gemfibrozil has been researched along with Experimental Hepatoma in 4 studies
Excerpt | Relevance | Reference |
---|---|---|
" Chemical-specific and mechanistic data support concordance of temporal and dose-response relationships for the key events associated with many PPARα activators including a phthalate ester plasticizer di(2-ethylhexyl) phthalate (DEHP) and the drug gemfibrozil." | 2.50 | Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study. ( Corton, JC; Cunningham, ML; Hummer, BT; Klaunig, JE; Lau, C; Meek, B; Peters, JM; Popp, JA; Rhomberg, L; Seed, J, 2014) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (25.00) | 18.7374 |
1990's | 2 (50.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Corton, JC | 1 |
Cunningham, ML | 1 |
Hummer, BT | 1 |
Lau, C | 1 |
Meek, B | 1 |
Peters, JM | 1 |
Popp, JA | 1 |
Rhomberg, L | 1 |
Seed, J | 1 |
Klaunig, JE | 1 |
Fitzgerald, JE | 1 |
Sanyer, JL | 1 |
Schardein, JL | 1 |
Lake, RS | 1 |
McGuire, EJ | 1 |
de la Iglesia, FA | 1 |
Schoonjans, K | 1 |
Staels, B | 1 |
Grimaldi, P | 1 |
Auwerx, J | 1 |
Tam, SP | 1 |
1 review available for gemfibrozil and Experimental Hepatoma
Article | Year |
---|---|
Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Diethylhexyl Phthalate; Gemfibrozil; Humans; Liver Ne | 2014 |
3 other studies available for gemfibrozil and Experimental Hepatoma
Article | Year |
---|---|
Carcinogen bioassay and mutagenicity studies with the hypolipidemic agent gemfibrozil.
Topics: Animals; Biotransformation; Body Weight; Carcinogens; Female; Gemfibrozil; Hypolipidemic Agents; Liv | 1981 |
Acyl-CoA synthetase mRNA expression is controlled by fibric-acid derivatives, feeding and liver proliferation.
Topics: Adipose Tissue; Animals; Clofibrate; Coenzyme A Ligases; Diet; Fenofibrate; Gemfibrozil; Gene Expres | 1993 |
Effects of gemfibrozil and ketoconazole on human apolipoprotein AI, B and E levels in two hepatoma cell lines, HepG2 and Hep3B.
Topics: Albumins; Animals; Apolipoprotein A-I; Apolipoproteins; Apolipoproteins B; Apolipoproteins E; Cell L | 1991 |