Page last updated: 2024-10-27

gentamicin and Agranulocytosis

gentamicin has been researched along with Agranulocytosis in 91 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
"A 46-year-old man with pentazocine-induced agranulocytosis is described."7.67Pentazocine-induced agranulocytosis. ( Doggett, JJ; Haibach, H; Yesus, YW, 1984)
"To minimize renal and hematological toxicity during empirical antibiotic therapy for pediatric patients with fever and neutropenia, piperacillin and gentamicin combination therapy was evaluated."7.67Piperacillin and gentamicin as non toxic empirical therapy in pediatric patients with fever and neutropenia. ( Clavell, LA; González, M, 1987)
"To assess the efficacy of single-agent therapy relative to standard combination antibiotic therapy for the initial management of fever and neutropenia in cancer patients, we conducted a randomized trial comparing ceftazidime alone with a combination of cephalothin, gentamicin, and carbenicillin."5.06A randomized trial comparing ceftazidime alone with combination antibiotic therapy in cancer patients with fever and neutropenia. ( Browne, M; Commers, J; Cotton, D; Gress, J; Hathorn, JW; Hiemenz, J; Longo, D; Marshall, D; McKnight, J; Pizzo, PA, 1986)
"Ceftazidime was compared with a combination of cephalothin, carbenicillin and gentamicin as empirical therapy for fever in granulocytopenic patients."5.05Early results of a comparative trial of ceftazidime versus cephalothin, carbenicillin and gentamicin in the treatment of febrile granulocytopenic patients. ( Kramer, BS; Ramphal, R; Rand, KH; Shands, JW; Weiner, RS, 1983)
"Random allocation of 22 patients with benign and malignant diseases with neutrophil counts of up to 1 X 10(9)/l blood and probably infection-caused fever of more than 38 degrees C to intravenous treatment with one of the following antibiotic combinations was performed: carbenicillin (6 g/m(2) ."5.05[Treatment of severe febrile neutropenia (author's transl)]. ( Heim, ME; Meuret, G; Roux, A; Westerhausen, M, 1980)
"Thirty-six patients with severe aplastic anemia or acute leukemia undergoing bone marrow transplantation or intensive hematologic treatments were randomized to receive gentamicin (1 mg/kg/iv q8h) or tobramycin (1 mg/kg/iv q8h) in combination with carbenecillin (500 mg/kg/day i."5.05Tobramycin versus gentamicin, in combination with cephalotin and carbenecillin, in patients undergoing bone marrow transplantation. ( Bacigalupo, A; Frassoni, F; Grazi, G; Marmont, A; Podestà, M; Soro, O; Van Lint, MT; Volta, C, 1981)
"Neutropenic cancer patients were given carbenicillin, cephalothin, and gentamicin (CCG) during 51 evaluable episodes of fever of unknown origin."5.04A study of antibiotic therapy in fever of unknown origin in neutropenic cancer patients. ( Björnsson, S; Henderson, ES; Preisler, H, 1977)
"A 46-year-old man with pentazocine-induced agranulocytosis is described."3.67Pentazocine-induced agranulocytosis. ( Doggett, JJ; Haibach, H; Yesus, YW, 1984)
"To minimize renal and hematological toxicity during empirical antibiotic therapy for pediatric patients with fever and neutropenia, piperacillin and gentamicin combination therapy was evaluated."3.67Piperacillin and gentamicin as non toxic empirical therapy in pediatric patients with fever and neutropenia. ( Clavell, LA; González, M, 1987)
"A three drug regimen of carbenicillin, cefazolin and gentamicin was used for the treatment of patients with solid tumors, who developed fever while granulocytopenic following chemotherapy."3.66Treatment of febrile granuloycytopenic cancer patients receiving antineoplastic therapy with a combination of carbenicillin, cefazolin and gentamicin. ( Catane, R; Fuks, Z; Halpern, J; Sacks, T, 1983)
"During a 20-month period all acute nonlymphocytic patients (87 patient trials) receiving cytotoxic chemotherapy were placed on an oral nonabsorbable antibiotic regimen consisting of gentamicin, vancomycin, and nystatin in addition to an intensive program of infection prevention aimed at reducing exogenously acquired and body-surface potential pathogens."3.66Infection in acute leukemia patients receiving oral nonabsorable antibiotics. ( Fortner, CL; Hahn, DM; Schimpff, SC; Smyth, AC; Wiernik, PH; Young, VM, 1978)
