Page last updated: 2024-09-02

geniposide and Innate Inflammatory Response

geniposide has been researched along with Innate Inflammatory Response in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (4.17)29.6817
2010's10 (41.67)24.3611
2020's13 (54.17)2.80

Authors

AuthorsStudies
Chen, JS; Chen, YY; Guo, X; Liu, C; Liu, YF; Sun, JY; Wang, MM; Wang, MX; Zhang, MQ; Zhang, YK1
Du, S; Guo, Y; Li, L; Tu, Y; Wang, Z; Zhang, Y; Zhu, L; Zhu, M1
Chen, JS; Guo, X; Liao, ZX; Liu, C; Liu, JS; Sun, JY; Wang, MM; Wang, MX; Zhang, J; Zhang, MQ1
Bian, Y; Dou, DH; Gu, Y; Shi, JX; Shi, L; Yu, B; Yu, Y; Yuan, DP1
Ji, T; Jin, X; Li, R; Quan, Z; Tong, H; Xu, F; Xue, L; Yu, W; Zhuge, X1
Hong, W; Ran, D; Yan, W; Yanhong, B1
Dong, L; Gao, X; Lan, M; Li, C; Luo, G; Lv, J; Sun, J; Zhang, H; Zhang, Y1
Cheng, J; Feng, H; Jin, M; Li, Z; Liu, G; Qin, H; Shen, B; Wang, Q; Zhao, L1
Cui, J; Gao, Y; Huang, L; Qi, L; Sun, Y; Zhao, K; Zhou, S1
Liu, J; Shi, G; Wang, H; Zhao, N1
Li, C; Liu, Y; Pu, Z; Xie, H; Xu, M; Zhao, J1
Hong, W; Mengdie, W; Ran, D; Yan, W1
Chen, J; Chen, Y; Huang, M; Li, F; Li, Y; Song, L; Zhao, W1
Li, H; Li, M; Liu, J; Shi, Y; Wang, B; Wang, Y; Yang, H1
Cao, Y; Fu, Y; Li, S; Li, Y; Liu, B; Liu, J; Lu, X; Shen, P; Zhang, N; Zhang, Z1
Chen, H; Chen, R; Lin, Z; Pan, J; Pan, T; Shi, X; Wu, D; Zhang, J1
Sheng, C; Su, Q; Yao, J1
Bao, T; Chen, Y; Gong, C; Shou, K; Yang, H; Yang, Y1
Kong, CY; Ma, ZG; Song, P; Tang, QZ; Yuan, YP; Zhang, X1
Dai, Y; Gu, R; Jiang, R; Ma, S; Zhang, C; Zhang, Z1
Huang, C; Li, J; Li, WX; Li, XF; Ma, TT; Meng, XM; Yang, Y; Zhang, L1
Guo, X; Huang, G; Kang, S; Li, F; Li, W; Li, X; Liu, Y; Ma, J; Wan, L; Wang, B; Zhang, L; Zhang, S1
Hou, J; Li, D; Liu, J; Wang, J; Zhang, C; Zhang, P1
Jung, HJ; Koo, HJ; Lim, KH; Park, EH1

Reviews

1 review(s) available for geniposide and Innate Inflammatory Response

ArticleYear
Properties and molecular mechanisms underlying geniposide-mediated therapeutic effects in chronic inflammatory diseases.
    Journal of ethnopharmacology, 2021, Jun-12, Volume: 273

    Topics: Animals; Chronic Disease; Humans; Inflammation; Iridoids; Phytotherapy; Plants

2021

Other Studies

23 other study(ies) available for geniposide and Innate Inflammatory Response

ArticleYear
Synthesis and biological evaluation of geniposide derivatives as inhibitors of hyperuricemia, inflammatory and fibrosis.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Animals; Fibrosis; Hyperuricemia; Inflammation; Iridoids; Kidney Diseases; Mice; Molecular Docking Simulation; Transforming Growth Factor beta; Uric Acid; Xanthine Oxidase

2022
Geniposide Attenuates Hyperglycemia-Induced Oxidative Stress and Inflammation by Activating the Nrf2 Signaling Pathway in Experimental Diabetic Retinopathy.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Ependymoglial Cells; Hyperglycemia; Inflammation; Iridoids; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species

2021
A geniposide-phospholipid complex ameliorates posthyperuricemia chronic kidney disease induced by inflammatory reactions and oxidative stress.
    European journal of pharmacology, 2022, Sep-05, Volume: 930

