gentamicin has been researched along with Acute Kidney Failure in 479 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Excerpt | Relevance | Reference |
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"International guidelines recommend high-dose cloxacillin for endocarditis or osteoarticular infections due to methicillin-susceptible staphylococci." | 8.98 | Acute kidney injury during treatment with high-dose cloxacillin: a report of 23 cases and literature review. ( Golbin, L; Lavergne, A; Polard, E; Rioux-Leclercq, N; Tattevin, P; Triquet, L; Vigneau, C, 2018) |
" This paper reports the results of studies concerning carnosine's role in kidney diseases, particularly in ischemia/reperfusion induced acute renal failure, diabetic nephropathy, gentamicin-induced nephrotoxicity and also in blood pressure regulation." | 8.88 | [Carnosine, carnosinase and kidney diseases]. ( Kiliś-Pstrusińska, K, 2012) |
"This study was designed, for the first time, to examine the possible nephroprotective effects of exogenous glutathione (EGSH) (100 mg/kg, intraperitoneally) on gentamicin-induced acute kidney injury (GM-induced AKI)." | 8.31 | Exogenous glutathione protects against gentamicin-induced acute kidney injury by inhibiting NF-κB pathway, oxidative stress, and apoptosis and regulating PCNA. ( Ahmadvand, H; Amini, A; Babaeenezhad, E; Dezfoulian, O; Fattahi, MD; Hadipour Moradi, F; Nasri, M; Rahimi Monfared, S, 2023) |
"Acute kidney injury (AKI) is a challenging side effect which may clinically impede the use of gentamicin (GM)." | 8.31 | Liraglutide ameliorates gentamicin-induced acute kidney injury in rats via PGC-1α- mediated mitochondrial biogenesis: Involvement of PKA/CREB and Notch/Hes-1 signaling pathways. ( Elkhoely, A, 2023) |
"In this investigation, a potentially novel signaling pathway in gentamicin-induced acute kidney injury-worsened by overexpression of proximal tubular enzyme, myo-inositol oxygenase (MIOX)-was elucidated." | 8.12 | Modulation of gentamicin-induced acute kidney injury by myo-inositol oxygenase via the ROS/ALOX-12/12-HETE/GPR31 signaling pathway. ( Kanwar, YS; Liao, Y; Sharma, I; Zheng, X, 2022) |
" We investigated the urinary microRNA expression profile in a gentamicin-induced acute kidney injury canine model using RNA sequencing." | 8.02 | Urinary microRNAs miR-15b and miR-30a as novel noninvasive biomarkers for gentamicin-induced acute kidney injury. ( Chen, XG; Cheng, GL; Li, B; Miao, YF; Qu, Z; Sun, B; Yang, YW; Zhou, XB, 2021) |
"To describe risk of Clostridium difficile infection associated with clindamycin and acute kidney injury associated with gentamicin during delivery hospitalizations." | 7.96 | Clindamycin, Gentamicin, and Risk of Clostridium difficile Infection and Acute Kidney Injury During Delivery Hospitalizations. ( Andrikopoulou, M; D'Alton, ME; Duffy, CR; Friedman, AM; Goffman, D; Huang, Y; Stern-Ascher, CN; Wright, JD, 2020) |
"An 83-year-old man developed acute kidney failure after intra-articular use of gentamicin sponges for a periprosthetic hip infection." | 7.96 | Acute kidney failure after intra-articular use of gentamicin sponge. ( Aarnoudse, ALHJ; Gommans, EPAT; Grouls, RJE; van der Linden, CMJ; van Erp-van Boekel, AAW; van Wensen, RJA, 2020) |
"This retrospective observational study including patients with community-acquired sepsis or septic shock and positive blood cultures, who meet Sepsis-3 criteria, shows that the addition of one single dose of gentamicin to β-lactam treatment at admittance was associated with a decreased risk of mortality and was not associated with AKI." | 7.96 | Antibiotic treatment with one single dose of gentamicin at admittance in addition to a β-lactam antibiotic in the treatment of community-acquired bloodstream infection with sepsis. ( Fredlund, H; Källman, J; Liljedahl Prytz, K; Magnuson, A; Prag, M; Sundqvist, M, 2020) |
"A 5-year-old neutered male Labrador retriever dog was presented on referral for anuric acute kidney injury (AKI) presumed secondary to parenteral gentamicin administration." | 7.91 | Cochleotoxicity and acute kidney injury secondary to parenteral gentamicin administration in a dog. ( Buckley, G; Carrera-Justiz, S; Fisk, A; Londoño, L, 2019) |
"Estrogen/estrogen receptors have a protective impact on gentamicin-induced acute kidney injury." | 7.91 | The protective role of estrogen and its receptors in gentamicin-induced acute kidney injury in rats. ( Abd El-Lateef, SM; El-Sayed, EM; Mansour, AM; Salama, SA, 2019) |
"Birth weight, the 10-minute Apgar score and gentamicin were particularly associated with acute kidney injuries in our cohort." | 7.91 | Birth weight, Apgar scores and gentamicin were associated with acute kidney injuries in VLBW neonates requiring treatment for patent ductus arteriosus. ( Aygün, A; Ebrahimi-Fakhari, D; Gortner, L; Meyer, S; Poryo, M; Wagenpfeil, G; Wissing, A; Zemlin, M, 2019) |
"To identify and characterize rates of acute kidney injury (AKI) in urologic prosthetic surgery, both before and after the implementation of weight-based gentamicin dosing." | 7.91 | Potential Association of Weight-Based Gentamicin with Increased Acute Kidney Injury in Urologic Prosthetic Surgery. ( Anele, UA; Klausner, AP; Krzastek, SC; Moore, RH; Roseman, JT, 2019) |
"To evaluate the effects of moderate aerobic exercise on the recovery phase of acute kidney injury induced by gentamicin in rats." | 7.85 | Moderate aerobic exercise on the recovery phase of gentamicin-induced acute kidney injury in rats. ( Higa, EM; Nascimento, MA; Nogueira, GB; Oliveira, CS; Punaro, GR; Rodrigues, AM, 2017) |
" To further understand the sensibility and reliability of miRNA measurements in urine sample for predicting drug-induced early nephrotoxicity, a global urinary miRNA expression analysis was performed in the rodent models with gentamicin-induced acute kidney injury (AKI)." | 7.83 | Identification of urinary microRNA biomarkers for detection of gentamicin-induced acute kidney injury in rats. ( Huo, Y; Li, B; Lin, Z; Qu, Z; Wang, J; Wang, X; Zhou, X; Zhu, C, 2016) |
"Acute kidney injury was induced in male rats with 100 mg/kg of gentamicin for six consecutive days intraperitoneally." | 7.83 | Effect of Different Times of Intraperitoneal Injections of Human Bone Marrow Mesenchymal Stem Cell Conditioned Medium on Gentamicin-Induced Acute Kidney Injury. ( Abedi, A; Azarnia, M; Foroutan, T; Golestani, S; Jamali Zahvarehy, M, 2016) |
"Objective To explore the role of the anti-inflammatory cytokine C1q/tumor necrosis factor related protein 6 (CTRP6) in gentamicin-induced acute kidney injury in rats." | 7.83 | [C1q/tumor necrosis factor related protein 6 (CTRP6) is involved in gentamicin-induced acute kidney injury in rats]. ( Feng, S; Li, R; Tian, X; Wang, H; Yang, X; Yu, Y; Zhou, M, 2016) |
"Gentamicin may cause acute kidney injury." | 7.81 | Rapamycin protects against gentamicin-induced acute kidney injury via autophagy in mini-pig models. ( Bai, XY; Cai, G; Chen, X; Cui, J; Ding, R; Hong, Q; Sun, X, 2015) |
"Uncertainty exists regarding the role of synergistic gentamicin for uncomplicated Enterococcus faecalis bacteremia in children." | 7.81 | Low-dose Gentamicin for Uncomplicated Enterococcus faecalis Bacteremia May be Nephrotoxic in Children. ( Brady, TM; Cosgrove, SE; Hsu, AJ; Ibrahim, SL; Tamma, PD; Zhang, L, 2015) |
" To explore the role of Tbx1 in acute kidney injury (AKI) and the underlying mechanism, we detected the expression of Tbx1 and components of transforming growth factor-beta (TGF-β) signaling pathways including TGF-β, phosphorylated Smad2/3 (p-Smad2/3) and phosphorylated Smad1/5/8 (p-Smad1/5/8) in kidney tissues derived from a rat model for AKI induced by gentamicin (GM)." | 7.80 | Increased Tbx1 expression may play a role via TGFβ-Smad2/3 signaling pathway in acute kidney injury induced by gentamicin. ( Huang, Y; Jiang, H; Li, L; Li, Y; Li-Ling, J; Niu, Z; Qiu, G; Sun, K, 2014) |
"A sensitive urinary biomarker for acute kidney injury (AKI) was investigated in beagle dogs with nephrotoxicity induced by gentamicin." | 7.79 | Neutrophil gelatinase-associated lipocalin, a sensitive urinary biomarker of acute kidney injury in dogs receiving gentamicin. ( Kai, K; Kinoshita, J; Takasaki, W; Teranishi, M; Yamaguchi, T; Yoshimatsu, Y, 2013) |
"This study evaluated the effects of bone marrow-derived mesenchymal stem cells (BMSCs) or their conditioned medium (CM) on the repair and prevention of Acute Kidney Injury (AKI) induced by gentamicin (G)." | 7.78 | Bone marrow-derived mesenchymal stem cells repaired but did not prevent gentamicin-induced acute kidney injury through paracrine effects in rats. ( Borges, AA; Borges, FT; Reis, LA; Schor, N; Simões, MJ; Sinigaglia-Coimbra, R, 2012) |
"The objective of the present prospective pharmacokinetic study was to describe the variability of plasma gentamicin concentrations in critically ill patients with acute kidney injury (AKI) necessitating extended daily diafiltration (EDD-f) using a population pharmacokinetic model and to subsequently perform Monte Carlo dosing simulations to determine which dose regimen achieves the pharmacodynamic targets the most consistently." | 7.76 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. ( Field, J; Kirkpatrick, CM; Lipman, J; Roberts, JA; Tallot, M; Visser, A; Whitbread, R, 2010) |
"Gentamicin is often used to treat infective endocarditis (IE)." | 7.75 | Severity of gentamicin's nephrotoxic effect on patients with infective endocarditis: a prospective observational cohort study of 373 patients. ( Bruun, NE; Buchholtz, K; Hassager, C; Larsen, CT, 2009) |
"The incidence of gentamicin-associated acute kidney injury (AKI) as defined by the RIFLE criteria is unknown." | 7.75 | Gentamicin-associated acute kidney injury. ( Fluck, RJ; Kolhe, NV; Selby, NM; Shaw, S; Woodier, N, 2009) |
" After 14 years of anorexia nervosa, the patient was treated for pneumonia with gentamicin at doses of 2 x 80 mg/24 h." | 7.73 | Regression of long standing anorexia nervosa following acute renal failure caused by gentamicin intoxication. ( Chodorowski, Z; Rutkowski, B; Rutkowski, P; Sein Anand, J, 2005) |
"Because rats with streptozotocin-induced diabetes mellitus (DM) have a high solute diuresis (glycosuria of 10 to 12 g/day), we have suggested that this may in part be responsible for their resistance to gentamicin-induced acute renal failure (ARF)." | 7.67 | Phlorizin-induced glycosuria does not prevent gentamicin nephrotoxicity in rats. ( Alpert, HC; Gouvea, WL; Kelley, J; Pardo, V; Vaamonde, CA, 1989) |
"This study describes an experimental model for the investigation of nephrotoxicity in which the aminoglycoside, gentamicin, is given after unilateral ureteral obstruction is produced." | 7.66 | Experimental evidence of increased ipsilateral gentamicin nephrotoxicity after unilateral ureteral obstruction. ( Karafin, L; Kendall, AR; Lillie, DB, 1981) |
"This paper reports our experience in monitoring gentamicin therapy during the treatment of 68 episodes of serious Gram-negative sepsis in 65 hospital patients." | 7.65 | Experience in monitoring gentamicin therapy during treatment of serious gram-negative sepsis. ( Garfield-Davies, D; Hughes, K; Noone, P; Parsons, TM; Pattison, JR; Slack, RC, 1974) |
"Sepsis and septic shock are common cause of hospitalisation in intensive care unit." | 6.48 | [An effect of continuous and intermittent renal replacement therapy on antibiotic treatment in critically ill patients with sepsis - a practice-based perspective of vancomycin and gentamycin therapies]. ( Duricová, J; Grundmann, M; Kacířová, I; Martínek, A; Petejová, N; Plášek, J; Valkovský, I; Zahálková, J, 2012) |
"Acute kidney injury is a common problem in dogs and is associated with significant morbidity and mortality." | 5.72 | Evaluation of symmetric dimethylarginine and Doppler ultrasonography in the diagnosis of gentamicin-induced acute kidney injury in dogs. ( Abdel-Raof, YM; Elgazzar, YMY; Ghanem, MM; Helal, MAY; Kandiel, MMM, 2022) |
"Gentamicin is an important broad-spectrum antibiotic; nevertheless, it exhibits serious nephrotoxic adverse effects." | 5.62 | HPLC-ESI/MS profiling, phytoconstituent isolation and evaluation of renal function, oxidative stress and inflammation in gentamicin-induced nephrotoxicity in rats of Ficus spragueana Mildbr. & Burret. ( Aboutabl, ME; Masoud, MA; Nassar, MI; Raslan, MA; Taher, RF, 2021) |
"Mice treated with gentamicin for 7 days developed AKI, and programmed cell death pathways were examined using pharmacologic inhibitors and in RIPK3-deficient mice." | 5.56 | Gentamicin-Induced Acute Kidney Injury in an Animal Model Involves Programmed Necrosis of the Collecting Duct. ( Capen, DE; Huang, H; Huang, M; Ji, H; Jin, WW; Lu, HAJ; Păunescu, TG; Xia, Y; Yuan, J, 2020) |
"Mean gentamicin dose was 4." | 5.43 | No increased risk of acute kidney injury after a single dose of gentamicin in patients with sepsis. ( Cobussen, M; de Kort, JM; Dennert, RM; Lowe, SH; Stassen, PM, 2016) |
"Gentamicin was not associated with AKI (odds ratio [OR] 0." | 5.43 | Prophylactic Gentamicin Is Not Associated with Acute Kidney Injury in Patients with Open Fractures. ( Duane, TM; Gandhi, RR; Moore, B; Putty, B; Tessier, JM, 2016) |
"Antibiotic-loaded bone cement (ALBC) spacers are the mainstay in 2-stage revision, but antibiotics (vancomycin plus aminoglycosides) may undergo systemic absorption, resulting in acute kidney injury (AKI)." | 5.41 | Nephrotoxicity Related to Antibiotic-Loaded Spacers in a 2-Stage Revision for Periprosthetic Joint Infection. ( Benito, J; Corces, A; Higuera, CA; Judd, H; Pannu, TS; Villa, JM, 2023) |
"Gentamicin was injected at a dose of 40 mg/kg body weight (the first treated group) and 80 mg/kg body weight (the second treated group) for 14 days." | 5.36 | Distribution and amount of cathepsin B in gentamicin-induced acute kidney injury in rats. ( Juntes, P; Pogacnik, M; Svara, T, 2010) |
"Acute renal failure was induced in rats by subcutaneous injection of 200 mg/kg body weight gentamicin on 3 consecutive days." | 5.26 | Gentamicin-induced acute renal failure in the rat. Effect of dehydration, DOCA-saline and furosemide. ( Brunner, FP; de Rougemont, D; Konrad, L; Oeschger, A; Thiel, G; Torhorst, J; Wenk, M; Wunderlich, P, 1981) |
"International guidelines recommend high-dose cloxacillin for endocarditis or osteoarticular infections due to methicillin-susceptible staphylococci." | 4.98 | Acute kidney injury during treatment with high-dose cloxacillin: a report of 23 cases and literature review. ( Golbin, L; Lavergne, A; Polard, E; Rioux-Leclercq, N; Tattevin, P; Triquet, L; Vigneau, C, 2018) |
" This paper reports the results of studies concerning carnosine's role in kidney diseases, particularly in ischemia/reperfusion induced acute renal failure, diabetic nephropathy, gentamicin-induced nephrotoxicity and also in blood pressure regulation." | 4.88 | [Carnosine, carnosinase and kidney diseases]. ( Kiliś-Pstrusińska, K, 2012) |
" Intravenous gentamicin is associated with increased risk of acute kidney injury, whereas intravenous tobramycin is less so." | 4.86 | Aminoglycoside use in cystic fibrosis: therapeutic strategies and toxicity. ( Prayle, A; Smyth, AR, 2010) |
" Investigators have explored the potential therapeutic role of anti-oxidants in both experimental animal models and human studies of AKI in several clinical settings, including cardiac and aortic occlusive surgeries, sepsis, drug nephrotoxicity (cisplatin and gentamicin), as well as rhabdomyolysis." | 4.84 | Antioxidants. Do they have a place in the prevention or therapy of acute kidney injury? ( Koyner, JL; Murray, PT; Sher Ali, R, 2008) |
"This study was designed, for the first time, to examine the possible nephroprotective effects of exogenous glutathione (EGSH) (100 mg/kg, intraperitoneally) on gentamicin-induced acute kidney injury (GM-induced AKI)." | 4.31 | Exogenous glutathione protects against gentamicin-induced acute kidney injury by inhibiting NF-κB pathway, oxidative stress, and apoptosis and regulating PCNA. ( Ahmadvand, H; Amini, A; Babaeenezhad, E; Dezfoulian, O; Fattahi, MD; Hadipour Moradi, F; Nasri, M; Rahimi Monfared, S, 2023) |
"The current experiment aimed to identify the possible protective role of rivastigmine (RIVA) in gentamicin (GNT)-induced acute kidney injury (AKI) in rats." | 4.31 | Rivastigmine ameliorates gentamicin experimentally induced acute renal toxicity. ( Abdelzaher, WY; AboBakr Ali, AHS; Aly Labib, DA; El-Tahawy, NFG; Mohamed, HA; Welson, NN, 2023) |
"Acute kidney injury (AKI) is a challenging side effect which may clinically impede the use of gentamicin (GM)." | 4.31 | Liraglutide ameliorates gentamicin-induced acute kidney injury in rats via PGC-1α- mediated mitochondrial biogenesis: Involvement of PKA/CREB and Notch/Hes-1 signaling pathways. ( Elkhoely, A, 2023) |
" The aims of this study were to track the 7-day time course of blood miRNAs in patients with sepsis treated with vancomycin, gentamicin, or a non-nephrotoxic antibiotic and miRNA associations with neutrophil gelatinase-associated lipokalin (NGAL), creatinine, procalcitonin, interleukin-6, and acute kidney injury (AKI) stage." | 4.12 | Expression and 7-day time course of circulating microRNAs in septic patients treated with nephrotoxic antibiotic agents. ( Bace, E; Bris, R; Kacirova, I; Kanova, M; Klementa, V; Martinek, A; Petejova, N; Pribylova, L; Sigutova, R; Stejskal, D; Svagera, Z; Zadrazil, J, 2022) |
"In this investigation, a potentially novel signaling pathway in gentamicin-induced acute kidney injury-worsened by overexpression of proximal tubular enzyme, myo-inositol oxygenase (MIOX)-was elucidated." | 4.12 | Modulation of gentamicin-induced acute kidney injury by myo-inositol oxygenase via the ROS/ALOX-12/12-HETE/GPR31 signaling pathway. ( Kanwar, YS; Liao, Y; Sharma, I; Zheng, X, 2022) |
" Necrosis, apoptosis and inflammation are commonly considered as the leading mechanism in acute kidney injury (AKI) induced by gentamicin (GEN), which is a useful antibiotic for treating the infection of Gram-negative bacterial." | 4.12 | Protective effect of inhibiting necroptosis on gentamicin-induced nephrotoxicity. ( Chen, SQ; Feng, XW; Gong, Q; Hu, BF; Li, C; Li, J; Liu, MM; Ma, WX; Meng, XM; Wang, F; Wang, JN; Wang, XF; Wen, JG; Yue, L, 2022) |
" Biochemical evaluation was carried out by assessment of body weights and by estimating renal function tests (plasma urea, plasma creatinine and plasma uric acid), tissue antioxidant enzymes (catalase, SOD) and MDA level." | 4.02 | Protective role of salicylic acid in gentamicin induced nephrotoxicity. ( Fatimah, SN; Usman, SM, 2021) |
"Acute Kidney Injury (AKI), a common disease of the urinary system, can be induced by high doses of gentamicin (GM)." | 4.02 | Oral Treatment with Angiotensin-(1-7) Attenuates the Kidney Injury Induced by Gentamicin in Wistar Rats. ( de Castro, CH; de Souza Lino Junior, R; Dos Santos, RAS; Dutra, JBR; Ferreira, PM; Pacheco, LF; Ulhoa, CJ, 2021) |
" We investigated the urinary microRNA expression profile in a gentamicin-induced acute kidney injury canine model using RNA sequencing." | 4.02 | Urinary microRNAs miR-15b and miR-30a as novel noninvasive biomarkers for gentamicin-induced acute kidney injury. ( Chen, XG; Cheng, GL; Li, B; Miao, YF; Qu, Z; Sun, B; Yang, YW; Zhou, XB, 2021) |
"To describe risk of Clostridium difficile infection associated with clindamycin and acute kidney injury associated with gentamicin during delivery hospitalizations." | 3.96 | Clindamycin, Gentamicin, and Risk of Clostridium difficile Infection and Acute Kidney Injury During Delivery Hospitalizations. ( Andrikopoulou, M; D'Alton, ME; Duffy, CR; Friedman, AM; Goffman, D; Huang, Y; Stern-Ascher, CN; Wright, JD, 2020) |
" Three models of experimental AKI were undertaken in adult male Wistar rats; renal ischemia-reperfusion injury (IRI) and gentamicin (G) and cisplatin (Cisp) nephrotoxicity." | 3.96 | Impaired Tubular Reabsorption Is the Main Mechanism Explaining Increases in Urinary NGAL Excretion Following Acute Kidney Injury in Rats. ( Blanco-Gozalo, V; Docherty, NG; López-Hernández, FJ; López-Novoa, JM; Martínez-Salgado, C; Montero-Gómez, MJ; Morales, AI; Prieto-García, L; Quiros, Y; Sancho-Martínez, SM, 2020) |
"Gentamicin is a nephrotoxic antibiotic that causes acute kidney injury (AKI) primarily by targeting the proximal tubule epithelial cell." | 3.96 | Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity. ( Borkan, SC; Campbell, JD; Feng, H; Havasi, A; Huiting, L; Igwebuike, C; Pimentel, D; Sherman, MY; Wang, Z; Yaglom, J, 2020) |
