gentamicin has been researched along with Appendicitis in 68 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Appendicitis: Acute inflammation of the APPENDIX. Acute appendicitis is classified as simple, gangrenous, or perforated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a 3-year study, 103 children with acute non-perforated appendicitis who underwent appendicectomy were randomized for either a single preoperative dose of gentamicin and metronidazole or three doses of gentamicin and metronidazole given before and after the operation." | 10.17 | Antibiotic prophylaxis in acute non-perforated appendicitis in children: single dose of metronidazole and gentamicin. ( Saing, H; Tam, PK; Tsang, TM, 1992) |
| "The primary objective of this study was to compare triple therapy with ertapenem treatments in pediatric patients with perforated appendicitis, especially in terms of postoperative infectious complications." | 9.19 | Ertapenem versus standard triple antibiotic therapy for the treatment of perforated appendicitis in pediatric patients: a prospective randomized trial. ( Bayraktar, B; Celebi, S; Dalgic, N; Dokucu, AI; Kafadar, I; Kara, O; Karadag, CA; Pelit, S; Sancar, M, 2014) |
| " Historically, a 3-drug regimen consisting of ampicillin, gentamicin, and clindamycin (AGC) has been used postoperatively for perforated appendicitis." | 9.13 | Single daily dosing ceftriaxone and metronidazole vs standard triple antibiotic regimen for perforated appendicitis in children: a prospective randomized trial. ( Andrews, WS; Holcomb, GW; Murphy, JP; Ostlie, DJ; Sharp, RJ; Sharp, SW; Snyder, CL; Spilde, TL; St Peter, SD; Tsao, K, 2008) |
| "The purpose of this study was to determine the influence of weight with gentamicin assay error on the Bayesian and nonlinear least squares regression analysis in 12 Korean appendicitis patients." | 9.11 | The influence of weight with assay error on gentamicin pharmacokinetics using the Bayesian and nonlinear least square regression analysis in appendicitis patients. ( Burm, JP, 2005) |
| "This prospective, randomized, double-blind study compares the efficacy, safety and cost-effectiveness of ampicillin, gentamicin and clindamycin (AGC) or cefotaxime and clindamycin (CC) for the treatment of children with complicated appendicitis." | 9.07 | A randomized clinical trial of ampicillin, gentamicin and clindamycin versus cefotaxime and clindamycin in children with ruptured appendicitis. ( Golladay, ES; Kaplan, S; King, DR; Mason, EO; Mollitt, DL; Pokorny, W; Schropp, KP; Wise, WE, 1991) |
| "A randomized, double-blinded, controlled clinical study of 84 patients with surgically treated gangrenous or perforated appendicitis was done to compare the efficacy of the combination of aztreonam, the first monobactam antibiotic, with gentamicin when either was combined with clindamycin." | 9.06 | Surgically treated gangrenous or perforated appendicitis. A comparison of aztreonam and clindamycin versus gentamicin and clindamycin. ( Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1987) |
| "A study on 42 surgical patients was carried out to find out whether cefuroxime may be substituted for gentamicin in combination with metronidazole in the treatment of peritonitis secondary to perforation of appendix." | 9.05 | Comparison of cefuroxime and gentamicin in combination with metronidazole in the treatment of peritonitis due to perforation of the appendix. ( Arvilommi, H; Saario, I; Silvola, H, 1983) |
| "The purpose of this study was to determine the influence of weight with gentamicin assay error on the Bayesian and nonlinear least squares regression analysis in 12 Korean appendicitis patients." | 7.73 | The influence of assay error weight on gentamicin pharmacokinetics using the Bayesian and nonlinear least square regression analysis in appendicitis patients. ( Burm, JP, 2005) |
| "A matched case-control study of the efficacy of gentamicin dosage adjustment through the use of pharmacokinetic analysis of serum drug concentrations in patients treated by appendectomy for perforated or gangrenous appendicitis was performed." | 7.67 | Matched case-control study of adjusted versus nonadjusted gentamicin dosing in perforated and gangrenous appendicitis. ( Appleman, MD; Berne, TV; Cheetham, TC; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1986) |
| "Patients with gangrenous or perforated appendicitis were treated with cefoxitin or a combination of clindamycin and gentamicin for a minimum of five post-operative days." | 7.67 | Antimicrobial management of surgically treated gangrenous or perforated appendicitis: comparison of cefoxitin and clindamycin-gentamicin. ( Levine, BA; Sirinek, KR, 1987) |
