gentamicin has been researched along with Acoustic Trauma in 16 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Acoustic Trauma: Usually refer to hearing loss due to a single noise event such as an explosion or shotgun blast.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In contrast, intratympanic gentamicin injection inducing permanent cell damage and mean hearing loss of 24dB correlated with a significant Birc5 downregulation in the ligament, nerve fibers and the organ of Corti." | 3.76 | Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear. ( Bier, C; Brieger, J; Brochhausen, C; Docter, D; Habtemichael, N; Heinrich, UR; Helling, K; Knauer, SK; Mann, WJ; Schmidtmann, I; Stauber, RH, 2010) |
| "The role of mitochondrial biogenesis in hair cell survival after injury was evaluated by inhibiting mitochondrial protein synthesis with chloramphenicol and then studying the effects on hair cell survival after exposure to two different types of ototoxins, gentamicin and acoustic trauma." | 3.69 | Mitochondrial role in hair cell survival after injury. ( Hyde, GE; Rubel, EW, 1995) |
| "Experimental sensorineural hearing loss was created in six monkeys by ototoxic drug administration (gentamicin) and in three monkeys by exposure to intense sound." | 1.26 | Impedance audiometry in the squirrel monkey. Sensorineural losses. ( Igarashi, M; Jerger, J; Mauldin, L, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 8 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strose, A | 1 |
| Colombari, GC | 1 |
| Rossato, M | 1 |
| Hyppolito, MÂ | 1 |
| de Oliveira, JA | 1 |
| Habtemichael, N | 1 |
| Heinrich, UR | 1 |
| Knauer, SK | 1 |
| Schmidtmann, I | 1 |
| Bier, C | 1 |
| Docter, D | 1 |
| Brochhausen, C | 1 |
| Helling, K | 1 |
| Brieger, J | 1 |
| Stauber, RH | 1 |
| Mann, WJ | 1 |
| Polesskaya, O | 1 |
| Cunningham, LL | 1 |
| Francis, SP | 1 |
| Luebke, AE | 1 |
| Zhu, X | 1 |
| Collins, D | 1 |
| Vasilyeva, ON | 1 |
| Sahler, J | 1 |
| Desmet, EA | 1 |
| Gelbard, HA | 1 |
| Maggirwar, SB | 1 |
| Walton, JP | 1 |
| Frisina, RD | 1 |
| Dewhurst, S | 1 |
| Li, H | 1 |
| Wang, Q | 1 |
| Steyger, PS | 1 |
| Hyde, GE | 1 |
| Rubel, EW | 1 |
| Henley, CM | 1 |
| Rybak, LP | 1 |
| Cotanche, DA | 2 |
| Lee, KH | 1 |
| Stone, JS | 1 |
| Picard, DA | 1 |
| Alles, RM | 1 |
| Pye, A | 1 |
| Vormann, J | 1 |
| Günther, T | 1 |
| Adler, HJ | 1 |
| Komeda, M | 1 |
| Raphael, Y | 1 |
| Ofsie, MS | 1 |
| Hennig, AK | 1 |
| Messana, EP | 1 |
| Sliwińska-Kowalska, M | 1 |
| Kotylo, P | 1 |
| Jerger, J | 1 |
| Mauldin, L | 1 |
| Igarashi, M | 1 |
| Hawkins, JE | 2 |
| Johnsson, LG | 2 |
| Preston, RE | 1 |
4 reviews available for gentamicin and Acoustic Trauma
| Article | Year |
|---|---|
Ototoxicity in developing mammals.
Topics: Age Distribution; Age Factors; Animals; Animals, Newborn; Cochlea; Deafness; Diuretics; Ear, Inner; | 1995 |
Hair cell regeneration in the bird cochlea following noise damage or ototoxic drug damage.
Topics: Animals; Gentamicins; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Kanamycin; Microscopy, Elec | 1994 |
Influence of magnesium on drug- and noise-induced inner ear damage. Animal studies.
Topics: Animals; Animals, Newborn; Female; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Hearing Loss, Noi | 1993 |
Committee on Environmental Hazards. Noise pollution: neonatal aspects.
Topics: Adrenocorticotropic Hormone; Animals; Cats; Deafness; Environmental Exposure; Gentamicins; Guinea Pi | 1974 |
1 trial available for gentamicin and Acoustic Trauma
| Article | Year |
|---|---|
[Is otoacoustic emission useful in the differential diagnosis of occupational noise-induced hearing loss?].
Topics: Acoustic Impedance Tests; Adult; Audiometry, Pure-Tone; Cochlea; Diagnosis, Differential; Environmen | 1997 |
11 other studies available for gentamicin and Acoustic Trauma
| Article | Year |
|---|---|
Gentamicin conditioning confers auditory protection against noise trauma.
Topics: Acoustic Stimulation; Animals; Anti-Bacterial Agents; Auditory Threshold; Cochlea; Disease Models, A | 2014 |
Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear.
Topics: Animals; Cells, Cultured; Cytoprotection; Ear, Inner; Female; Gentamicins; Guinea Pigs; Hearing Loss | 2010 |
Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure.
Topics: Animals; Cell Death; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Female; Gentam | 2010 |
Acoustic trauma increases cochlear and hair cell uptake of gentamicin.
Topics: Animals; Anti-Bacterial Agents; Biological Transport; Gentamicins; Hair Cells, Auditory; Hearing Los | 2011 |
Mitochondrial role in hair cell survival after injury.
Topics: Animals; Animals, Newborn; Awards and Prizes; Cell Survival; Chickens; Chloramphenicol; Gentamicins; | 1995 |
Cochlear damage in guinea pigs following contralateral sound stimulation with and without gentamicin.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Cochlear Diseases; Ear Protective Devices; Gent | 1993 |
Further evidence for supporting cell conversion in the damaged avian basilar papilla.
Topics: Animals; Anti-Bacterial Agents; Antimetabolites; Bromodeoxyuridine; Cell Differentiation; Chickens; | 1997 |
Sound damage and gentamicin treatment produce different patterns of damage to the efferent innervation of the chick cochlea.
Topics: Animals; Anti-Bacterial Agents; Basilar Membrane; Chickens; Choline O-Acetyltransferase; Cochlea; Ef | 1997 |
Impedance audiometry in the squirrel monkey. Sensorineural losses.
Topics: Acoustic Impedance Tests; Acoustic Stimulation; Animals; Gentamicins; Haplorhini; Hearing Loss, Nois | 1978 |
Cochlear microvasculature in normal and damaged ears.
Topics: Capillaries; Cochlea; Ear; Gentamicins; Hearing Loss, Noise-Induced; Humans; Labyrinth Diseases; Mic | 1972 |
Strial atrophy in clinical and experimental deafness.
Topics: Animals; Atrophy; Basement Membrane; Blood Vessels; Cochlea; Deafness; Dogs; Ethacrynic Acid; Gentam | 1972 |