"An 83-year-old man developed acute kidney failure after intra-articular use of gentamicin sponges for a periprosthetic hip infection." | 3.96 | Acute kidney failure after intra-articular use of gentamicin sponge. ( Aarnoudse, ALHJ; Gommans, EPAT; Grouls, RJE; van der Linden, CMJ; van Erp-van Boekel, AAW; van Wensen, RJA, 2020) |
"This retrospective observational study including patients with community-acquired sepsis or septic shock and positive blood cultures, who meet Sepsis-3 criteria, shows that the addition of one single dose of gentamicin to β-lactam treatment at admittance was associated with a decreased risk of mortality and was not associated with AKI." | 3.96 | Antibiotic treatment with one single dose of gentamicin at admittance in addition to a β-lactam antibiotic in the treatment of community-acquired bloodstream infection with sepsis. ( Fredlund, H; Källman, J; Liljedahl Prytz, K; Magnuson, A; Prag, M; Sundqvist, M, 2020) |
"Although gentamicin is widely used as an antibiotic in clinical practice, it also has some side-effects, such as acute kidney injury, which is a common condition caused by the abuse of gentamicin." | 3.96 | Purified Sika deer antler protein attenuates GM-induced nephrotoxicity by activating Nrf2 pathway and inhibiting NF-κB pathway. ( Luo, J; Ruan, H; Wang, J; Wang, L; Wang, Z; Zhang, J, 2020) |
"A 5-year-old neutered male Labrador retriever dog was presented on referral for anuric acute kidney injury (AKI) presumed secondary to parenteral gentamicin administration." | 3.91 | Cochleotoxicity and acute kidney injury secondary to parenteral gentamicin administration in a dog. ( Buckley, G; Carrera-Justiz, S; Fisk, A; Londoño, L, 2019) |
"Estrogen/estrogen receptors have a protective impact on gentamicin-induced acute kidney injury." | 3.91 | The protective role of estrogen and its receptors in gentamicin-induced acute kidney injury in rats. ( Abd El-Lateef, SM; El-Sayed, EM; Mansour, AM; Salama, SA, 2019) |
"Birth weight, the 10-minute Apgar score and gentamicin were particularly associated with acute kidney injuries in our cohort." | 3.91 | Birth weight, Apgar scores and gentamicin were associated with acute kidney injuries in VLBW neonates requiring treatment for patent ductus arteriosus. ( Aygün, A; Ebrahimi-Fakhari, D; Gortner, L; Meyer, S; Poryo, M; Wagenpfeil, G; Wissing, A; Zemlin, M, 2019) |
"To identify and characterize rates of acute kidney injury (AKI) in urologic prosthetic surgery, both before and after the implementation of weight-based gentamicin dosing." | 3.91 | Potential Association of Weight-Based Gentamicin with Increased Acute Kidney Injury in Urologic Prosthetic Surgery. ( Anele, UA; Klausner, AP; Krzastek, SC; Moore, RH; Roseman, JT, 2019) |
"To determine the incidence of acute kidney injury (AKI) in aged patients receiving empiric gentamicin therapy." | 3.88 | Renal safety of short-term empiric gentamicin therapy in aged patients. ( Adler, NR; Ananda-Rajah, MR; Aung, AK; Liew, D; Sia, CS; Tong, EY; Yi-Wei, B, 2018) |
"To evaluate the risk of nonsteroidal anti-inflammatory drug (NSAID) therapy-associated acute kidney injury (AKI) among neonates diagnosed with patent ductus arteriosus (PDA) who are treated with gentamicin." | 3.85 | Risk of nonsteroidal anti-inflammatory drug-associated renal dysfunction among neonates diagnosed with patent ductus arteriosus and treated with gentamicin. ( Balch, A; Constance, JE; Korgenski, EK; Reith, D; Sherwin, CMT; Stockmann, C; Thorell, EA; Ward, RM, 2017) |
"To evaluate the effects of moderate aerobic exercise on the recovery phase of acute kidney injury induced by gentamicin in rats." | 3.85 | Moderate aerobic exercise on the recovery phase of gentamicin-induced acute kidney injury in rats. ( Higa, EM; Nascimento, MA; Nogueira, GB; Oliveira, CS; Punaro, GR; Rodrigues, AM, 2017) |
" To further understand the sensibility and reliability of miRNA measurements in urine sample for predicting drug-induced early nephrotoxicity, a global urinary miRNA expression analysis was performed in the rodent models with gentamicin-induced acute kidney injury (AKI)." | 3.83 | Identification of urinary microRNA biomarkers for detection of gentamicin-induced acute kidney injury in rats. ( Huo, Y; Li, B; Lin, Z; Qu, Z; Wang, J; Wang, X; Zhou, X; Zhu, C, 2016) |
"Evidence has shown that a prophylactic antibiotic regimen of flucloxacillin and gentamicin for orthopaedic surgery was associated with increased rates of post-operative acute kidney injury (AKI)." | 3.83 | Reduction in post-operative acute kidney injury following a change in antibiotic prophylaxis policy for orthopaedic surgery: an observational study. ( Bayne, G; Bell, S; Davey, P; Marwick, C; Nathwani, D; Patton, A; Sneddon, J; Walker, H, 2016) |
"Acute kidney injury was induced in male rats with 100 mg/kg of gentamicin for six consecutive days intraperitoneally." | 3.83 | Effect of Different Times of Intraperitoneal Injections of Human Bone Marrow Mesenchymal Stem Cell Conditioned Medium on Gentamicin-Induced Acute Kidney Injury. ( Abedi, A; Azarnia, M; Foroutan, T; Golestani, S; Jamali Zahvarehy, M, 2016) |
"Objective To explore the role of the anti-inflammatory cytokine C1q/tumor necrosis factor related protein 6 (CTRP6) in gentamicin-induced acute kidney injury in rats." | 3.83 | [C1q/tumor necrosis factor related protein 6 (CTRP6) is involved in gentamicin-induced acute kidney injury in rats]. ( Feng, S; Li, R; Tian, X; Wang, H; Yang, X; Yu, Y; Zhou, M, 2016) |
"In our study, a model of Gentamicin-induced nephrotoxicity in male Sprague Dawley rats treated for up to 7 days at 50 or 100mg/kg/day was used to monitor the expressions of novel biomarkers of renal toxicity during the progression of acute kidney injury (AKI)." | 3.83 | Evaluation of KIM-1 and NGAL as Early Indicators for Assessment of Gentamycin-Induced Nephrotoxicity In Vivo and In Vitro. ( Chen, ML; Chen, ZL; Cheng, AC; Fang, J; Geng, Y; Huang, C; Luo, QH; Tang, L, 2016) |
"This study investigates the effects of zinc in acute kidney injury induced by gentamicin (Ge)." | 3.83 | The protective effects of zinc in experimental gentamicin induced acute renal failure in rats. ( Gales, C; Mititelu-Tartau, L; Nechifor, M; Pasca, AS; Saftencu, PM; Schiriac, CE; Teslariu, O, 2016) |
"Gentamicin-induced nephrotoxicity is one of the most common causes of acute kidney injury (AKI)." | 3.81 | Protective effects of curcumin on acute gentamicin-induced nephrotoxicity in rats. ( Chen, X; He, L; Liu, F; Liu, G; Liu, H; Peng, X; Peng, Y; Tang, C; Zhu, J, 2015) |
"Gentamicin may cause acute kidney injury." | 3.81 | Rapamycin protects against gentamicin-induced acute kidney injury via autophagy in mini-pig models. ( Bai, XY; Cai, G; Chen, X; Cui, J; Ding, R; Hong, Q; Sun, X, 2015) |
"Uncertainty exists regarding the role of synergistic gentamicin for uncomplicated Enterococcus faecalis bacteremia in children." | 3.81 | Low-dose Gentamicin for Uncomplicated Enterococcus faecalis Bacteremia May be Nephrotoxic in Children. ( Brady, TM; Cosgrove, SE; Hsu, AJ; Ibrahim, SL; Tamma, PD; Zhang, L, 2015) |
"The objective of the present study was to examine the changes in the expression profile of certain genes in rat model of gentamicin-induced acute kidney injury (AKI) and to see whether time period and routes of administration affect their expression levels." | 3.81 | Transcription profile of genes affected in response to pathological changes in drug-induced rat model of acute kidney injury. ( Alam, G; Ali, A; Begum, S; Habib, R; Kabir, N; Khan, I; Salim, A; Waseem, M, 2015) |
" In this nested case-control study, independent AKI risk factors were vancomycin coadministration, high AG trough levels and heart failure." | 3.81 | Acute Kidney Injury and Renal Recovery with the Use of Aminoglycosides: A Large Retrospective Study. ( Ammann, H; Bernier-Jean, A; Bouchard, J; Brunette, V; Lavergne, V; Paquette, F; Pichette, V; Troyanov, S, 2015) |
" To explore the role of Tbx1 in acute kidney injury (AKI) and the underlying mechanism, we detected the expression of Tbx1 and components of transforming growth factor-beta (TGF-β) signaling pathways including TGF-β, phosphorylated Smad2/3 (p-Smad2/3) and phosphorylated Smad1/5/8 (p-Smad1/5/8) in kidney tissues derived from a rat model for AKI induced by gentamicin (GM)." | 3.80 | Increased Tbx1 expression may play a role via TGFβ-Smad2/3 signaling pathway in acute kidney injury induced by gentamicin. ( Huang, Y; Jiang, H; Li, L; Li, Y; Li-Ling, J; Niu, Z; Qiu, G; Sun, K, 2014) |
" Body weight, daily fluid and feed intakes, and serum levels of creatinine, urea, and electrolytes were monitored on a weekly basis, and renal histology was evaluated at the end of the study." | 3.80 | Costus afer ker gawl leaves against gentamicin-induced nephrotoxicity in rats. ( Ezejiofor, AN; Orisakwe, OE; Orish, CN, 2014) |
"To investigate the incidence of acute kidney injury after cardiac surgery and its association with mortality in a patient population receiving ibuprofen and gentamicin perioperatively." | 3.80 | Acute kidney injury is independently associated with higher mortality after cardiac surgery. ( Jensen, ME; Kandler, K; Møller, CH; Nilsson, JC; Steinbrüchel, DA, 2014) |
"A sensitive urinary biomarker for acute kidney injury (AKI) was investigated in beagle dogs with nephrotoxicity induced by gentamicin." | 3.79 | Neutrophil gelatinase-associated lipocalin, a sensitive urinary biomarker of acute kidney injury in dogs receiving gentamicin. ( Kai, K; Kinoshita, J; Takasaki, W; Teranishi, M; Yamaguchi, T; Yoshimatsu, Y, 2013) |
"The clinical application of gentamicin has been limited by its nephrotoxicity, which is characterized by kidney injury, interstitial fibrosis and progressive renal impairment." | 3.79 | Plasmid pUDK-HGF encoding human hepatocyte growth factor gene attenuates gentamicin-induced kidney injury in rats. ( Chen, X; Chen, Z; Han, Y; Hu, C; Liu, X; Lu, Y; Wang, H; Wu, Z; Xiong, X; Zhang, Q, 2013) |
" We evaluated the pharmacokinetics and AKI potential of gentamicin in 14-week-old diet-induced obesity-prone (n = 40) and obesity-resistant (n = 40) rats of both sexes." | 3.79 | Effects of obesity and sex on antimicrobial pharmacokinetics and acute kidney injury: validation of a preclinical model. ( Chen, WZ; Cui, H; El-Fawal, HA; Garba, A; Mousa, SA; Pai, MP; Zaffo, B, 2013) |
"Current dosing recommendations for administration of gentamicin to septic patients with acute kidney injury (AKI) on continuous venovenous hemofiltration (CVVH) at a filtration rate of 45 ml/kg/h are missing." | 3.78 | Gentamicin pharmacokinetics during continuous venovenous hemofiltration in critically ill septic patients. ( Brozmanova, H; Duricova, J; Grundmann, M; Kacirova, I; Martinek, A; Petejova, N; Urbanek, K; Zahalkova, J, 2012) |
"This study evaluated the effects of bone marrow-derived mesenchymal stem cells (BMSCs) or their conditioned medium (CM) on the repair and prevention of Acute Kidney Injury (AKI) induced by gentamicin (G)." | 3.78 | Bone marrow-derived mesenchymal stem cells repaired but did not prevent gentamicin-induced acute kidney injury through paracrine effects in rats. ( Borges, AA; Borges, FT; Reis, LA; Schor, N; Simões, MJ; Sinigaglia-Coimbra, R, 2012) |
"Gentamicin nephrotoxicity is one of the most common causes of acute kidney injury (AKI)." | 3.78 | Hypoxia-inducible factor activation protects the kidney from gentamicin-induced acute injury. ( Ahn, JM; Ahn, SY; Chae, DW; Chin, HJ; Kim, S; Lee, YM; Na, KY; Oh, SW; You, SJ, 2012) |
"To report a case of acute renal failure after topical fortified gentamicin and vancomycin eyedrops in the treatment of endophthalmitis." | 3.77 | Acute renal failure after topical fortified gentamicin and vancomycin eyedrops. ( Tang, RK; Tse, RK, 2011) |
"The objective of the present prospective pharmacokinetic study was to describe the variability of plasma gentamicin concentrations in critically ill patients with acute kidney injury (AKI) necessitating extended daily diafiltration (EDD-f) using a population pharmacokinetic model and to subsequently perform Monte Carlo dosing simulations to determine which dose regimen achieves the pharmacodynamic targets the most consistently." | 3.76 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. ( Field, J; Kirkpatrick, CM; Lipman, J; Roberts, JA; Tallot, M; Visser, A; Whitbread, R, 2010) |
"Gentamicin is often used to treat infective endocarditis (IE)." | 3.75 | Severity of gentamicin's nephrotoxic effect on patients with infective endocarditis: a prospective observational cohort study of 373 patients. ( Bruun, NE; Buchholtz, K; Hassager, C; Larsen, CT, 2009) |
"The incidence of gentamicin-associated acute kidney injury (AKI) as defined by the RIFLE criteria is unknown." | 3.75 | Gentamicin-associated acute kidney injury. ( Fluck, RJ; Kolhe, NV; Selby, NM; Shaw, S; Woodier, N, 2009) |
" After 14 years of anorexia nervosa, the patient was treated for pneumonia with gentamicin at doses of 2 x 80 mg/24 h." | 3.73 | Regression of long standing anorexia nervosa following acute renal failure caused by gentamicin intoxication. ( Chodorowski, Z; Rutkowski, B; Rutkowski, P; Sein Anand, J, 2005) |
" Glomerular damage caused by puromycin aminonucleoside did not induce aminoaciduria until marked proteinuria occurred (day 9), and even then amino acid excretion was much less than that caused by gentamicin." | 3.68 | Aminoaciduria is an earlier index of renal tubular damage than conventional renal disease markers in the gentamicin-rat model of acute renal failure. ( Goldberg, DM; Macpherson, NA; Moscarello, MA, 1991) |
"Because rats with streptozotocin-induced diabetes mellitus (DM) have a high solute diuresis (glycosuria of 10 to 12 g/day), we have suggested that this may in part be responsible for their resistance to gentamicin-induced acute renal failure (ARF)." | 3.67 | Phlorizin-induced glycosuria does not prevent gentamicin nephrotoxicity in rats. ( Alpert, HC; Gouvea, WL; Kelley, J; Pardo, V; Vaamonde, CA, 1989) |
"The course of the excretion of dipeptidyl-peptidase IV (DP IV)-alanine aminopeptidase, beta-glucuronidase and total protein with the urine was investigated during the treatment of 11 patients with pyelonephritis with gentamicin, after application of a renal radiographic contrast medium in 7 patients with arterial hypertension and after regional perfusion of an extremity in 10 patients with malignant melanoma." | 3.67 | [Renal dipeptidylpeptidase IV excretion in drug-induced kidney changes]. ( Barth, A; Burchardt, U; Franke, M; Krauss, J, 1986) |
"After an initial episode of acute tubular necrosis, apparent resistance to gentamicin nephrotoxicity develops in rats during prolonged drug administration." | 3.67 | Chronic gentamicin nephrotoxicity. Continued tubular injury with preserved glomerular filtration function. ( Bennett, WM; Gilbert, DN; Houghton, DC; Lee, D, 1986) |
" The other woman had rheumatoid arthritis and developed acute tubular necrosis after treatment with gentamicin and cefoxitin." | 3.66 | Cefoxitin-associated renal failure. ( Bailey, RR; Reddy, J, 1981) |
"Acquired insensitivity to the nephrotoxic effects of gentamicin develops in Fischer 344 rats after 10 to 14 days' treatment after development of histologic acute tubular necrosis in a setting of extensive histologic regeneration." | 3.66 | Gentamicin nephrotoxicity. II. Definition of conditions necessary to induce acquired insensitivity. ( Baines-Hunter, J; Bennett, WM; Elliott, WC; Gilbert, DN; Houghton, DC, 1982) |
"This study describes an experimental model for the investigation of nephrotoxicity in which the aminoglycoside, gentamicin, is given after unilateral ureteral obstruction is produced." | 3.66 | Experimental evidence of increased ipsilateral gentamicin nephrotoxicity after unilateral ureteral obstruction. ( Karafin, L; Kendall, AR; Lillie, DB, 1981) |
"This paper reports our experience in monitoring gentamicin therapy during the treatment of 68 episodes of serious Gram-negative sepsis in 65 hospital patients." | 3.65 | Experience in monitoring gentamicin therapy during treatment of serious gram-negative sepsis. ( Garfield-Davies, D; Hughes, K; Noone, P; Parsons, TM; Pattison, JR; Slack, RC, 1974) |
"Acute kidney injury is a common complication in critically ill patients with sepsis and/or septic shock." | 2.66 | Acute Kidney Injury in Septic Patients Treated by Selected Nephrotoxic Antibiotic Agents-Pathophysiology and Biomarkers-A Review. ( Hrabovsky, V; Kacirova, I; Kanova, M; Klementa, V; Martinek, A; Petejova, N; Sigutova, R; Stejskal, D; Svagera, Z; Zadrazil, J, 2020) |
"To systematically review the frequency and type of adverse events associated with a single dose of intravenous or intramuscular gentamicin in adults, for any indication, in studies where a comparator was available." | 2.58 | Adverse effects of a single dose of gentamicin in adults: a systematic review. ( Harding, J; Hayward, RS; Land, L; Longcroft-Neal, K; Molloy, R; Moore, D; Ross, JDC, 2018) |
"Sepsis and septic shock are common cause of hospitalisation in intensive care unit." | 2.48 | [An effect of continuous and intermittent renal replacement therapy on antibiotic treatment in critically ill patients with sepsis - a practice-based perspective of vancomycin and gentamycin therapies]. ( Duricová, J; Grundmann, M; Kacířová, I; Martínek, A; Petejová, N; Plášek, J; Valkovský, I; Zahálková, J, 2012) |
"Gentamicin has been shown in both in vitro and in vivo studies to enhance the generation of reactive oxygen metabolites." | 2.40 | Oxidant mechanisms in toxic acute renal failure. ( Baliga, R; Shah, SV; Ueda, N; Walker, PD, 1997) |
"Gentamicin has been shown both in in vitro and in vivo studies to enhance the generation of reactive oxygen metabolites." | 2.40 | Oxidant mechanisms in toxic acute renal failure. ( Baliga, R; Shah, SV; Ueda, N; Walker, PD, 1999) |
" Despite the use of dosing nomograms, nephrotoxicity still occurs in some patients and the decline in renal function may only become apparent after completion of the antibiotic course." | 2.36 | Aminoglycoside nephrotoxicity: pathogenesis and prevention. ( Cronin, RE, 1979) |
"Gentamicin (GM) is an aminoglycoside antibiotic that induces nephrotoxicity." | 1.91 | L-cysteine protective effects against platelet disaggregation and echinocyte occurrence in gentamicin-induced kidney injury. ( Fočak, M; Mitrašinović-Brulić, M; Suljević, D, 2023) |
"Acute kidney injury is a common problem in dogs and is associated with significant morbidity and mortality." | 1.72 | Evaluation of symmetric dimethylarginine and Doppler ultrasonography in the diagnosis of gentamicin-induced acute kidney injury in dogs. ( Abdel-Raof, YM; Elgazzar, YMY; Ghanem, MM; Helal, MAY; Kandiel, MMM, 2022) |
" This study investigated the reporting risk of AKI associated with antibacterials using the individual case safety reports (ICSRs) submitted to the Food and Drug Administration Adverse Event Reporting System (FAERS) database." | 1.72 | Antibacterial-associated acute kidney injury among older adults: A post-marketing surveillance study using the FDA adverse events reporting system. ( Chinzowu, T; Chyou, TY; Nishtala, PS, 2022) |
"Gentamicin is a highly effective antibiotic." | 1.72 | Protective effect of empagliflozin on gentamicin-induced acute renal injury via regulation of SIRT1/NF-κB signaling pathway. ( Anter, A; Botros, SR; Heeba, GH; Khalifa, MMA; Matouk, AI, 2022) |
"Acute kidney injury is a serious health hazard disease due to its complex etiology and lack of effective treatments, resulting in high medical costs and high mortality." | 1.62 | Method used to establish a large animal model of drug-induced acute kidney injury. ( Cai, GY; Chen, XM; Wang, SY; Zhang, CY, 2021) |
"Gentamicin (GM) is an aminoglycoside antibiotic effectively used for severe/life-threatening infections." | 1.62 | Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity. ( Ali, FEM; El-Bahrawy, AH; Hassanein, EHM; Omar, ZMM; Sayed, AM, 2021) |
" Poor solubility and low bioavailability of Q as a bioflavonoid with potent antioxidant activity, limit its therapeutic application." | 1.62 | Quercetin-loaded F127 nanomicelles: Antioxidant activity and protection against renal injury induced by gentamicin in rats. ( Beyzaei, H; Bilal, M; Hasanein, P; Kyzas, GZ; Rahdar, A, 2021) |
"Daphnetin (Daph) is a natural coumarin derivative that is clinically used to treat rheumatoid arthritis and coagulopathy and exhibits antioxidant effects." | 1.62 | Daphnetin ameliorated GM-induced renal injury through the suppression of oxidative stress and apoptosis in mice. ( Ci, X; Fan, C; Fan, X; Gao, Y; Gu, W; Ma, N, 2021) |