| " Ticarcillin and clavulanic acid is a safe and effective alternative to gentamicin and clindamycin in the treatment of secondary bacterial peritonitis and offers advantages in dosing simplicity and freedom from ototoxic and nephrotoxic effects." | 6.67 | A randomized trial of ticarcillin and clavulanate versus gentamicin and clindamycin in patients with complicated appendicitis. ( Levine, BA; Sirinek, KR, 1991) |
| "In a 3-year study, 103 children with acute non-perforated appendicitis who underwent appendicectomy were randomized for either a single preoperative dose of gentamicin and metronidazole or three doses of gentamicin and metronidazole given before and after the operation." | 6.17 | Antibiotic prophylaxis in acute non-perforated appendicitis in children: single dose of metronidazole and gentamicin. ( Saing, H; Tam, PK; Tsang, TM, 1992) |
| " It emerged from the study that if Gentamicin is to be given intra-peritoneally, the dosage should be higher than that recommended for the intramuscular or intravenous route and that levels should be monitored because of interpatient variation in response." | 5.26 | Intraperitoneal gentamicin in appendiceal peritonitis in children: a pharmacokinetic study. ( Constantinides, C; Daikos, GC; Giamarellou, H; Pappis, C; Petrikkos, G, 1981) |
| "The primary objective of this study was to compare triple therapy with ertapenem treatments in pediatric patients with perforated appendicitis, especially in terms of postoperative infectious complications." | 5.19 | Ertapenem versus standard triple antibiotic therapy for the treatment of perforated appendicitis in pediatric patients: a prospective randomized trial. ( Bayraktar, B; Celebi, S; Dalgic, N; Dokucu, AI; Kafadar, I; Kara, O; Karadag, CA; Pelit, S; Sancar, M, 2014) |
| " Historically, a 3-drug regimen consisting of ampicillin, gentamicin, and clindamycin (AGC) has been used postoperatively for perforated appendicitis." | 5.13 | Single daily dosing ceftriaxone and metronidazole vs standard triple antibiotic regimen for perforated appendicitis in children: a prospective randomized trial. ( Andrews, WS; Holcomb, GW; Murphy, JP; Ostlie, DJ; Sharp, RJ; Sharp, SW; Snyder, CL; Spilde, TL; St Peter, SD; Tsao, K, 2008) |
| "The purpose of this study was to determine the influence of weight with gentamicin assay error on the Bayesian and nonlinear least squares regression analysis in 12 Korean appendicitis patients." | 5.11 | The influence of weight with assay error on gentamicin pharmacokinetics using the Bayesian and nonlinear least square regression analysis in appendicitis patients. ( Burm, JP, 2005) |
| "A prospective randomized study was undertaken to compare the use of the combination of gentamicin and clindamycin with single agent, cefoxitin, in the treatment of perforated appendicitis in the pediatric patient." | 5.07 | One-drug versus two-drug antibiotic therapy in pediatric perforated appendicitis: a prospective randomized study. ( Federer, L; Hall, JR; Loeff, DS; Meller, JL; Reyes, HM, 1991) |
| "This prospective, randomized, double-blind study compares the efficacy, safety and cost-effectiveness of ampicillin, gentamicin and clindamycin (AGC) or cefotaxime and clindamycin (CC) for the treatment of children with complicated appendicitis." | 5.07 | A randomized clinical trial of ampicillin, gentamicin and clindamycin versus cefotaxime and clindamycin in children with ruptured appendicitis. ( Golladay, ES; Kaplan, S; King, DR; Mason, EO; Mollitt, DL; Pokorny, W; Schropp, KP; Wise, WE, 1991) |
| "A randomized, double-blinded, controlled clinical study of 84 patients with surgically treated gangrenous or perforated appendicitis was done to compare the efficacy of the combination of aztreonam, the first monobactam antibiotic, with gentamicin when either was combined with clindamycin." | 5.06 | Surgically treated gangrenous or perforated appendicitis. A comparison of aztreonam and clindamycin versus gentamicin and clindamycin. ( Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1987) |
| "Three hundred and seven patients with appendicitis were randomized to receive cefoxitin or gentamicin and metronidazole." | 5.06 | Cefoxitin versus gentamicin and metronidazole in prevention of post-appendicectomy sepsis: a randomized, prospective trial. ( Chu, KW; Fan, ST; Lau, WY; Wong, KK; Yeung, C; Yip, WC; Yiu, TF, 1986) |
