Page last updated: 2024-10-27

gemfibrozil and Melanoma

gemfibrozil has been researched along with Melanoma in 3 studies

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"The aim of this report was to describe a potential drug-drug interaction between IFN alfa-2b and gemfibrozil in a patient with malignant melanoma."7.73Potential drug-drug interaction between interferon alfa-2b and gemfibrozil in a patient with malignant melanoma. ( Jakowatz, JG; Taheri, R; Wong, SF, 2005)
"Large randomized, controlled clinical trials of lovastatin and gemfibrozil for heart disease prevention have reported statistically significantly lower melanoma incidences in persons receiving these medications."4.83Statins, fibrates, and melanoma risk: a systematic review and meta-analysis. ( Dellavalle, RP; Drake, AL; Freeman, SR; Graber, M; Heilig, LF; McNealy, K; Schilling, LM, 2006)
"The aim of this report was to describe a potential drug-drug interaction between IFN alfa-2b and gemfibrozil in a patient with malignant melanoma."3.73Potential drug-drug interaction between interferon alfa-2b and gemfibrozil in a patient with malignant melanoma. ( Jakowatz, JG; Taheri, R; Wong, SF, 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wong, SF1
Jakowatz, JG1
Taheri, R1
Grubisić-Cabo, F1
Vrdoljak, E1
Freeman, SR1
Drake, AL1
Heilig, LF1
Graber, M1
McNealy, K1
Schilling, LM1
Dellavalle, RP1

Reviews

1 review available for gemfibrozil and Melanoma

ArticleYear
Statins, fibrates, and melanoma risk: a systematic review and meta-analysis.
    Journal of the National Cancer Institute, 2006, Nov-01, Volume: 98, Issue:21

    Topics: Atorvastatin; Bezafibrate; Clofibrate; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-C

2006

Other Studies

2 other studies available for gemfibrozil and Melanoma

ArticleYear
Potential drug-drug interaction between interferon alfa-2b and gemfibrozil in a patient with malignant melanoma.
    Clinical therapeutics, 2005, Volume: 27, Issue:12

    Topics: Adult; Antineoplastic Agents; Chemotherapy, Adjuvant; Drug Interactions; Gemfibrozil; Humans; Hypert

2005
Drug-induced hepatitis in a patient with malignant melanoma treated with interferon alfa 2b adjuvantly who had been administered gemfibrozil in therapy.
    Medical oncology (Northwood, London, England), 2006, Volume: 23, Issue:1

    Topics: Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Drug Interactions; Female; Gemfibrozi

2006