"Patients with myelotoxic agranulocytosis were treated with gentamicin administered intravenously as drop-wise infusions in a dose of 5 mg/kg body weight a day every 8 hours."3.66[Gentamycin sulfate effectiveness and tolerance in patients with myelotoxic agranulocytosis]. ( Baranov, AE; Bodunkova, LE; Nadezhina, NM; Pozdniakova, VP; Shishkova, TV, 1979)
" Monotherapy with ceftazidime is as effective as when used in combination with an aminoglycoside in neutropenia."2.67Ceftazidime monotherapy is as effective as ceftazidime combined with gentamicin in the treatment of febrile neutropenic patients. ( Goldstone, AH; Kinsey, SE; Machin, SJ, 1990)
"The response rate for all infections was 97 per cent in group 1, 91 per cent in group 2 and 95 per cent in group 3."2.65Randomized trial of empiric antibiotic therapy with ticarcillin in combination with gentamicin, amikacin or netilmicin in febrile patients with granulocytopenia and cancer. ( Bender, JF; Fortner, CL; Hahn, DM; Love, LJ; Schimpff, SC; Standiford, HC; Wiernik, PH; Young, VM, 1979)
"Ticarcillin was used in combination with either cephalothin or gentamicin as initial empiric antibiotic therapy for 127 patient trials of suspected infection in granulocytopenic cancer patients."2.64Ticarcillin in combination with cephalothin or gentamicin as empiric antibiotic therapy in granulocytopenic cancer patients. ( Fortner, CL; Hahn, DM; Landesman, S; Schimpff, SC; Standiford, HC; Wiernik, PH; Young, VM, 1976)
"Antibiotic therapy in granulocytopenic cancer patients, the risk factors predisposing these patients to infection, and the signs, symptoms and types of infections occurring in these patients are reviewed."2.36Empiric therapy of febrile granulocytopenic patients. ( Hopefl, AW, 1979)
"Although granulocytopenia is relatively common in the later stages of HIV infection, it has only been described once before in the acute stage."1.29Granulocytopenia secondary to acute infection with the human immunodeficiency virus. ( King, ME; Skiest, DJ, 1994)
" No pharmacokinetic differences were seen in half-life, volume of distribution (liter per kilogram; total and ideal body weight), or clearance (milliliter per minute per 1."1.28Gentamicin pharmacokinetics, nephrotoxicity, and prediction of mortality in febrile neutropenic patients. ( Bertino, JS; Bianco, TM; Dwyer, PN, 1989)
"The efficacy of various dosage schedules of netilmicin against Pseudomonas aeruginosa has been compared using an in vivo model (normal and granulocytopenic mice)."1.27[Bolus injection, short infusion or intravenous drip of aminoglycoside antibiotics? In vivo study with netilmicin and Pseudomonas aeruginosa]. ( Brugger, HP; Feller-Segessenmann, C; Gerber, AU, 1983)
"The influence of dosing intervals on the activity of gentamicin and ticarcillin against Pseudomonas aeruginosa was studied in vivo."1.27Impact of dosing intervals on activity of gentamicin and ticarcillin against Pseudomonas aeruginosa in granulocytopenic mice. ( Brandel, J; Brugger, HP; Craig, WA; Feller, C; Gerber, AU; Vastola, AP, 1983)
"Gentamicin treatment is effective in eliminating bacteria in this model and immunization has no additional benefit."1.27Pulmonary clearance of Pseudomonas aeruginosa in neutropenic mice. Effects of systemic immunization. ( Dunn, MM; Kamp, DW, 1987)
" The effect of such dosing on bacterial time-kill curves and on survival was compared with the effect of identical amounts of drug given as a single-bolus injection."1.27Antibiotic therapy of infections due to Pseudomonas aeruginosa in normal and granulocytopenic mice: comparison of murine and human pharmacokinetics. ( Brugger, HP; Feller, C; Gerber, AU; Stalder, B; Stritzko, T, 1986)
"Gentamicin in combination with cephalothin (Gent-Ceph) or with chloramphenicol (Gent-Chloro) was utilized in the treatment of 55 infections occurring in 49 cancer patients."1.26Therapy of infections in neutropenic patients: results with gentamicin in combination with cephalothin or chloramphenicol. ( Bodey, GP; Burgess, MA; Rodriguez, V; Valdivieso, M, 1976)
"Gentamicin was at least as effective as carbenicillin regardless of inoculum size or duration of therapy."1.26Therapy of neutropenic rats infected with Pseudomonas aeruginosa. ( Lumish, RM; Norden, CW, 1976)
"Gentamicin was the single most useful antibiotic, and the infection was controlled largely with gentamicin and one other antibiotic, most often carbenicillin."1.25Septicaemia in the neutropenic patient. ( Atkinson, K; Kay, HE; McElwain, TJ, 1974)