| "A study on 42 surgical patients was carried out to find out whether cefuroxime may be substituted for gentamicin in combination with metronidazole in the treatment of peritonitis secondary to perforation of appendix." | 5.05 | Comparison of cefuroxime and gentamicin in combination with metronidazole in the treatment of peritonitis due to perforation of the appendix. ( Arvilommi, H; Saario, I; Silvola, H, 1983) |
| "A prospective, randomized, double-blind clinical trial was undertaken comparing gentamicin, ampicillin, and clindamycin (GAC) to gentamicin, ampicillin, and placebo (GAP) in children with complicated appendicitis." | 5.05 | Antibiotic management of complicated appendicitis. ( Birken, GA; Boles, ET; Browne, AF; Hilty, MD; Kerzner, B; King, DR, 1983) |
| "Single doses of clindamycin hydrochloride and gentamicin sulfate given preoperatively, combined with intraoperative topical application of povidone-iodine were given to patients with perforated or gangrenous appendicitis." | 5.05 | Combined preoperative antibiotic therapy and intraoperative topical povidone-iodine. Reduction of wound sepsis following emergency appendectomy. ( Holl-Allen, RT; Sherlock, DJ; Ward, A, 1984) |
| "60 consecutive children operated for perforated appendicitis were treated randomly with either penicillin and streptomycin or with clindamycin and gentamycin." | 5.05 | Perforated appendix and antibiotics. ( Kekomäki, M; Louhimo, I, 1981) |
| " Historically, a triple-antibiotic therapy consisted of ampicillin, gentamicin, and clindamycin has been used postoperatively for perforated appendicitis." | 3.88 | Dual versus Triple Antibiotics Regimen in Children with Perforated Acute Appendicitis. ( Baazov, A; Dreznik, Y; Feigin, E; Freud, E; Kravarusic, D; Levy, I; Livni, G; Samuk, I, 2018) |
| "The purpose of this study was to determine the influence of weight with gentamicin assay error on the Bayesian and nonlinear least squares regression analysis in 12 Korean appendicitis patients." | 3.73 | The influence of assay error weight on gentamicin pharmacokinetics using the Bayesian and nonlinear least square regression analysis in appendicitis patients. ( Burm, JP, 2005) |
| "Ticarcillin/clavulanate plus gentamicin was clinically more effective than ampicillin, gentamicin, and clindamycin combination therapy in the management of perforated appendicitis in our pediatric population." | 3.70 | Comparison of two antibiotic regimens in the treatment of perforated appendicitis in pediatric patients. ( Buckner, D; Gomez-Marin, O; Oiticica, C; Rodriguez, JC; Schoenike, S; Thompson, WR, 2000) |
| "Gentamicin concentrations in appendix tissue, serum, and peritoneal fluid were obtained in suspected cases of gangrenous or perforated appendicitis." | 3.67 | Gentamicin penetration into diseased appendix tissue. ( Berne, TV; Chandrasoma, P; Chenella, FC; Chung, H; Cohen, JL; Gill, MA; Heseltine, PN; Hisayasu, GH; Warnecke, GM; Yellin, AE, 1984) |
| "Patients with gangrenous or perforated appendicitis were treated with cefoxitin or a combination of clindamycin and gentamicin for a minimum of five post-operative days." | 3.67 | Antimicrobial management of surgically treated gangrenous or perforated appendicitis: comparison of cefoxitin and clindamycin-gentamicin. ( Levine, BA; Sirinek, KR, 1987) |
| "A matched case-control study of the efficacy of gentamicin dosage adjustment through the use of pharmacokinetic analysis of serum drug concentrations in patients treated by appendectomy for perforated or gangrenous appendicitis was performed." | 3.67 | Matched case-control study of adjusted versus nonadjusted gentamicin dosing in perforated and gangrenous appendicitis. ( Appleman, MD; Berne, TV; Cheetham, TC; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1986) |
| "The relationships between resistant pathogens, serum levels of gentamicin, and the outcomes of gangrenous or perforated appendicitis were analyzed in 147 patients." | 3.66 | Perforated and gangrenous appendicitis: an analysis of antibiotic failures. ( Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Kern, JW; Yellin, AE, 1983) |
| " Children treated with ampicillin, gentamicin, and clindamycin had markedly fewer wound infections and abscesses and were able to tolerate a diet and go home sooner than those receiving ampicillin and/or gentamicin." | 3.66 | Rational use of antibiotics for perforated appendicitis in childhood. ( Buck, JR; David, IB; Filler, RM, 1982) |
| " None of the patients suffered from an adverse event or a recurrent appendicitis." | 2.80 | Initial antibiotic treatment for acute simple appendicitis in children is safe: Short-term results from a multicenter, prospective cohort study. ( Cense, HA; Gorter, RR; Heij, HA; In 't Hof, KH; Kneepkens, CM; Offringa, M; van der Lee, JH; Wijnen, MH, 2015) |