"Gentamicin is an important broad-spectrum antibiotic; nevertheless, it exhibits serious nephrotoxic adverse effects." | 1.62 | HPLC-ESI/MS profiling, phytoconstituent isolation and evaluation of renal function, oxidative stress and inflammation in gentamicin-induced nephrotoxicity in rats of Ficus spragueana Mildbr. & Burret. ( Aboutabl, ME; Masoud, MA; Nassar, MI; Raslan, MA; Taher, RF, 2021) |
"Acute kidney injury affects nearly 30% of preterm neonates in the intensive care unit." | 1.56 | Nephron loss detected by MRI following neonatal acute kidney injury in rabbits. ( Baldelomar, EJ; Bennett, KM; Cathro, HP; Charlton, JR; Charlton, NP; Criswell, SJ; deRonde, KA; Hyatt, DM; Nam, S; Pearl, V, 2020) |
"Mice treated with gentamicin for 7 days developed AKI, and programmed cell death pathways were examined using pharmacologic inhibitors and in RIPK3-deficient mice." | 1.56 | Gentamicin-Induced Acute Kidney Injury in an Animal Model Involves Programmed Necrosis of the Collecting Duct. ( Capen, DE; Huang, H; Huang, M; Ji, H; Jin, WW; Lu, HAJ; Păunescu, TG; Xia, Y; Yuan, J, 2020) |
"Drug-induced acute kidney injury is a serious problem in drug development and clinical treatment." | 1.51 | Urinary biomarker evaluation for early detection of gentamycin-induced acute kidney injury. ( Chen, X; Cheng, G; Li, B; Miao, Y; Qu, Z; Sun, B; Sun, L; Yang, Y; Zhou, X, 2019) |
"Gentamicin (GM) is an antibiotic related to aminoglycoside group that is used in treating Gram-negative bacterial infections." | 1.51 | Combinational effect of curcumin and metformin against gentamicin-induced nephrotoxicity: Involvement of antioxidative, anti-inflammatory and antiapoptotic pathway. ( Cao, L; Han, J; Kumar Sah, S; Xie, Y; Zhi, D, 2019) |
" Thus, the model is generalizable, and can be used to deconvolute the underlying degree and time course of drug-induced PT injury and renal dysfunction from a small number of urinary biomarkers, and may provide a tool to determine optimal dosing regimens that minimize renal injury." | 1.48 | Multiscale Mathematical Model of Drug-Induced Proximal Tubule Injury: Linking Urinary Biomarkers to Epithelial Cell Injury and Renal Dysfunction. ( Gebremichael, Y; Hallow, KM; Helmlinger, G; Lu, J; Mettetal, J; Shankaran, H, 2018) |
" In conclusion, gentamicin is safe and has similar outcomes to alternative Gram-negative antimicrobial regimens for empirical coverage in severe CAP patients admitted to the ICU." | 1.48 | Is gentamicin safe and effective for severe community-acquired pneumonia? An 8-year retrospective cohort study. ( Brereton, CJ; Browning, S; Davis, JS; Dunn, E; Ferguson, JK; Lennon, D, 2018) |
"External validation of population pharmacokinetic (PK) models is warranted before they can be clinically applied to aid in antibiotic dose selection." | 1.48 | Predictive performance of a gentamicin population pharmacokinetic model in two western populations of critically ill patients. ( Bukkems, LH; Hodiamont, CJ; Juffermans, NP; Lefrant, JY; Roberts, JA; Roger, C; van Hest, RM, 2018) |
"Acute renal failure is one of the most frequent effects observed after taking medicine." | 1.48 | In vitro evaluation of biomarkers of nephrotoxicity through gene expression using gentamicin. ( Campos, MAA; de Almeida, LA; Grossi, MF; Tagliati, CA, 2018) |
" The aim of this study was to compare renal function, renal recovery and mortality in a large cohort of patients with bacteraemia, who were empirically treated with regimens with and without a short course (≤ 3 days) of once daily dosing of gentamicin." | 1.48 | The effect of short-course gentamicin therapy on kidney function in patients with bacteraemia-a retrospective cohort study. ( Arpi, M; Boel, J; Carlsen, S; Gjørup, I; Jarløv, JO; Søborg, C, 2018) |
"Treatment of gentamicin-induced nephrotoxicity with either HBOT or 100% oxygen for 5 days had no beneficial renal effect." | 1.46 | Hyperbaric oxygen treatment and nephrotoxicity induced by gentamicin in rats. ( Abu-Kishk, I; Berkovitch, M; Goldman, M; Kozer, E; Shain, Y, 2017) |
" We found a change in cell viability after 24h incubation with all tested toxic compounds." | 1.46 | Neutrophil gelatinase-associated lipocalin production negatively correlates with HK-2 cell impairment: Evaluation of NGAL as a marker of toxicity in HK-2 cells. ( Čapek, J; Flídr, P; Hauschke, M; Libra, A; Roušar, T; Roušarová, E, 2017) |
"However, the presence of a patent ductus arteriosus, concomitant non-steroidal anti-inflammatory drug use, ≥1 positive blood cultures, low birth weight and higher severity of illness and risk of mortality scores were associated with an increased risk of nephrotoxicity." | 1.43 | A propensity-matched cohort study of vancomycin-associated nephrotoxicity in neonates. ( Balch, AH; Constance, JE; Korgenski, EK; Linakis, MW; Roberts, JK; Sherwin, CM; Spigarelli, MG; Stockmann, C; Ward, RM, 2016) |
"Mean gentamicin dose was 4." | 1.43 | No increased risk of acute kidney injury after a single dose of gentamicin in patients with sepsis. ( Cobussen, M; de Kort, JM; Dennert, RM; Lowe, SH; Stassen, PM, 2016) |
"Antibiotic administration during the treatment of open fractures has been shown to reduce infection rates and is considered a critical step in the management of these injuries." | 1.43 | Antibiotic related acute kidney injury in patients treated for open fractures. ( Banks, K; Hahn, J; Inaba, K; Marecek, GS; Pannell, WC, 2016) |
" Cardiotrophin-1 (CT-1), a member of the IL-6 family of cytokines, has been reported to protect the kidney against toxic and ischemic acute kidney injury (AKI)." | 1.43 | Cardiotrophin-1 therapy prevents gentamicin-induced nephrotoxicity in rats. ( Blanco-Gozalo, V; López-Hernandez, FJ; López-Novoa, JM; Perez de Obanos, MP; Quirós, Y; Ruiz, J; Sanchez-Gallego, JI, 2016) |
"Gentamicin-treated rats demonstrated impaired renal function by attenuation of creatinine clearance and increased oxidative stress." | 1.43 | Atorvastatin improves renal organic anion transporter 3 and renal function in gentamicin-induced nephrotoxicity in rats. ( Arjinajarn, P; Chatsudthipong, V; Chattipakorn, N; Jaikumkao, K; Lungkaphin, A; Pongchaidecha, A; Promsan, S, 2016) |
"Gentamicin treatment also stimulated Nrf2, HO-1, and NQO1, as well as the pro-apoptotic proteins Bax and caspase-3, concomitant with the attenuation of Bcl-XL expression in the renal cortical tissues." | 1.43 | Pinocembrin attenuates gentamicin-induced nephrotoxicity in rats. ( Arjinajarn, P; Chatsudthipong, V; Chattipakorn, N; Jaikumkao, K; Lungkaphin, A; Pompimon, W; Pongchaidecha, A; Promsan, S, 2016) |
"Gentamicin was not associated with AKI (odds ratio [OR] 0." | 1.43 | Prophylactic Gentamicin Is Not Associated with Acute Kidney Injury in Patients with Open Fractures. ( Duane, TM; Gandhi, RR; Moore, B; Putty, B; Tessier, JM, 2016) |
"Gentamicin is an effective aminoglycoside antibiotic employed against severe Gram-negative bacterial infections, but induction of nephrotoxicity limits its frequent clinical use." | 1.42 | Nephroprotective effect of catechin on gentamicin-induced experimental nephrotoxicity. ( Balakumar, P; Kalra, S; Khanna, D; Sardana, A, 2015) |
" Due to dosage adjustment and appropriate monitoring, most therapeutic courses with cisplatin produce no or minimal kidney damage." | 1.42 | Sub-nephrotoxic cisplatin sensitizes rats to acute renal failure and increases urinary excretion of fumarylacetoacetase. ( Blanco-Gozalo, V; García-Sánchez, O; González-Buitrago, JM; López-Hernández, FJ; López-Novoa, JM; Morales, AI; Pescador, M; Sánchez-Juanes, F; Sevilla, MA; Vicente-Vicente, L, 2015) |
"Gentamicin is a widely used antibiotic against serious and life-threatening infections; however, its usefulness is limited by the development of nephrotoxicity." | 1.42 | Flavocoxid attenuates gentamicin-induced nephrotoxicity in rats. ( El-Kashef, DH; El-Kenawi, AE; Salem, HA; Suddek, GM, 2015) |
"Gentamicin was associated with a significant increase in AKI (1 vs." | 1.40 | Antibiotic-associated complications following lower limb arthroplasty: a comparison of two prophylactic regimes. ( Bayley, E; Craxford, S; Needoff, M, 2014) |
"Gentamicin is a member of aminoglycosides, which has represented highly effective antimicrobial agents especially in Gram-negative infections despite their toxic effects in the kidney." | 1.40 | KIM-1 and NGAL as biomarkers of nephrotoxicity induced by gentamicin in rats. ( Chen, ML; Chen, ZL; Cheng, AC; Fang, J; Geng, Y; Gong, L; Li, MY; Luo, QH; Peng, X; Sun, FJ; Tang, L; Zeng, W, 2014) |
"Gentamicin was used as a damage factor in the culture of renal tubular epithelial cells (RTECs) in vitro." | 1.39 | Study on therapeutic action of bone marrow derived mesenchymal stem cell combined with vitamin E against acute kidney injury in rats. ( Dong, C; Feng, Y; Liu, D; Liu, P; Lv, P; Wu, H; Wu, X; Zhou, Y, 2013) |
" Thus, this study was designed to investigate whether a Korean red ginseng extract (KRG) prevents renal impairment and pharmacokinetic changes by metformin in rats with renal failure induced by gentamicin." | 1.39 | Effects of Korean red ginseng extract on acute renal failure induced by gentamicin and pharmacokinetic changes by metformin in rats. ( Chin, YW; Choi, YH; Lee, YK, 2013) |
"Nephrotoxicity is a serious side effect of gentamicin and is believed to be related to reactive oxygen species in the kidney." | 1.39 | Ethanolic extract of garlic for attenuation of gentamicin-induced nephrotoxicity in Wistar rats. ( Nasri, H; Nematbakhsh, M; Rafieian-Kopaei, M, 2013) |
" To this end, rats were treated with a subtoxic dosage of the experimental nephrotoxin uranyl nitrate (UN) in the drinking water for 21 weeks, or plain water (as control), and then with low-dose gentamicin for 7 days." | 1.39 | Increased urinary excretion of albumin, hemopexin, transferrin and VDBP correlates with chronic sensitization to gentamicin nephrotoxicity in rats. ( Ferreira, L; González-Buitrago, JM; López-Hernández, FJ; López-Novoa, JM; Morales, AI; Vicente-Vicente, L, 2013) |
"Acute renal failure was induced by gentamicin, an aminoglycoside antibiotic whose utilization over prolonged periods causes nephrotoxicity." | 1.39 | Acute renal failure potentiates methylmalonate-induced oxidative stress in brain and kidney of rats. ( Alves, L; Dal-Pizzol, F; Felisberto, F; Ferreira, GC; Freitas, BW; Petronilho, F; Pettenuzzo, LF; Rodrigues, LB; Schuck, PF; Streck, EL, 2013) |
" xanthocarpum fruit extract acts in the kidney as a potent scavenger of free radicals to prevent the toxic effects of GM both in the biochemical and histopathological parameters and thus validates its ethnomedicinal use." | 1.38 | Nephroprotective activity of Solanum xanthocarpum fruit extract against gentamicin-induced nephrotoxicity and renal dysfunction in experimental rodents. ( Eswaran, B; Gupta, RK; Hussain, T; Rao, CV; Sweety, K; Vijayakumar, M, 2012) |
"Our results suggested that HDN acts as a potent scavenger of free radicals in the kidney to prevent the toxic effects of GEN both at the biochemical and histopathological levels." | 1.38 | Renal protective effect of hesperidin on gentamicin-induced acute nephrotoxicity in male Wistar albino rats. ( Anandan, R; Subramanian, P, 2012) |
"Gentamicin (GM) is an effective aminoglycoside antibiotic against life-threatening Gram-negative bacteria." | 1.37 | The protective effect of eugenol against gentamicin-induced nephrotoxicity and oxidative damage in rat kidney. ( Said, MM, 2011) |
" The nephrotoxin gentamicin was given to rats once on each of three days and the animals were killed during dosing or over the following 42 days." | 1.37 | Comparative profile of commercially available urinary biomarkers in preclinical drug-induced kidney injury and recovery in rats. ( Espandiari, P; Rosenzweig, BA; Rouse, RL; Sadrieh, NK; Stewart, SR; Zhang, J, 2011) |
"Gentamicin treatment caused nephrotoxicity as evidenced by marked elevation in serum creatinine, blood urea nitrogen, renal malondialdehyde, urine sodium, and fractional excretion of sodium." | 1.37 | Evaluation of efficacy of vitamin E and N-acetyl cysteine in gentamicin-induced nephrotoxicity in rats. ( Deshpande, S; Patel Manali, B; Shah, G, 2011) |
"Gentamicin was injected at a dose of 40 mg/kg body weight (the first treated group) and 80 mg/kg body weight (the second treated group) for 14 days." | 1.36 | Distribution and amount of cathepsin B in gentamicin-induced acute kidney injury in rats. ( Juntes, P; Pogacnik, M; Svara, T, 2010) |
"In this study, approximately 40 endogenous metabolites were identified and quantified by (1)H NMR in urine samples from male rats dosed with two proximal tubule toxicants, cisplatin and gentamicin." | 1.35 | Integrated pathway analysis of rat urine metabolic profiles and kidney transcriptomic profiles to elucidate the systems toxicology of model nephrotoxicants. ( Aslamkhan, AG; Brennan, RJ; Perlina, A; Troth, SP; Vu, H; Xu, EY; Xu, Q, 2008) |
"Gentamicin (GM) is a widely used antibiotic against serious and life-threatening infections, but its usefulness is limited by the development of nephrotoxicity." | 1.35 | Protective effects of pentoxifylline treatment on gentamicin-induced nephrotoxicity in rats. ( Mihailovic, D; Radenkovic, M; Randjelovic, P; Rankovic, G; Stoiljkovic, M; Stojiljkovic, N; Veljkovic, S, 2009) |
"In this study we postulated that during acute renal failure induced by gentamicin the transient or dynamic response of blood vessels could be affected, and that antioxidants can prevent the changes in dynamic responses of blood vessels." | 1.35 | Dynamic response of blood vessel in acute renal failure. ( Obradovic, Z; Pantovic, S; Rankovic, G; Rosic, G; Rosic, M; Stojiljkovic, N, 2009) |
"Gentamicin is an aminoglycoside antibiotic that induces severe nephrotoxicity and acute renal failure." | 1.35 | Role of tissue kallikrein in prevention and recovery of gentamicin-induced renal injury. ( Bledsoe, G; Chao, J; Chao, L; Grass, D; Hagiwara, M; Mizell, B; Shen, B; Teuton, M; Yao, YY, 2008) |
"Data are limited on aminoglycoside pharmacokinetic differences between acute renal failure (ARF) and chronic kidney disease (CKD) or infection survival when maintaining peak and pre-hemodialysis serum concentrations between 7 and 10 and 3." | 1.33 | Aminoglycosides in intermittent hemodialysis: pharmacokinetics with individual dosing. ( Dager, WE; King, JH, 2006) |
"Focusing on the disposition of cyclosporin A (CsA) in the liver and intestine, effects of gentamicin-induced acute renal failure (ARF) on the decreased oral bioavailability of CsA were evaluated in rats." | 1.32 | Evaluation of factors to decrease bioavailability of cyclosporin A in rats with gentamicin-induced acute renal failure. ( Fukumoto, K; Fukushima, K; Inoue, Y; Nishimura, A; Shibata, N; Spiteller, G; Takada, K; Yoshikawa, Y, 2004) |
" From these findings, we concluded that a reduction of CsA bioavailability during ARF is caused by depression in bile excretion and renal function-dependent depression of uptake from intestinal tract via maybe P-gLycoprotein in enterocytes." | 1.31 | Factors that affect absorption behavior of cyclosporin a in gentamicin-induced acute renal failure in rats. ( Hoshino, N; Minouchi, T; Morimoto, J; Shibata, N; Yamaji, A, 2000) |
"Gentamicin was observed to cause a severe nephrotoxicity which was evidenced by an elevation of BUN and creatinine levels." | 1.31 | Melatonin protects against gentamicin-induced nephrotoxicity in rats. ( Altunbas, HZ; Arbak, S; Ayanoglu-Dulger, G; Ersoy, Y; Paskaloglu, K; Sehirli, AO; Sener, G, 2002) |
"However at the 14th day, an acute renal failure occurred, following macroscopic haematuria and milkiness urine." | 1.30 | [Obstructive renal insufficiency caused by amoxicillin crystalluria]. ( Benhassine, L; Boursas, M; Kempf, J; Petit, B; Vuillemin, F, 1997) |
"Gentamicin was given i." | 1.30 | Kidney ectopeptidases in gentamicin and mercuric chloride-induced acute renal failure. ( Ilić, S; Mitić-Zlatković, M; Savić, V; Stefanović, V; Vlahović, P, 1998) |
"Gentamicin-induced acute renal failure is characterized by a decrease in renal plasma flow and creatinine clearance." | 1.30 | Increased renal glomerular endothelin-1 release in gentamicin-induced nephrotoxicity. ( Arévalo, M; López-Novoa, JM; Morales, AI; Pérez-Barriocanal, F; Rivas-Cabañero, L; Valdivielso, JM, 1999) |
"Phospholipidosis thesauruses, noted in acute renal failure induced by GM, is considered to be caused by reduced liberation of lysosomal intramembranous phospholipid into the cytoplasm and accelerated peroxidation of intramembranous lipid." | 1.29 | [Lipid peroxidation and tubular disorder in experimental acute renal failure-enzymochemical study in the rat kidney]. ( Fukuoka, T; Ishizuka, S; Nagasawa, T; Soejima, A; Suzuki, M, 1994) |
"Gentamicin (GM) often causes polyuric acute renal failure (ARF) in humans and animals." | 1.29 | Roles of hemodynamic and tubular factors in gentamicin-mediated nephropathy. ( Hishida, A; Honda, N; Kato, A; Nakajima, T; Yamada, M, 1994) |
"30 adult, female, mixed-breed dogs, allotted to 3 groups of 10 dogs each as: toxic dosage of gentamicin, therapeutic dosage of gentamicin, and saline solution sham equivalent in volume to that of the toxic dosage of gentamicin." | 1.29 | Estimation of arcuate artery resistive index as a diagnostic tool for aminoglycoside-induced acute renal failure in dogs. ( Finlay, DE; King, VL; Letourneau, JG; O'Brien, TD; Polzin, DJ; Ritenour, ER; Rivers, BJ; Walter, PA, 1996) |
"Gentamicin sulfate was subcutaneously injected at a dose of 200 mg/kg for 5 consecutive days." | 1.29 | Protective effect of human ulinastatin against gentamicin-induced acute renal failure in rats. ( Kudo, M; Mizota, M; Nakakuki, M; Shinkawa, T; Watanabe, M; Yamasaki, F, 1996) |
" Possible mechanisms of CS on drug-induced nephrotoxicity include: (1) Accelerating the regeneration of tubular cells; (2) Protecting the sodium pump activity of tubular cells; (3) Attenuating the tubular cell lysosome hyperfunction stimulated by phagocytosis of AG as well as decreasing the tubular cell lipoperoxidation in response to toxic injury; (4) Reducing the tissue Ca++ content." | 1.29 | [Experimental study on effect of Cordyceps sinensis in ameliorating aminoglycoside induced nephrotoxicity]. ( Li, LS; Liu, ZH; Zheng, F, 1996) |
" Intrarenal infusion ET in dosage of 0." | 1.28 | [Endothelin and acute renal failure: study on their relation and possible mechanisms]. ( Lin, S, 1992) |
"Acute renal failure following hemorrhagic shock was studied in awake rats." | 1.28 | Acute renal failure following hemorrhagic shock: protective and aggravating factors. ( Rocha, AS; Seguro, AC; Yu, L, 1992) |
"To investigate the feasibility of predicting gentamicin dosing requirements during continuous arteriovenous hemodiafiltration (CAVHD)." | 1.28 | Gentamicin clearance during continuous arteriovenous hemodiafiltration. ( Cutler, DJ; Ernest, D, 1992) |
" The tubular toxic symptoms which ensure (inactivation of membranaceous enzyme, reduction of microsomal protein synthesis and ATP level, decreased of solute reabsorptive flux) lead in turn to proximal tubular necrosis and acute renal failure." | 1.28 | [Effects of the calcium-channel blocker diltiazem on gentamicin-induced nephrotoxicity in rats]. ( Gibey, R; Henry, JC, 1991) |
" Significant differences between treated and control groups, compatible with enhancement of gentamicin elimination, were observed in the calculated pharmacokinetic parameters (Kel, t 1/2, CL and AUC)." | 1.28 | The effect of oral activated charcoal on the systemic clearance of gentamicin in rabbits with acute renal failure. ( Abdelaziz, AA; el-Sayed, YM; Hasan, MM, 1990) |
" Additional nutritional factors may play a crucial role in achieving the amelioration of this model of toxic nephropathy." | 1.28 | The effect of oral calcium load or verapamil on gentamicin-induced nephrotoxicity. ( Aladjem, M; Bogin, E; Tamir, A, 1989) |
"As concomitant factor inducing acute renal failure together with antibiotics are: elderly, hepatopathy, surgical interventions, administration of other nephrotoxic drugs." | 1.28 | [Acute renal insufficiency after the administration of tetracycline and gentamycin]. ( Deák, J; Demes, M; Gocár, E; Kovác, A; Krcméry, V; Menkyna, R; Pribylincová, V; Stankovic, I; Vevercáková, M, 1989) |
" Although adequate maintenance dosing requires individualization based on pharmacokinetic analyses, large aminoglycoside doses can be used safely in patients with blunt trauma if appropriate monitoring is employed." | 1.28 | Aminoglycoside pharmacokinetics: dosage requirements and nephrotoxicity in trauma patients. ( Fink, MP; Murphy, SG; Stein, KL; Townsend, PL, 1989) |