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-199086 (94.51)18.7374
1990's4 (4.40)18.2507
2000's1 (1.10)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Pauw, BE1
Kauw, F1
Muytjens, H1
Williams, KJ1
Bothof, T1
Ramphal, R2
Kramer, BS2
Rand, KH2
Weiner, RS1
Shands, JW1
Henry, SA1
Brugger, HP3
Gerber, AU5
Feller-Segessenmann, C1
Meuret, G1
Roux, A1
Heim, ME1
Westerhausen, M1
Sluchenkova, LD1
Finogenova, NA1
Andreeva, SM1
Mamedova, EA1
Halpern, J1
Catane, R1
Sacks, T1
Fuks, Z1
Haibach, H1
Yesus, YW1
Doggett, JJ1
Wingard, JR1
Dick, JD1
Merz, WG1
Sandford, GR1
Saral, R1
Burns, WH1
Craig, WA2
Feller, C2
Vastola, AP1
Brandel, J1
Siegenthaler, W1
Fuchs, P1
Lüthy, R1
Bacigalupo, A1
Van Lint, MT1
Volta, C1
Grazi, G1
Soro, O1
Podestà, M1
Frassoni, F1
Marmont, A1
Malarme, M1
Meunier-Carpentier, F1
Klastersky, J4
Magliulo, E1
Piantieri, G1
Cafarelli, A1
Cruciani, M1
Pizzo, PA3
Robichaud, KJ2
Gill, FA2
Witebsky, FG2
Young, LS1
Meyer-Dudnik, PV1
Hindler, J1
Martin, WJ1
Matsumoto, Y1
Katoh, Y1
Higami, M1
Skiest, DJ1
King, ME1
Greter, U1
Segessenmann, C1
Kozak, S1
Alter, P1
Schaefer, JR1
Maisch, B1
Fortuny, IE1
Hadlock, DC1
Kennedy, BJ1
McCullough, JJ1
Hahn, DM4
Schimpff, SC10
Fortner, CL4
Smyth, AC1
Young, VM7
Wiernik, PH7
Pietschmann, H1
Wolk, JA1
Stuart, MJ1
Stockman, JA1
Oski, FA1
Björnsson, S1
Preisler, H1
Henderson, ES2
Hopefl, AW1
Love, LJ2
Standiford, HC2
Bender, JF2
Levine, AS1
Deisseroth, AB1
Glaubiger, DL1
Maclowry, JD1
Magrath, IT1
Poplack, DG1
Simon, RM1
Gaya, H5
Grove, WR1
Baranov, AE1
Shishkova, TV1
Pozdniakova, VP1
Bodunkova, LE1
Nadezhina, NM1
Flandrois, JP1
Fière, D3
Martin, C1
Bonnet, P1
Gurwith, M1
Brunton, JL1
Lank, B1
Ronald, AR1
Harding, GK1
McCullough, DW1
Abt, C1
Dietrich, M1
Niethammer, D1
Arnold, R1
Pflieger, H1
Töllner, U1
Vanek, E1
Kubanek, B1
Kleihauer, E1
Heimpel, H1
Tattersall, MH4
Widmaier, S1
Nagel, G1
Valdivieso, M1
Bodey, GP4
Burgess, MA1
Rodriguez, V4
Landesman, S1
Lumish, RM1
Norden, CW1
Scott, RE1
Robson, HG1
Dorn, CR1
Coffman, JR1
Schmidt, DA1
Garner, HE1
Addison, JB1
McCune, EL1
Chang, JC1
Reyes, B1
Krcméry, V1
Fuchsberger, P1
Trupl, J1
Sufliarsky, J1
Spanik, S1
Koza, I1
Kusenda, Z1
Korec, S1
Svec, J1
Durkovic, P1
Kinsey, SE1
Machin, SJ1
Goldstone, AH1
Bianco, TM1
Dwyer, PN1
Bertino, JS1
Chastagner, P1
Hartmann, O1
Tancrede, C1
Kalifa, C1
Patte, C1
Flamant, F1
Lemerle, J1
Nemet, D1
Kalenic, S1
Badanjak, A1
Bogdanic, V1
Davila, N1
Francetić, I1
Labar, B1
Fink, FM1
Frischhut-Schiffer, EM1
Ausserer, B1
Allerberger, F1
Guggenbichler, JP1
Boughton, BJ1
Harris, RI1
Brown, RM1
Webberley, J1
Baglin, TP1
Jackson, N1
Girling, AJ1
Dunn, MM1
Kamp, DW1
O'Brien, AJ1
Fenelon, LE1
O'Dwyer, R1
McCann, SR1
Daly, PA1
Rawlinson, W1
Sorrell, T1
Munro, R1
Granowetter, L1
Wells, H1
Lange, BJ1
Trautmann, M1
Brückner, O1
Marre, R1
Hahn, H1
Stritzko, T1
Stalder, B1
Hathorn, JW1
Hiemenz, J1
Browne, M1
Commers, J1
Cotton, D1
Gress, J1
Longo, D1
Marshall, D1
McKnight, J1
González, M1
Clavell, LA1
Zinner, SH2
Dudley, M1
Blaser, J1
Guyotat, D1
Plonton, C1
Tancrède, CH1
Andremont, AO1
Spiers, AS4
Darrell, JH1
Helm, E1
Stille, W2
Greene, WH3
Moody, M1
Schimpff, S2
Dale, DC1
Reynolds, HY1
Pennington, JE1
Elin, RJ1
Pitts, TW1
Graw, RG1
Assmann, D1
Gläser, U1
Preisler, HD1
Goldstein, IM1
VanOmmen, RA1
Hutchinson, RM1
Chojnacki, J1
Zydowicz, L1
Middleman, E2
Umsawadi, T1
Sande, MA1
Overton, JW1
Jedrzejczak, WW1
Czarnecki, C1
Levi, JA1
Vincent, PC1
Jennis, F1
Lind, DE1
Gunz, FW1
Burgess, M1
Bussien, R1
Atkinson, K1
Kay, HE1
McElwain, TJ1
Satterlee, W1
Serpick, A1
Osler, DC1
Rutsky, EA1
Walbaum, R1
Scharfman, W1
Morel, P1
Umsawasdi, T1
Jacoby, GA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
ANTIVORIFUNGOL:Strategy of Antifungal Use in Oncohematological Neutropenic Patients. Use of Voriconazole as Early Treatment.[NCT00386802]Phase 4115 participants (Anticipated)Interventional2006-08-31Completed
An Open Intravenous Multiple Dose, Multi-Center Study to Investigate the Pharmacokinetics, Safety and Toleration of Voriconazole in Children Aged 2-12 Years Who Require Treatment for the Prevention of Systemic Fungal Infection[NCT00005912]Phase 148 participants Interventional2000-06-30Completed
Phase I Study of the Safety, Tolerance, and Pharmacokinetics of FK463 in Immunocompromised Children With Fever and Neutropenia[NCT00001790]Phase 1120 participants Interventional1998-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for gentamicin and Agranulocytosis