| "Surgical wound infections were significantly reduced by the collagen-gentamicin implant." | 2.69 | Effectiveness of collagen-gentamicin implant for treatment of "dirty" abdominal wounds. ( Delgado, FJ; Guerrero, TS; Guzmán Valdivia Gomez, G; Lluck, MC, 1999) |
| "Cefepime is a new extended-spectrum cephalosporin with gram-positive and gram-negative coverage including Staphylococcus aureus and Pseudomonas aeruginosa." | 2.67 | Analysis of cefepime tissue penetration into human appendix. ( Appleman, MD; Berne, TV; Chin, A; Gill, MA; Heseltine, PN; Knupp, CA; Okamoto, MP; Sclar, DA; Yellin, AE, 1991) |
| " Ticarcillin and clavulanic acid is a safe and effective alternative to gentamicin and clindamycin in the treatment of secondary bacterial peritonitis and offers advantages in dosing simplicity and freedom from ototoxic and nephrotoxic effects." | 2.67 | A randomized trial of ticarcillin and clavulanate versus gentamicin and clindamycin in patients with complicated appendicitis. ( Levine, BA; Sirinek, KR, 1991) |
| "Metronidazole (M) has potent bactericidal activity against anaerobic bacteria." | 2.65 | Prospective, randomized comparison of metronidazole and clindamycin, each with gentamicin, for the treatment of serious intra-abdominal infection. ( , 1983) |
| "Cumulative incidence of surgical site infection was 2." | 1.51 | Adequacy of antibiotic prophylaxis protocol in appendectomies in children. ( Durán-Poveda, M; García-Cruces, J; Gil-Yonte, P; Rodríguez-Caravaca, G; Rodríguez-Villar, D; Román-Montero, JS, 2019) |
| " The optimized population model allowed us to simulate drug serum levels at 8 and 12h, as well as the area under the curve of gentamicin and its variability in patients with high distribution volumes when dosage regimens based on a single daily dose administration are implemented." | 1.30 | Influence of diagnostic and treatment factors in the population pharmacokinetics of gentamicin. ( Aguado, JM; Antón, J; González, P; Lanao, JM; Romano, S; Tejada, P, 1998) |
| " It emerged from the study that if Gentamicin is to be given intra-peritoneally, the dosage should be higher than that recommended for the intramuscular or intravenous route and that levels should be monitored because of interpatient variation in response." | 1.26 | Intraperitoneal gentamicin in appendiceal peritonitis in children: a pharmacokinetic study. ( Constantinides, C; Daikos, GC; Giamarellou, H; Pappis, C; Petrikkos, G, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (41.18) | 18.7374 |
| 1990's | 20 (29.41) | 18.2507 |
| 2000's | 12 (17.65) | 29.6817 |
| 2010's | 7 (10.29) | 24.3611 |
| 2020's | 1 (1.47) | 2.80 |
| Authors | Studies |
|---|---|
| Emile, SH | 1 |
| Elfallal, AH | 1 |
| Abdel-Razik, MA | 1 |
| El-Said, M | 1 |
| Elshobaky, A | 1 |
| Dreznik, Y | 1 |
| Feigin, E | 1 |
| Samuk, I | 1 |
| Kravarusic, D | 1 |
| Baazov, A | 1 |
| Levy, I | 1 |
| Livni, G | 1 |
| Freud, E | 1 |
| Taleb, M | 1 |
| Nardi, N | 1 |
| Arnaud, A | 1 |
| Costet, N | 1 |
| Donnio, PY | 1 |
| Engrand, C | 1 |
| Habonimana, E | 1 |
| Wodey, E | 1 |
| Tattevin, P | 1 |
| Durán-Poveda, M | 1 |
| Gil-Yonte, P | 1 |
| Rodríguez-Villar, D | 1 |
| García-Cruces, J | 1 |
| Rodríguez-Caravaca, G | 1 |
| Román-Montero, JS | 1 |
| Yefet, E | 1 |
| Romano, S | 2 |
| Chazan, B | 1 |
| Nachum, Z | 1 |
| Dalgic, N | 1 |
| Karadag, CA | 1 |
| Bayraktar, B | 1 |
| Sancar, M | 1 |
| Kara, O | 1 |
| Pelit, S | 1 |
| Celebi, S | 1 |
| Kafadar, I | 1 |
| Dokucu, AI | 1 |
| Obinwa, O | 1 |
| Casidy, M | 1 |
| Flynn, J | 1 |
| Gorter, RR | 1 |
| van der Lee, JH | 1 |
| Cense, HA | 1 |
| Kneepkens, CM | 1 |
| Wijnen, MH | 1 |
| In 't Hof, KH | 1 |
| Offringa, M | 1 |
| Heij, HA | 1 |
| St Peter, SD | 1 |
| Tsao, K | 1 |
| Spilde, TL | 1 |
| Holcomb, GW | 1 |
| Sharp, SW | 1 |
| Murphy, JP | 1 |
| Snyder, CL | 1 |
| Sharp, RJ | 1 |
| Andrews, WS | 1 |
| Ostlie, DJ | 1 |
| Picó, RB | 1 |
| Jiménez, LA | 1 |
| Sánchez, MC | 1 |
| Castelló, CH | 1 |
| Bilbao, AM | 1 |
| Arias, MP | 1 |
| Solera, LS | 1 |
| Ramirez, RV | 1 |
| Velez, MC | 1 |
| Athale, UH | 1 |
| Loe, W | 1 |
| Warrier, RP | 1 |
| Emil, S | 1 |
| Laberge, JM | 1 |
| Mikhail, P | 1 |
| Baican, L | 1 |
| Flageole, H | 1 |
| Nguyen, L | 1 |
| Shaw, K | 1 |
| Dzhumabaev, ES | 1 |
| Akhliddinov, OA | 1 |
| Nadler, EP | 1 |
| Reblock, KK | 1 |
| Ford, HR | 1 |
| Gaines, BA | 1 |
| Burm, JP | 2 |
| Falagas, ME | 1 |
| Siempos, II | 1 |
| Tsakoumis, I | 1 |
| Berne, TV | 11 |
| Yellin, AW | 1 |
| Appleman, MD | 10 |
| Heseltine, PN | 11 |
| Yellin, AE | 10 |
| Gill, MA | 11 |
| Chenella, FC | 7 |
| Kern, JW | 1 |
| Flannigan, GM | 1 |
| Clifford, RP | 1 |