"Lysine is a major constituent of hyperalimentation solutions and is known to inhibit tubular reabsorption of protein." | 1.27 | Nephrotoxicity of lysine and of a single dose of aminoglycoside in rats given lysine. ( Malis, CD; Racusen, LC; Solez, K; Whelton, A, 1984) |
"Gentamicin was given at a dosage of 100 mg/kg/day subcutaneously for either 4 or 5 days to Sprague-Dawley rats and resulted in a reversible, polyuric form of acute renal failure." | 1.27 | The renal concentrating defect after gentamicin administration in the rat. ( Anderson, RJ; Dillingham, MA; Gordon, JA; Grossfeld, PD; Guggenheim, SJ, 1983) |
"Gentamicin sulfate was administered by intraperitoneal injection to male Sprague-Dawley rats in a dose of 100 to 120 mg/kg/day for 4 to 5 days to induce severe nephrotoxicity." | 1.27 | Role of tubular obstruction in acute renal failure due to gentamicin. ( Aynedjian, HS; Bank, N; Neugarten, J, 1983) |
"Gentamicin has been shown to induce renal tubular damage in man and laboratory animals and to result in elevated urinary excretion of some enzymes associated with specific cell regions in the kidney." | 1.27 | Protection by selenium against gentamicin-induced acute renal damage in the rat. ( Madusolumuo, MA; Ngaha, EO; Ogunleye, IO, 1984) |
"A patient developed acute renal failure while receiving oral procainamide (PA)." | 1.27 | Procainamide toxicity in a patient with acute renal failure. ( Brady, ME; Rosansky, SJ, 1986) |
"Indomethacin treatment (2 mg kg-1 day-1, ip, for 13 days) of rats which received gentamicin or tobramycin (40 mg kg-1 day-1, ip, for 10 days) caused a further fall in glomerular filtration rate (GFR) and renal blood flow and an impressive increase in renal resistance." | 1.27 | Role of the prostaglandin and kallikrein-kinin systems in aminoglycoside-induced acute renal failure. ( Ajzen, H; Boim, MA; Higa, EM; Ramos, OL; Schor, N, 1985) |
"Human acute renal failure is accompanied by an increase in parathyroid hormone (PTH), a hormone that stimulates calcium uptake by tissues, and by a decrease in thyroid hormone, a hormone that increases renal cortex Na-K-ATPase activity." | 1.27 | Protective effect of thyroxine but not parathyroidectomy on gentamicin nephrotoxicity. ( Cronin, RE; Newman, JA, 1985) |
"Rats treated with gentamicin (G) alone (100 mg/kg, s." | 1.27 | Evidence suggesting a role for hydroxyl radical in gentamicin-induced acute renal failure in rats. ( Shah, SV; Walker, PD, 1988) |
"Aminoglycoside-induced acute renal failure was more prevalent in the gentamicin group (42." | 1.27 | [An early and specific indicator of aminoglycoside nephrotoxicity: isoenzyme B of urinary N-acetyl-beta-D-glucosaminidase (NAG)]. ( Dupond, JL; Gibey, R; Henry, JC; Iehl-Robert, M; Peltier, H, 1986) |
"Only two patients developed transient acute renal failure during the first 10 days of treatment." | 1.27 | [Isoenzymes of N-acetyl-beta-D-glucosaminidase (NAG): new method of evaluating the nephrotoxicity of aminosides. Our experience with dibekacin in geriatrics]. ( Becker, M; Dupond, JL; Flausse-Parrot, F; Gibey, R; Guerber, F; Iehl-Robert, M; Mallet, H, 1986) |
"Gentamicin-associated acute renal failure was diagnosed in 10 dogs." | 1.27 | Gentamicin-associated acute renal failure in the dog. ( Barsanti, JA; Brown, SA; Crowell, WA, 1985) |
"Captopril pretreatment did not influence the results." | 1.26 | The renin-angiotensin system in aminoglycoside-induced acute renal failure. ( Aronoff, GR; Connors, BA; Evan, AP; Kleit, SA; Luft, FC; Weinberger, MH, 1982) |
"150 gentamicin-PMMA-beads were implanted (+ 160 mg gentamicin i." | 1.26 | Treatment of a patient with impaired renal function with gentamicin-PMMA-beads. ( Vree, TB; Walenkamp, GH, 1981) |
"Acute renal failure was induced in rats by subcutaneous injection of 200 mg/kg body weight gentamicin on 3 consecutive days." | 1.26 | Gentamicin-induced acute renal failure in the rat. Effect of dehydration, DOCA-saline and furosemide. ( Brunner, FP; de Rougemont, D; Konrad, L; Oeschger, A; Thiel, G; Torhorst, J; Wenk, M; Wunderlich, P, 1981) |
"However, an eighth patient with acute renal failure caused by bacteraemic shock rapidly recovered renal function while being treated with cefuroxime and gentamicin for 15 days after large doses of frusemide intravenously." | 1.26 | The safety of cefuroxime and gentamicin in patients with reduced renal function. ( Bax, RP; Cockram, CS; Richards, P, 1980) |
"The etiology of acute renal failure has changed in recent years due to the recognition of drug nephrotoxicity as a more common cause." | 1.26 | Pathogenesis of renal failure due to aminoglycosides and contrast media used in roentgenography. ( Bennett, WM; Luft, F; Porter, GA, 1980) |
"Peak serum levels of gentamicin were varied in rats by administering a standard nephrotoxic dosage of 40 mg/kg per day in one (QD), two, or three (TID) daily doses." | 1.26 | The influence of dosage regimen on experimental gentamicin nephrotoxicity: dissociation of peak serum levels from renal failure. ( Bennett, WM; Gilbert, DN; Parker, RA; Plamp, CE; Porter, GA, 1979) |
"The Authors describe one case of acute renal insufficiency in a patient treated with high doses of gentamicin over a period of three weeks." | 1.26 | [Cytosegregosomes in the kidney tubule cells in a case of acute renal insufficiency (ARI) caused by gentamycin]. ( Borghi, M; Olivetti, G; Pecchini, F, 1979) |
"A 31 year old woman presented with acute renal failure and pyelonephritis." | 1.26 | Malacoplakia of the kidney: apparent improvement following medical management. ( Bhathena, D; Galla, JH, 1978) |
"A case of acute renal insufficiency after therapy with gentamycin and beta-Aescin is reported." | 1.26 | [Acute posttraumatic renal failure following therapy with antibiotics and beta-aescin (author's transl)]. ( Junger, H; Voigt, E, 1978) |
"Rats recovering from HgCl2-induced acute renal failure were resistant to a depression in glomerular filtration when given gentamicin." | 1.26 | The effect of concomitant mercuric chloride and gentamicin on kidney function and structure in the rat. ( Kleit, SA; Luft, FC; Yum, MN, 1977) |
" The nephrotoxicity of gentamicin is poor but well established, and may be prevented by checking the initial renal function, adjusting the dosage subsequently, and monitoring the renal function and gentamicin serum levels during therapy." | 1.26 | [Nephrotoxicity of gentamicin. Conditions for the use of this antibiotic in the elderly and in the patient with renal insufficiency]. ( Ganeval, D; Jungers, P; Kleinknecht, D, 1977) |
"Acute renal failure (ARF) occurred concomitantly with the administration of gentamicin in combination with clindamycin in three patients in whom no other known predisposing cause of ARF could be demonstrated." | 1.26 | Renal failure following gentamicin in combination with clindamycin. ( Butkus, DE; de Torrente, A; Terman, DS, 1976) |
"Gentamicin sulfate was given to rabbits for four weeks in two dosage regimens, either 4 or 8 mg/kg subcutaneously twice a day." | 1.26 | Renal glycosuria due to gentamicin in rabbits. ( Ginsburg, DS; Levin, M; Quintanilla, AP, 1976) |
" The morphologically immature regenerating cells are apparently metabolically immature as well and appear not to be susceptible to toxic effects of the drug." | 1.26 | A light and electron microscopic analysis of gentamicin nephrotoxicity in rats. ( Bennett, W; Campbell-Boswell, M; Hartnett, M; Houghton, DC; Porter, G, 1976) |
" The dosage of these drugs was much higher than the usual upper limbs, beta-aescin in doses as high as 10 to 20 fold above recommended maximum." | 1.25 | [Acute renal failure after intracranial injury in three children: analysis of possible causes (author's transl)]. ( Brandis, M; Brodehl, J; Krohn, HP; Offner, G; Onken, D, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 181 (37.79) | 18.7374 |
1990's | 51 (10.65) | 18.2507 |
2000's | 43 (8.98) | 29.6817 |
2010's | 158 (32.99) | 24.3611 |
2020's | 46 (9.60) | 2.80 |
Authors | Studies |
---|---|
Elgazzar, YMY | 1 |
Ghanem, MM | 1 |
Abdel-Raof, YM | 1 |
Kandiel, MMM | 1 |
Helal, MAY | 1 |
Fatimah, SN | 1 |
Usman, SM | 1 |
Fatima, SN | 1 |
Akhtar, S | 1 |
Shahid, SM | 1 |
Sajjad, A | 1 |
Bibi, A | 1 |
Pacheco, LF | 1 |
de Castro, CH | 1 |
Dutra, JBR | 1 |
de Souza Lino Junior, R | 2 |
Ferreira, PM | 1 |
Dos Santos, RAS | 1 |
Ulhoa, CJ | 1 |
Babaeenezhad, E | 1 |
Dezfoulian, O | 1 |
Hadipour Moradi, F | 1 |
Rahimi Monfared, S | 1 |
Fattahi, MD | 1 |
Nasri, M | 1 |
Amini, A | 1 |
Ahmadvand, H | 1 |
Petejova, N | 4 |
Martinek, A | 4 |
Zadrazil, J | 2 |
Klementa, V | 2 |
Pribylova, L | 1 |
Bris, R | 1 |
Kanova, M | 2 |
Sigutova, R | 2 |
Kacirova, I | 4 |
Svagera, Z | 2 |
Bace, E | 1 |
Stejskal, D | 2 |
Sharma, I | 1 |
Liao, Y | 1 |
Zheng, X | 1 |
Kanwar, YS | 1 |
Chinzowu, T | 1 |
Chyou, TY | 1 |
Nishtala, PS | 1 |
Botros, SR | 1 |
Matouk, AI | 1 |
Anter, A | 1 |
Khalifa, MMA | 1 |
Heeba, GH | 1 |
Suljević, D | 1 |
Mitrašinović-Brulić, M | 1 |
Fočak, M | 1 |
Alharbi, KS | 1 |
Ali, T | 1 |
Singh, Y | 1 |
Ali Al-Ghamdi, AS | 1 |
Kazmi, I | 1 |
Al-Abbasi, FA | 1 |
Alzarea, SI | 1 |
Afzal, O | 1 |
Alfawaz Altamimi, AS | 1 |
Singh, SK | 1 |
Chellappan, DK | 1 |
Dua, K | 1 |
Gupta, G | 1 |
Ali, A | 2 |
Khan, H | 1 |
Kahrizi, D | 1 |
Pervez, S | 1 |
Alotaibi, G | 1 |
Rastrelli, L | 1 |
Judd, H | 1 |
Benito, J | 1 |
Pannu, TS | 1 |
Villa, JM | 1 |
Higuera, CA | 1 |
Corces, A | 1 |
Hu, BF | 1 |
Gong, Q | 1 |
Chen, SQ | 1 |
Yue, L | 1 |
Ma, WX | 1 |
Wang, F | 1 |
Feng, XW | 1 |
Wang, JN | 1 |
Li, C | 1 |
Liu, MM | 1 |
Wang, XF | 1 |
Meng, XM | 1 |
Li, J | 1 |
Wen, JG | 1 |
Xu, XJ | 1 |
Zhang, ML | 1 |
Hou, YM | 1 |
Zhang, K | 1 |
Yao, DH | 1 |
Li, GY | 1 |
Kou, WB | 1 |
Wang, HY | 1 |
Wang, JH | 1 |
Abdelzaher, WY | 3 |
El-Tahawy, NFG | 3 |
AboBakr Ali, AHS | 3 |
Mohamed, HA | 3 |
Welson, NN | 3 |
Aly Labib, DA | 3 |
Elkhoely, A | 2 |
Good, PI | 1 |
Li, L | 2 |
Hurst, HA | 1 |
Serrano Herrera, I | 1 |
Xu, K | 1 |
Rao, M | 1 |
Bateman, DA | 1 |
Al-Awqati, Q | 1 |
D'Agati, VD | 1 |
Costantini, F | 1 |
Lin, F | 1 |
Fisk, A | 1 |
Londoño, L | 1 |
Carrera-Justiz, S | 1 |
Buckley, G | 1 |
Rasheed, HA | 1 |
Al-Kuraishy, HM | 1 |
Al-Gareeb, AI | 1 |
Abd El-Lateef, SM | 1 |
El-Sayed, EM | 1 |
Mansour, AM | 1 |
Salama, SA | 2 |
Charlton, JR | 2 |
Baldelomar, EJ | 2 |
deRonde, KA | 1 |
Cathro, HP | 1 |
Charlton, NP | 1 |
Criswell, SJ | 1 |
Hyatt, DM | 1 |
Nam, S | 1 |
Pearl, V | 1 |
Bennett, KM | 2 |
Duffy, CR | 1 |
Huang, Y | 2 |
Andrikopoulou, M | 1 |
Stern-Ascher, CN | 1 |
Wright, JD | 1 |
Goffman, D | 1 |
D'Alton, ME | 1 |
Friedman, AM | 1 |
Han, C | 1 |
Sun, T | 1 |
Liu, Y | 2 |
Fan, G | 1 |
Zhang, W | 1 |
Liu, C | 1 |
Sancho-Martínez, SM | 3 |
Blanco-Gozalo, V | 3 |
Quiros, Y | 4 |
Prieto-García, L | 1 |
Montero-Gómez, MJ | 1 |
Docherty, NG | 1 |
Martínez-Salgado, C | 2 |
Morales, AI | 5 |
López-Novoa, JM | 8 |
López-Hernández, FJ | 7 |
Igwebuike, C | 1 |
Yaglom, J | 1 |
Huiting, L | 1 |
Feng, H | 1 |
Campbell, JD | 1 |
Wang, Z | 2 |
Havasi, A | 1 |
Pimentel, D | 1 |
Sherman, MY | 1 |
Borkan, SC | 1 |
Parvin, N | 1 |
Derakhshan, JJ | 1 |
Vlasakova, K | 1 |
Troth, SP | 2 |
Sistare, FD | 1 |
Glaab, WE | 1 |
Huang, H | 1 |
Jin, WW | 1 |
Huang, M | 1 |
Ji, H | 1 |
Capen, DE | 1 |
Xia, Y | 1 |
Yuan, J | 1 |
Păunescu, TG | 1 |
Lu, HAJ | 1 |
Gommans, EPAT | 1 |
Aarnoudse, ALHJ | 1 |
van Wensen, RJA | 1 |
van Erp-van Boekel, AAW | 1 |
Grouls, RJE | 1 |
van der Linden, CMJ | 1 |
Liljedahl Prytz, K | 1 |
Prag, M | 1 |
Fredlund, H | 1 |
Magnuson, A | 1 |
Sundqvist, M | 1 |
Källman, J | 1 |
Sharawy, MH | 1 |
Serrya, MS | 1 |
Wang, L | 2 |
Wang, J | 2 |
Luo, J | 1 |
Ruan, H | 2 |
Zhang, J | 5 |
Hrabovsky, V | 1 |
Silva de Almeida, TC | 1 |
Lanza, K | 1 |
da Silva Filha, R | 1 |
C Campos, LMC | 1 |
Fonseca, EG | 1 |
Chagas, MW | 1 |
Rocha, NP | 1 |
de Sá, MA | 1 |
Vieira, MAR | 1 |
Caliari, MV | 1 |
Kangussu, LM | 1 |
Ferreira, AJ | 1 |
Simões E Silva, AC | 1 |
Jeon, BS | 1 |
Lee, SH | 1 |
Hwang, SR | 1 |
Yi, H | 1 |
Bang, JH | 1 |
Tham, NTT | 1 |
Lee, HK | 1 |
Woo, GH | 1 |
Kang, HG | 1 |
Ku, HO | 1 |
Sun, B | 2 |
Qu, Z | 3 |
Cheng, GL | 1 |
Yang, YW | 1 |
Miao, YF | 1 |
Chen, XG | 1 |
Zhou, XB | 1 |
Li, B | 5 |
Zhan, F | 1 |
Wang, X | 4 |
Yi, S | 1 |
He, P | 1 |
Wang, SY | 1 |
Zhang, CY | 1 |
Cai, GY | 1 |
Chen, XM | 1 |
He, W | 1 |
Qin, D | 1 |
Zhang, H | 2 |
Cheng, X | 1 |
Sun, J | 1 |
Hua, J | 1 |
Peng, S | 1 |
Ali, FEM | 1 |
Sayed, AM | 1 |
El-Bahrawy, AH | 1 |
Omar, ZMM | 1 |
Hassanein, EHM | 1 |
Cornell, LD | 1 |
Leung, N | 2 |
Abdel-Fattah, MM | 1 |
Elgendy, ANAM | 1 |
Mohamed, WR | 1 |
Dagneaux, L | 1 |
Limberg, AK | 1 |
Osmon, DR | 1 |
Berry, DJ | 1 |
Abdel, MP | 1 |
Rahdar, A | 1 |
Hasanein, P | 1 |
Bilal, M | 1 |
Beyzaei, H | 1 |
Kyzas, GZ | 1 |
Fan, X | 1 |
Gu, W | 1 |
Gao, Y | 1 |
Ma, N | 1 |
Fan, C | 1 |
Ci, X | 1 |
Taher, RF | 1 |
Raslan, MA | 1 |
Masoud, MA | 1 |
Nassar, MI | 1 |
Aboutabl, ME | 1 |
Ruiz-Ramirez, C | 1 |
Antaño-Martinez, AR | 1 |
Robles, J | 1 |
Gallegos-Corona, MA | 1 |
Gallegos-Reyes, MA | 1 |
Avila, EE | 1 |
Martinez-Alfaro, M | 1 |
Bencheikh, N | 1 |
Bouhrim, M | 1 |
Kharchoufa, L | 1 |
Al Kamaly, OM | 1 |
Mechchate, H | 1 |
Es-Safi, I | 1 |
Dahmani, A | 1 |
Ouahhoud, S | 1 |
El Assri, S | 1 |
Eto, B | 1 |
Bnouham, M | 1 |
Choukri, M | 1 |
Elachouri, M | 1 |
Kader, C | 1 |
Sunbul, M | 1 |
Das, YK | 1 |
Yarim, M | 1 |
Bedir, A | 1 |
Karaca, E | 1 |
Celikbilek, M | 1 |
Ozaras, R | 1 |
Casanova, AG | 1 |
Vicente-Vicente, L | 3 |
Hernández-Sánchez, MT | 1 |
Pescador, M | 2 |
Prieto, M | 1 |
Constance, JE | 2 |
Reith, D | 1 |
Ward, RM | 2 |
Balch, A | 1 |
Stockmann, C | 2 |
Korgenski, EK | 2 |
Thorell, EA | 1 |
Sherwin, CMT | 1 |
Wagoner, MP | 1 |
Yang, Y | 2 |
McDuffie, JE | 1 |
Klapczynski, M | 1 |
Buck, W | 1 |
Cheatham, L | 1 |
Eisinger, D | 1 |
Sace, F | 1 |
Lynch, KM | 1 |
Sonee, M | 1 |
Ma, JY | 1 |
Chen, Y | 2 |
Marshall, K | 1 |
Damour, M | 1 |
Stephen, L | 1 |
Dragan, YP | 1 |
Fikes, J | 1 |
Snook, S | 1 |
Kinter, LB | 1 |
Zamorskii, II | 1 |
Shchudrova, TS | 1 |
Lin'kova, NS | 1 |
Nichik, TE | 1 |
Khavinson, VK | 1 |
Uchino, H | 1 |
Fujishima, J | 1 |
Fukuoka, K | 1 |
Iwakiri, T | 1 |
Kamikuri, A | 1 |
Maeda, H | 1 |
Nakama, K | 1 |
Gorgulho, R | 1 |
Jacinto, R | 1 |
Lopes, SS | 1 |
Pereira, SA | 1 |
Tranfield, EM | 1 |
Martins, GG | 1 |
Gualda, EJ | 1 |
Derks, RJE | 1 |
Correia, AC | 1 |
Steenvoorden, E | 1 |
Pintado, P | 1 |
Mayboroda, OA | 1 |
Monteiro, EC | 1 |
Morello, J | 1 |
Hayward, RS | 1 |
Harding, J | 1 |
Molloy, R | 1 |
Land, L | 1 |
Longcroft-Neal, K | 1 |
Moore, D | 1 |
Ross, JDC | 1 |
Gebremichael, Y | 1 |
Lu, J | 1 |
Shankaran, H | 1 |
Helmlinger, G | 1 |
Mettetal, J | 1 |
Hallow, KM | 1 |
Berkovitch, M | 1 |
Shain, Y | 1 |
Kozer, E | 1 |
Goldman, M | 1 |
Abu-Kishk, I | 1 |
Sihra, N | 1 |
Aboelsoud, M | 1 |
Oliyide, A | 1 |
Counsell, A | 1 |
Gall, Z | 1 |
Peixoto, BC | 1 |
Contrera, GG | 1 |
Cieslinski, J | 1 |
Gasparetto, J | 1 |
Tuon, FF | 1 |
Brereton, CJ | 1 |
Lennon, D | 1 |
Browning, S | 1 |
Dunn, E | 1 |
Ferguson, JK | 1 |
Davis, JS | 1 |
Ma, YR | 1 |
Luo, X | 1 |
Wu, YF | 1 |
Zhang, T | 1 |
Zhang, F | 1 |
Zhang, GQ | 1 |
Wu, XA | 1 |
Stojiljkovic, N | 5 |
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Hagiwara, M | 1 |
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Fillastre, JP | 5 |
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Elliott, WC | 3 |
Houghton, DC | 6 |
Gilbert, DN | 7 |
Baines-Hunter, J | 2 |
Bennett, WM | 7 |
Bulger, RE | 2 |
Eknoyan, G | 1 |
Purcell, DJ | 1 |
Dobyan, DC | 2 |
Humes, HD | 2 |
Weinberg, JM | 2 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Differentiation of Acute Kidney Injury in Sepsis and Due to Nephrotoxic Antibiotic Treatment With Vancomycin and Gentamicin Based on Measurements of Specific miRNAs[NCT04991376] | 53 participants (Actual) | Observational | 2019-05-02 | Completed | |||
Pharmacokinetics of Tobramycin Administered at the Beginning of Intermittent Hemodialysis Session[NCT03904836] | Phase 1 | 11 participants (Actual) | Interventional | 2019-01-31 | Completed | ||
"Combination Treatment for Enterococcus Faecalis Bacteremia: a Prospective, Multicenter, Observational Study"[NCT04070820] | 500 participants (Anticipated) | Observational | 2019-09-01 | Recruiting | |||
Predicting Acute Kidney Injury in Infants Exposed to Nephrotoxic Drugs: A Big Data Approach to Predict NEOnatal Acute Kidney Injury in Newborns expoSed to nephroTOxic Drugs. (NeoAKI STOP)[NCT05851222] | 4,200 participants (Anticipated) | Observational | 2023-08-01 | Not yet recruiting | |||
Phase I Study Evaluating the Safety of Bevacizumab in Women With a History of Breast Cancer Suffering From Moderate to Severe Upper Extremity Lymphedema[NCT00318513] | Phase 1 | 35 participants | Interventional | Not yet recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
25 reviews available for gentamicin and Acute Kidney Failure
Article | Year |
---|---|
Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction.
Topics: Acute Kidney Injury; beta Catenin; Calcium; Gentamicins; Humans; Mitochondria; Pyrvinium Compounds; | 2022 |
Nephrotoxicity Related to Antibiotic-Loaded Spacers in a 2-Stage Revision for Periprosthetic Joint Infection.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Bone Cements; Gentamicins; Humans; Prosthesis-Related In | 2023 |
Acute Kidney Injury in Septic Patients Treated by Selected Nephrotoxic Antibiotic Agents-Pathophysiology and Biomarkers-A Review.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Biomarkers; Gentamicins; Humans; Kidney; MicroR | 2020 |
Adverse effects of a single dose of gentamicin in adults: a systematic review.
Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Bias; Dose-Response Relationship, Drug; Drug-Rela | 2018 |
Acute kidney injury during treatment with high-dose cloxacillin: a report of 23 cases and literature review.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin-C | 2018 |
Antioxidants. Do they have a place in the prevention or therapy of acute kidney injury?
Topics: Acute Kidney Injury; Animals; Antioxidants; Clinical Trials as Topic; Coronary Artery Bypass; Gentam | 2008 |
[Drug induced AKI].
Topics: Acute Kidney Injury; Analgesics; Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; An | 2010 |
Aminoglycoside use in cystic fibrosis: therapeutic strategies and toxicity.
Topics: Acute Kidney Injury; Aminoglycosides; Cystic Fibrosis; Dose-Response Relationship, Drug; Gentamicins | 2010 |
[Carnosine, carnosinase and kidney diseases].
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Carnosine; Diabetic N | 2012 |
[An effect of continuous and intermittent renal replacement therapy on antibiotic treatment in critically ill patients with sepsis - a practice-based perspective of vancomycin and gentamycin therapies].
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Critical Illness; Gentamicins; Humans; Renal Dialysis; S | 2012 |
Alterations of renal tubular cell metabolism in acute renal failure.
Topics: Acidosis, Renal Tubular; Acute Kidney Injury; Adenosine Diphosphate; Adenosine Monophosphate; Adenos | 1983 |
[Aminoglycoside nephropathy].
Topics: Acute Kidney Injury; Adult; Aminoglycosides; Ampicillin; Drug Synergism; Enzymes; Gentamicins; Glome | 1982 |
The effect of netilmicin and other aminoglycosides on renal function. A survey of the literature on the nephrotoxicity of netilmicin.
Topics: Acute Kidney Injury; Aminoglycosides; Animals; Dose-Response Relationship, Drug; Gentamicins; Glomer | 1980 |
Heat-shock proteins in animal models for acute renal failure.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Constriction; | 1995 |
Oxidant mechanisms in toxic acute renal failure.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Cyclosporine; Free Radicals; Gentamicins; Glyce | 1997 |
Oxidant mechanisms in toxic acute renal failure.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Cryoprotectiv | 1999 |
[Acute renal failure].
Topics: Acute Kidney Injury; Animals; Cytochrome P-450 Enzyme System; Gentamicins; Glycerol; Heme Oxygenase | 2002 |
Aminoglycoside nephrotoxicity: pathogenesis and prevention.
Topics: Acute Kidney Injury; Aminoglycosides; Gentamicins; Glomerular Filtration Rate; Humans; Kidney; Kidne | 1979 |
Antibiotics in the peri-operative period.
Topics: Acute Kidney Injury; Aminoglycosides; Anesthesia; Anti-Bacterial Agents; Bronchitis; Cephalosporins; | 1976 |
Antibiotic nephrotoxicity. A review of pathogenesis and prevention.
Topics: Acute Kidney Injury; Aminoglycosides; Animals; Anti-Bacterial Agents; Antifungal Agents; Cephalospor | 1975 |
[Antibiotics and the kidney].
