gentamicin has been researched along with Abnormalities, Drug-Induced in 22 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, taking advantage of the transparency of larval zebrafish, Danio rerio, we assessed cardiovascular toxicity of seven known human cardiotoxic drugs (aspirin, clomipramine hydrochloride, cyclophosphamide, nimodipine, quinidine, terfenadine and verapamil hydrochloride) and two non-cardiovascular toxicity drugs (gentamicin sulphate and tetracycline hydrochloride) in zebrafish using six specific phenotypic endpoints: heart rate, heart rhythm, pericardial edema, circulation, hemorrhage and thrombosis." | 3.80 | Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish. ( Dong, QX; Gao, JM; He, JH; Huang, CJ; Li, CQ; Xu, YQ; Xuan, YX; Yu, HP; Zhu, JJ, 2014) |
| "The aim of this study was to investigate the teratogenicity of aminoglycoside antibiotics, such as parenteral gentamicin, streptomycin, tobramycin and oral neomycin, during pregnancy." | 3.70 | A teratological study of aminoglycoside antibiotic treatment during pregnancy. ( Czeizel, AE; Olsen, J; Rockenbauer, M; Sørensen, HT, 2000) |
| " Netilmicin is less toxic to the VIIIth nerve than is gentamicin in all species tested." | 2.36 | Netilmicin: a review of toxicity in laboratory animals. ( Luft, FC, 1978) |
| "Gentamicin was still present in urine 3 mo after birth." | 1.28 | Long-term effects of mild oligonephronia induced in utero by gentamicin in the rat. ( Gilbert, T; Lelievre-Pegorier, M; Merlet-Benichou, C, 1991) |
| " There was no adverse effect on fertility ability at any dose." | 1.27 | [Safety evaluation of micronomicin VII. Fertility study by intravenous injection in rats]. ( Deguchi, T; Fujita, T; Hara, T; Takahashi, H, 1983) |
| " There was no adverse effect on new borns at any dose." | 1.27 | [Safety evaluation of micronomicin VIII. Teratogenicity studies in rabbits after intravenous injection]. ( Deguchi, T; Fujita, T; Hara, T; Takahashi, H, 1983) |
| " There was no adverse effect on new borns at any dose." | 1.27 | [Safety evaluation of micronomicin. III. Teratogenicity studies in rats]. ( Hara, T; Miyazaki, H; Nishikawa, S; Ohguro, Y, 1983) |
| " Dose-response effects of HAPA-B on offspring were not observed in the postnatal study." | 1.27 | [Effect of isepamicin (HAPA-B) on reproduction. II. Teratological study in rats (intramuscular administration)]. ( Kawaguchi, K; Kobayashi, Y; Sasaki, M; Yamada, H; Yamamoto, H, 1986) |
| "Gentamicin-treated mothers presented only minor modifications of the blood biology with no acute renal failure when treated nonpregnant females have a hypercreatininemia." | 1.27 | In-utero gentamicin-induced nephrotoxicity in rats. ( Gerard, A; Gerard, H; Mallié, JP, 1986) |
| " The decrease of food intake at the dosage of 50 mg/kg and more, and the resultant depression of maternal body weight gain at the dosage of 100 mg/kg were observed in dams receiving NTL." | 1.26 | [Reproduction study on netilmicin. (1) Teratological study in rats (author's transl)]. ( Furuhashi, T; Komuro, E; Miyoshi, K; Nakayoshi, H; Nomura, A; Uehara, M, 1982) |
| "The 13th gestational day inner ear (otocyst stage) is particularly vulnerable to toxic influence from the environment during its further development." | 1.26 | Ototoxicity or teratogenicity. An analysis of drug-induced effects on the early development of the mammalian otocyst. ( Anniko, M; Nordemar, H, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (72.73) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deschênes, G | 1 |
| Zhu, JJ | 1 |
| Xu, YQ | 1 |
| He, JH | 1 |
| Yu, HP | 1 |
| Huang, CJ | 1 |
| Gao, JM | 1 |
| Dong, QX | 1 |
| Xuan, YX | 1 |
| Li, CQ | 1 |
| Yaris, F | 1 |
| Kesim, M | 1 |
| Kadioglu, M | 1 |
| Kul, S | 1 |
| Hara, T | 3 |
| Fujita, T | 2 |
| Takahashi, H | 2 |
| Deguchi, T | 2 |
| Nishikawa, S | 1 |
| Miyazaki, H | 1 |
| Ohguro, Y | 1 |
| Zenk, KE | 1 |
| Nomura, A | 4 |
| Furuhashi, T | 4 |
| Komuro, E | 1 |
| Uehara, M | 2 |
| Miyoshi, K | 2 |
| Nakayoshi, H | 4 |
| Tsujibayashi, K | 1 |
| Nichoga, LA | 1 |
| Skosyreva, AM | 1 |
| Voropaeva, SD | 1 |
| Weinberg, EH | 1 |
| Field, WE | 1 |
| Gray, WD | 1 |
| Klein, MF | 1 |
| Robbins, GR | 1 |
| Schwartz, E | 1 |
| Anniko, M | 1 |
| Nordemar, H | 1 |
| Czeizel, AE | 1 |
| Rockenbauer, M | 1 |
| Olsen, J | 1 |
| Sørensen, HT | 1 |
| Luft, FC | 1 |
| Gilbert, T | 1 |
| Lelievre-Pegorier, M | 1 |
| Merlet-Benichou, C | 1 |
| Smaoui, H | 1 |
| Mallie, JP | 2 |
| Cheignon, M | 1 |
| Borot, C | 1 |
| Schaeverbeke, J | 1 |
| Sasaki, M | 1 |
| Kawaguchi, K | 1 |
| Yamada, H | 1 |
| Kobayashi, Y | 1 |
| Yamamoto, H | 1 |
| Gerard, H | 1 |
| Gerard, A | 1 |
| Welles, JS | 1 |
| Emmerson, JL | 1 |
| Gibson, WR | 1 |
| Nickander, R | 1 |
| Owen, NV | 1 |
| Anderson, RC | 1 |
| Beretić, T | 1 |
3 reviews available for gentamicin and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[Renal toxicity of drugs in the neonate].