| Carver, RA | 1 |
| Yule, AG | 1 |
| Madden, NP | 1 |
| Saario, I | 1 |
| Arvilommi, H | 1 |
| Silvola, H | 1 |
| King, DR | 2 |
| Browne, AF | 1 |
| Birken, GA | 1 |
| Hilty, MD | 1 |
| Kerzner, B | 1 |
| Boles, ET | 1 |
| Sherlock, DJ | 1 |
| Ward, A | 1 |
| Holl-Allen, RT | 1 |
| Gaffney, PR | 1 |
| Cohen, JL | 1 |
| Hisayasu, GH | 1 |
| Chandrasoma, P | 1 |
| Warnecke, GM | 1 |
| Chung, H | 1 |
| Abdel-Lah, BA | 1 |
| Fernández Alvarez, D | 1 |
| Lozano Sánchez, F | 1 |
| Alvarez Aparicio, E | 1 |
| Gómez Alonso, A | 1 |
| Salazar A-Villalobos, V | 1 |
| David, IB | 1 |
| Buck, JR | 1 |
| Filler, RM | 1 |
| Kekomäki, M | 1 |
| Louhimo, I | 1 |
| Constantinides, C | 1 |
| Pappis, C | 1 |
| Giamarellou, H | 1 |
| Petrikkos, G | 1 |
| Daikos, GC | 1 |
| Olesen, A | 1 |
| Jørgensen, F | 1 |
| Bilde, T | 1 |
| Clausen, E | 1 |
| Laursen, H | 1 |
| Tovar, JA | 1 |
| Gahukamble, DB | 1 |
| Khamage, AS | 1 |
| Gahukamble, LD | 1 |
| Shevkhuzhev, ZA | 1 |
| Khanamatov, MKh | 1 |
| Komarov, NV | 3 |
| Badía, JM | 1 |
| Martínez-Ródenas, F | 1 |
| Oms, LM | 1 |
| Valverde, J | 1 |
| Franch, G | 1 |
| Rosales, A | 1 |
| Serrano, R | 1 |
| Sitges-Serra, A | 1 |
| Polk, HC | 1 |
| Fink, MP | 1 |
| Laverdiere, M | 1 |
| Wilson, SE | 1 |
| Garber, GE | 1 |
| Barie, PS | 1 |
| Hebert, JC | 1 |
| Cheadle, WG | 1 |
| Gill, M | 1 |
| Chin, A | 3 |
| Baker, FJ | 1 |
| Kanashkin, OV | 2 |
| Bagrov, NA | 2 |
| Maslagin, AS | 2 |
| Levy, Y | 1 |
| Berger, SA | 1 |
| Gorea, A | 1 |
| Shnaker, A | 1 |
| Orda, R | 1 |
| Landau, D | 1 |
| Kher, KK | 1 |
| González, P | 1 |
| Tejada, P | 1 |
| Antón, J | 1 |
| Aguado, JM | 1 |
| Lanao, JM | 1 |
| Guzmán Valdivia Gomez, G | 1 |
| Guerrero, TS | 1 |
| Lluck, MC | 1 |
| Delgado, FJ | 1 |
| Schutze, GE | 1 |
| Lowry, JA | 1 |
| Kearns, GL | 1 |
| Rodriguez, JC | 1 |
| Buckner, D | 1 |
| Schoenike, S | 1 |
| Gomez-Marin, O | 1 |
| Oiticica, C | 1 |
| Thompson, WR | 1 |
| Rice, HE | 1 |
| Brown, RL | 1 |
| Gollin, G | 1 |
| Caty, MG | 1 |
| Gilbert, J | 1 |
| Skinner, MA | 1 |
| Glick, PL | 1 |
| Azizkhan, RG | 1 |
| Lari, J | 1 |
| Kirk, D | 1 |
| Howden, R | 1 |
| Berlatzky, Y | 1 |
| Rubin, SZ | 1 |
| Michel, J | 1 |
| Sacks, T | 1 |
| Schiller, M | 1 |
| Stone, HH | 1 |
| Tsang, TM | 1 |
| Tam, PK | 1 |
| Saing, H | 1 |
| Okamoto, MP | 2 |
| Knupp, CA | 1 |
| Sclar, DA | 2 |
| Nakahiro, RK | 1 |
| Chae, JS | 1 |
| Schropp, KP | 1 |
| Kaplan, S | 1 |
| Golladay, ES | 1 |
| Pokorny, W | 1 |
| Mollitt, DL | 1 |
| Wise, WE | 1 |
| Mason, EO | 1 |
| Meller, JL | 1 |
| Reyes, HM | 1 |
| Loeff, DS | 1 |
| Federer, L | 1 |
| Hall, JR | 1 |
| Sirinek, KR | 2 |
| Levine, BA | 2 |
| Topuzov, VS | 1 |
| Tsyganenko, AIa | 1 |
| Kalinichenko, NF | 1 |
| Vasil'chenko, VN | 1 |
| Kovalenko, NI | 1 |
| Davidenko, VB | 1 |
| Gabysheva, LS | 1 |
| Liapunov, NA | 1 |
| Starobinets, ZG | 1 |
| Osolodchenko, TP | 1 |
| Riggio, CE | 1 |
| Andåker, L | 1 |
| Höjer, H | 1 |
| Kihlström, E | 1 |
| Lindhagen, J | 1 |
| Leedom, JM | 1 |
| Hurst, AK | 1 |
| Iseri, KT | 1 |
| Noguchi, JK | 1 |
| Gilman, TM | 1 |
| Jelliffe, RW | 1 |
| Lau, WY | 1 |
| Fan, ST | 1 |
| Chu, KW | 1 |
| Yip, WC | 1 |
| Yiu, TF | 1 |
| Yeung, C | 1 |
| Wong, KK | 1 |
| Cheetham, TC | 1 |
| Feldman, MJ | 1 |
| Sharon, D | 1 |
| Golimbu, M | 1 |
| Morales, P | 1 |
| Becker, MH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessing the Longitudinal Outcomes of Piperacillin/Tazobactam Versus ceftriAxone and Metronidazole for Children With Perforated Appendicitis (ALPACA): a Randomized Controlled Trial[NCT05943223] | Phase 2 | 16 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| PROTOP: Study of the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Localization Infection in Colorectal Surgery[NCT03574090] | Phase 4 | 268 participants (Actual) | Interventional | 2020-10-20 | Completed | ||
| Collagen-Gentamicin Implant in the Treatment of Contaminated Surgical Abdominal Wounds - A Randomized Controlled Trial[NCT00977405] | Phase 2 | 70 participants (Anticipated) | Interventional | 2009-09-30 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for gentamicin and Appendicitis
| Article | Year |
|---|---|
Antibiotic prophylaxis in acute non-perforated appendicitis in children: single dose of metronidazole and gentamicin.
Topics: Acute Disease; Adolescent; Appendicitis; Child; Child, Preschool; Female; Gentamicins; Humans; Male; | 1992 |
31 trials available for gentamicin and Appendicitis
| Article | Year |
|---|---|
A randomized controlled trial on irrigation of open appendectomy wound with gentamicin- saline solution versus saline solution for prevention of surgical site infection.