ArticleYear
Symposium on infectious complications of neoplastic disease (Part II). Chemoprophylaxis of bacterial infections in granulocytopenic patients.
    The American journal of medicine, 1984, Volume: 76, Issue:4

    Topics: Acute Disease; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topi

1984
Empiric therapy of febrile granulocytopenic patients.
    American journal of hospital pharmacy, 1979, Volume: 36, Issue:2

    Topics: Agranulocytosis; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Blood Transfusion; Cephalosp

1979
The use of synergistic combinations of antibiotics in patients with haematological diseases.
    Clinics in haematology, 1976, Volume: 5, Issue:2

    Topics: Agranulocytosis; Ampicillin; Animals; Anti-Bacterial Agents; Bacterial Infections; Blood Bactericida

1976
[Management of infections in neutropenia].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1974, Nov-01, Volume: 27, Issue:21

    Topics: Agranulocytosis; Bacterial Infections; Carbenicillin; Cross Infection; Gentamicins; Humans; Immunity

1974

Trials

28 trials available for gentamicin and Agranulocytosis

ArticleYear
Randomized study of ceftazidime versus gentamicin plus cefotaxime for infections in severe granulocytopenic patients.
    The Journal of antimicrobial chemotherapy, 1983, Volume: 12 Suppl A

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Cefotaxime; Ceftazidime; Cephalospor

1983
Early results of a comparative trial of ceftazidime versus cephalothin, carbenicillin and gentamicin in the treatment of febrile granulocytopenic patients.
    The Journal of antimicrobial chemotherapy, 1983, Volume: 12 Suppl A

    Topics: Adult; Aged; Agranulocytosis; Bacterial Infections; Carbenicillin; Ceftazidime; Cephalosporins; Ceph

1983
Symposium on infectious complications of neoplastic disease (Part II). Chemoprophylaxis of bacterial infections in granulocytopenic patients.
    The American journal of medicine, 1984, Volume: 76, Issue:4

    Topics: Acute Disease; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topi

1984
[Treatment of severe febrile neutropenia (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Dec-19, Volume: 105, Issue:51

    Topics: Agranulocytosis; Carbenicillin; Drug Evaluation; Drug Therapy, Combination; Fever; Gentamicins; Huma

1980
Tobramycin versus gentamicin, in combination with cephalotin and carbenecillin, in patients undergoing bone marrow transplantation.
    Tumori, 1981, Dec-31, Volume: 67, Issue:6

    Topics: Adolescent; Adult; Agranulocytosis; Anti-Bacterial Agents; Bone Marrow Transplantation; Carbenicilli

1981
Vancomycin plus gentamicin and cotrimoxazole for prevention of infections in neutropenic cancer patients (a comparative, placebo-controlled pilot study).
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:12

    Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Clinical

1981
Aminoglycosides in the treatment of bacteraemic infections in the immuno-comprised host.
    The Journal of antimicrobial chemotherapy, 1981, Volume: 8 Suppl A

    Topics: Agranulocytosis; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Drug Therapy, Combination; Gentam

1981
Letter: Granulocyte tranfusions in acute leukeamia.
    Lancet (London, England), 1975, Mar-08, Volume: 1, Issue:7906

    Topics: Adult; Agranulocytosis; Blood Transfusion; Carbenicillin; Cephalothin; Drug Therapy, Combination; Fe

1975
Therapy of infection in patients with granulocytopenia.
    The Medical clinics of North America, 1977, Volume: 61, Issue:5

    Topics: Agranulocytosis; Amikacin; Anti-Bacterial Agents; Blood Transfusion; Carbenicillin; Cephalothin; Cli

1977
A study of antibiotic therapy in fever of unknown origin in neutropenic cancer patients.
    Medical and pediatric oncology, 1977, Volume: 3, Issue:4

    Topics: Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Carbenicillin; Cephalothin; Chloramphenicol; Cl

1977
Randomized trial of empiric antibiotic therapy with ticarcillin in combination with gentamicin, amikacin or netilmicin in febrile patients with granulocytopenia and cancer.
    The American journal of medicine, 1979, Volume: 66, Issue:4

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Bacterial Infections; Clinical Trials as Topic;

1979
Duration of empiric antibiotic therapy in granulocytopenic patients with cancer.
    The American journal of medicine, 1979, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Agranulocytosis; Carbenicillin; Cephalothin; Child; Child, Preschool; Clinical Tr

1979
Empirical therapy in febrile granulocytopenic patients.
    European journal of cancer, 1979, Volume: 15 Suppl

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Blo

1979
Granulocytopenia in hospitalized patients. II. A prospective comparison of two antibiotic regimens in the empiric therapy of febrile patients.
    The American journal of medicine, 1978, Volume: 64, Issue:1

    Topics: Adolescent; Agranulocytosis; Carbenicillin; Cephalothin; Child; Child, Preschool; Drug Therapy, Comb

