gentamicin has been researched along with Anoxia-Ischemia, Brain in 9 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gentamicin clearance is decreased in neonates with HIE receiving hypothermia treatment compared to those not receiving hypothermia treatment." | 8.98 | Effect of hypothermia treatment on gentamicin pharmacokinetics in neonates with hypoxic-ischaemic encephalopathy: A systematic review and meta-analysis. ( An, SH; Choi, DW; Lee, SY; Park, JH, 2018) |
| "Gentamicin clearance is decreased in neonates with HIE receiving hypothermia treatment compared to those not receiving hypothermia treatment." | 4.98 | Effect of hypothermia treatment on gentamicin pharmacokinetics in neonates with hypoxic-ischaemic encephalopathy: A systematic review and meta-analysis. ( An, SH; Choi, DW; Lee, SY; Park, JH, 2018) |
| " The results indicated that long-term VI-28 treatment invariably protected against oxidative tissue damage in the rat models of cerebral/myocardial ischemia-reperfusion injury, CCl4 hepatotoxicity, and gentamicin nephrotoxicity." | 3.74 | Long-term treatment with a Yang-invigorating Chinese herbal formula produces generalized tissue protection against oxidative damage in rats. ( Chen, N; Chiu, PY; Ko, KM; Leung, HY; Poon, MK; Siu, AH, 2008) |
| "Little is known about the pharmacokinetic (PK) properties of gentamicin in newborns undergoing controlled hypothermia after suffering from hypoxic−ischaemic encephalopathy due to perinatal asphyxia." | 1.43 | Altered gentamicin pharmacokinetics in term neonates undergoing controlled hypothermia. ( Bijleveld, YA; Cools, F; de Haan, TR; de Jonge, RC; Dijk, PH; Dijkman, KP; Groenendaal, F; Mathot, RA; Nuytemans, DH; Rijken, M; van der Lee, HJ; van Heijst, A; van Kaam, AH; van Straaten, HL; Zecic, A; Zonnenberg, IA, 2016) |
| "Gentamicin was given at 2." | 1.42 | Pharmacokinetics of gentamicin in newborns with moderate-to-severe hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia. ( Kwan, E; McDougal, A; Osiovich, H; Ting, JY, 2015) |
| "Population pharmacokinetic study using retrospective medical record data." | 1.39 | Gentamicin pharmacokinetics and dosing in neonates with hypoxic ischemic encephalopathy receiving hypothermia. ( Bonifacio, SL; Frymoyer, A; Guglielmo, BJ; Meng, L; Verotta, D, 2013) |
| "Neonates with an elevated trough concentration >2 mg l(-1) decreased from 38 to 4% with implementation of a Q36-h dosing interval (P<0." | 1.39 | Every 36-h gentamicin dosing in neonates with hypoxic-ischemic encephalopathy receiving hypothermia. ( Bonifacio, SL; Frymoyer, A; Guglielmo, BJ; Lee, S; Lucas, SS; Meng, L; Sun, Y; Verotta, D, 2013) |
| " Based on these findings, we propose changes in gentamicin dosing interval and trough level monitoring to minimize the risk of potentially toxic levels in cooled newborns." | 1.39 | Factors associated with permanent hearing impairment in infants treated with therapeutic hypothermia. ( Gill, H; Jary, S; Liu, X; Sabir, H; Smit, E; Thoresen, M, 2013) |
| " Once-daily gentamicin dosage (4-5 mg/kg) was administered, and trough SGC was recorded with corresponding creatinine concentrations." | 1.35 | Serum gentamicin concentrations in encephalopathic infants are not affected by therapeutic hypothermia. ( Borooah, M; Chakkarapani, E; Liu, X; Stone, J; Thoresen, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, DW | 1 |