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cephalosporins; Chloramphenicol; Gentamicins; Humans; Ka | 1975 |
Pathology and pathogenesis of nephrotoxic membrane damage.
Topics: Acute Kidney Injury; Animals; Cell Membrane; Cells, Cultured; Epithelium; Gentamicins; Kidney Tubule | 1985 |
Experimental models of nephrotoxic acute renal failure.
Topics: Acute Kidney Injury; Animals; Capillary Permeability; Cisplatin; Disease Models, Animal; Dogs; Genta | 1985 |
The management of bacteremic shock.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Burns; Catheterization; Cephaloridine; Cephalot | 1969 |
Practical use of penicillin, cephalosporin and aminoglycoside antibiotics.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cephalosp | 1972 |
6 trials available for gentamicin and Acute Kidney Failure
Article | Year |
---|---|
Immortalized canine adipose-derived mesenchymal stem cells alleviate gentamicin-induced acute kidney injury by inhibiting endoplasmic reticulum stress in mice and dogs.
Topics: Acute Kidney Injury; Animals; Apoptosis; Butylamines; Cells, Cultured; Culture Media; Dog Diseases; | 2021 |
Netilmicin versus tobramycin in multi-centre studies.
Topics: Acute Kidney Injury; Aged; Bacterial Infections; Clinical Trials as Topic; Ear Diseases; Female; Gen | 1984 |
Renal function following cardiopulmonary bypass surgery in children: a randomized comparison of the effects of gentamicin and cloxacillin with cephalothin.
Topics: Acute Kidney Injury; Cardiopulmonary Bypass; Cephalothin; Child; Cloxacillin; Gentamicins; Humans; P | 1983 |
Double-blind comparison of the nephrotoxicity and auditory toxicity of gentamicin and tobramycin.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Audiometry; Clinical Trials as Topic; Creatinine; Double | 1980 |
Cephalothin plus an aminoglycoside is more nephrotoxic than methicillin plus an aminoglycoside.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cephalothin; Clinical Trials as Topic; Double-Blind Meth | 1978 |
High dose frusemide in acute reversible intrinsic renal failure. A preliminary communication.
Topics: Acute Kidney Injury; Adult; Clinical Trials as Topic; Deafness; Furosemide; Gentamicins; Humans; Kan | 1974 |
448 other studies available for gentamicin and Acute Kidney Failure
Article | Year |
---|---|
Evaluation of symmetric dimethylarginine and Doppler ultrasonography in the diagnosis of gentamicin-induced acute kidney injury in dogs.
Topics: Acute Kidney Injury; Animals; Arginine; Dogs; Gentamicins; Ultrasonography, Doppler | 2022 |
Protective role of salicylic acid in gentamicin induced nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antioxidants; Body Weight; Catalase; Creatinine | 2021 |
Effect of salicylic acid supplementation on blood glucose, lipid profile and electrolyte homeostasis in gentamicin sulphate induced nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Blood Glucose; Body Weig | 2021 |
Oral Treatment with Angiotensin-(1-7) Attenuates the Kidney Injury Induced by Gentamicin in Wistar Rats.
Topics: Acute Kidney Injury; Administration, Oral; Angiotensin I; Animals; Drug Evaluation; Gentamicins; Mal | 2021 |
Exogenous glutathione protects against gentamicin-induced acute kidney injury by inhibiting NF-κB pathway, oxidative stress, and apoptosis and regulating PCNA.
Topics: Acute Kidney Injury; Animals; Apoptosis; Gentamicins; Glutathione; Kidney; NF-kappa B; Oxidative Str | 2023 |
Expression and 7-day time course of circulating microRNAs in septic patients treated with nephrotoxic antibiotic agents.
Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Circulating MicroRNA; Creatinine; Female; Gentami | 2022 |
Modulation of gentamicin-induced acute kidney injury by myo-inositol oxygenase via the ROS/ALOX-12/12-HETE/GPR31 signaling pathway.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Acute Kidney Injury; Animals; Creatinine; Cytokines; Gen | 2022 |
Antibacterial-associated acute kidney injury among older adults: A post-marketing surveillance study using the FDA adverse events reporting system.
Topics: Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Aged; Anti-Bacterial Agents; Bayes The | 2022 |
Protective effect of empagliflozin on gentamicin-induced acute renal injury via regulation of SIRT1/NF-κB signaling pathway.
Topics: Acute Kidney Injury; Animals; Benzhydryl Compounds; Gentamicins; Glucosides; Kidney; Male; NF-kappa | 2022 |
L-cysteine protective effects against platelet disaggregation and echinocyte occurrence in gentamicin-induced kidney injury.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Creatinine; Cysteine; Gentamicins; Kidney; Male | 2023 |
Nephroprotective effects of Helianthus annuus seeds extract in gentamicin induced nephrotoxic male mice.
Topics: Acute Kidney Injury; Animals; Antioxidants; Creatinine; Gentamicins; Helianthus; Kidney; Male; Mice; | 2022 |
Protective effect of inhibiting necroptosis on gentamicin-induced nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Apoptosis; Gentamicins; Inflammation; Necroptos | 2022 |
The
Topics: Acute Kidney Injury; Amomum; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; bcl-2-Assoc | 2022 |
Rivastigmine ameliorates gentamicin experimentally induced acute renal toxicity.
Topics: Acute Kidney Injury; Animals; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Kidney; | 2023 |
Rivastigmine ameliorates gentamicin experimentally induced acute renal toxicity.
Topics: Acute Kidney Injury; Animals; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Kidney; | 2023 |
Rivastigmine ameliorates gentamicin experimentally induced acute renal toxicity.
Topics: Acute Kidney Injury; Animals; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Kidney; | 2023 |
Rivastigmine ameliorates gentamicin experimentally induced acute renal toxicity.
Topics: Acute Kidney Injury; Animals; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Kidney; | 2023 |
Liraglutide ameliorates gentamicin-induced acute kidney injury in rats via PGC-1α- mediated mitochondrial biogenesis: Involvement of PKA/CREB and Notch/Hes-1 signaling pathways.
Topics: Acute Kidney Injury; Animals; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Prot | 2023 |
Liraglutide ameliorates gentamicin-induced acute kidney injury in rats via PGC-1α- mediated mitochondrial biogenesis: Involvement of PKA/CREB and Notch/Hes-1 signaling pathways.
Topics: Acute Kidney Injury; Animals; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Prot | 2023 |
Liraglutide ameliorates gentamicin-induced acute kidney injury in rats via PGC-1α- mediated mitochondrial biogenesis: Involvement of PKA/CREB and Notch/Hes-1 signaling pathways.
Topics: Acute Kidney Injury; Animals; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Prot | 2023 |
Liraglutide ameliorates gentamicin-induced acute kidney injury in rats via PGC-1α- mediated mitochondrial biogenesis: Involvement of PKA/CREB and Notch/Hes-1 signaling pathways.
Topics: Acute Kidney Injury; Animals; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Prot | 2023 |
Low nephron endowment increases susceptibility to renal stress and chronic kidney disease.
Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Humans; Hypertrophy; Infant, Premature; Kidney; M | 2023 |
Cochleotoxicity and acute kidney injury secondary to parenteral gentamicin administration in a dog.
Topics: Acute Kidney Injury; Animals; Dog Diseases; Dogs; Evoked Potentials, Auditory, Brain Stem; Gentamici | 2019 |
Rosuvastatin Attenuates acute nephrotoxicity through modulation of oxidative stress in Sprague Dawley rats.
Topics: Acute Kidney Injury; Animals; Biomarkers; Gentamicins; Hydroxymethylglutaryl-CoA Reductase Inhibitor | 2019 |
The protective role of estrogen and its receptors in gentamicin-induced acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Estradiol; Estrogen Receptor beta; Estrogens; Female; Fulvestrant; Gen | 2019 |
Nephron loss detected by MRI following neonatal acute kidney injury in rabbits.
Topics: Acute Kidney Injury; Animals; Animals, Newborn; Cations; Disease Models, Animal; Ferritins; Gentamic | 2020 |
Clindamycin, Gentamicin, and Risk of Clostridium difficile Infection and Acute Kidney Injury During Delivery Hospitalizations.
Topics: Acute Kidney Injury; Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Clindamycin; | 2020 |
Protective effect of Polygonatum sibiricum polysaccharides on gentamicin-induced acute kidney injury in rats via inhibiting p38 MAPK/ATF2 pathway.
Topics: Activating Transcription Factor 2; Acute Kidney Injury; Animals; Biomarkers; Biopsy; Blood Chemical | 2020 |
Impaired Tubular Reabsorption Is the Main Mechanism Explaining Increases in Urinary NGAL Excretion Following Acute Kidney Injury in Rats.
Topics: Acute Kidney Injury; Animals; Biomarkers; Cisplatin; Disease Models, Animal; Gentamicins; Kidney Tub | 2020 |
Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Endoplasmic Reticulum Stress; Gentamicins; Humans | 2020 |
Mapping vascular and glomerular pathology in a rabbit model of neonatal acute kidney injury using MRI.
Topics: Acute Kidney Injury; Animals; Animals, Newborn; Disease Models, Animal; Gentamicins; Indomethacin; K | 2020 |
Evaluation of 10 Urinary Biomarkers for Renal Safety With 5 Nephrotoxicants in Nonhuman Primates.
Topics: Acute Kidney Injury; Animals; Biomarkers; Cisplatin; Creatinine; Cystatin C; Gentamicins; Kidney; Li | 2020 |
Gentamicin-Induced Acute Kidney Injury in an Animal Model Involves Programmed Necrosis of the Collecting Duct.
Topics: Acute Kidney Injury; Animals; Cells, Cultured; Disease Models, Animal; Gentamicins; Imidazoles; Indo | 2020 |
Acute kidney failure after intra-articular use of gentamicin sponge.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Gentamicins; Hip Prosthesis; Humans; Male; Prosthe | 2020 |
Antibiotic treatment with one single dose of gentamicin at admittance in addition to a β-lactam antibiotic in the treatment of community-acquired bloodstream infection with sepsis.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Bacteremia; Bacteria; beta-Lactams; Community-Acqu | 2020 |
Pirfenidone attenuates gentamicin-induced acute kidney injury by inhibiting inflammasome-dependent NLRP3 pathway in rats.
Topics: Acute Kidney Injury; Animals; Body Weight; Chemokine CCL2; Gentamicins; Inflammasomes; Kidney Functi | 2020 |
Purified Sika deer antler protein attenuates GM-induced nephrotoxicity by activating Nrf2 pathway and inhibiting NF-κB pathway.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antlers; Apoptosis; Carrier Proteins; Deer; Gen | 2020 |
ACE2 activator diminazene aceturate exerts renoprotective effects in gentamicin-induced acute renal injury in rats.
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Body Weight; Cytokines; D | 2020 |
Identification of urinary microRNA biomarkers for
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Biomarkers; Disease Models, Animal; Female; Gen | 2020 |
Urinary microRNAs miR-15b and miR-30a as novel noninvasive biomarkers for gentamicin-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Biomarkers; Disease Models, Animal; Dogs; Gene Expression Regulation; | 2021 |
Glutamine alleviates the renal dysfunction associated with gentamicin-induced acute kidney injury in Sprague-Dawley rats.
Topics: Acute Kidney Injury; Animals; Gentamicins; Glutamine; Humans; Kidney; Male; Oxidative Stress; Rats; | 2022 |
Method used to establish a large animal model of drug-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Cisplatin; Disease Models, Animal; Gentamicins; Male; Swine; Swine, Mi | 2021 |
Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Blotting, Western; Creatinine; Diosmin; Gentamicins; Kelch-Like ECH-As | 2021 |
Myeloid bodies in acute tubular injury.
Topics: Acute Kidney Injury; Gentamicins; Humans; Kidney Tubules | 2021 |
Xanthenone, ACE2 activator, counteracted gentamicin-induced nephrotoxicity in rats: Impact on oxidative stress and ACE2/Ang-(1-7) signaling.
Topics: Acute Kidney Injury; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Gen | 2021 |
Acute Kidney Injury When Treating Periprosthetic Joint Infections After Total Knee Arthroplasties with Antibiotic-Loaded Spacers: Incidence, Risks, and Outcomes.
Topics: Acute Kidney Injury; Administration, Oral; Adult; Aged; Aged, 80 and over; Amphotericin B; Anti-Bact | 2021 |
Quercetin-loaded F127 nanomicelles: Antioxidant activity and protection against renal injury induced by gentamicin in rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Biomarkers; Blood Urea Nitrogen; Gentamicins; Glutathion | 2021 |
Daphnetin ameliorated GM-induced renal injury through the suppression of oxidative stress and apoptosis in mice.
Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Cell Line; Cell Survival; Epithelial Cells; G | 2021 |
HPLC-ESI/MS profiling, phytoconstituent isolation and evaluation of renal function, oxidative stress and inflammation in gentamicin-induced nephrotoxicity in rats of Ficus spragueana Mildbr. & Burret.
Topics: Acute Kidney Injury; Animals; Antioxidants; Chromatography, High Pressure Liquid; Disease Models, An | 2021 |
Correlation between urinary KIM-1 and kidney protein expression of p-ERK following damage in rats exposed to gentamicin or lead acetate.
Topics: Acute Kidney Injury; Animals; Calcium Channels; Cation Transport Proteins; Cell Adhesion Molecules; | 2021 |
The Nephroprotective Effect of
Topics: Acute Kidney Injury; Animals; Cytoprotection; Disease Models, Animal; Fruit; Gentamicins; Kidney; Pl | 2021 |
Telbivudine attenuates gentamicin-induced kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Cystatin C; Gentamicins; Glomerular Filtration Rate; Hepatitis B, Chro | 2017 |
Key role of oxidative stress in animal models of aminoglycoside nephrotoxicity revealed by a systematic analysis of the antioxidant-to-nephroprotective correlation.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Catalase; Disease Models, Animal; Gentamicins; | 2017 |
Risk of nonsteroidal anti-inflammatory drug-associated renal dysfunction among neonates diagnosed with patent ductus arteriosus and treated with gentamicin.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Case-Control St | 2017 |
Evaluation of Temporal Changes in Urine-based Metabolomic and Kidney Injury Markers to Detect Compound Induced Acute Kidney Tubular Toxicity in Beagle Dogs.
Topics: Acute Kidney Injury; Animals; Biomarkers; Dogs; Female; Gentamicins; Kidney Tubules; Male | 2017 |
Nephroprotective Effect of EDL Peptide at Acute Injury of Kidneys of Different Genesis.
Topics: Acute Kidney Injury; Animals; Animals, Outbred Strains; Antioxidants; Azotemia; Gentamicins; Kidney | 2017 |
Usefulness of urinary biomarkers for nephrotoxicity in cynomolgus monkeys treated with gentamicin, cisplatin, and puromycin aminonucleoside.
Topics: Acute Kidney Injury; Albuminuria; Animals; beta 2-Microglobulin; Biomarkers; Cisplatin; Clusterin; C | 2017 |
Usefulness of zebrafish larvae to evaluate drug-induced functional and morphological renal tubular alterations.
Topics: Acetaminophen; Acute Kidney Injury; Animals; Animals, Genetically Modified; Gentamicins; Inactivatio | 2018 |
Multiscale Mathematical Model of Drug-Induced Proximal Tubule Injury: Linking Urinary Biomarkers to Epithelial Cell Injury and Renal Dysfunction.
Topics: Acute Kidney Injury; Animals; Biomarkers; Cisplatin; Drug Development; Drug-Related Side Effects and | 2018 |
Hyperbaric oxygen treatment and nephrotoxicity induced by gentamicin in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Gentamicins; Hyperbaric Oxygenation; Kidney Fun | 2017 |
Seminal Vesicle Abscess-An Unusual Complication Following Vasectomy.
Topics: Abscess; Acute Kidney Injury; Adult; Anti-Bacterial Agents; Combined Modality Therapy; Delayed Diagn | 2018 |
Acute kidney injury in patients using low dose (3 mg/kg/day) of gentamicin under therapeutic dose monitoring.
Topics: Acute Kidney Injury; Biomarkers; Gentamicins; Humans; Sepsis | 2018 |
Is gentamicin safe and effective for severe community-acquired pneumonia? An 8-year retrospective cohort study.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Community-Acquired Infe | 2018 |
Alteration of renal excretion pathways in gentamicin-induced renal injury in rats.
Topics: Acute Kidney Injury; Animals; Antiporters; ATP Binding Cassette Transporter, Subfamily G, Member 2; | 2018 |
α-Tocopherol Reduces Morphological Changes and Oxidative Stress during Gentamicin-Induced Acute Renal Failure.
Topics: Acute Kidney Injury; alpha-Tocopherol; Animals; Antioxidants; Catalase; Gentamicins; Kidney Glomerul | 2018 |
Nephrotoxicity After the Treatment of Periprosthetic Joint Infection With Antibiotic-Loaded Cement Spacers.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis, Infectious; Arthropl | 2018 |
Renal safety of short-term empiric gentamicin therapy in aged patients.
Topics: Acute Kidney Injury; Age Factors; Aged; Aged, 80 and over; Aging; Anti-Bacterial Agents; Biomarkers; | 2018 |
Predictive performance of a gentamicin population pharmacokinetic model in two western populations of critically ill patients.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Area Under Curve; Critical Illness; Drug Administr | 2018 |
Acute Kidney Injury After Prophylactic Cefuroxime and Gentamicin in Patients Undergoing Primary Hip and Knee Arthroplasty-A Propensity Score-Matched Study.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; | 2018 |
Mechanisms Underlying Exacerbation of Osmotic Nephrosis Caused by Pre-existing Kidney Injury.
Topics: Acute Kidney Injury; Animals; Dextrans; Disease Models, Animal; Disease Progression; Female; Gentami | 2018 |
In vitro evaluation of biomarkers of nephrotoxicity through gene expression using gentamicin.
Topics: Acute Kidney Injury; Animal Use Alternatives; Anti-Bacterial Agents; Apoptosis; Biomarkers, Pharmaco | 2018 |
Risk Factors for Kidney Dysfunction With the Use of Gentamicin in Open Fracture Antibiotic Treatment.
Topics: Acute Kidney Injury; Antibiotic Prophylaxis; Case-Control Studies; Databases, Factual; Female; Fract | 2018 |
Birth weight, Apgar scores and gentamicin were associated with acute kidney injuries in VLBW neonates requiring treatment for patent ductus arteriosus.
Topics: Acute Kidney Injury; Apgar Score; Birth Weight; Ductus Arteriosus, Patent; Female; Gentamicins; Huma | 2019 |
The effect of short-course gentamicin therapy on kidney function in patients with bacteraemia-a retrospective cohort study.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Bacteremia; Denmark; Female; Gentam | 2018 |
The Protective Effect of Sika Deer Antler Protein on Gentamicin-Induced Nephrotoxicity in Vitro and in Vivo.
Topics: Acute Kidney Injury; Animals; Antioxidants; Antlers; Apoptosis; Blood Urea Nitrogen; Creatinine; Dee | 2018 |
Urinary biomarker evaluation for early detection of gentamycin-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Biomarkers; Blood Urea Nitrogen; Creatinine; Dogs; Early Diagnosis; Ge | 2019 |
Potential Association of Weight-Based Gentamicin with Increased Acute Kidney Injury in Urologic Prosthetic Surgery.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Body Weight; Gentamicins; Humans; Incidence; Male; | 2019 |
Troxerutin down-regulates KIM-1, modulates p38 MAPK signaling, and enhances renal regenerative capacity in a rat model of gentamycin-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Adhesion Molecules; Gentamicins; Humans; Hydroxyethylr | 2018 |
A multiplexed UPLC-MS/MS assay for the simultaneous measurement of urinary safety biomarkers of drug-induced kidney injury and phospholipidosis.
Topics: Acute Kidney Injury; Animals; Biomarkers; Chromatography, Liquid; Disease Models, Animal; Gentamicin | 2019 |
Potential protective effects of Dapagliflozin in gentamicin induced nephrotoxicity rat model via modulation of apoptosis associated miRNAs.
Topics: Acute Kidney Injury; Animals; Apoptosis; Benzhydryl Compounds; Disease Models, Animal; Gene Expressi | 2019 |
A novel preventive mechanism of gentamicin-induced nephrotoxicity by atorvastatin.
Topics: Acute Kidney Injury; Animals; Atorvastatin; Gentamicins; Kidney; Male; Oxidative Stress; Protective | 2019 |
Combinational effect of curcumin and metformin against gentamicin-induced nephrotoxicity: Involvement of antioxidative, anti-inflammatory and antiapoptotic pathway.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Curcumin; Drug Combinations; Gent | 2019 |
Study on therapeutic action of bone marrow derived mesenchymal stem cell combined with vitamin E against acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Blood Urea Nitrogen; Bone Marrow Cells; Cell | 2013 |
Neutrophil gelatinase-associated lipocalin, a sensitive urinary biomarker of acute kidney injury in dogs receiving gentamicin.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Blood Urea Nitrogen; Dogs; Enzyme-Li | 2013 |
Histone deacetylase inhibitor enhances recovery after AKI.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Fibrosis; Gentamicins; Histone Deacetylase 1; | 2013 |
Nephroprotective effect of GSK-3β inhibition by lithium ions and δ-opioid receptor agonist dalargin on gentamicin-induced nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Blotting, Western; Cations, Monovalent; Cell Death; Enkephalin, Leucin | 2013 |
JBP485 improves gentamicin-induced acute renal failure by regulating the expression and function of Oat1 and Oat3 in rats.
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Ar | 2013 |
Effects of Korean red ginseng extract on acute renal failure induced by gentamicin and pharmacokinetic changes by metformin in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Drug Interactions; Gentamicins; Ginsenosides; H | 2013 |
Is prophylactic Gentamicin associated with acute kidney injury in patients undergoing surgery for fractured neck of femur?
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Clostridioides difficile; Female; Femoral Neck Fractures | 2013 |
Ascorbic acid reduces gentamicin-induced nephrotoxicity in rats through the control of reactive oxygen species.
Topics: Acute Kidney Injury; Animals; Ascorbic Acid; Creatinine; Gentamicins; Hydrogen Peroxide; Kidney; Mal | 2014 |
Ethanolic extract of garlic for attenuation of gentamicin-induced nephrotoxicity in Wistar rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Creatinine; Disease Models | 2013 |
Antibiotic-associated complications following lower limb arthroplasty: a comparison of two prophylactic regimes.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; | 2014 |
Nephrotoxicity of gentamicin implants.
Topics: Abdominal Wall; Acute Kidney Injury; Anti-Bacterial Agents; Drug Implants; Escherichia coli Infectio | 2014 |
Peri-operative renal morbidity secondary to gentamicin and flucloxacillin chemoprophylaxis for hip and knee arthroplasty.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthrop | 2013 |
Antibiotic-related acute kidney injury in patients undergoing elective joint replacement.
Topics: Acute Kidney Injury; Aged; Antibiotic Prophylaxis; Arthroplasty, Replacement, Hip; Arthroplasty, Rep | 2014 |
Acute kidney injury following unselected emergency admission: role of the inflammatory response, medication and co-morbidity.
Topics: Academic Medical Centers; Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Amphotericin B; C-Rea | 2014 |
[Severe human parechovirus-3 sepsis in a 6-week-old infant].
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cefotaxime; Citrobacter freundii; Drug Therapy, Combinat | 2014 |
Protective effect of hydrogen sulfide on gentamicin-induced renal injury.
Topics: Acute Kidney Injury; Animals; Drug Evaluation, Preclinical; Gentamicins; Hydrogen Sulfide; Kidney; M | 2014 |
Increased Tbx1 expression may play a role via TGFβ-Smad2/3 signaling pathway in acute kidney injury induced by gentamicin.