1978
Protocol for an international prospective trial of initial therapy regimens in neutropenic patients with malignant disease.
    European journal of cancer, 1975, Volume: 11suppl

    Topics: Agranulocytosis; Bacterial Infections; Blood; Carbenicillin; Cephalothin; Clinical Trials as Topic;

1975
Prospective randomly controlled trial of three antibiotic combinations for empirical therapy of suspected sepsis in neutropenic cancer patients.
    European journal of cancer, 1975, Volume: 11suppl

    Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Cephalothin; Clinical Trials as Topic;

1975
Ticarcillin in combination with cephalothin or gentamicin as empiric antibiotic therapy in granulocytopenic cancer patients.
    Antimicrobial agents and chemotherapy, 1976, Volume: 10, Issue:5

    Topics: Adult; Agranulocytosis; Bacterial Infections; Cephalothin; Clinical Trials as Topic; Drug Evaluation

1976
Ciprofloxacin plus vancomycin versus ceftazidime plus gentamicin in the treatment of pneumonia in granulocytopenic patients with or without venous catheters. Short communication.
    Chemotherapy, 1992, Volume: 38, Issue:4

    Topics: Adult; Agranulocytosis; Bronchopneumonia; Catheterization; Ceftazidime; Ciprofloxacin; Drug Therapy,

1992
Ceftazidime monotherapy is as effective as ceftazidime combined with gentamicin in the treatment of febrile neutropenic patients.
    The Journal of hospital infection, 1990, Volume: 15 Suppl A

    Topics: Agranulocytosis; Anti-Bacterial Agents; Cause of Death; Ceftazidime; Drug Therapy, Combination; Fema

1990
Prevention of gram-negative bacterial infection in granulocytopenic patients: a randomized study comparing oral norfloxacin with gentamycin.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 3

    Topics: Administration, Oral; Adolescent; Adult; Agranulocytosis; Bacterial Infections; Gentamicins; Gram-Ne

1989
Gentamicin and low dose piperacillin in febrile neutropenic patients.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 24, Issue:1

    Topics: Adult; Agranulocytosis; Bacterial Infections; Fever; Gentamicins; Humans; Injections, Intravenous; L

1989
A comparative study of latamoxef disodium and gentamicin versus piperacillin and gentamicin in febrile granulocytopenic patients.
    The British journal of clinical practice, 1988, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Drug Therapy, Combination; Female; Fever; Gentamicins; Hum

1988
Ceftazidime with or without vancomycin vs. cephalothin, carbenicillin and gentamicin as the initial therapy of the febrile neutropenic pediatric cancer patient.
    The Pediatric infectious disease journal, 1988, Volume: 7, Issue:3

    Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Carbenicillin; Ceftazidime; Cephalothi

1988
A randomized trial comparing ceftazidime alone with combination antibiotic therapy in cancer patients with fever and neutropenia.
    The New England journal of medicine, 1986, Aug-28, Volume: 315, Issue:9

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Carbenicillin

1986
Randomized comparison between two ceftazidime-containing regimens and cephalothin-gentamicin-carbenicillin in febrile granulocytopenic cancer patients.
    Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:1

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents; Bacterial Infections; Ceftazidime; Cephalothin;

1986
A randomized trial of oral vancomycin in neutropenic patients.
    Progress in clinical and biological research, 1985, Volume: 181

    Topics: Administration, Oral; Adolescent; Adult; Aged; Agranulocytosis; Antineoplastic Agents; Clinical Tria

1985
Review of amikacin usage in the EORTC trials.
    The American journal of medicine, 1985, Jul-15, Volume: 79, Issue:1A

    Topics: Agranulocytosis; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topic; Dr

1985
Infections in cancer patients. Results with gentamicin sulfate therapy.
    Cancer, 1972, Volume: 29, Issue:6

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Blood Urea Nitrogen; Cellulitis; Child; Clinical Trials as

1972

Other Studies

60 other studies available for gentamicin and Agranulocytosis

ArticleYear
[Bolus injection, short infusion or intravenous drip of aminoglycoside antibiotics? In vivo study with netilmicin and Pseudomonas aeruginosa].
    Schweizerische medizinische Wochenschrift, 1983, Dec-10, Volume: 113, Issue:49

    Topics: Agranulocytosis; Animals; Delayed-Action Preparations; Disease Models, Animal; Gentamicins; Infusion

1983
[Drug-induced disease--Lyell's syndrome and agranulocytosis--in a young child].
    Pediatriia, 1984, Issue:7

    Topics: Agranulocytosis; Child, Preschool; Female; Gentamicins; Humans; Prednisolone; Stevens-Johnson Syndro

1984
Treatment of febrile granuloycytopenic cancer patients receiving antineoplastic therapy with a combination of carbenicillin, cefazolin and gentamicin.
    Journal of medicine, 1983, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Antineoplastic Combined Chemotherap

1983
Pentazocine-induced agranulocytosis.
    Canadian Medical Association journal, 1984, May-01, Volume: 130, Issue:9

    Topics: Agranulocytosis; Cephalothin; Gentamicins; Humans; Leukocyte Count; Male; Middle Aged; Neutrophils;

1984
Differences in virulence of clinical isolates of Candida tropicalis and Candida albicans in mice.
    Infection and immunity, 1982, Volume: 37, Issue:2