| Park, JH | 1 |
| Lee, SY | 1 |
| An, SH | 1 |
| Frymoyer, A | 2 |
| Meng, L | 2 |
| Bonifacio, SL | 2 |
| Verotta, D | 2 |
| Guglielmo, BJ | 2 |
| Lee, S | 1 |
| Lucas, SS | 1 |
| Sun, Y | 1 |
| Smit, E | 1 |
| Liu, X | 2 |
| Gill, H | 1 |
| Sabir, H | 1 |
| Jary, S | 1 |
| Thoresen, M | 2 |
| Ting, JY | 1 |
| Kwan, E | 1 |
| McDougal, A | 1 |
| Osiovich, H | 1 |
| Bijleveld, YA | 1 |
| de Haan, TR | 1 |
| van der Lee, HJ | 1 |
| Groenendaal, F | 1 |
| Dijk, PH | 1 |
| van Heijst, A | 1 |
| de Jonge, RC | 1 |
| Dijkman, KP | 1 |
| van Straaten, HL | 1 |
| Rijken, M | 1 |
| Zonnenberg, IA | 1 |
| Cools, F | 1 |
| Zecic, A | 1 |
| Nuytemans, DH | 1 |
| van Kaam, AH | 1 |
| Mathot, RA | 1 |
| Whitla, L | 1 |
| Fitzgerald, D | 1 |
| Twomey, A | 1 |
| Knowles, S | 1 |
| Murphy, JF | 1 |
| Borooah, M | 1 |
| Stone, J | 1 |
| Chakkarapani, E | 1 |
| Chiu, PY | 1 |
| Leung, HY | 1 |
| Siu, AH | 1 |
| Chen, N | 1 |
| Poon, MK | 1 |
| Ko, KM | 1 |
1 review available for gentamicin and Anoxia-Ischemia, Brain
| Article | Year |
|---|---|
Effect of hypothermia treatment on gentamicin pharmacokinetics in neonates with hypoxic-ischaemic encephalopathy: A systematic review and meta-analysis.
Topics: Birth Weight; Creatinine; Dose-Response Relationship, Drug; Female; Gentamicins; Gestational Age; Hu | 2018 |
8 other studies available for gentamicin and Anoxia-Ischemia, Brain
| Article | Year |
|---|---|
Gentamicin pharmacokinetics and dosing in neonates with hypoxic ischemic encephalopathy receiving hypothermia.
Topics: Anti-Bacterial Agents; Birth Weight; Creatinine; Dose-Response Relationship, Drug; Drug Administrati | 2013 |
Every 36-h gentamicin dosing in neonates with hypoxic-ischemic encephalopathy receiving hypothermia.
Topics: Anti-Bacterial Agents; Female; Gentamicins; Gestational Age; Humans; Hypothermia, Induced; Hypoxia-I | 2013 |
Factors associated with permanent hearing impairment in infants treated with therapeutic hypothermia.
Topics: Brain Diseases; Female; Gentamicins; Hearing Loss; Humans; Hydrogen-Ion Concentration; Hypoglycemia; | 2013 |
Pharmacokinetics of gentamicin in newborns with moderate-to-severe hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Dosage C | 2015 |
Altered gentamicin pharmacokinetics in term neonates undergoing controlled hypothermia.
Topics: Anti-Bacterial Agents; Cohort Studies; Computer Simulation; Female; Fetal Hypoxia; Gentamicins; Gest | 2016 |
Gentamicin Dosing in Therapeutic Hypothermia; a Quality Improvement Initiative.
Topics: Anti-Bacterial Agents; Body Temperature; Female; Gentamicins; Humans; Hypothermia, Induced; Hypoxia- | 2016 |
Serum gentamicin concentrations in encephalopathic infants are not affected by therapeutic hypothermia.
Topics: Body Temperature; Creatinine; Evoked Potentials, Auditory, Brain Stem; Female; Gentamicins; Humans; | 2009 |
Long-term treatment with a Yang-invigorating Chinese herbal formula produces generalized tissue protection against oxidative damage in rats.
Topics: Animals; Carbon Tetrachloride; Carnosine; Chemical and Drug Induced Liver Injury; Cholecalciferol; C | 2008 |