Page last updated: 2024-10-27

gemfibrozil and Experimental Hepatoma

gemfibrozil has been researched along with Experimental Hepatoma in 4 studies

Research Excerpts

ExcerptRelevanceReference
" Chemical-specific and mechanistic data support concordance of temporal and dose-response relationships for the key events associated with many PPARα activators including a phthalate ester plasticizer di(2-ethylhexyl) phthalate (DEHP) and the drug gemfibrozil."2.50Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study. ( Corton, JC; Cunningham, ML; Hummer, BT; Klaunig, JE; Lau, C; Meek, B; Peters, JM; Popp, JA; Rhomberg, L; Seed, J, 2014)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corton, JC1
Cunningham, ML1
Hummer, BT1
Lau, C1
Meek, B1
Peters, JM1
Popp, JA1
Rhomberg, L1
Seed, J1
Klaunig, JE1
Fitzgerald, JE1
Sanyer, JL1
Schardein, JL1
Lake, RS1
McGuire, EJ1
de la Iglesia, FA1
Schoonjans, K1
Staels, B1
Grimaldi, P1
Auwerx, J1
Tam, SP1

Reviews

1 review available for gemfibrozil and Experimental Hepatoma

ArticleYear
Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.
    Critical reviews in toxicology, 2014, Volume: 44, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Diethylhexyl Phthalate; Gemfibrozil; Humans; Liver Ne

2014

Other Studies

3 other studies available for gemfibrozil and Experimental Hepatoma

ArticleYear
Carcinogen bioassay and mutagenicity studies with the hypolipidemic agent gemfibrozil.
    Journal of the National Cancer Institute, 1981, Volume: 67, Issue:5

    Topics: Animals; Biotransformation; Body Weight; Carcinogens; Female; Gemfibrozil; Hypolipidemic Agents; Liv

1981
Acyl-CoA synthetase mRNA expression is controlled by fibric-acid derivatives, feeding and liver proliferation.
    European journal of biochemistry, 1993, Sep-01, Volume: 216, Issue:2

    Topics: Adipose Tissue; Animals; Clofibrate; Coenzyme A Ligases; Diet; Fenofibrate; Gemfibrozil; Gene Expres

1993
Effects of gemfibrozil and ketoconazole on human apolipoprotein AI, B and E levels in two hepatoma cell lines, HepG2 and Hep3B.
    Atherosclerosis, 1991, Volume: 91, Issue:1-2

    Topics: Albumins; Animals; Apolipoprotein A-I; Apolipoproteins; Apolipoproteins B; Apolipoproteins E; Cell L

1991