    Topics: Agranulocytosis; Animals; Candida albicans; Candidiasis; Cytarabine; Female; Gentamicins; Humans; In

1982
Aminoglycoside-selected subpopulations of Pseudomonas aeruginosa: characterization and virulence in normal and leukopenic mice.
    The Journal of laboratory and clinical medicine, 1982, Volume: 100, Issue:5

    Topics: Agranulocytosis; Aminoglycosides; Animals; Anti-Bacterial Agents; Drug Resistance, Microbial; Female

1982
Impact of dosing intervals on activity of gentamicin and ticarcillin against Pseudomonas aeruginosa in granulocytopenic mice.
    The Journal of infectious diseases, 1983, Volume: 147, Issue:5

    Topics: Agranulocytosis; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Thera

1983
[Prevention of bacterial infections].
    Der Internist, 1981, Volume: 22, Issue:2

    Topics: Agranulocytosis; Amoxicillin; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Endocarditis;

1981
Therapy of Klebsiella pneumoniae septicaemia in neutropenic rats.
    Pharmatherapeutica, 1982, Volume: 3, Issue:2

    Topics: Agranulocytosis; Amikacin; Animals; Anti-Bacterial Agents; Female; Gentamicins; Klebsiella Infection

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
    The American journal of medicine, 1982, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Agranulocytosis; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacter

1982
[A case of common variable immunodeficiency associated with marked granulocytopenia (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1981, Volume: 22, Issue:9

    Topics: Adolescent; Agammaglobulinemia; Agranulocytosis; Anti-Bacterial Agents; Gentamicins; Humans; Male; S

1981
Granulocytopenia secondary to acute infection with the human immunodeficiency virus.
    The Journal of infection, 1994, Volume: 28, Issue:3

    Topics: Acute Disease; Adult; Agranulocytosis; Clavulanic Acids; Diagnosis, Differential; Drug Therapy, Comb

1994
The impact of the pre-treatment interval on antimicrobial efficacy in a biological model.
    The Journal of antimicrobial chemotherapy, 1993, Volume: 31 Suppl D

    Topics: Agranulocytosis; Animals; Anti-Bacterial Agents; Ceftazidime; Female; Gentamicins; Mice; Mice, Inbre

1993
[Impediment of cellular immune response under treatment with ticlopidine in a patient with Staphylococcus aureus endocarditis].
    Zeitschrift fur Kardiologie, 2000, Volume: 89, Issue:8

    Topics: Agranulocytosis; Angioplasty, Balloon, Coronary; Anti-Bacterial Agents; Clarithromycin; Coronary Dis

2000
Infection in acute leukemia patients receiving oral nonabsorable antibiotics.
    Antimicrobial agents and chemotherapy, 1978, Volume: 13, Issue:6

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents

1978
[Treatment of infection in bone-marrow insufficiency].
    Hamatologie und Bluttransfusion, 1975, Volume: 16

    Topics: Agranulocytosis; Ampicillin; Anemia, Aplastic; Bacterial Infections; Bone Marrow Diseases; Carbenici

1975
Neutropenia, fever, and infection in children with acute lymphocytic leukemia.
    American journal of diseases of children (1960), 1977, Volume: 131, Issue:2

    Topics: Agranulocytosis; Asparaginase; Child; Fever; Gentamicins; Granulocytes; Humans; Infections; Leukemia

1977
Comparative auditory toxicity of aminoglycoside antibiotics in leukopenic patients.
    American journal of hospital pharmacy, 1979, Volume: 36, Issue:8

    Topics: Agranulocytosis; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Audiometry; Drug Therapy, Combina

1979
[Gentamycin sulfate effectiveness and tolerance in patients with myelotoxic agranulocytosis].
    Antibiotiki, 1979, Volume: 24, Issue:8

    Topics: Agranulocytosis; Drug Evaluation; Drug Therapy, Combination; Drug Tolerance; Evaluation Studies as T

1979
Possible high dosage gentamycin therapy in infected neutropenic patients.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1977, Volume: 27, Issue:9-10

    Topics: Agranulocytosis; Ampicillin; Drug Therapy, Combination; Gentamicins; Humans; Infections; Neutropenia

1977
[Acute drug-induced agranulocytosis: comparison between openward treatment and antimicrobial decontamination in a plastic isolation bed system (retrospective study of 30 cases) (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1978, Jan-20, Volume: 103, Issue:3

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Blood Transfusion; Carbenicillin; Ch

1978
Therapy of infections in neutropenic patients: results with gentamicin in combination with cephalothin or chloramphenicol.
    Medical and pediatric oncology, 1976, Volume: 2, Issue:1

    Topics: Agranulocytosis; Bacterial Infections; Cephalothin; Chloramphenicol; Drug Therapy, Combination; Ente

1976
Therapy of neutropenic rats infected with Pseudomonas aeruginosa.
    The Journal of infectious diseases, 1976, Volume: 133, Issue:5

    Topics: Agranulocytosis; Animals; Blood; Carbenicillin; Female; Gentamicins; Microbial Sensitivity Tests; Ne

1976
Synergistic activity of carbenicillin and gentamicin in experimental Pseudomonas bacteremia in neutropenic rats.
    Antimicrobial agents and chemotherapy, 1976, Volume: 10, Issue:4