Topics: Acute Kidney Injury; Animals; Apoptosis; Biomarkers; Blood Urea Nitrogen; Caspase 3; Disease Models, | 2014 |
Administration of BMSCs with muscone in rats with gentamicin-induced AKI improves their therapeutic efficacy.
Topics: Acute Kidney Injury; Administration, Intravenous; Analysis of Variance; Animals; Apoptosis; Blotting | 2014 |
Nephroprotective effect of catechin on gentamicin-induced experimental nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Catechin; Creatine; Female | 2015 |
Once-daily dosed gentamicin is more nephrotoxic than once-daily dosed tobramycin in clinically infected patients.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cohort Studies; Female; | 2014 |
Risk of AKI with gentamicin as surgical prophylaxis.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; | 2014 |
The seen and the unseen: clinical guidelines and cost-effective care.
Topics: Acute Kidney Injury; Antibiotic Prophylaxis; Clostridioides difficile; Enterocolitis, Pseudomembrano | 2014 |
Standard operating procedures for antibiotic therapy and the occurrence of acute kidney injury: a prospective, clinical, non-interventional, observational study.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Drug Administration Schedule; Female; Gentamicins; Guide | 2014 |
Identification of tubular injury microRNA biomarkers in urine: comparison of next-generation sequencing and qPCR-based profiling platforms.
Topics: Acute Kidney Injury; Animals; Biomarkers; Gene Expression Profiling; Gene Expression Regulation; Gen | 2014 |
Costus afer ker gawl leaves against gentamicin-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Body Weight; Costus; Creatinine; Drinking; Eating; Electrolytes; Genta | 2014 |
KIM-1 and NGAL as biomarkers of nephrotoxicity induced by gentamicin in rats.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Anti-Bacterial Agents; Biomarkers; Cell Adhesion | 2014 |
Renoprotective effect of red ginseng in gentamicin-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Proliferation; Drug Evaluation, Preclinical; Gentamici | 2014 |
Is single-dose prophylactic gentamicin associated with acute kidney injury in patients undergoing cardiac surgery? A matched-pair analysis.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Procedure | 2014 |
Efficacy and safety of high-dose gentamicin re-dosing in ICU patients receiving haemodialysis.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Bacterial Agents; Gentamicins; Humans; Intensive Care Units; | 2015 |
Acute kidney injury is independently associated with higher mortality after cardiac surgery.
Topics: Acute Kidney Injury; Aged; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Bacterial Agents; Ca | 2014 |
Sub-nephrotoxic cisplatin sensitizes rats to acute renal failure and increases urinary excretion of fumarylacetoacetase.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Biomarkers; Cisplatin; Disease Models, Animal; | 2015 |
Protective effects of curcumin on acute gentamicin-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antiox | 2015 |
Rapamycin protects against gentamicin-induced acute kidney injury via autophagy in mini-pig models.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Apoptosis; Autophagy; Disease Models, Animal; G | 2015 |
Low-dose Gentamicin for Uncomplicated Enterococcus faecalis Bacteremia May be Nephrotoxic in Children.
Topics: Acute Kidney Injury; Adolescent; Anti-Bacterial Agents; Bacteremia; Baltimore; Child; Child, Prescho | 2015 |
Editorial Commentary: Pediatric Acute Kidney Injury: Is the Addition of Gentamicin Worth the Risk?
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Bacteremia; Enterococcus faecalis; Gentamicins; Gram-Pos | 2015 |
Transcription profile of genes affected in response to pathological changes in drug-induced rat model of acute kidney injury.
Topics: Acute Kidney Injury; Animals; Biomarkers; Bone Morphogenetic Protein 7; Cell Adhesion Molecules; Dis | 2015 |
Thymoquinone Ameliorates Acute Renal Failure in Gentamicin-Treated Adult Male Rats.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Antioxidants; Benzoquinones; Blood Urea Nitroge | 2015 |
Acute Kidney Injury With Tobramycin-Impregnated Bone Cement Spacers in Prosthetic Joint Infections.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Repl | 2015 |
Flavocoxid attenuates gentamicin-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Catechin; Dose-Response Relationship, Drug; Dru | 2015 |
Kidney Regeneration in Adult Zebrafish by Gentamicin Induced Injury.
Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Injections, Intraperitoneal; Kidney; Male; Nephro | 2015 |
Tubular Injury Biomarkers to Detect Gentamicin-Induced Acute Kidney Injury in the Neonatal Intensive Care Unit.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Acute-Phase Proteins; Anti-Bacterial Agents; Asphyxia Ne | 2016 |
Acute Kidney Injury and Renal Recovery with the Use of Aminoglycosides: A Large Retrospective Study.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Aminoglycosides; Antineoplastic Agents; Case-Control S | 2015 |
A propensity-matched cohort study of vancomycin-associated nephrotoxicity in neonates.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bacteremia; Coh | 2016 |
No increased risk of acute kidney injury after a single dose of gentamicin in patients with sepsis.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Combina | 2016 |
MiR-21 is required for efficient kidney regeneration in fish.
Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Proliferation; Cyprinodontiformes; Gene Expression Reg | 2015 |
Comparison of the Protective Effects of Melatonin and Silymarin Against Gentamicin-Induced Nephrotoxicity in Rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Body Weight; Creatinine; Gentamicins; Glutathione; Kidne | 2016 |
Melatonin synergistically enhances protective effect of atorvastatin against gentamicin-induced nephrotoxicity in rat kidney.
Topics: Acute Kidney Injury; Animals; Atorvastatin; Creatinine; Drug Synergism; Gentamicins; Glutathione; Ki | 2016 |
Enhanced renoprotective effect of IGF-1 modified human umbilical cord-derived mesenchymal stem cells on gentamicin-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Antigens, Surface; Antioxidants; Apoptosis; Biomarkers; Cell Movement; | 2016 |
Antibiotic related acute kidney injury in patients treated for open fractures.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefazolin; F | 2016 |
Cardiotrophin-1 therapy prevents gentamicin-induced nephrotoxicity in rats.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Acute-Phase Proteins; Animals; Anti-Bacterial Agents; An | 2016 |
Atorvastatin improves renal organic anion transporter 3 and renal function in gentamicin-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Atorvastatin; Gentamicins; Kidney; Male; Organic Anion Transporters, S | 2016 |
Identification of urinary microRNA biomarkers for detection of gentamicin-induced acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Area Under Curve; Biopsy; Dose-Response Relationship, Drug; Gene Expre | 2016 |
Upregulation of MuRF1 and MAFbx participates to muscle wasting upon gentamicin-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Gentamicins; Insulin; Insulin-Like Growth Factor I; Muscle Proteins; M | 2016 |
Reduction in post-operative acute kidney injury following a change in antibiotic prophylaxis policy for orthopaedic surgery: an observational study.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Ba | 2016 |
Pinocembrin attenuates gentamicin-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Flavanones; Gentamicins; Male; Oxidative Stress | 2016 |
Effect of Different Times of Intraperitoneal Injections of Human Bone Marrow Mesenchymal Stem Cell Conditioned Medium on Gentamicin-Induced Acute Kidney Injury.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Bone Marrow Cells; Culture Media, Conditioned; | 2016 |
Priming prevent nephrotoxic acute renal failure through stimulation of antioxidant defense mechanism.
Topics: Acute Kidney Injury; Animals; Antioxidants; Cells, Cultured; Gentamicins; Kidney Tubules, Proximal; | 2016 |
Prophylactic Gentamicin Is Not Associated with Acute Kidney Injury in Patients with Open Fractures.
Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Female; Fractures, Open; | 2016 |
A retrospective study of acute kidney injury in hip arthroplasty patients receiving gentamicin and dicloxacillin.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; | 2016 |
The effect of aqueous leaf extract of Telfairia occidentalis (Cucurbitaceae) on gentamycin-induced renal damage.
Topics: Acute Kidney Injury; Animals; Cucurbitaceae; Gentamicins; Male; Plant Extracts; Plant Leaves; Rats; | 2017 |
[C1q/tumor necrosis factor related protein 6 (CTRP6) is involved in gentamicin-induced acute kidney injury in rats].
Topics: Acute Kidney Injury; Adipokines; Animals; Blood Urea Nitrogen; Caspases; Creatinine; Enzyme-Linked I | 2016 |
Effect of Lycopene and Rosmarinic Acid on Gentamicin Induced Renal Cortical Oxidative Stress, Apoptosis, and Autophagy in Adult Male Albino Rat.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antioxidants; Apoptosis; Autophagy; Blood Urea | 2017 |
Neutrophil gelatinase-associated lipocalin production negatively correlates with HK-2 cell impairment: Evaluation of NGAL as a marker of toxicity in HK-2 cells.
Topics: Acetaminophen; Acute Kidney Injury; Biomarkers; Cadmium; Cell Line; Cell Survival; Cisplatin; Gentam | 2017 |
Evaluation of KIM-1 and NGAL as Early Indicators for Assessment of Gentamycin-Induced Nephrotoxicity In Vivo and In Vitro.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Cell Adhesion Molecules; Cell Line; | 2016 |
Identifying High-Risk Medications Associated with Acute Kidney Injury in Critically Ill Patients: A Pharmacoepidemiologic Evaluation.
Topics: Acute Kidney Injury; Adolescent; Case-Control Studies; Child; Child, Preschool; Critical Illness; Dr | 2017 |
Acute Kidney Injury in Critically Ill Children - An Ominous Legacy.
Topics: Acute Kidney Injury; Child; Critical Illness; Gentamicins; Humans; Intensive Care Units, Pediatric | 2017 |
Study the therapeutic mechanism of Amomum compactum in gentamicin-induced acute kidney injury rat based on a back propagation neural network algorithm.
Topics: Acute Kidney Injury; Amomum; Animals; Anti-Bacterial Agents; Biomarkers; Chromatography, High Pressu | 2017 |
Moderate aerobic exercise on the recovery phase of gentamicin-induced acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Exercise Therapy; Gentamicins; Kidney; Kidney F | 2017 |
The protective effects of zinc in experimental gentamicin induced acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Creatinine; Gentamicins; Glutathione Peroxidase | 2016 |
Nephroprotective effect of Rudgea viburnoides (Cham.) Benth leaves on gentamicin-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Creatinine; Gentamicins; Glomerular Filtration | 2017 |
Should we stop using intravenous gentamicin in patients with cystic fibrosis?
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Case-Control Studies; Cystic Fibrosis; Gentamicins; Huma | 2008 |
Integrated pathway analysis of rat urine metabolic profiles and kidney transcriptomic profiles to elucidate the systems toxicology of model nephrotoxicants.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Biomarkers; Cisplatin; D | 2008 |
Cystic fibrosis, aminoglycoside treatment and acute renal failure: the not so gentle micin.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Contraindications; Cystic Fibrosis; Gentamicins; Humans; | 2009 |
Severity of gentamicin's nephrotoxic effect on patients with infective endocarditis: a prospective observational cohort study of 373 patients.
Topics: Acute Kidney Injury; Aged; Cohort Studies; Creatinine; Denmark; Endocarditis; Enterococcus; Female; | 2009 |
Comparative protective effect of N-acetyl cysteine and tetramethylpyrazine in rats with gentamicin nephrotoxicity.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antioxidants; Body Weight; Creatinine; Gentamicins; Ki | 2009 |
Protective effects of pentoxifylline treatment on gentamicin-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Creatinine; Gentamicins; M | 2009 |
Efficacy of the combination of N-acetylcysteine and desferrioxamine in the prevention and treatment of gentamicin-induced acute renal failure in male Wistar rats.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Deferoxamine; Drug Therapy, Combination; Free Radical | 2009 |
Effect of Momordica dioica Roxb on gentamicin model of acute renal failure.
Topics: Acute Kidney Injury; Animals; Antioxidants; Creatinine; Female; Gentamicins; Glutathione; Kidney; Ma | 2010 |
Increased urinary losses of carnitine and decreased intramitochondrial coenzyme A in gentamicin-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Blood Urea Nitrogen; Carnitine; Coenzyme A; Cr | 2010 |
Gentamicin-associated acute kidney injury.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cohort Studies; Critical Illnes | 2009 |
Dynamic response of blood vessel in acute renal failure.
Topics: Acute Kidney Injury; Animals; Antioxidants; Ascorbic Acid; Blood Vessels; Creatinine; Gentamicins; K | 2009 |
Expression of augmenter of liver regeneration in rats with gentamicin-induced acute renal failure and its protective effect on kidney.
Topics: Acute Kidney Injury; Animals; Cell Line; Cell Proliferation; Gentamicins; Injections; Kidney; Kidney | 2009 |
Aminoglycoside use in intensive care units and aminoglycoside nephrotoxicity. Comment letter 1.
Topics: Acute Kidney Injury; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Gentamicins; Humans; Intensiv | 2010 |
Aminoglycoside use in intensive care units and aminoglycoside nephrotoxicity. Comment letter 2.
Topics: Acute Kidney Injury; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Gentamicins; Humans; Intensiv | 2010 |
Intravenous cell therapy for acute renal failure with serum amyloid A protein-reprogrammed cells.
Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Line; Cell Proliferation; Cell Transplantation; Cispla | 2010 |
Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Critical Illness; Female; Filtration; Gentamicins; Hum | 2010 |
Minimizing the toxicity of aminoglycosides in cystic fibrosis.
Topics: Acute Kidney Injury; Aminoglycosides; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; DNA, | 2010 |
Acute kidney injury in non-critically ill children treated with aminoglycoside antibiotics in a tertiary healthcare centre: a retrospective cohort study.
Topics: Acute Kidney Injury; Amikacin; Anti-Bacterial Agents; Child; Child, Preschool; Cohort Studies; Femal | 2011 |
Cytoprotective effect of vitamin C against gentamicin-induced acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Cell Nucleus; Cyto | 2012 |
Rapid diagnosis and quantification of acute kidney injury using fluorescent ratio-metric determination of glomerular filtration rate in the rat.
Topics: Acute Kidney Injury; Algorithms; Animals; Data Interpretation, Statistical; Female; Fluorescein-5-is | 2010 |
Sub-nephrotoxic doses of gentamicin predispose animals to developing acute kidney injury and to excrete ganglioside M2 activator protein.
Topics: Acute Kidney Injury; Animals; Biomarkers; Disease Models, Animal; Dose-Response Relationship, Drug; | 2010 |
Intravenous microinjections of zebrafish larvae to study acute kidney injury.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Female; Gentamicins; Injections, Intravenous; | 2010 |
Protective effect of grape seed extract on gentamicin-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antioxidants; Blood Urea Nitrogen; Creatinine; | 2010 |
Urinary levels of regenerating islet-derived protein III β and gelsolin differentiate gentamicin from cisplatin-induced acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antigens, Neoplasm; Antineoplastic Agents; Biom | 2011 |
Distribution and amount of cathepsin B in gentamicin-induced acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Cathepsin B; Gene Expression Regulation; Gentamicins; Kidney; Protein | 2010 |
The protective effect of eugenol against gentamicin-induced nephrotoxicity and oxidative damage in rat kidney.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antioxidants; Eugenol; Free Radical Scavengers; | 2011 |
Comparative profile of commercially available urinary biomarkers in preclinical drug-induced kidney injury and recovery in rats.
Topics: Acute Kidney Injury; Animals; Apoptosis; Biomarkers; Cell Adhesion Molecules; Clusterin; Gentamicins | 2011 |
[Experimental study on antagonism of tetrandrine in acute renal injury induced by gentamicin in guinea pig].
Topics: Acetylglucosaminidase; Actins; Acute Kidney Injury; Animals; Benzylisoquinolines; Drug Antagonism; D | 2003 |
Preconditioning induced by gentamicin protects against acute kidney injury: the role of prostaglandins but not nitric oxide.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Diclofenac; Gentamicins; Male; NG-Nit | 2011 |
Evaluation of efficacy of vitamin E and N-acetyl cysteine in gentamicin-induced nephrotoxicity in rats.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antioxidants; Drug Evaluation, | 2011 |
Gentamicin and acute kidney injury requiring renal replacement therapy in the context of a restrictive antibiotic policy.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Clostridium Infections; Gentamicins; Humans; Incidence; | 2011 |
Acute renal failure after topical fortified gentamicin and vancomycin eyedrops.
Topics: Acute Kidney Injury; Administration, Topical; Aged; Anti-Bacterial Agents; Endophthalmitis; Female; | 2011 |
A simple method of staging AKI in children.
Topics: Acute Kidney Injury; Amikacin; Anti-Bacterial Agents; Female; Gentamicins; Humans; Male; Tobramycin | 2011 |
Comparison of the course of biomarker changes and kidney injury in a rat model of drug-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; beta 2-Microglobulin; Biomarkers; Blood Urea Nitrogen; Calbindins; Cel | 2011 |
Floral extract of Tecoma stans: a potent inhibitor of gentamicin-induced nephrotoxicity in vivo.
Topics: Acute Kidney Injury; Animals; Bignoniaceae; Creatinine; Female; Flowers; Gentamicins; Humans; Male; | 2011 |
Nephroprotective activity of Macrothelypteris oligophlebia rhizomes ethanol extract.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antioxidants; Dose-Response Relationship, Drug; | 2012 |
Simvastatin ameliorates gentamicin-induced renal injury in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antioxidants; Creatinine; Gentamicins; Hydroxym | 2011 |
Nephroprotective effect of Croton zambesicus root extract against gentimicin-induced kidney injury.
Topics: Acute Kidney Injury; Animals; Antioxidants; Biomarkers; Chlorides; Creatinine; Croton; Dogs; Female; | 2011 |
Urinary vanin-1 as a novel biomarker for early detection of drug-induced acute kidney injury.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Amidohydrolases; Animals; beta-N-Acetyl-Galactosaminidase | 2012 |
Beneficial effects of calcium oral coadministration in gentamicin-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Calcium; Dietary Supplements; Disease Models, An | 2012 |
Protective effects of N-acetylcysteine amide (NACA) on gentamicin-induced apoptosis in LLC-PK1 cells.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Weste | 2012 |
Gentamicin pharmacokinetics during continuous venovenous hemofiltration in critically ill septic patients.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Infective Agents; Critical Illness; Drug Monitoring; Female; | 2012 |
Plasmid pUDK-HGF encoding human hepatocyte growth factor gene attenuates gentamicin-induced kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Apoptosis; Fibrosis; Gene Transfer Techniques; | 2013 |
Expression, circulation, and excretion profile of microRNA-21, -155, and -18a following acute kidney injury.
Topics: Acute Kidney Injury; Algorithms; Animals; Case-Control Studies; Gentamicins; Humans; MicroRNAs; Poly | 2012 |
A modified model of gentamicin induced renal failure in rats: toxicological effects of the iodinated X-ray contrast media ioversol and potential usefulness for toxicological evaluation of iodinated X-ray contrast media.
Topics: Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Dose-Response Relationship, Dr | 2013 |
Nephroprotective activity of Solanum xanthocarpum fruit extract against gentamicin-induced nephrotoxicity and renal dysfunction in experimental rodents.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antioxidants; Creatinine; Female; Free Radical | 2012 |
Renal protective effect of hesperidin on gentamicin-induced acute nephrotoxicity in male Wistar albino rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Creatinine; Gentamicins; Glutathione; Glutathione Peroxi | 2012 |
Is prophylactic Gentamicin associated with acute kidney injury in patients undergoing surgery for fractured neck of femur?
Topics: Acute Kidney Injury; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Cohort Stud | 2012 |
Mechanism-based urinary biomarkers to identify the potential for aminoglycoside-induced nephrotoxicity in premature neonates: a proof-of-concept study.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Acute-Phase Proteins; Aminoglycosides; Anti-Bacterial Ag | 2012 |
[Antimicrobial dosing in critically ill patients requiring renal replacement therapy - maximize efficacy and minimize toxicity!].
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Critical Illness; Gentamicins; Humans; Renal Dialysis; S | 2012 |
Bone marrow-derived mesenchymal stem cells repaired but did not prevent gentamicin-induced acute kidney injury through paracrine effects in rats.
Topics: Acute Kidney Injury; Animals; Bone Marrow Cells; Culture Media, Conditioned; Cytokines; Exosomes; Fe | 2012 |
In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury.
Topics: Acute Kidney Injury; Animals; Gentamicins; Glutathione; Ischemia; Kidney; Kidney Tubules, Distal; Ki | 2013 |
Hypoxia-inducible factor activation protects the kidney from gentamicin-induced acute injury.
Topics: Acute Kidney Injury; Amino Acids, Dicarboxylic; Animals; Apoptosis; Caspase 3; Caspase 9; Cells, Cul | 2012 |
Effects of obesity and sex on antimicrobial pharmacokinetics and acute kidney injury: validation of a preclinical model.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Anti-Bacterial Agents; Cell Adhesion Molecules; | 2013 |
Pomegranate extract attenuates gentamicin-induced nephrotoxicity in rats by reducing oxidative stress.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Biopsy, Needle; Chi-Square Distribution; Disease | 2013 |
Renal impairment after high-dose flucloxacillin and single-dose gentamicin prophylaxis in patients undergoing elective hip and knee replacement.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; | 2013 |
Increased urinary excretion of albumin, hemopexin, transferrin and VDBP correlates with chronic sensitization to gentamicin nephrotoxicity in rats.
Topics: Acute Kidney Injury; Albuminuria; Animals; Anti-Bacterial Agents; Biomarkers; Disease Susceptibility | 2013 |
Acute renal failure potentiates methylmalonate-induced oxidative stress in brain and kidney of rats.
Topics: Acute Kidney Injury; Amino Acid Metabolism, Inborn Errors; Animals; Catalase; Cerebral Cortex; Creat | 2013 |
Protective effect of montelukast which is cysteinyl-leukotriene receptor antagonist on gentamicin-induced nephrotoxicity and oxidative damage in rat kidney.
Topics: Acetates; Acute Kidney Injury; Animals; Anti-Bacterial Agents; Cyclopropanes; Drug Evaluation, Precl | 2013 |
Acute renal failure after local gentamicin treatment in an infected total knee arthroplasty.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee | 2002 |
The effect of treatment with gum Arabic on gentamicin nephrotoxicity in rats: a preliminary study.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Biomarkers; Cellulose; Creatinine; Disease Mode | 2003 |
Acute renal failure and cystic fibrosis.
Topics: Acute Kidney Injury; Ceftazidime; Cefuroxime; Child; Cystic Fibrosis; Drug Therapy, Combination; Gen | 2003 |
Protective effects of glycyrrhizin on gentamicin-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Anti-Bacterial Agents; Aquaporin 2; Aquaporin 6; | 2003 |
Study of serum and tissues angiotensin converting enzyme (ACE) activity in rat with gentamicin induced renal toxicity.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Biomarkers; Biopsy, Needle; Chromatography, High | 2003 |
Effect of Aerva lanata on cisplatin and gentamicin models of acute renal failure.
Topics: Acute Kidney Injury; Amaranthaceae; Animals; Antioxidants; Cisplatin; Dose-Response Relationship, Dr | 2004 |
Plasma protein extravasation and vascular endothelial growth factor expression with endothelial nitric oxide synthase induction in gentamicin-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Blood Proteins; Blotting, Western; Capillary Pe | 2004 |
Evaluation of factors to decrease bioavailability of cyclosporin A in rats with gentamicin-induced acute renal failure.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Area Under Curve; Aryl Hydrocarbon Hydroxylases; | 2004 |
Acute renal failure in zebrafish: a novel system to study a complex disease.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Disease Model | 2005 |
Role of the renin-angiotensin system on the parathyroid hormone-related protein overexpression induced by nephrotoxic acute renal failure in the rat.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Line; En | 2005 |
Flavonoid of Drynaria fortunei protects against acute renal failure.