    Topics: Animals; Inflammation; Iridoids; Kelch-Like ECH-Associated Protein 1; Mice; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phospholipids; Reactive Oxygen Species; Renal Insufficiency, Chronic; Uric Acid

2022
Geniposide promotes splenic Treg differentiation to alleviate colonic inflammation and intestinal barrier injury in ulcerative colitis mice.
    Bioengineered, 2022, Volume: 13, Issue:6

    Topics: Animals; Caco-2 Cells; Cell Differentiation; Colitis, Ulcerative; Disease Models, Animal; Forkhead Transcription Factors; Humans; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Spleen; T-Lymphocytes, Regulatory; Tumor Necrosis Factor-alpha

2022
Geniposide ameliorates dextran sulfate sodium-induced ulcerative colitis via KEAP1-Nrf2 signaling pathway.
    Journal of ethnopharmacology, 2023, Oct-05, Volume: 314

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caco-2 Cells; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Humans; Inflammation; Kelch-Like ECH-Associated Protein 1; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; NF-E2-Related Factor 2; NF-KappaB Inhibitor alpha; Signal Transduction

2023
Geniposide augments apoptosis in fibroblast-like synoviocytes by restoring hypoxia-enhanced JNK-BNIP3-mediated autophagy.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2023, Volume: 72, Issue:8

    Topics: Animals; Apoptosis; Arthritis, Experimental; Autophagy; Fibroblasts; Hyperplasia; Hypoxia; Inflammation; Iridoids; Membrane Proteins; Mitochondrial Proteins; Rats; Synoviocytes

2023
Screening of the Hepatotoxic Components in
    Molecules (Basel, Switzerland), 2019, Oct-30, Volume: 24, Issue:21

    Topics: Animals; Apoptosis; Cell Cycle; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Gardenia; Inflammation; Iridoids; Liver; Molecular Docking Simulation; Oxidative Stress; Phytochemicals; Plant Extracts; Rats; Receptors, Tumor Necrosis Factor, Type I; Reference Standards

2019
Geniposide alleviates non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signalling pathways.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:9

    Topics: AMP-Activated Protein Kinases; Animals; Gene Expression Regulation; Hep G2 Cells; Humans; Inflammation; Iridoids; Lipids; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Palmitic Acid; Phosphatidylinositol 3-Kinases; Phosphorylation; Polyethylene Glycols; Signal Transduction; TOR Serine-Threonine Kinases

2020
miR‑21/PTEN pathway mediates the cardioprotection of geniposide against oxidized low‑density lipoprotein‑induced endothelial injury via suppressing oxidative stress and inflammatory response.
    International journal of molecular medicine, 2020, Volume: 45, Issue:5

    Topics: Antioxidants; Apoptosis; Cardiotonic Agents; Cell Survival; Cells, Cultured; Cytokines; Down-Regulation; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Iridoids; Lipoproteins, LDL; MicroRNAs; Oxidative Stress; PTEN Phosphohydrolase; Reactive Oxygen Species; Signal Transduction; Up-Regulation

2020
Geniposide ameliorated sepsis-induced acute kidney injury by activating PPARγ.
    Aging, 2020, 11-10, Volume: 12, Issue:22

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cells, Cultured; Inflammation; Iridoids; Kidney; Male; Mice, Inbred BALB C; Oxidative Stress; PPAR gamma; Sepsis

2020
Using Network Pharmacology for Systematic Understanding of Geniposide in Ameliorating Inflammatory Responses in Colitis Through Suppression of NLRP3 Inflammasome in Macrophage by AMPK/Sirt1 Dependent Signaling.
    The American journal of Chinese medicine, 2020, Volume: 48, Issue:7

    Topics: AMP-Activated Protein Kinases; Animals; Cells, Cultured; Colitis; Disease Models, Animal; Inflammasomes; Inflammation; Iridoids; Macrophages; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Phytotherapy; RAW 264.7 Cells; Signal Transduction; Sirtuin 1

2020
Effect of genipin-1-β-d-gentiobioside on diabetic nephropathy in mice by activating AMP-activated protein kinase/silencing information regulator-related enzyme 1/ nuclear factor-κB pathway.
    The Journal of pharmacy and pharmacology, 2021, Aug-12, Volume: 73, Issue:9

    Topics: AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gardenia; Inflammation; Iridoids; Kidney; Male; Mice, Inbred C57BL; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Phytotherapy; Plant Extracts; Podocytes; Sirtuin 1

2021
Baicalin and Geniposide Inhibit Polarization and Inflammatory Injury of OGD/R-Treated Microglia by Suppressing the 5-LOX/LTB4 Pathway.
    Neurochemical research, 2021, Volume: 46, Issue:7