    Topics: Agranulocytosis; Animals; Carbenicillin; Drug Synergism; Female; Gentamicins; Neutropenia; Pseudomon

1976
Neutropenia and salmonellosis in hospitalized horses.
    Journal of the American Veterinary Medical Association, 1975, Jan-01, Volume: 166, Issue:1

    Topics: Agranulocytosis; Animals; Chloramphenicol; Colitis; Feces; Female; Gentamicins; Horse Diseases; Hors

1975
Agranulocytosis associated with gentamicin.
    JAMA, 1975, Jun-16, Volume: 232, Issue:11

    Topics: Aged; Agranulocytosis; Bone Marrow Examination; Gentamicins; Humans; Injections, Intramuscular; Kleb

1975
Gentamicin pharmacokinetics, nephrotoxicity, and prediction of mortality in febrile neutropenic patients.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:11

    Topics: Agranulocytosis; Creatinine; Female; Fever; Gentamicins; Half-Life; Humans; Kidney Diseases; Male; M

1989
Role of parenteral antibiotherapy in gastrointestinal tract flora suppression. A study in children treated with high-dose chemotherapy and autologous bone marrow transplantation.
    Bone marrow transplantation, 1989, Volume: 4, Issue:4

    Topics: Adolescent; Agranulocytosis; Bone Marrow Transplantation; Cefotaxime; Child; Child, Preschool; Diges

1989
[Empirical antimicrobial therapy of infection and fever episodes in children and adolescents with neutropenia caused by cytotoxic chemotherapy].
    Padiatrie und Padologie, 1989, Volume: 24, Issue:1

    Topics: Adolescent; Agranulocytosis; Antineoplastic Agents; Cefamandole; Cefotaxime; Child; Child, Preschool

1989
Pulmonary clearance of Pseudomonas aeruginosa in neutropenic mice. Effects of systemic immunization.
    The American review of respiratory disease, 1987, Volume: 135, Issue:6

    Topics: Agranulocytosis; Animals; Antibodies, Anti-Idiotypic; Gentamicins; Immunization, Passive; Immunoglob

1987
Bacteremia in neutropenic patients at a major teaching hospital--1981 to 1987.
    Australian and New Zealand journal of medicine, 1988, Volume: 18, Issue:6

    Topics: Agranulocytosis; Amikacin; Australia; Cefotaxime; Drug Therapy, Combination; Gentamicins; Hospitals,

1988
Comparative efficacy of ciprofloxacin, ceftazidime and gentamicin, given alone or in combination, in a model of experimental septicemia due to Klebsiella pneumoniae in neutropenic mice.
    Infection, 1988, Volume: 16, Issue:1

    Topics: Agranulocytosis; Animals; Ceftazidime; Ciprofloxacin; Disease Models, Animal; Drug Therapy, Combinat

1988
Antibiotic therapy of infections due to Pseudomonas aeruginosa in normal and granulocytopenic mice: comparison of murine and human pharmacokinetics.
    The Journal of infectious diseases, 1986, Volume: 153, Issue:1

    Topics: Agranulocytosis; Aminoglycosides; Animals; Anti-Bacterial Agents; Ceftazidime; Ceftriaxone; Female;

1986
Piperacillin and gentamicin as non toxic empirical therapy in pediatric patients with fever and neutropenia.
    Puerto Rico health sciences journal, 1987, Volume: 6, Issue:1

    Topics: Adolescent; Agranulocytosis; Bacterial Infections; Child; Child, Preschool; Drug Administration Sche

1987
In vitro models for the study of combination antibiotic therapy in neutropenic patients.
    The American journal of medicine, 1986, Jun-30, Volume: 80, Issue:6B

    Topics: Agranulocytosis; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Azlocillin; Bacterial Infections;

1986
Forecast of antibiotic susceptibility of translocating strains of enterobacteria and pseudomonas in leukemic neutropenic patients.
    Progress in clinical and biological research, 1985, Volume: 181

    Topics: Agranulocytosis; Amikacin; Ampicillin; Anti-Bacterial Agents; Cefotaxime; Enterobacteriaceae; Feces;

1985
Initial therapy with combination of five antibiotics in febrile patients with leukaemia and neutropenia.
    Lancet (London, England), 1972, Jan-22, Volume: 1, Issue:7743

    Topics: Administration, Oral; Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Bacterial Infections

1972
[Clinical and therapeutic features of pseudomonas aeruginosa septicaemia].
    Deutsche medizinische Wochenschrift (1946), 1972, Oct-20, Volume: 97, Issue:42

    Topics: Adult; Aged; Agranulocytosis; Bacteria; Carbenicillin; Catheterization; Colistin; Diabetes Complicat

1972
[Septicemic complications in leukemia and myeloic insufficiency].
    Blut, 1973, Volume: 26, Issue:6

    Topics: Agranulocytosis; Bacterial Infections; Carbenicillin; Cephalothin; Drug Synergism; Gentamicins; Huma

1973
Pseudomonas aeruginosa resistant to carbenicillin and gentamicin. Epidemiologic and clinical aspects in a cancer center.
    Annals of internal medicine, 1973, Volume: 79, Issue:5

    Topics: Agranulocytosis; Carbenicillin; Cephalothin; Drug Combinations; Enterobacteriaceae; Escherichia coli