Topics: Acute Kidney Injury; Animals; Creatinine; Disease Models, Animal; Gentamicins; Guinea Pigs; Kidney T | 2005 |
Effect of Cassia auriculata Linn. root extract on cisplatin and gentamicin-induced renal injury.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Cassia; Cisplatin; Creatinine; Dose-Response Rel | 2005 |
Regression of long standing anorexia nervosa following acute renal failure caused by gentamicin intoxication.
Topics: Acute Kidney Injury; Adult; Anorexia Nervosa; Anti-Bacterial Agents; Female; Gentamicins; Humans; Pn | 2005 |
Aminoglycosides in intermittent hemodialysis: pharmacokinetics with individual dosing.
Topics: Acute Kidney Injury; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Comorbidity; Fema | 2006 |
Kallikrein/kinin protects against gentamicin-induced nephrotoxicity by inhibition of inflammation and apoptosis.
Topics: Acute Kidney Injury; Adenoviridae; Animals; Apoptosis; Chemokine CCL2; Disease Models, Animal; Enzym | 2006 |
Effect of Spirulina, a blue green algae, on gentamicin-induced oxidative stress and renal dysfunction in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Bacterial Proteins; Female; Gentamicins; Kidney | 2006 |
[Perineal erythema, distal cyanosis and sepsis in an adult woman].
Topics: Acute Kidney Injury; Adult; Bacteremia; Cefotaxime; Cellulitis; Clindamycin; Combined Modality Thera | 2006 |
[Changes of angiotensin converting enzyme activity in rats with gentamicin-induced acute renal failure].
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Gentamicins; Peptidyl-Dipeptidase A; Rats | 2006 |
Protective role of aminoguanidine on gentamicin-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Guanidines; Rats; Rats, Wistar | 2006 |
CR5/20--Acute renal failure in a child with cystic fibrosis awaiting lung transplantation--a good outcome after all.
Topics: Acute Kidney Injury; Adolescent; Anti-Bacterial Agents; Ceftazidime; Cystic Fibrosis; Female; Follow | 2006 |
[Effect of amber acid on the kidney function in gentamycin-induced nephropathy in white rats].
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Gentamicins; Glomerular Filtration Rate; Inject | 2006 |
Immunohistochemical study on caveolin-1alpha in regenerating process of tubular cells in gentamicin-induced acute tubular injury in rats.
Topics: Acute Kidney Injury; Animals; Blotting, Western; Caveolae; Caveolin 1; Caveolin 2; Cell Cycle; ErbB | 2007 |
Subclinical kidney injury incites endotoxin hyperresponsiveness.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Endotoxins; Gentamicins; Gram-Negative Bacteria | 2007 |
Role of tissue kallikrein in prevention and recovery of gentamicin-induced renal injury.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Apoptosis; Blood Pressure; Blood Urea Nitrogen; | 2008 |
Parenteral administration of gentamicin in renal failure: patients undergoing intermittent haemodialysis.
Topics: Acute Kidney Injury; Adult; Biological Assay; Creatine; Female; Gentamicins; Humans; In Vitro Techni | 1967 |
Some recent pharmacological findings with nitrendipine.
Topics: Acute Kidney Injury; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel | 1984 |
Effect of some simple manoeuvres on the course of acute renal failure after gentamycin treatment in rats.
Topics: Acute Kidney Injury; Animals; Bicarbonates; Body Weight; Creatinine; Drinking; Eating; Female; Fluid | 1984 |
Gentamicin-induced nephrotoxicity: a cell biology approach.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Cell Fractionation; gamma-Glutamyltransferase; | 1980 |
[Studies on experimental renal damage in rats. II. beta 2-microglobulin: purification, radioimmunoassay, and urine and serum levels in tubular nephropathy].
Topics: Acute Kidney Injury; Animals; beta 2-Microglobulin; Beta-Globulins; Cephaloridine; Female; Gentamici | 1982 |
Gentamicin nephrotoxicity. I. Degree and permanence of acquired insensitivity.
Topics: Acute Kidney Injury; Animals; Gentamicins; Inulin; Kidney; Kidney Cortex; Male; Necrosis; Niacinamid | 1982 |
Endothelial characteristics of glomerular capillaries in normal, mercuric chloride-induced, and gentamicin-induced acute renal failure in the rat.
Topics: Acute Kidney Injury; Animals; Capillaries; Cytoplasm; Endothelium; Gentamicins; Kidney Glomerulus; M | 1983 |
The renin-angiotensin system in aminoglycoside-induced acute renal failure.
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; G | 1982 |
Myeloid bodies in drug-induced acute tubular necrosis.
Topics: Acute Kidney Injury; Adult; Chromium; Epithelium; Female; Gentamicins; Humans; Inclusion Bodies; Kid | 1983 |
The role of prostaglandins in gentamicin-induced nephrotoxicity in the dog.
Topics: Acute Kidney Injury; Animals; Dogs; Female; Gentamicins; Kidney Concentrating Ability; Prostaglandin | 1983 |
Aminoglycoside in advanced renal failure.
Topics: Acute Kidney Injury; Adolescent; Adult; Child; Child, Preschool; Escherichia coli Infections; Female | 1984 |
Nephrotoxicity of lysine and of a single dose of aminoglycoside in rats given lysine.
Topics: Acute Kidney Injury; Aminoglycosides; Animals; Blood Flow Velocity; Blood Pressure; Drug Synergism; | 1984 |
Changes in tissue calcium content during gentamicin acute renal failure.
Topics: Acute Kidney Injury; Animals; Calcium; Creatinine; Gentamicins; Kidney Cortex; Rats; Rats, Inbred St | 1984 |
[Studies on the nephrotoxicity of aminoglycoside antibiotics and protection from these effects. (1). Nephrotoxicity of gentamicin and mercuric chloride].
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Enzymes; Gentamicins; Kidney; Kidney Tubular Necr | 1984 |
[Studies on the nephrotoxicity of aminoglycoside antibiotics and protection from these effects. (2). Protective effect of latamoxef against gentamicin nephrotoxicity].
Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Gen | 1984 |
The renal concentrating defect after gentamicin administration in the rat.
Topics: Acute Kidney Injury; Animals; Dinoprostone; Gentamicins; Kidney Concentrating Ability; Kidney Medull | 1983 |
Role of tubular obstruction in acute renal failure due to gentamicin.
Topics: Acute Kidney Injury; Animals; Constriction, Pathologic; Gentamicins; Glomerular Filtration Rate; Kid | 1983 |
Cortical and papillary absorptive defects in gentamicin nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Gentamicins; Kidney; Kidney Cortex; Kidney Medulla; Polyuria; Rats; Ra | 1983 |
Renal and hepatic function in rats treated with cyclosporin A in combination with gentamicin or cephalosporin antibiotics.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Blood Proteins; Cephalosporins; Chemical and Dr | 1983 |
Calcium is a competitive inhibitor of gentamicin-renal membrane binding interactions and dietary calcium supplementation protects against gentamicin nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Basement Membrane; Binding, Competitive; Calcium; Cations, Divalent; G | 1984 |
Protection by selenium against gentamicin-induced acute renal damage in the rat.
Topics: Acid Phosphatase; Acute Kidney Injury; Alkaline Phosphatase; Animals; Gentamicins; Glucuronidase; Gl | 1984 |
Serum gentamicin concentrations during intratracheal administration.
Topics: Acute Kidney Injury; Adult; Female; Gentamicins; Humans; Intubation, Intratracheal; Kidney Failure, | 1984 |
Enhancement of gentamicin nephrotoxicity by magnesium depletion in the rat.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Gentamicins; Kidney; Magnesium Defici | 1984 |
Effect of duration of diabetes on the protection observed in the diabetic rat against gentamicin-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Body Weight; Diabetes Mellitus, Experimental; Drinking; Feeding Behavi | 1984 |
The morphology of the renal microvasculature in glycerol- and gentamicin-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Creatinine; Gentamicins; Glycerol; Kidney Cortex; Kidney Glomerulus; M | 1983 |
Gentamicin increases renal susceptibility to an acute ischemic insult.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Disease Susceptibility; Electrolytes; | 1983 |
Urinary myelin figures in gentamicin. Treated vs. ischemic kidneys.
Topics: Acute Kidney Injury; Animals; Constriction; Disease Models, Animal; Dogs; Gentamicins; Ischemia; Kid | 1983 |
Features of gentamicin nephrotoxicity and effect of concurrent cephalothin in the rat.
Topics: Acute Kidney Injury; Animals; Cephalothin; Gentamicins; Glomerular Filtration Rate; Kidney; Kidney C | 1983 |
Current patterns of acute renal failure.
Topics: Acute Kidney Injury; Adult; Aged; Colistin; Contrast Media; Gentamicins; Hemoglobinuria; Humans; Mal | 1981 |
Cefoxitin-associated renal failure.
Topics: Acute Kidney Injury; Aged; Aminoglycosides; Arthritis, Rheumatoid; Cefoxitin; Creatinine; Escherichi | 1981 |
The pathology of acute renal failure due to interstitial nephritis in man with comments on the role of interstitial inflammation and sex in gentamicin nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Creatinine; Female; Fluorescent Antibody Technique; Gentamicins; Human | 1982 |
Rebound gentamicin levels after hemodialysis.
Topics: Acute Kidney Injury; Adult; Female; Gentamicins; Humans; Male; Middle Aged; Renal Dialysis | 1982 |
Complete protection from gentamicin-induced acute renal failure in the diabetes mellitus rat.
Topics: Acute Kidney Injury; Animals; Diabetes Insipidus; Diabetes Mellitus, Experimental; Female; Gentamici | 1982 |
Gentamicin nephrotoxicity. II. Definition of conditions necessary to induce acquired insensitivity.
Topics: Acute Kidney Injury; Animals; Gentamicins; Kidney Cortex; Kidney Tubules; Male; Necrosis; Rats; Rats | 1982 |
Effect of potassium depletion on tubular morphology in gentamicin-induced acute renal failure in dogs.
Topics: Acute Kidney Injury; Animals; Creatinine; Diet; Dogs; Gentamicins; Kidney Cortex; Kidney Tubules; Ki | 1982 |
[Clinical evaluation of urinary n-acetyl-beta-d-glucosaminidase activity in patients treated with aminoglycosides].
Topics: Acetylglucosaminidase; Acute Kidney Injury; Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial | 1982 |
Severe nephrotoxicity: a probable complication of cis-dichlorodiammineplatinum (II) and cephalothin-gentamicin therapy.
Topics: Acute Kidney Injury; Blood Urea Nitrogen; Carbenicillin; Cephalothin; Choriocarcinoma; Cisplatin; Cr | 1982 |
[Nephro- and ototoxicity of aminoglycoside-antibiotics, with special reference to gentamicin (author's transl)].
Topics: Acute Kidney Injury; Aminoglycosides; Dose-Response Relationship, Drug; Drug Interactions; Gentamici | 1981 |
Experimental evidence of increased ipsilateral gentamicin nephrotoxicity after unilateral ureteral obstruction.
Topics: Acute Kidney Injury; Animals; Gentamicins; Inulin; Kidney Function Tests; Male; Rats; Ureteral Obstr | 1981 |
Treatment of a patient with impaired renal function with gentamicin-PMMA-beads.
Topics: Acute Kidney Injury; Aged; Female; Gentamicins; Hip Prosthesis; Humans; Surgical Wound Infection | 1981 |
Gentamicin-induced acute renal failure in the rat. Effect of dehydration, DOCA-saline and furosemide.
Topics: Acute Kidney Injury; Aminoglycosides; Animals; Blood Pressure; Creatinine; Dehydration; Desoxycortic | 1981 |
Recovery without a diuresis after protracted acute tubular necrosis.
Topics: Acute Kidney Injury; Cephalosporins; Cephapirin; Diuresis; Female; Gentamicins; Humans; Kidney Tubul | 1980 |
The safety of cefuroxime and gentamicin in patients with reduced renal function.
Topics: Acute Kidney Injury; Adult; Aged; Bacteriuria; Cefuroxime; Cephalosporins; Drug Therapy, Combination | 1980 |
The mechanism of the decline in glomerular filtration rate in gentamicin-induced acute renal failure in the rat.
Topics: Acute Kidney Injury; Animals; Body Weight; Gentamicins; Glomerular Filtration Rate; Hydrostatic Pres | 1980 |
Clinical nephrotoxicity of tobramycin and gentamicin. A prospective study.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Creatinine; Female; Gentamicins; Humans; Male; Middle Ag | 1980 |
Pathogenesis of renal failure due to aminoglycosides and contrast media used in roentgenography.
Topics: Acute Kidney Injury; Aminoglycosides; Animals; Contrast Media; Dogs; Gentamicins; Humans; Kidney Tub | 1980 |
Renal function in Fischer 344 rats with chronic renal impairment after administration of enflurane and gentamicin.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Body Weight; Chronic Disease; Creatinine; Enflura | 1980 |
In vivo inactivation of gentamicin by carbenicillin and ticarcillin.
Topics: Acute Kidney Injury; Biological Availability; Candidiasis; Carbenicillin; Drug Interactions; Drug Th | 1980 |
Mechanism of gentamicin nephrotoxicity in rats and the protective effect of zinc-induced metallothionein synthesis.
Topics: Acute Kidney Injury; Animals; DNA; Free Radicals; Gentamicins; Hydroxyl Radical; In Vitro Techniques | 1994 |
Induction and intracellular localization of 90-kilodalton heat-shock protein in rat kidneys with acute gentamicin nephropathy.
Topics: Acute Kidney Injury; Animals; Cell Nucleolus; Disease Models, Animal; Electrophoresis, Polyacrylamid | 1995 |
Comparative effects of low- and high-osmolar contrast media on the renal function during early degenerative gentamicin-induced nephropathy in rats.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Creatinine; Diatrizoate; Gentamicins; Glomerula | 1995 |
Decreased urine output after surgery in a neonate.
Topics: Acute Kidney Injury; Adult; Drug Therapy, Combination; Female; Gentamicins; Humans; Hydrocephalus; I | 1994 |
Protective effects of KW-3902, a novel adenosine A1-receptor antagonist, against gentamicin-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Disease Models, Animal; Furosemide; Gentamicins; | 1994 |
[Lipid peroxidation and tubular disorder in experimental acute renal failure-enzymochemical study in the rat kidney].
Topics: Acute Kidney Injury; Animals; Gentamicins; Glutathione; Glutathione Peroxidase; Kidney; Kidney Tubul | 1994 |
Roles of hemodynamic and tubular factors in gentamicin-mediated nephropathy.
Topics: Acute Kidney Injury; Animals; Desoxycorticosterone; Fluid Therapy; Free Radical Scavengers; Gentamic | 1994 |
Effects of gentamicin on glomerular renin release.
Topics: Acute Kidney Injury; Animals; Calcium; Gentamicins; In Vitro Techniques; Kidney Glomerulus; Male; Ra | 1994 |
Effect of sex hormones on gentamicin-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Castration; Creatinine; Estrogens; Female; Gentamicins; Kidney; Male; | 1993 |
[An experimental study on the pathogenetic role of acquired resistance to acute renal failure--Enzymochemical investigation].
Topics: Acute Kidney Injury; Animals; Drug Resistance; Gentamicins; Kidney; Male; Phospholipases; Phospholip | 1996 |
Glomerular angiotensin II receptors in gentamicin-induced renal failure in the rat.
Topics: Acute Kidney Injury; Analysis of Variance; Angiotensin II; Animals; Anti-Bacterial Agents; Creatinin | 1995 |
Vibrio cholerae 0139 diarrhea and acute renal failure in a three-day-old infant.
Topics: Acute Kidney Injury; Ampicillin; Child, Preschool; Cholera; Colistin; Diarrhea; Disease Outbreaks; D | 1995 |
Estimation of arcuate artery resistive index as a diagnostic tool for aminoglycoside-induced acute renal failure in dogs.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Arteries; Creatinine; Dog Diseases; Dogs; Femal | 1996 |
Protective effect of human ulinastatin against gentamicin-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Creatine; Gentamicins; Glycoproteins; Humans; Kidney; Male; Rats; Rats | 1996 |
Acute renal failure in cardiac surgical patients, potentiated by gentamicin and calcium.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Antibiotic Prophylaxis; Calcium; Cardiopulmonary Bypass; | 1996 |
Acute renal failure potentiated by gentamicin and calcium.
Topics: Acute Kidney Injury; Calcium; Critical Illness; Drug Interactions; Gentamicins; Humans | 1997 |
[Obstructive renal insufficiency caused by amoxicillin crystalluria].
Topics: Acute Kidney Injury; Aged; Amoxicillin; Crystallization; Drug Therapy, Combination; Encephalitis; Fe | 1997 |
[Experimental study on effect of Cordyceps sinensis in ameliorating aminoglycoside induced nephrotoxicity].
Topics: Acute Kidney Injury; Animals; Ascomycota; Drugs, Chinese Herbal; Female; Gentamicins; Humans; Male; | 1996 |
Kidney ectopeptidases in gentamicin and mercuric chloride-induced acute renal failure.
Topics: Acute Kidney Injury; Aminopeptidases; Animals; CD13 Antigens; Creatinine; Dipeptidyl Peptidase 4; Ex | 1998 |
Increased renal glomerular endothelin-1 release in gentamicin-induced nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Creatinine; Culture Techniques; Endothelin-1; Female; Gentamicins; Kid | 1999 |
Factors that affect absorption behavior of cyclosporin a in gentamicin-induced acute renal failure in rats.
Topics: Absorption; Acute Kidney Injury; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, | 2000 |
Syndrome of hypokalemic metabolic alkalosis and hypomagnesemia associated with gentamicin therapy: case reports.
Topics: Acute Kidney Injury; Adult; Alkalosis; Anti-Bacterial Agents; Cross Infection; Dose-Response Relatio | 2000 |
[Effect of KW-3902, a selective adenosine A1-receptor antagonist, on accumulation of gentamicin in the proximal renal tubules in rats].
Topics: Acute Kidney Injury; Adenosine; Animals; Anti-Bacterial Agents; Gentamicins; Kidney Tubules, Proxima | 2000 |
[Methodology for designing pathological models of acute renal failure].
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Dogs; Female; Gentamicins; Glycerol; Kidney; M | 1998 |
Renal osteopontin protein and mRNA upregulation during acute nephrotoxicity in the rat.
Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Mercuric Chloride; Osteopontin; Rats; Rats, Wista | 2001 |
Melatonin protects against gentamicin-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Glutathione; Kidney; Malondialdehyde; Melatonin; | 2002 |
[Influence of dose regimen on gentamycin nephrotoxicity in rats].
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Drug Administration Schedule; Gentamicins; Male | 2001 |
Letter: Interaction between gentamicin and cephalothin as cause of acute renal failure.
Topics: Acute Kidney Injury; Adult; Cephalothin; Drug Synergism; Female; Gentamicins; Humans | 1976 |
Nephrotoxicity of methicillin/aminoglycoside.
Topics: Acute Kidney Injury; Drug Synergism; Drug Therapy, Combination; Gentamicins; Humans; Methicillin | 1978 |
Managing the complications of plasma cell myeloma.
Topics: Acute Kidney Injury; Bacterial Infections; Blood Urea Nitrogen; Blood Viscosity; Bone Neoplasms; Cep | 1975 |
Renal transport of organic acids and bases in aminoglycoside nephrotoxicity.
Topics: Acute Kidney Injury; Aminoglycosides; Animals; Biological Transport; Gentamicins; Kidney; Kidney Fun | 1979 |
Reversibility of gentamicin nephrotoxicity in rats: recovery during continuous drug administration.
Topics: Acute Kidney Injury; Animals; Creatinine; Gentamicins; Kidney Concentrating Ability; Kidney Tubular | 1979 |
Recurrent acute renal failure due to antibiotic-induced interstitial nephritis.
Topics: Acute Kidney Injury; Drug Combinations; Gentamicins; Humans; Male; Middle Aged; Nephritis, Interstit | 1979 |
Gentamycin toxicity--Fact or fiction?
Topics: Acute Kidney Injury; Gentamicins; Glomerular Filtration Rate; Humans | 1979 |
The influence of dosage regimen on experimental gentamicin nephrotoxicity: dissociation of peak serum levels from renal failure.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Drug Administ | 1979 |
[Legionnaires' disease: a new severe type of pneumonia].
Topics: Acute Kidney Injury; Cephalothin; Drug Therapy, Combination; Gentamicins; Humans; Legionnaires' Dise | 1979 |
[Cytosegregosomes in the kidney tubule cells in a case of acute renal insufficiency (ARI) caused by gentamycin].
Topics: Acute Kidney Injury; Epithelium; Gentamicins; Humans; Kidney Tubules; Laryngeal Neoplasms; Laryngect | 1979 |
[Sisomicin dosage in renal failure].
Topics: Acute Kidney Injury; Gentamicins; Humans; Kidney Failure, Chronic; Kinetics; Sisomicin | 1979 |
Malacoplakia of the kidney: apparent improvement following medical management.
Topics: Acute Kidney Injury; Adult; Female; Gentamicins; Humans; Malacoplakia; Peritoneal Dialysis | 1978 |
Renal tubular sodium and water excretion in antibiotic-induced nephrotoxicity. Renal function in antibiotic nephrotoxicity.
Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Body Water; Cephalothin; Colistin; Female; Gentam | 1978 |
[Acute posttraumatic renal failure following therapy with antibiotics and beta-aescin (author's transl)].
Topics: Acute Kidney Injury; Adult; Drug Interactions; Escin; Gentamicins; Humans; Male; Postoperative Compl | 1978 |
Acute renal failure after cis-dichlorodiammineplatinum(II) and gentamicin-cephalothin therapies.
Topics: Acute Kidney Injury; Adult; Aged; Cephalothin; Cisplatin; Drug Therapy, Combination; Female; Gentami | 1978 |
[Prediction of aminoglycoside nephrotoxicity (author's transl)].
Topics: Acute Kidney Injury; Aminoglycosides; Animals; Dogs; Gentamicins; Humans; Kidney; Kidney Cortex; Kid | 1978 |
[The problem of nephrotoxicity in the combination therapy with gentamycin and cephalothin].
Topics: Acute Kidney Injury; Cephalothin; Drug Synergism; Drug Therapy, Combination; Gentamicins; Humans | 1978 |
Gentamicin-associated acute renal failure.
Topics: Acute Kidney Injury; Aged; Dose-Response Relationship, Drug; Drug Therapy, Combination; Escherichia | 1976 |
Gentamicin nephrotoxicity--morphologic and pharmacologic features.
Topics: Acute Kidney Injury; Female; Gentamicins; Humans; Kidney; Kidney Glomerulus; Middle Aged | 1977 |
The effect of concomitant mercuric chloride and gentamicin on kidney function and structure in the rat.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Drug Interactions; Gentamicins; Glome | 1977 |
[Antibiotics and acute renal failure].
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Burns; Cephalothin; Colistin; Drug Therapy, Combin | 1977 |
[Nephrotoxicity of gentamicin. Conditions for the use of this antibiotic in the elderly and in the patient with renal insufficiency].
Topics: Acute Kidney Injury; Adult; Age Factors; Aged; Anti-Bacterial Agents; Drug Therapy, Combination; Fem | 1977 |
Ampicillin sodium and nephrotoxicity.
Topics: Acute Kidney Injury; Ampicillin; Gentamicins; Humans; Kidney; Nephritis, Interstitial | 1977 |
[The nephrotoxic potential of cefalotin-aminoside antibiotic combinations (author's transl)].
Topics: Acute Kidney Injury; Aminoglycosides; Animals; Cephalothin; Drug Synergism; Drug Therapy, Combinatio | 1977 |
Ultrastructural changes in gentamicin nephrotoxicity.
Topics: Acute Kidney Injury; Female; Gentamicins; Humans; Kidney; Kidney Tubules, Proximal; Middle Aged | 1977 |
Carbenicillin-gentamicin interaction in acute renal failure.
