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gentamicin and Anemia

gentamicin has been researched along with Anemia in 14 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.

Research Excerpts

ExcerptRelevanceReference
"In an attempt to assess the erythropoietin (Epo) production site(s) in rat kidney, Epo response to hypoxia and renal histopathological changes were studied in rats administered with graded doses of gentamicin."7.69Erythropoietin response to acute hypobaric or anaemic hypoxia in gentamicin-administered rats. ( Enoki, Y; Kohzuki, H; Matsumura, K; Ohga, Y; Sakata, S; Shimizu, S, 1994)
"The practice of locking newly inserted tunneled central venous catheters with gentamicin and heparin is an effective strategy to reduce line sepsis rates, and is associated with beneficial effects on epoetin requirements."5.11Locking of tunneled hemodialysis catheters with gentamicin and heparin. ( Fluck, RJ; Hulme, LJ; McIntyre, CW; Taal, M, 2004)
"In an attempt to assess the erythropoietin (Epo) production site(s) in rat kidney, Epo response to hypoxia and renal histopathological changes were studied in rats administered with graded doses of gentamicin."3.69Erythropoietin response to acute hypobaric or anaemic hypoxia in gentamicin-administered rats. ( Enoki, Y; Kohzuki, H; Matsumura, K; Ohga, Y; Sakata, S; Shimizu, S, 1994)
" Similar findings were obtained in rats with CCl4 liver damage or gentamicin nephrotoxicity, except that those rats hardly exhibited anemia because of a simultaneous occurrence of hemoconcentration."3.67The influence of single or repeated phlebotomy on the physiological condition of normal and diseased rats. ( Furuhama, K; Igarashi, K; Kato, M; Onodera, T; Suzuki, N, 1987)
"The severe adverse events observed in patients who received hemoglobin based oxygen carriers (HBOCs) were associated with the Ringer's D."1.35The effects of preserved red blood cells on the severe adverse events observed in patients infused with hemoglobin based oxygen carriers. ( Ragno, G; Valeri, CR, 2008)
" Caution should be exercised during long-term use because production of antibodies to human recombinant and endogenous erythropoietin may lead to potentially serious side effects."1.31Use of human recombinant erythropoietin for the treatment of nonregenerative anemia in a rough-toothed dolphin (Steno bredanensis). ( Manire, CA; Rhinehart, HL, 2000)
"Leukopenia was found in 51% of children and anaemia in 24%."1.30Brucellosis in children in south Jordan. ( Issa, H; Jamal, M, 1999)
"Bacteremia was documented in 14 of 156 previously healthy children with temperatures of at least 40."1.29Acute fevers of unknown origin in young children in the tropics. ( Abiodun, PO; Akpede, GO; Sykes, RM, 1993)
"Gentamicin-treated rats showed marked elevation of blood urea nitrogen, extensive tubular necrosis in the kidney and haemosiderin deposition in the spleen."1.28Effect of recombinant human erythropoietin on new anaemic model rats induced by gentamicin. ( Arai, H; Koumegawa, J; Kusaka, M; Nagano, N; Wada, M, 1990)
"Peak concentrations and half-life of gentamicin in serum were measured after 140 intravenous and 13 intramuscular doses in 52 children and 17 adults with normal levels of creatinine in serum."1.25Pharmacokinetics of gentamicin in children and adults. ( Echeverria, P; Paisley, JW; Siber, GR; Smith, AL; Smith, DH, 1975)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's5 (35.71)18.2507
2000's5 (35.71)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ribas, N1
Arribas, C1
Murillas, J1
Natarajan, A1
Hindocha, D1
Kular, N1
Fergey, S1
Davis, JR1
McIntyre, CW1
Hulme, LJ1
Taal, M1
Fluck, RJ1
Valeri, CR1
Ragno, G1
Shimizu, S1
Enoki, Y1
Sakata, S1
Kohzuki, H1
Ohga, Y1
Matsumura, K1
Akpede, GO1
Abiodun, PO1
Sykes, RM1
Manire, CA1
Rhinehart, HL1
Issa, H1
Jamal, M1
Kalaidjieva, VC1
Iliev, ZK1
Siber, GR1
Echeverria, P1
Smith, AL1
Paisley, JW1
Smith, DH1
Delb, W1
Koch, A1
Federspil, P1
Nagano, N1
Koumegawa, J1
Arai, H1
Wada, M1
Kusaka, M1
Furuhama, K1
Kato, M1
Suzuki, N1
Igarashi, K1
Onodera, T1
Stille, W1
Arndt, I1