1973
Significance of Pseudomonas aeruginosa in the patient with leukemia or lymphoma.
    The Journal of infectious diseases, 1974, Volume: 130 Suppl, Issue:0

    Topics: Agranulocytosis; Bacterial Vaccines; Brain Neoplasms; Carbenicillin; Cephalothin; Cross Infection; D

1974
Experimental pneumonia due to Pseudomonas in dogs: controlled trial of granulocyte transfusion therapy.
    The Journal of infectious diseases, 1974, Volume: 130 Suppl, Issue:0

    Topics: Agranulocytosis; Animals; Blood Transfusion; Disease Models, Animal; Dogs; Gentamicins; Granulocytes

1974
Indications for systemic antibiotic prophylaxis in neutropenic patients.
    British medical journal, 1974, Nov-23, Volume: 4, Issue:5942

    Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Biguanides; Blood Cell Count; Carbenicillin; Cephalot

1974
Letter: Pseudomonas septicaemia following superficial colonization.
    British medical journal, 1974, Dec-28, Volume: 4, Issue:5947

    Topics: Adolescent; Agranulocytosis; Carbenicillin; Child; Gentamicins; Humans; Male; Neutropenia; Pseudomon

1974
[Side effects and hazards of current antibiotic- and chemotherapy].
    Zeitschrift fur arztliche Fortbildung, 1974, May-01, Volume: 68, Issue:9

    Topics: Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Bronchial Spasm; Cephalosporins; Chloramph

1974
Gastrointestinal "sterilization" in the treatment of patients with acute leukemia.
    Cancer, 1970, Volume: 26, Issue:5

    Topics: Acute Disease; Agranulocytosis; Anti-Bacterial Agents; Antineoplastic Agents; Bacitracin; Bacteriolo

1970
Untoward effects of antimicrobial agents on major organ systems.
    The Medical clinics of North America, 1974, Volume: 58, Issue:3

    Topics: Agranulocytosis; Amphotericin B; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Ataxia;

1974
Empirical antibiotic therapy in febrile patients with neutropenia and malignant disease.
    European journal of cancer, 1973, Volume: 9, Issue:6

    Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Carbenicillin; Cephalothin; Clindamyci

1973
Pseudomonas septicemia: incidence, epidemiology, prevention and therapy in patients with advanced cancer.
    European journal of cancer, 1973, Volume: 9, Issue:6

    Topics: Agranulocytosis; Carbenicillin; Cephalothin; Enterococcus faecalis; Escherichia coli; Gentamicins; H

1973
[Case of acute agranulocytosis following treatment with gentamicin].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1974, Dec-30, Volume: 29, Issue:52

    Topics: Acute Disease; Agranulocytosis; Bronchitis; Female; Gentamicins; Humans; Middle Aged

1974
In vivo antagonism between gentamicin and chloramphenicol in neutropenic mice.
    The Journal of infectious diseases, 1973, Volume: 128, Issue:2

    Topics: Agranulocytosis; Animals; Chloramphenicol; Drug Antagonism; Gentamicins; Mice; Neutrophils; Phagocyt

1973
Prophylactic oral antibiotics in the management of acute leukaemia.
    The Medical journal of Australia, 1973, May-26, Volume: 1, Issue:21

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents

1973
Management of fever of unknown origin in patients with neoplasms and neutropenia.
    Cancer, 1973, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Carbenicillin; Cephalothin; Female;

1973
[Letter: Acute granulocytopenia after simultaneous administration of gentamicin and diazepam].
    La Nouvelle presse medicale, 1974, May-11, Volume: 3, Issue:19

    Topics: Adrenal Cortex Hormones; Aged; Agranulocytosis; Blood Cell Count; Diazepam; Drug Synergism; Female;

1974
Septicaemia in the neutropenic patient.
    British medical journal, 1974, Jul-27, Volume: 3, Issue:5925

    Topics: Adolescent; Adult; Agranulocytosis; Anemia, Aplastic; Blood Cell Count; Bone Marrow; Bone Marrow Cel

1974
Empiric therapy with carbenicillin and gentamicin for febrile patients with cancer and granulocytopenia.
    The New England journal of medicine, 1971, May-13, Volume: 284, Issue:19

    Topics: Agranulocytosis; Bacteria; Carbenicillin; Drug Synergism; Fever; Gentamicins; Humans; Infections; Kl

1971
Carbenicillin--gentamicin.
    The New England journal of medicine, 1971, Aug-12, Volume: 285, Issue:7

    Topics: Agranulocytosis; Carbenicillin; Gentamicins; Humans; Microbial Sensitivity Tests; Neoplasms; Penicil

1971
[A case of acute agranulocytosis].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1971, Volume: 16, Issue:8

    Topics: Acute Disease; Agranulocytosis; Female; Gentamicins; Humans; Infant; Male

1971
Intravenous gentamicin therapy for infections in patients with cancer.
    The Journal of infectious diseases, 1971, Volume: 124 Suppl

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Blood Urea Nitrogen; Carbenicillin;

1971
Carbenicillin and gentamicin.
    The New England journal of medicine, 1971, May-13, Volume: 284, Issue:19

    Topics: Agranulocytosis; Bacteria; Carbenicillin; Drug Synergism; Gentamicins; Humans; Leukemia; Neoplasms;

1971