Topics: Acute Disease; Adolescent; Adult; Appendectomy; Appendicitis; Double-Blind Method; Female; Gentamici | 2020 |
Ertapenem versus standard triple antibiotic therapy for the treatment of perforated appendicitis in pediatric patients: a prospective randomized trial.
Topics: Adolescent; Ampicillin; Anti-Bacterial Agents; Appendectomy; Appendicitis; beta-Lactams; Child; Chil | 2014 |
Initial antibiotic treatment for acute simple appendicitis in children is safe: Short-term results from a multicenter, prospective cohort study.
Topics: Adolescent; Amoxicillin-Potassium Clavulanate Combination; Appendectomy; Appendicitis; beta-Lactamas | 2015 |
Single daily dosing ceftriaxone and metronidazole vs standard triple antibiotic regimen for perforated appendicitis in children: a prospective randomized trial.
Topics: Abscess; Administration, Oral; Adolescent; Antibiotic Prophylaxis; Appendectomy; Appendicitis; Ceftr | 2008 |
[Prospective study comparing the incidence of wound infection following appendectomy for acute appendicitis in children: conventional treatment versus using reabsorbable antibacterial suture or gentamicin-impregnated collagen fleeces].
Topics: Adolescent; Anti-Bacterial Agents; Appendectomy; Appendicitis; Bandages; Child; Child, Preschool; Co | 2008 |
The influence of weight with assay error on gentamicin pharmacokinetics using the Bayesian and nonlinear least square regression analysis in appendicitis patients.
Topics: Anti-Bacterial Agents; Appendicitis; Bayes Theorem; Body Weight; Gentamicins; Half-Life; Humans; Kor | 2005 |
Antibiotic management of surgically treated gangrenous or perforated appendicitis. Comparison of gentamicin and clindamycin versus cefamandole versus cefoperazone.
Topics: Adolescent; Adult; Aged; Appendicitis; Cefamandole; Cefoperazone; Cephalosporins; Clindamycin; Clini | 1982 |
Antibiotic prophylaxis in acute appendicitis.
Topics: Acute Disease; Administration, Oral; Adolescent; Appendectomy; Appendicitis; Clinical Trials as Topi | 1983 |
Comparison of cefuroxime and gentamicin in combination with metronidazole in the treatment of peritonitis due to perforation of the appendix.
Topics: Adult; Appendicitis; Bacteria; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Drug Therapy, C | 1983 |
Antibiotic management of complicated appendicitis.
Topics: Ampicillin; Appendicitis; Child; Clindamycin; Clinical Trials as Topic; Double-Blind Method; Drug Th | 1983 |
Combined preoperative antibiotic therapy and intraoperative topical povidone-iodine. Reduction of wound sepsis following emergency appendectomy.
Topics: Administration, Topical; Adolescent; Adult; Appendectomy; Appendicitis; Clindamycin; Clinical Trials | 1984 |
[Logical use of prophylactic antibacterial agents in infectious post-appendectomy complications. A controlled clinical trial].
Topics: Appendectomy; Appendicitis; Bacterial Infections; Child; Clindamycin; Clinical Trials as Topic; Fema | 1982 |
Prospective, randomized comparison of metronidazole and clindamycin, each with gentamicin, for the treatment of serious intra-abdominal infection.
Topics: Abdomen; Abscess; Adolescent; Adult; Aged; Anti-Bacterial Agents; Appendicitis; Bacterial Infections | 1983 |
Perforated appendix and antibiotics.
Topics: Anti-Bacterial Agents; Appendicitis; Child; Clindamycin; Drug Therapy, Combination; Gentamicins; Hum | 1981 |
[A randomized prospective study of antibiotic prophylaxis compared to lavage of the surgical wound in nonperforating appendicitis].
Topics: Acute Disease; Adolescent; Adult; Appendectomy; Appendicitis; Chi-Square Distribution; Child; Female | 1994 |
A clinical comparison of cefepime and metronidazole versus gentamicin and clindamycin in the antibiotic management of surgically treated advanced appendicitis.
Topics: Adolescent; Adult; Appendicitis; Cefepime; Cephalosporins; Clindamycin; Double-Blind Method; Drug Ad | 1993 |
Prospective randomized study of piperacillin/tazobactam therapy of surgically treated intra-abdominal infection. The Piperacillin/Tazobactam Intra-Abdominal Infection Study Group.
Topics: Abdomen; Abscess; Adolescent; Adult; Aged; Aged, 80 and over; Appendicitis; Bacterial Infections; be | 1993 |
Prospective randomized study of two different doses of clindamycin admixed with gentamicin in the management of perforated appendicitis.
Topics: Adult; Appendicitis; Bacterial Infections; Clindamycin; Drug Administration Schedule; Drug Therapy, | 1993 |
Penetration of clindamycin and metronidazole into inflamed appendiceal tissue.
Topics: Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Appendicitis; Appendix; Clindamycin; Drug Ther | 1996 |
Effectiveness of collagen-gentamicin implant for treatment of "dirty" abdominal wounds.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local; | 1999 |
Results of a pilot trial comparing prolonged intravenous antibiotics with sequential intravenous/oral antibiotics for children with perforated appendicitis.
Topics: Administration, Oral; Adolescent; Ampicillin; Appendicitis; Child; Child, Preschool; Clavulanic Acid | 2001 |
Antibiotic prophylaxis in acute non-perforated appendicitis in children: single dose of metronidazole and gentamicin.
