gemfibrozil has been researched along with Myocardial Ischemia in 8 studies
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gemfibrozil-statin combination therapy is a well-known risk factor for myopathy and rhabdomyolysis." | 7.70 | A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy--a case report. ( Boran, M; Gökçe, V; Koçak, B; Korkmaz, S; Ozdemir, O; Uzun, Y, 2000) |
| " The three groups were similar for age, sex and geographical region, but significantly more patients on bezafibrate had diabetes and/or hypertension than those on gemfibrozil or simvastatin." | 3.70 | A comparison of the use, effectiveness and safety of bezafibrate, gemfibrozil and simvastatin in normal clinical practice using the New Zealand Intensive Medicines Monitoring Programme (IMMP). ( Beggs, PW; Clark, DW; Coulter, DM; Williams, SM, 1999) |
| "Gemfibrozil-statin combination therapy is a well-known risk factor for myopathy and rhabdomyolysis." | 3.70 | A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy--a case report. ( Boran, M; Gökçe, V; Koçak, B; Korkmaz, S; Ozdemir, O; Uzun, Y, 2000) |
| "A decision to treat hyperlipidemias would be based on the assumption that such disorders lead to accelerated atherogenesis and ultimately to cardiac dysfunction." | 1.30 | Lack of left ventricular dysfunction associated with sustained exposure to hyperlipidemia following lung transplantation. ( Kesten, S; Maurer, J; Mayne, L; Scavuzzo, M, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, H | 1 |
| Liu, LL | 1 |
| Ye, LL | 1 |
| McGuckin, C | 1 |
| Tamowski, S | 1 |
| Scowen, P | 1 |
| Tian, H | 1 |
| Murray, K | 1 |
| Hatton, WJ | 1 |
| Duan, D | 1 |
| Milionis, HJ | 2 |
| Elisaf, MS | 1 |
| Mikhailidis, DP | 2 |
| Gami, A | 1 |
| Gault, MH | 1 |
| Longerich, LL | 1 |
| Purchase, L | 1 |
| Harnett, J | 1 |
| Breckenridge, C | 1 |
| Kesten, S | 1 |
| Mayne, L | 1 |
| Scavuzzo, M | 1 |
| Maurer, J | 1 |
| Beggs, PW | 1 |
| Clark, DW | 1 |
| Williams, SM | 1 |
| Coulter, DM | 1 |
| Ozdemir, O | 1 |
| Boran, M | 1 |
| Gökçe, V | 1 |
| Uzun, Y | 1 |
| Koçak, B | 1 |
| Korkmaz, S | 1 |
| Rizos, E | 1 |
3 reviews available for gemfibrozil and Myocardial Ischemia
| Article | Year |
|---|---|
Treatment of dyslipidaemias in patients with established vascular disease: a revival of the fibrates.
Topics: Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Clofibric Acid; Gemfibrozil; Humans; Hydroxymethylg | 2000 |
Secondary prevention of ischaemic cardiac events.
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitor | 2006 |
Smoking diminishes the beneficial effect of statins: observations from the landmark trials.
Topics: Anticholesteremic Agents; Clinical Trials as Topic; Gemfibrozil; Humans; Lovastatin; Myocardial Isch | 2001 |
5 other studies available for gemfibrozil and Myocardial Ischemia
| Article | Year |
|---|---|
Targeted inactivation of cystic fibrosis transmembrane conductance regulator chloride channel gene prevents ischemic preconditioning in isolated mouse heart.
Topics: Animals; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Gemfibrozil; Ion Transport; | 2004 |
Comparison of Lp(a) concentrations and some potential effects in hemodialysis, CAPD, transplantation, and control groups, and review of the literature.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Apolipoprotein B-100; Apolipoproteins A; Apolipoproteins | 1995 |
Lack of left ventricular dysfunction associated with sustained exposure to hyperlipidemia following lung transplantation.
Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Cholestyramine Resin; Echocardiography; Fem | 1997 |
A comparison of the use, effectiveness and safety of bezafibrate, gemfibrozil and simvastatin in normal clinical practice using the New Zealand Intensive Medicines Monitoring Programme (IMMP).
Topics: Bezafibrate; Cohort Studies; Comorbidity; Diabetes Complications; Female; Gemfibrozil; Humans; Hyper | 1999 |
A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy--a case report.
Topics: Diabetes Mellitus; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Fatal Outcome; | 2000 |