Topics: Acute Kidney Injury; Aged; Carbenicillin; Drug Interactions; Drug Therapy, Combination; Gentamicins; | 1977 |
[Nephrotoxicity of gentamycin-cephalothin combination therapy].
Topics: Acute Kidney Injury; Animals; Cephalothin; Drug Therapy, Combination; Gentamicins; Kidney Tubular Ne | 1977 |
[Nephortoxicity of a combination of cephalotin and gentamicin].
Topics: Acute Kidney Injury; Animals; Cephalothin; Drug Synergism; Drug Therapy, Combination; Female; Furose | 1976 |
Renal failure following gentamicin in combination with clindamycin.
Topics: Acute Kidney Injury; Aged; Clindamycin; Drug Synergism; Drug Therapy, Combination; Female; Gentamici | 1976 |
Renal glycosuria due to gentamicin in rabbits.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Gentamicins; Glomerular Filtration Rate; Glyco | 1976 |
Acute renal failure associated with cephalosporin therapy.
Topics: Acute Kidney Injury; Adult; Aged; Cephaloridine; Cephalothin; Drug Therapy, Combination; Endocarditi | 1975 |
Acute renal insufficiency complicating major cardiovascular surgery.
Topics: Abdomen; Abscess; Acute Kidney Injury; Adult; Age Factors; Aged; Bacteria; Blood Urea Nitrogen; Cand | 1975 |
Nephrotoxicity of combined cephalothin-gentamicin regimen.
Topics: Acute Kidney Injury; Aged; Blood Urea Nitrogen; Bronchopneumonia; Cephalothin; Drug Synergism; Drug | 1975 |
[Acute renal failure in the course of treatment with gentamicin alone or combined with other antibiotics. Report 6 cases].
Topics: Acute Kidney Injury; Adult; Aged; Cephalothin; Drug Therapy, Combination; Female; Gentamicins; Human | 1975 |
[Acute renal failure after intracranial injury in three children: analysis of possible causes (author's transl)].
Topics: Acute Kidney Injury; Age Factors; Brain Edema; Brain Injuries; Cephalothin; Child; Dextrans; Drug In | 1975 |
[The dangers of antibiotic therapy in gram-negative pathogens (author's transl)].
Topics: Acute Kidney Injury; Adult; Anuria; Bacterial Infections; Deafness; Drug Therapy, Combination; Femal | 1976 |
A light and electron microscopic analysis of gentamicin nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Gentamicins; Kidney Tubular Necrosis, | 1976 |
Reactive oxygen metabolites in toxic acute renal failure.
Topics: Acute Kidney Injury; Animals; Calcium; Cell Line; Free Radicals; Gentamicins; Glycerol; Humans; Hydr | 1992 |
[Mechanisms and therapeutic effect of Cordyceps sinensis (CS) on aminoglycoside induced acute renal failure (ARF) in rats].
Topics: Acute Kidney Injury; Animals; Drugs, Chinese Herbal; Gentamicins; Kanamycin; Kidney; Lysosomes; Male | 1992 |
[Endothelin and acute renal failure: study on their relation and possible mechanisms].
Topics: Acute Kidney Injury; Adult; Animals; Endothelins; Gentamicins; Hemorrhagic Fever with Renal Syndrome | 1992 |
Disposition of quinine in rats with induced renal failure.
Topics: Acute Kidney Injury; Animals; Chromatography, High Pressure Liquid; Gentamicins; Glycerol; Injection | 1992 |
Effects of desoxycorticosterone acetate (DOCA) plus saline drinking on gentamicin-mediated nephropathy in rats.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Desoxycorticosterone; Drug Evaluation, Preclinic | 1992 |
[Alterations in phosphatidylcholine and phospholipase A2 of the renal tissue in gentamicin nephrotoxicity: comparative study with buthionine sulfoximine administered model].
Topics: Acute Kidney Injury; Animals; Buthionine Sulfoximine; Disease Models, Animal; Gentamicins; Glutathio | 1992 |
Capnocytophaga canimorus infection and acute renal failure.
Topics: Acute Kidney Injury; Capnocytophaga; Gentamicins; Gram-Negative Bacterial Infections; Humans; Male; | 1992 |
Does gentamicin induce acute renal failure by increasing renal TXA2 synthesis in rats?
Topics: Acute Kidney Injury; Animals; Arginine Vasopressin; Catecholamines; Female; Gentamicins; Kidney; Met | 1992 |
Acute renal failure following hemorrhagic shock: protective and aggravating factors.
Topics: Acute Kidney Injury; Allopurinol; Animals; Calcium; Dehydration; Free Radicals; Gentamicins; Kidney; | 1992 |
Gentamicin clearance during continuous arteriovenous hemodiafiltration.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Drug Monitoring; Female; Forecasting; Gentamicins; Hem | 1992 |
Protective effect of zinc-induced metallothionein synthesis on gentamicin nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Free Radical Scavengers; Gentamicins; Hydroxides; Hydroxyl Radical; Ki | 1991 |
Gentamicin effects on renal ischemia/reperfusion injury.
Topics: Acute Kidney Injury; Acylation; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Female; Gent | 1992 |
Role of platelet activating factor in gentamicin and cisplatin nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Cisplatin; Diterpenes; Gentamicins; Ginkgolides; Glomerular Filtration | 1991 |
Gentamicin interval in newborn infants as determined by renal function and postconceptional age.
Topics: Acute Kidney Injury; Creatinine; Drug Administration Schedule; Gentamicins; Gestational Age; Glomeru | 1991 |
[Effects of the calcium-channel blocker diltiazem on gentamicin-induced nephrotoxicity in rats].
Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Diltiazem; Drug Interactions; Gentamicins; Male | 1991 |
Effects of dietary protein intake on muscle protein synthesis and degradation in rats with gentamicin-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Dietary Proteins; Gentamicins; Male; Muscle Proteins; Rats; Rats, Inbr | 1991 |
Iron supplementation increases gentamicin nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Body Weight; Diet; Gentamicins; Iron; Kidney Function Tests; Male; Nut | 1991 |
Enzymuria as an index of renal damage in sheep with induced aminoglycoside nephrotoxicosis.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Creatinine; Female; gamma-Glutamyltransferase; | 1990 |
The effect of oral activated charcoal on the systemic clearance of gentamicin in rabbits with acute renal failure.
Topics: Acute Kidney Injury; Animals; Charcoal; Gentamicins; Immunoenzyme Techniques; Male; Rabbits | 1990 |
Seasonal effects on the daily variations of gentamicin-induced nephrotoxicity.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Aminopeptidases; Animals; CD13 Antigens; Circadian Rhyth | 1990 |
Aminoaciduria is an earlier index of renal tubular damage than conventional renal disease markers in the gentamicin-rat model of acute renal failure.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Alanine; Amino Acids; Animals; Biomarkers; Creatinine; G | 1991 |
Mild ischemia predisposes the S3 segment to gentamicin toxicity.
Topics: Acute Kidney Injury; Animals; Gentamicins; Ischemia; Kidney; Kidney Function Tests; Kidney Tubules, | 1990 |
Renal dysfunction associated with ciprofloxacin.
Topics: Acute Kidney Injury; Ciprofloxacin; Creatinine; Female; Gentamicins; Humans; Kidney Concentrating Ab | 1990 |
Do the H2-receptor antagonists, cimetidine and famotidine, modify the degree of renal recovery following renal insult?
Topics: Acute Kidney Injury; Animals; Cimetidine; Constriction; Famotidine; Gentamicins; Kidney; Male; Rats; | 1990 |
Lack of effect of glutathione depletion by L-buthionine-S,R-sulfoximine on gentamicin nephrotoxicity in rats.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Antimetabolites; Buthionine Sulfoximine; Creati | 1990 |
Urinary indices of renal function in sheep with induced aminoglycoside nephrotoxicosis.
Topics: Acute Kidney Injury; Animals; Blood Glucose; Electrolytes; Female; Gentamicins; Glycosuria; Hyperpla | 1990 |
[Nephrotoxicity of the combination of cyclosporin and aminoglycoside in rats. Comparative study of gentamicin and amikacin].
Topics: Acetylglucosaminidase; Acute Kidney Injury; Amikacin; Animals; Cyclosporins; Drug Therapy, Combinati | 1990 |
Procainamide toxicity in a patient with acute renal failure.
Topics: Acecainide; Acute Kidney Injury; Administration, Oral; Aged; Arrhythmias, Cardiac; Gentamicins; Hemo | 1986 |
Role of the prostaglandin and kallikrein-kinin systems in aminoglycoside-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Aprotinin; Cyclooxygenase Inhibitors; Gentamicins; Glomerular Filtrati | 1985 |
Amylase-creatinine clearance ratio. A simple test to predict gentamicin nephrotoxicity.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Amylases; Creatinine; Female; Gentamicins; Glomerular | 1988 |
Gentamicin-induced glomerulotoxicity in the pregnant rat.
Topics: Acute Kidney Injury; Animals; Enalapril; Female; Gentamicins; Glomerular Filtration Rate; Hematocrit | 1989 |
Protective effect of thyroxine but not parathyroidectomy on gentamicin nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Body Weight; Calcium; Extracellular Space; Gentamicins; Glomerular Fil | 1985 |
The effect of oral calcium load or verapamil on gentamicin-induced nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Calcium, Dietary; Creatinine; Drug Interactions; Gentamicins; Glomerul | 1989 |
Model of gentamicin-induced nephrotoxicity and its amelioration by calcium and thyroxine.
Topics: Acute Kidney Injury; Calcium; Gentamicins; Humans; Thyroxine | 1989 |
Phlorizin-induced glycosuria does not prevent gentamicin nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Diabetes Mellitus, Experimental; Female; Gentamicins; Glycosuria; Kidn | 1989 |
Diltiazem enhances gentamicin nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Diltiazem; Drug Synergism; Gentamicins; Kidney Tubular Necrosis, Acute | 1989 |
[Acute renal insufficiency after the administration of tetracycline and gentamycin].
Topics: Acute Kidney Injury; Aged; Female; Gentamicins; Humans; Male; Middle Aged; Tetracycline | 1989 |
[Renal dipeptidylpeptidase IV excretion in drug-induced kidney changes].
Topics: Acute Kidney Injury; Adolescent; Adult; Aminopeptidases; CD13 Antigens; Cephalothin; Chemotherapy, C | 1986 |
In defence of gentamicin.
Topics: Acute Kidney Injury; Animals; Female; gamma-Glutamyltransferase; Gentamicins; Horse Diseases; Horses | 1987 |
Effect of alkylxanthines on gentamicin-induced acute renal failure in the rat.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Creatinine; Gentamicins; Kidney; Male; Organ Si | 1988 |
Aminoglycoside pharmacokinetics: dosage requirements and nephrotoxicity in trauma patients.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Craniocerebral Trauma; Creatinine; | 1989 |
Effect of magnesium diet in gentamicin-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Creatinine; Diet; Electrolytes; Gentamicins; Kidney; Magnesium; Male; | 1989 |
Atrial natriuretic peptide in gentamicin-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Atrial Natriuretic Factor; Diuresis; Electrolytes; Female; Gentamicins | 1988 |
Gentamicin and gram-negative bacteremia. A synergism for the development of experimental nephrotoxic acute renal failure.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Drug Synergism; Endotoxins; Escherichia coli; Female; | 1986 |
Evidence suggesting a role for hydroxyl radical in gentamicin-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Benzoates; Benzoic Acid; Chelating Agents; Deferoxamine; Dimethyl Sulf | 1988 |
The protective effect of nitrendipine on gentamicin acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Hemodynamics; Kidney; Kidney Diseases; Kidney Fun | 1985 |
[Acute renal insufficiency secondary to gentamicin].
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Female; Gentamicins; Humans; Kidney; Male; Middle Aged | 1988 |
Potassium excretion in renal failure in the rat: the role of distal tubule flow and aldosterone.
Topics: Acute Kidney Injury; Adrenalectomy; Aldosterone; Animals; Creatinine; Diet; Female; Gentamicins; Glo | 1988 |
A focus of tissue necrosis increases renal susceptibility to gentamicin administration.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Female; Gentamicins; Kidney; Necrosis | 1988 |
Gentamicin-induced nephrotoxicosis in a cow.
Topics: Acute Kidney Injury; Animals; Cattle; Cattle Diseases; Female; Gentamicins; Kidney Tubules; Microsco | 1988 |
Kinetics of gentamicin elimination in two horses with acute renal failure.
Topics: Acute Kidney Injury; Animals; Creatinine; Female; Gentamicins; Horse Diseases; Horses; Male | 1988 |
Electrolyte composition of renal tubular cells in gentamicin nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Electrolytes; Electron Probe Microanalysis; Freeze Drying; Gentamicins | 1988 |
[Gentamicin dosage in critical patients with acute renal insufficiency. Evaluation of a formula based on plasma creatinine levels].
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Creatinine; Female; Gentamicins; Glomerular Fil | 1987 |
[An early and specific indicator of aminoglycoside nephrotoxicity: isoenzyme B of urinary N-acetyl-beta-D-glucosaminidase (NAG)].
Topics: Acetylglucosaminidase; Acute Kidney Injury; Aged; Amikacin; Aminoglycosides; Anti-Bacterial Agents; | 1986 |
Gentamicin-induced loss of basolateral surface area of rat proximal convoluted tubules.
Topics: Acute Kidney Injury; Animals; Creatinine; Disease Models, Animal; Gentamicins; Kidney Tubules, Proxi | 1987 |
Proton MR study of different types of experimental acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Glycerol; Kidney; Magnetic Resonance Imaging; Mal | 1986 |
Antibiotic-induced acute renal failure associated with an elevated serum lactic dehydrogenase level of renal origin.
Topics: Acute Kidney Injury; Cefazolin; Gentamicins; Humans; Kidney; L-Lactate Dehydrogenase; Male; Middle A | 1986 |
[Isoenzymes of N-acetyl-beta-D-glucosaminidase (NAG): new method of evaluating the nephrotoxicity of aminosides. Our experience with dibekacin in geriatrics].
Topics: Acetylglucosaminidase; Acute Kidney Injury; Aged; Dibekacin; Female; Gentamicins; Hexosaminidases; H | 1986 |
Chronic gentamicin nephrotoxicity. Continued tubular injury with preserved glomerular filtration function.
Topics: Acute Kidney Injury; Autoradiography; Drug Resistance; Gentamicins; Glomerular Filtration Rate; Hist | 1986 |
Gentamicin-associated acute renal failure in the dog.
Topics: Acute Kidney Injury; Animals; Dog Diseases; Dogs; Female; Gentamicins; Male; Prognosis | 1985 |
[Intracellular calcium and renal function].
Topics: Acute Kidney Injury; Animals; Biological Transport, Active; Calcium; Calcium Channel Blockers; Calmo | 1985 |
Gentamicin and renal failure.
Topics: Acute Kidney Injury; Aged; Gentamicins; Humans; Male | 1972 |
Tetracycline, methoxyflurane anaesthesia, and renal dysfunction.
Topics: Acute Kidney Injury; Drug Synergism; Gentamicins; Humans; Kanamycin; Kidney; Methoxyflurane; Tetracy | 1972 |
Acute renal failure after high doses of gentamicin and cephalothin.
Topics: Acute Kidney Injury; Adult; Aged; Cephalothin; Female; Gentamicins; Humans; Male; Middle Aged; Perit | 1973 |
Acute renal failure after high doses of gentamicin and cephalothin.
Topics: Acute Kidney Injury; Bacterial Infections; Cephalothin; Gentamicins; Humans | 1973 |
Experience in monitoring gentamicin therapy during treatment of serious gram-negative sepsis.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Bacteria; Bacteriuria; Cephalosporins; Escherichia col | 1974 |
Nephrotoxicity of anti-infective drugs.
Topics: Acute Kidney Injury; Amphotericin B; Anti-Bacterial Agents; Bacitracin; Cephaloridine; Colistin; Dru | 1968 |
Complications of antimicrobial therapy.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cephalosporins; Chloramphenicol; Drug Hypersensitivity; | 1973 |
[Tubulointerstitial nephropathies due to antibiotics].
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cephalexin; Cephaloridine; Cephalothin; Drug Hypersensit | 1973 |
[Antibiotics in renal insufficiency (author's transl)].
Topics: Acute Kidney Injury; Ampicillin; Anti-Bacterial Agents; Carbenicillin; Cephaloridine; Cephalothin; C | 1974 |
[Acute renal failure caused by the combination of cephalothin and gentamicin].
Topics: Acute Kidney Injury; Cephalothin; Drug Therapy, Combination; Gentamicins; Humans; Leg Ulcer; Male; M | 1974 |
Acute renal failure after abdominal surgery. The importance of sepsis.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Child; Colistin; Drainage; Female; Gentamicins; Humans | 1974 |
[Acute renal failure with prolonged oligo-anuria caused by gentamicin].
Topics: Acute Kidney Injury; Aged; Biopsy; Cholelithiasis; Gentamicins; Humans; Kidney Tubules; Male; Surgic | 1974 |
[Renal damage during combined therapy with gentamicin and cephalothin].
Topics: Acute Kidney Injury; Aged; Cephalothin; Drug Therapy, Combination; Female; Gentamicins; Humans; Kidn | 1974 |
[Nephrotoxicity of cephalotin-gentamycin association. Clinical study of 4 cases].
Topics: Acute Kidney Injury; Aged; Anuria; Cephalothin; Cholecystitis; Drug Combinations; Endocarditis, Bact | 1974 |
Infections in renal failure.
Topics: Acute Kidney Injury; Ampicillin; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cephalothin; | 1973 |
Reflections on the clinical pharmacology of gentamicin.
Topics: Acute Kidney Injury; Dose-Response Relationship, Drug; Female; Gentamicins; Humans; Injections, Intr | 1973 |
[Acute renal failure following combined cephaloridine-gentamycin therapy (author's transl)].
Topics: Acute Kidney Injury; Cephaloridine; Drug Synergism; Escherichia coli Infections; Female; Gentamicins | 1973 |
Anuria and acute tubular necrosis associated with gentamicin and cephalothin.
Topics: Acute Kidney Injury; Adult; Anuria; Autopsy; Cephalothin; Gentamicins; Humans; Lymphoma; Lymphoma, N | 1972 |
[Acute renal failure during treatment with gentamicin and cephalothin].
Topics: Acute Kidney Injury; Aged; Cephalothin; Diuresis; Drug Interactions; Gentamicins; Half-Life; Humans; | 1973 |
[Acute renal failure after administration of cephalothin and gentamycin].
Topics: Acute Kidney Injury; Adult; Biopsy; Cephalothin; Colitis; Crohn Disease; Diarrhea; Endocarditis, Bac | 1973 |
Acute renal failure associated with combined gentamicin and cephalothin therapy.
Topics: Acute Kidney Injury; Adult; Cephalothin; Creatinine; Drug Interactions; Female; Furosemide; Gentamic | 1973 |
Renal failure in combined gentamicin and cephalothin therapy.
Topics: Acute Kidney Injury; Aged; Cephalothin; Gentamicins; Humans; Injections, Intramuscular; Kidney; Male | 1973 |
Antibiotic-induced meningitis.
Topics: Acute Kidney Injury; Aged; Cephalothin; Drug Synergism; Female; Gentamicins; Humans; Kanamycin; Male | 1973 |
[Gentamicin and peritoneal dialysis].
Topics: Acute Kidney Injury; Gentamicins; Humans; Kidney Failure, Chronic; Peritoneal Dialysis | 1973 |
[Gentamicin and hemodialysis].
Topics: Acute Kidney Injury; Gentamicins; Humans; Kidney Failure, Chronic; Renal Dialysis | 1973 |
Endotracheal administration of gentamicin. Relationship between obtained serum levels and creatininemia.
Topics: Acute Kidney Injury; Biological Assay; Creatinine; Dose-Response Relationship, Drug; Gentamicins; Hu | 1973 |
Nephrotoxicity of gentamicin.
Topics: Acid Phosphatase; Acute Kidney Injury; Animals; Anuria; Blood Urea Nitrogen; Body Weight; Dose-Respo | 1974 |
[Use of gentamycin in renal failure (our experience in 31 patients)].
Topics: Acute Kidney Injury; Adult; Aged; Bacterial Infections; Drug Evaluation; Female; Gentamicins; Humans | 1974 |
[Kidney insufficiency after treatment with the antibiotic drug combination cephalothin-gentamicin].
Topics: Acute Kidney Injury; Administration, Oral; Aged; Cephalothin; Creatinine; Drug Synergism; Drug Thera | 1974 |
[The difficulties of drug management in renal insufficiency (author's transl)].
Topics: Acute Kidney Injury; Gentamicins; Humans; Kidney Failure, Chronic; Tetracycline | 1974 |
[Letter: Renal tolerance of gentamycin].
Topics: Acute Kidney Injury; Drug Tolerance; Gentamicins; Humans; Kidney | 1974 |
[Comparative study of the nephrotoxicity of gentamicin with constant and intermittent administration of the antibiotic].
Topics: Acute Kidney Injury; Adult; Aged; Drug Evaluation; Female; Gentamicins; Humans; Injections, Intramus | 1974 |
[Current problems in burns].
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Burns; Drug Resistance, Microbial; Gentamicins; Hospital | 1968 |
Peritoneal clearance and removal of gentamicin.
Topics: Acute Kidney Injury; Aged; Enterobacteriaceae Infections; Female; Gentamicins; Humans; Kidney Failur | 1971 |
The use of gentamicin in peritoneal dialysis. II. Microbiologic and clinical results.
Topics: Acute Kidney Injury; Alcaligenes; Candidiasis; Carbenicillin; Cephalothin; Drug Synergism; Escherich | 1971 |
[Epidemiology of Pseudomonas aeruginosa infections in a unit for the treatment of renal failure].
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Air Microbiology; Ampicillin; Ascitic Fluid; Bacterioc | 1969 |
Gentamicin dosages for renal insufficiency. Adjustments based on endogenous creatinine clearance and serum creatinine concentration.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Blood Urea Nitrogen; Creatinine; Drug Resistance, Micr | 1971 |
Relation between dose and levels of gentamicin in blood.
Topics: Acute Kidney Injury; Agar; Biological Assay; Clinical Laboratory Techniques; Creatinine; Gentamicins | 1971 |
Suspected neurotoxicity from intravenous penicillin: a patient case.
Topics: Acute Kidney Injury; Ampicillin; Blood Urea Nitrogen; Chronic Disease; Creatine; Diazepam; Gentamici | 1972 |
[Acute renal failure following gentamicin-cephalosporin association therapy].
Topics: Acute Kidney Injury; Adult; Aged; Cephaloridine; Cephalosporins; Cephalothin; Female; Gentamicins; H | 1971 |
Renal insufficiency associated with gentamicin therapy.
Topics: Acute Kidney Injury; Adult; Aged; Blood Urea Nitrogen; Creatinine; Female; Gentamicins; Humans; Kidn | 1971 |
Possible nephrotoxicity of gentamicin.
Topics: Acute Kidney Injury; Adult; Age Factors; Aminohippuric Acids; Animals; Creatinine; Dehydration; Dise | 1971 |
The use of gentamicin in peritoneal dialysis. I. Pharmacologic results.
Topics: Acute Kidney Injury; Drug Resistance, Microbial; Gentamicins; Half-Life; Humans; Injections, Intramu | 1971 |
[Acute deafness after gentamycin treatment of anuria].
Topics: Acute Disease; Acute Kidney Injury; Adult; Anuria; Deafness; Ear, Inner; Electrophysiology; Gentamic | 1969 |
Opportunistic infection.
Topics: Acute Kidney Injury; Adult; Alcaligenes; Aspergillosis; Autopsy; Brain; Brain Diseases; Candidiasis; | 1970 |
More on antimicrobials in renal failure.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Chloramphenicol; Colistin; Gentamicins; Humans; Nitrofur | 1968 |