-MB-231 cells exposed to 5-fluorouracil is mediated via Fas.
    Journal of cellular biochemistry, 2007, May-01, Volume: 101, Issue:1

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Breast Neoplasms; Bystander Effect; Caspase 8; Cell Line

2007
Retroviral gene transduction of circulating progenitor cells in patients with metastatic breast cancer.
    Surgical oncology, 1993, Volume: 2, Issue:1

    Topics: Base Sequence; Breast Neoplasms; DNA; Drug Resistance; Female; Gene Expression Regulation, Viral; Ge

1993
Antisense inhibition of the 27 kDa heat shock protein production affects growth rate and cytoskeletal organization in MCF-7 cells.
    Cell biology international, 1996, Volume: 20, Issue:3

    Topics: Actins; Antibody Specificity; Antisense Elements (Genetics); Base Sequence; Blotting, Western; Breas

1996
Comparison of retroviral-mediated gene transfer into cultured human CD34+ hematopoietic progenitor cells derived from peripheral blood, bone marrow, and fetal umbilical cord blood.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 1997, Volume: 3, Issue:5

    Topics: Animals; Blood Cells; Bone Marrow Cells; Breast Neoplasms; Cells, Cultured; Centrifugation; Colony-F

1997
The "comparative growth assay": examining the interplay of anti-cancer agents with cells carrying single gene alterations.
    Neoplasia (New York, N.Y.), 1999, Volume: 1, Issue:4

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member

1999
Proteomic profiling from human samples: the body fluid alternative.
    Toxicology letters, 2001, Mar-31, Volume: 120, Issue:1-3

    Topics: Body Fluids; Breast Neoplasms; Carcinoma, Hepatocellular; Gentamicins; Humans; Liver Neoplasms; Prot

2001
Some 'pseudo' and some true endocrine syndromes in cancer.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:1

    Topics: Adrenocorticotropic Hormone; Alkalosis; Bicarbonates; Breast Neoplasms; Calcium; Carcinoma, Bronchog

1974
Pseudomonas blepharoconjunctivitis: a complication of combination chemotherapy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1974, Volume: 91, Issue:6

    Topics: Antineoplastic Agents; Bacitracin; Blepharitis; Bone Marrow; Breast Neoplasms; Carbenicillin; Cephal

1974
An outbreak of streptococcal wound sepsis: contamination of the wound during operation.
    Canadian Anaesthetists' Society journal, 1974, Volume: 21, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Ampicillin; Breast Neoplasms; Carcinoma; Cross Infection; Cysts; Diseas

1974