Topics: Acute Disease; Adolescent; Appendicitis; Child; Child, Preschool; Female; Gentamicins; Humans; Male; | 1992 |
Analysis of cefepime tissue penetration into human appendix.
Topics: Adolescent; Adult; Appendectomy; Appendicitis; Appendix; Ascitic Fluid; Cefepime; Cephalosporins; Cl | 1991 |
A randomized clinical trial of ampicillin, gentamicin and clindamycin versus cefotaxime and clindamycin in children with ruptured appendicitis.
Topics: Adolescent; Ampicillin; Appendicitis; Cefotaxime; Child; Child, Preschool; Clindamycin; Combined Mod | 1991 |
One-drug versus two-drug antibiotic therapy in pediatric perforated appendicitis: a prospective randomized study.
Topics: Adolescent; Appendicitis; Bacterial Infections; Cefoxitin; Child; Child, Preschool; Clindamycin; Dru | 1991 |
A randomized trial of ticarcillin and clavulanate versus gentamicin and clindamycin in patients with complicated appendicitis.
Topics: Abdomen; Abscess; Adolescent; Adult; Anti-Bacterial Agents; Appendicitis; beta-Lactamase Inhibitors; | 1991 |
The role of Pseudomonas species in patients treated with ampicillin and Sulbactam for gangrenous and perforated appendicitis.
Topics: Adult; Ampicillin; Appendicitis; Clindamycin; Double-Blind Method; Drug Therapy, Combination; Female | 1985 |
Stratified duration of prophylactic antimicrobial treatment in emergency abdominal surgery. Metronidazole-fosfomycin vs. metronidazole-gentamicin in 381 patients.
Topics: Abdomen, Acute; Adolescent; Adult; Aged; Appendicitis; Cholecystitis; Clinical Trials as Topic; Drug | 1987 |
Surgically treated gangrenous or perforated appendicitis. A comparison of aztreonam and clindamycin versus gentamicin and clindamycin.
Topics: Adult; Appendicitis; Aztreonam; Clindamycin; Clinical Trials as Topic; Double-Blind Method; Drug The | 1987 |
Cefoxitin versus gentamicin and metronidazole in prevention of post-appendicectomy sepsis: a randomized, prospective trial.
Topics: Adolescent; Adult; Appendectomy; Appendicitis; Bacterial Infections; Cefoxitin; Drug Therapy, Combin | 1986 |
Cost analysis of antibiotics in the management of perforated or gangrenous appendicitis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Appendicitis; Cefamandole; Cefoperazone; Clindamycin; Cost | 1986 |
37 other studies available for gentamicin and Appendicitis
| Article | Year |
|---|---|
Dual versus Triple Antibiotics Regimen in Children with Perforated Acute Appendicitis.
Topics: Acute Disease; Ampicillin; Anti-Bacterial Agents; Appendectomy; Appendicitis; Ceftriaxone; Chemother | 2018 |
Simplification of first-line antibacterial regimen for complicated appendicitis in children is associated with better adherence to guidelines and reduced use of antibiotics.
Topics: Adolescent; Anti-Bacterial Agents; Appendicitis; Cefotaxime; Child; Drug Therapy, Combination; Femal | 2018 |
Adequacy of antibiotic prophylaxis protocol in appendectomies in children.
Topics: Acute Disease; Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Antibiotic Prophylaxis; Ap | 2019 |
Successful treatment of acute uncomplicated appendicitis in pregnancy with intravenous antibiotics.
Topics: Administration, Oral; Adult; Amoxicillin-Potassium Clavulanate Combination; Appendicitis; Female; Ge | 2013 |
The microbiology of bacterial peritonitis due to appendicitis in children.
Topics: Adolescent; Aminoglycosides; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; A | 2014 |
Acute perforative appendicitis during preoperative chemotherapy for Wilms tumor.
Topics: Abdominal Pain; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Appendicitis; Ceftazi | 2003 |
Appendicitis in children: a ten-year update of therapeutic recommendations.
Topics: Abdominal Abscess; Acute Disease; Adolescent; Ampicillin; Antibiotic Prophylaxis; Appendectomy; Appe | 2003 |
[Acute catarrhal appendicitis: is appendectomy required?].
Topics: Animals; Anti-Bacterial Agents; Appendicitis; Gentamicins; Humans; Low-Level Light Therapy; Peritone | 2004 |
Monotherapy versus multi-drug therapy for the treatment of perforated appendicitis in children.
Topics: Ampicillin; Appendectomy; Appendicitis; Child; Clindamycin; Drug Combinations; Drug Therapy, Combina | 2003 |
The influence of assay error weight on gentamicin pharmacokinetics using the Bayesian and nonlinear least square regression analysis in appendicitis patients.
Topics: Anti-Bacterial Agents; Appendicitis; Bayes Theorem; Body Weight; Female; Gentamicins; Humans; Least- | 2005 |
Cure of persistent, post-appendectomy Klebsiella pneumoniae septicaemia with continuous intravenous administration of meropenem.
Topics: Adolescent; Anti-Bacterial Agents; Appendectomy; Appendicitis; Drug Therapy, Combination; Female; Fe | 2006 |
Perforated and gangrenous appendicitis: an analysis of antibiotic failures.