Reviews

1 review available for gentamicin and Anemia

ArticleYear
[Streptococcus agalactiae tricuspid valve endocarditis. A case report and review of literature].
    Enfermedades infecciosas y microbiologia clinica, 2009, Volume: 27, Issue:3

    Topics: Adult; Anemia; Anti-Bacterial Agents; Bacteremia; Blood Transfusion; Endocarditis, Bacterial; Fever;

2009

Trials

1 trial available for gentamicin and Anemia

ArticleYear
Locking of tunneled hemodialysis catheters with gentamicin and heparin.
    Kidney international, 2004, Volume: 66, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Anti-Bacterial Agents; Anticoagulants; Catheterization; Cros

2004

Other Studies

12 other studies available for gentamicin and Anemia

ArticleYear
Vasculitic rash: do not jump to conclusions.
    Clinical medicine (London, England), 2012, Volume: 12, Issue:2

    Topics: Amoxicillin; Anemia; Anti-Bacterial Agents; Aortic Valve; Diagnosis, Differential; Echocardiography,

2012
The effects of preserved red blood cells on the severe adverse events observed in patients infused with hemoglobin based oxygen carriers.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2008, Volume: 36, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenine; Adenosine Triphosphate; Anemia; Blood Preservation; Blood Substitut

2008
Erythropoietin response to acute hypobaric or anaemic hypoxia in gentamicin-administered rats.
    Acta physiologica Scandinavica, 1994, Volume: 151, Issue:2

    Topics: Anemia; Animals; Atmospheric Pressure; Blood Volume; Erythropoietin; Gentamicins; Hypoxia; Kidney Tu

1994
Acute fevers of unknown origin in young children in the tropics.
    The Journal of pediatrics, 1993, Volume: 122, Issue:1

    Topics: Acute Disease; Age Factors; Ampicillin; Anemia; Bacteremia; Child, Preschool; Cloxacillin; Diagnosis

1993
Use of human recombinant erythropoietin for the treatment of nonregenerative anemia in a rough-toothed dolphin (Steno bredanensis).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2000, Volume: 31, Issue:2

    Topics: Anemia; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Dolphins; Enzyme-Linked Immunosorbent Ass

2000
Brucellosis in children in south Jordan.
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 1999, Volume: 5, Issue:5

    Topics: Adolescent; Anemia; Animals; Anti-Bacterial Agents; Arthralgia; Brucellosis; Child; Child, Preschool

1999
Plasma erythropoietin level in rats after kidney proximal tubular impairment.
    Folia medica, 2000, Volume: 42, Issue:3

    Topics: Anemia; Animals; Disease Models, Animal; Erythropoiesis; Erythropoietin; Gentamicins; Hematologic Te

2000
Pharmacokinetics of gentamicin in children and adults.
    The Journal of infectious diseases, 1975, Volume: 132, Issue:6

    Topics: Adolescent; Adult; Age Factors; Anemia; Bacterial Infections; Child; Child, Preschool; Creatinine; D

1975
Experimental investigations on the influence of anemia on gentamicin ototoxicity.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1991, Volume: 248, Issue:6

    Topics: Anemia; Anemia, Hypochromic; Animals; Auditory Threshold; Blood Proteins; Bloodletting; Cochlea; Cre

1991
Effect of recombinant human erythropoietin on new anaemic model rats induced by gentamicin.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:11

    Topics: Anemia; Animals; Blood Volume; Erythropoietin; Gentamicins; Hematocrit; Kidney Tubular Necrosis, Acu

1990
The influence of single or repeated phlebotomy on the physiological condition of normal and diseased rats.
    The Journal of toxicological sciences, 1987, Volume: 12, Issue:1

    Topics: Anemia; Animals; Blood Cell Count; Blood Pressure; Bloodletting; Carbon Tetrachloride; Chemical and

1987
[Arguments against the nephrotoxicity of cephalothin and gentamicin].
    Die Medizinische Welt, 1972, Oct-28, Volume: 23, Issue:44

    Topics: Adolescent; Adult; Aged; Anemia; Cephalothin; Drug Combinations; Female; Gentamicins; Humans; Kidney

1972