Topics: Abnormalities, Drug-Induced; Anti-HIV Agents; Bartter Syndrome; Fanconi Syndrome; Female; Gentamicin | 2010 |
An overview of perinatal clinical pharmacology.
Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digo | 1981 |
Netilmicin: a review of toxicity in laboratory animals.
Topics: Abnormalities, Drug-Induced; Amikacin; Animals; Anti-Bacterial Agents; Bacterial Infections; Cochlea | 1978 |
19 other studies available for gentamicin and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cardiotoxins; Clomipramine; Cyclophosphamide; Disease | 2014 |
Gentamicin use in pregnancy. A renal anomaly.
Topics: Abnormalities, Drug-Induced; Adult; Anti-Infective Agents; Ciprofloxacin; Drug Therapy, Combination; | 2004 |
[Safety evaluation of micronomicin VII. Fertility study by intravenous injection in rats].
Topics: Abnormalities, Drug-Induced; Aminoglycosides; Animals; Anti-Bacterial Agents; Body Weight; Female; F | 1983 |
[Safety evaluation of micronomicin VIII. Teratogenicity studies in rabbits after intravenous injection].
Topics: Abnormalities, Drug-Induced; Aminoglycosides; Animals; Anti-Bacterial Agents; Body Weight; Female; F | 1983 |
[Safety evaluation of micronomicin. III. Teratogenicity studies in rats].
Topics: Abnormalities, Drug-Induced; Aminoglycosides; Animals; Anti-Bacterial Agents; Body Weight; Drug Eval | 1983 |
[Reproduction study on netilmicin. (1) Teratological study in rats (author's transl)].
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Drinking; Eat | 1982 |
[Reproduction study on netilmicin. (2) Fertility study in rats (author's transl)].
Topics: Abnormalities, Drug-Induced; Animals; Drinking; Eating; Female; Fertility; Fetus; Gentamicins; Injec | 1982 |
[Reproduction study on netilmicin. (3) Perinatal and postnatal study in rats (author's transl)].
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Body Weight; Female; Fertility; Fetus; Genta | 1982 |
[Reproduction study on netilmicin. (4) Teratological study in rabbits (author's transl)].
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Drinking; Eating; Female; Fetus; Gentamicins; | 1982 |
[Transplacental passage of gentamicin and its effect on the fetus].
Topics: Abnormalities, Drug-Induced; Animals; Endometritis; Female; Fetus; Gentamicins; Humans; Maternal-Fet | 1982 |
Preclinical toxicologic studies of netilmicin.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Dogs; Dose-Response Relationship, Drug; Fema | 1981 |
Ototoxicity or teratogenicity. An analysis of drug-induced effects on the early development of the mammalian otocyst.
Topics: Abnormalities, Drug-Induced; Animals; Ear, Inner; Female; Gentamicins; Mice; Mice, Inbred CBA; Micro | 1981 |
A teratological study of aminoglycoside antibiotic treatment during pregnancy.
Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Case-Control Studies; Female; Gentamicins; Human | 2000 |
Long-term effects of mild oligonephronia induced in utero by gentamicin in the rat.
Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Female; Gentamicins; Glomerular Filtration Rate; | 1991 |
Glomerular alterations in rat neonates after transplacental exposure to gentamicin.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Basement Membrane; Female; Gentamicins; Kidn | 1991 |
[Effect of isepamicin (HAPA-B) on reproduction. II. Teratological study in rats (intramuscular administration)].
Topics: Abnormalities, Drug-Induced; Animals; Female; Fertility; Fetus; Gentamicins; Injections, Intramuscul | 1986 |
In-utero gentamicin-induced nephrotoxicity in rats.
Topics: Abnormalities, Drug-Induced; Animals; Blood Chemical Analysis; Female; Gentamicins; Kidney; Maternal | 1986 |
Preclinical toxicology studies with tobramycin.
Topics: Abnormalities, Drug-Induced; Alanine Transaminase; Amino Sugars; Animals; Anti-Bacterial Agents; Blo | 1973 |
[Teratogenesis and drug control].
Topics: Abnormalities, Drug-Induced; Aminosalicylic Acids; Androgens; Animals; Chlordiazepoxide; Drug and Na | 1967 |