    Topics: Amino Acid Sequence; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Cell Hypoxia; Cell Survival; Cells, Cultured; Epoxide Hydrolases; Flavonoids; Glucose; Humans; Inflammation; Iridoids; Mice; Microglia; Molecular Docking Simulation; Oxygen; Protein Binding; Signal Transduction

2021
Administration of geniposide ameliorates dextran sulfate sodium-induced colitis in mice via inhibition of inflammation and mucosal damage.
    International immunopharmacology, 2017, Volume: 49

    Topics: Animals; Anti-Inflammatory Agents; Caco-2 Cells; Colitis; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Humans; Inflammation; Inflammation Mediators; Intestinal Mucosa; Iridoids; Male; Mice; Mice, Inbred C57BL; NF-kappa B; PPAR gamma; Signal Transduction

2017
Geniposide Suppresses Interleukin-1β-Induced Inflammation and Apoptosis in Rat Chondrocytes via the PI3K/Akt/NF-κB Signaling Pathway.
    Inflammation, 2018, Volume: 41, Issue:2

    Topics: Animals; Apoptosis; Chondrocytes; Inflammation; Interleukin-1beta; Iridoids; NF-kappa B; Osteoarthritis; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction

2018
Geniposide Attenuates LPS-Induced Injury via Up-Regulation of miR-145 in H9c2 Cells.
    Inflammation, 2018, Volume: 41, Issue:4

    Topics: Animals; Cell Line; Cell Survival; Inflammation; Iridoids; Lipopolysaccharides; MAP Kinase Signaling System; MicroRNAs; Myocytes, Cardiac; Rats; Up-Regulation

2018
Anti-Inflammatory Effect of Geniposide on Osteoarthritis by Suppressing the Activation of p38 MAPK Signaling Pathway.
    BioMed research international, 2018, Volume: 2018

    Topics: Animals; Anti-Inflammatory Agents; Chondrocytes; Inflammation; Interleukin-1beta; Iridoids; Matrix Metalloproteinases; Nitric Oxide; Osteoarthritis; p38 Mitogen-Activated Protein Kinases; Rabbits; Signal Transduction; Synovial Fluid; Tumor Necrosis Factor-alpha

2018
Geniposide Protects against Obesity-Related Cardiac Injury through AMPK
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Cardiomegaly; Diet, High-Fat; Heart; Inflammation; Iridoids; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Obesity; Signal Transduction; Sirtuin 1

2018
Geniposide protects PC12 cells from lipopolysaccharide-evoked inflammatory injury via up-regulation of miR-145-5p.
    Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1

    Topics: Animals; Cytokines; Cytoprotection; Inflammation; Iridoids; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; MicroRNAs; NF-kappa B; PC12 Cells; Rats; Signal Transduction; Up-Regulation

2019
Geniposide alleviates inflammation by suppressing MeCP2 in mice with carbon tetrachloride-induced acute liver injury and LPS-treated THP-1 cells.
    International immunopharmacology, 2015, Volume: 29, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Tetrachloride Poisoning; Cell Line; Chemical and Drug Induced Liver Injury; Gene Expression; Gene Knockdown Techniques; Hedgehog Proteins; Inflammation; Interleukin-6; Iridoids; Liver; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; RNA, Small Interfering; Tumor Necrosis Factor-alpha

2015
Geniposide attenuates inflammatory response by suppressing P2Y14 receptor and downstream ERK1/2 signaling pathway in oxygen and glucose deprivation-induced brain microvascular endothelial cells.
    Journal of ethnopharmacology, 2016, Jun-05, Volume: 185

    Topics: Animals; Cells, Cultured; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Glucose; Inflammation; Iridoids; Oxygen; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y; Signal Transduction

2016
Geniposide reduces inflammatory responses of oxygen-glucose deprived rat microglial cells via inhibition of the TLR4 signaling pathway.
    Neurochemical research, 2012, Volume: 37, Issue:10

    Topics: Animals; Culture Media; Cytokines; Dose-Response Relationship, Drug; Glucose; Inflammation; Iridoids; Male; Microglia; Oxygen; Rats; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4

2012
Anti-inflammatory evaluation of gardenia extract, geniposide and genipin.
    Journal of ethnopharmacology, 2006, Feb-20, Volume: 103, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Dose-Response Relationship, Drug; Edema; Female; Fruit; Gardenia; Inflammation; Iridoid Glycosides; Iridoids; Male; Mice; Nitrates; Plant Extracts; Pyrans; Rats; Rats, Sprague-Dawley

2006