Topics: Anti-Bacterial Agents; Appendicitis; Bacteroides fragilis; Bacteroides Infections; Cefamandole; Cefo | 1983 |
Wound infections in appendicitis: effective prophylaxis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Appendectomy; Appendicitis; Child; Clindamycin; Female; Ge | 1984 |
Gentamicin penetration into diseased appendix tissue.
Topics: Adult; Appendicitis; Appendix; Body Fluids; Gentamicins; Humans; Middle Aged; Premedication | 1984 |
Rational use of antibiotics for perforated appendicitis in childhood.
Topics: Abscess; Adolescent; Ampicillin; Anti-Bacterial Agents; Appendicitis; Child; Child, Preschool; Clind | 1982 |
Intraperitoneal gentamicin in appendiceal peritonitis in children: a pharmacokinetic study.
Topics: Acute Disease; Adolescent; Appendicitis; Child; Child, Preschool; Dose-Response Relationship, Drug; | 1981 |
[Peritoneal lavage in diffuse peritonitis originating from perforated appendix].
Topics: Adult; Aged; Ampicillin; Appendicitis; Clindamycin; Female; Gentamicins; Humans; Intestinal Perforat | 1980 |
[Prevention of suppurative complications of appendiceal peritonitis (author's transl)].
Topics: Anti-Bacterial Agents; Appendicitis; Clindamycin; Drug Therapy, Combination; Gentamicins; Humans; Pe | 1980 |
Management of appendicular mass in children.
Topics: Ampicillin; Appendectomy; Appendicitis; Child; Drug Therapy, Combination; Female; Follow-Up Studies; | 1993 |
[Endolymphatic drug infusion in the treatment of complicated acute appendicitis].
Topics: Abscess; Acute Disease; Anti-Bacterial Agents; Appendicitis; Aprotinin; Aspirin; Cefotaxime; Ceftazi | 1993 |
[Method of indirect intralymphatic antibiotic therapy in acute appendicitis].
Topics: Acute Disease; Anti-Bacterial Agents; Appendicitis; Gentamicins; Humans; Indigo Carmine; Injections, | 1994 |
[Endolymphatic therapy in the treatment of patients with acute appendicitis].
Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Appendicitis; Carbe | 1996 |
[Endolymphatic therapy in the treatment of patients with acute appendicitis].
Topics: Acute Disease; Adjuvants, Immunologic; Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophyla | 1996 |
Gentamicin-induced Bartter-like syndrome.
Topics: Adolescent; Anti-Bacterial Agents; Appendicitis; Bartter Syndrome; Child; Enterocolitis; Escherichia | 1997 |
Influence of diagnostic and treatment factors in the population pharmacokinetics of gentamicin.
Topics: Abscess; Adult; Appendicitis; Cholecystitis; Colonic Neoplasms; Drug Interactions; Female; Gentamici | 1998 |
Monitoring of aminoglycoside serum concentrations.
Topics: Adolescent; Adult; Age Factors; Anti-Bacterial Agents; Appendicitis; Child; Child, Preschool; Drug M | 2000 |
Comparison of two antibiotic regimens in the treatment of perforated appendicitis in pediatric patients.
Topics: Adolescent; Ampicillin; Anti-Bacterial Agents; Appendicitis; Child; Child, Preschool; Clavulanic Aci | 2000 |
Bacteriological survey of acute appendicitis in children.
Topics: Adolescent; Anti-Bacterial Agents; Appendicitis; Bacteria; Bacterial Infections; Bacteriological Tec | 1976 |
Use of clindamycin and gentamicin in pediatric colonic surgery.
Topics: Appendicitis; Bacterial Infections; Bacteroides fragilis; Child; Child, Preschool; Clindamycin; Colo | 1976 |
Bacterial flora of appendicitis in children.
Topics: Aerobiosis; Amikacin; Anaerobiosis; Appendectomy; Appendicitis; Ascitic Fluid; Bacteria; Cephalothin | 1976 |
Use of gentamicin clearance in estimating renal function.
Topics: Adolescent; Adult; Appendicitis; Body Weight; Creatinine; Female; Gentamicins; Humans; Kidney Functi | 1991 |
[Antibacterial activity of nitazole and its use in combined treatment of appendicular peritonitis in children].
Topics: Anti-Bacterial Agents; Appendicitis; Child; Drug Therapy, Combination; Gentamicins; Humans; Peritoni | 1990 |
Imipenem therapy for perforated and gangrenous appendicitis.
Topics: Adult; Aged; Appendectomy; Appendicitis; Ascitic Fluid; Cilastatin; Clindamycin; Cyclopropanes; Drug | 1986 |
Antimicrobial management of surgically treated gangrenous or perforated appendicitis: comparison of cefoxitin and clindamycin-gentamicin.
Topics: Adolescent; Adult; Aged; Appendectomy; Appendicitis; Appendix; Cefoxitin; Child; Child, Preschool; C | 1987 |
Comparison of four methods for predicting serum gentamicin concentrations in surgical patients with perforated or gangrenous appendicitis.
Topics: Adult; Appendicitis; Female; Gangrene; Gentamicins; Humans; Intestinal Perforation; Male | 1987 |
Matched case-control study of adjusted versus nonadjusted gentamicin dosing in perforated and gangrenous appendicitis.
Topics: Adult; Appendicitis; Dose-Response Relationship, Drug; Female; Gangrene; Gentamicins; Humans; Intest | 1986 |
Ureteroappendiceal fistula in child.
Topics: Antineoplastic Agents; Appendicitis; Appendix; Child, Preschool; Female; Gentamicins; Humans; Intest | 1974 |