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gemfibrozil and Diabetes Mellitus

gemfibrozil has been researched along with Diabetes Mellitus in 18 studies

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
"In a double-blind, randomized crossover study, 29 patients with non-insulin-dependent diabetes mellitus (NIDDM) and hyperlipoproteinemia were treated with gemfibrozil (1,200 mg/d) or simvastatin (10 mg/d) for 4 months."9.08A comparison between the effects of gemfibrozil and simvastatin on insulin sensitivity in patients with non-insulin-dependent diabetes mellitus and hyperlipoproteinemia. ( Johansson, J; Lithell, H; Ohrvall, M; Vessby, B, 1995)
"Gemfibrozil-statin combination therapy is a well-known risk factor for myopathy and rhabdomyolysis."7.70A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy--a case report. ( Boran, M; Gökçe, V; Koçak, B; Korkmaz, S; Ozdemir, O; Uzun, Y, 2000)
"In a double-blind, randomized crossover study, 29 patients with non-insulin-dependent diabetes mellitus (NIDDM) and hyperlipoproteinemia were treated with gemfibrozil (1,200 mg/d) or simvastatin (10 mg/d) for 4 months."5.08A comparison between the effects of gemfibrozil and simvastatin on insulin sensitivity in patients with non-insulin-dependent diabetes mellitus and hyperlipoproteinemia. ( Johansson, J; Lithell, H; Ohrvall, M; Vessby, B, 1995)
"Gemfibrozil-statin combination therapy is a well-known risk factor for myopathy and rhabdomyolysis."3.70A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy--a case report. ( Boran, M; Gökçe, V; Koçak, B; Korkmaz, S; Ozdemir, O; Uzun, Y, 2000)
"Since dyslipidemia is common in diabetes and is associated with increased cardiovascular risk, we tested the hypothesis that Thr-54 is associated with increased cardiovascular risk in patients with diabetes."2.73Codon 54 polymorphism of the fatty acid binding protein (FABP) 2 gene is associated with increased cardiovascular risk in the dyslipidemic diabetic participants of the Veterans Affairs HDL intervention trial (VA-HIT). ( Bloomfield, H; Brousseau, ME; Collins, D; Georgopoulos, A; O'Connor, JJ; Ordovas, JM; Robins, SJ; Schaefer, EJ, 2007)
"The gemfibrozil was well tolerated."2.65The effect of gemfibrozil on serum lipids in diabetic patients. ( Konttinen, A; Kuisma, I; Ojala, K; Pohjola, S; Ralli, R, 1979)
"Hypertriglyceridemia is commonly embedded in the context of a metabolic syndrome that includes central obesity, insulin resistance, low levels of HDL cholesterol, and often hypertension."2.41A risk factor for atherosclerosis: triglyceride-rich lipoproteins. ( Kane, JP; Malloy, MJ, 2001)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's2 (11.11)18.2507
2000's9 (50.00)29.6817
2010's4 (22.22)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Zhang, Y1
Song, H1
Bai, J1
Xiu, J1
Wu, G1
Zhang, L1
Wu, Y1
Qu, Y1
Kayıkçıoğlu, M1
Shahbazova, S1
İbrahimov, F1
Can, LH1
King, D1
Armstrong, MJ1
Khoshakhlagh, AH1
Yazdanirad, S1
Laal, F1
Sarsangi, V1
Bloomgarden, ZT1
Drexler, A1
Lee, CY1
Huang, KH1
Lin, CC1
Tsai, TH1
Shih, HC1
Angulo, P1
Davidson, MH1
Ganda, OP1
Kon, YC1
Tai, ES1
Collins, D2
Robins, SJ2
O'Connor, JJ2
Bloomfield, HE1
Ordovas, JM2
Schaefer, EJ2
Brousseau, ME2
Trivedi, NR1
Cong, Z1
Nelson, AM1
Albert, AJ1
Rosamilia, LL1
Sivarajah, S1
Gilliland, KL1
Liu, W1
Mauger, DT1
Gabbay, RA1
Thiboutot, DM1
Georgopoulos, A1
Bloomfield, H1
Ohrvall, M1
Lithell, H1
Johansson, J1
Vessby, B1
Bell, DS1
Ovalle, F1
Ozdemir, O1
Boran, M1
Gökçe, V1
Uzun, Y1
Koçak, B1
Korkmaz, S1
Malloy, MJ1
Kane, JP1
Konttinen, A1
Kuisma, I1
Ralli, R1
Pohjola, S1
Ojala, K1

Reviews

5 reviews available for gemfibrozil and Diabetes Mellitus

ArticleYear
Overview of Gilbert's syndrome.
    Drug and therapeutics bulletin, 2019, Volume: 57, Issue:2

    Topics: Antineoplastic Agents; Comorbidity; Contraindications, Drug; Diabetes Mellitus; Drug Therapy, Combin

2019
Current best treatment for non-alcoholic fatty liver disease.
    Expert opinion on pharmacotherapy, 2003, Volume: 4, Issue:5

    Topics: Antioxidants; Chromans; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Fatty L

2003
Combination lipid-lowering therapy in diabetes.
    Current diabetes reports, 2003, Volume: 3, Issue:3

    Topics: Diabetes Mellitus; Drug Therapy, Combination; Fenofibrate; Gemfibrozil; Humans; Hydroxymethylglutary

2003
The role of lipid management in diabetes.
    Cardiology clinics, 2005, Volume: 23, Issue:2

    Topics: Anticholesteremic Agents; Atorvastatin; Diabetes Mellitus; Diabetic Angiopathies; Gemfibrozil; Hepta

2005
A risk factor for atherosclerosis: triglyceride-rich lipoproteins.
    Advances in internal medicine, 2001, Volume: 47

    Topics: Coronary Artery Disease; Diabetes Mellitus; Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxym

2001

Trials

5 trials available for gemfibrozil and Diabetes Mellitus

ArticleYear
The L162V polymorphism at the peroxisome proliferator activated receptor alpha locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus: the Veterans Affairs HDL Intervention Trial (VA-HIT).
    Atherosclerosis, 2006, Volume: 187, Issue:1

    Topics: Alleles; Cardiovascular Diseases; Cholesterol, HDL; Diabetes Complications; Diabetes Mellitus; Gemfi

2006
Peroxisome proliferator-activated receptors increase human sebum production.
    The Journal of investigative dermatology, 2006, Volume: 126, Issue:9

    Topics: Adult; Cell Line, Transformed; Diabetes Mellitus; Female; Fenofibrate; Gemfibrozil; Humans; Hyperlip

2006
Codon 54 polymorphism of the fatty acid binding protein (FABP) 2 gene is associated with increased cardiovascular risk in the dyslipidemic diabetic participants of the Veterans Affairs HDL intervention trial (VA-HIT).
    Atherosclerosis, 2007, Volume: 194, Issue:1

    Topics: Aged; Codon; Diabetes Mellitus; Dyslipidemias; Fatty Acid-Binding Proteins; Gemfibrozil; Genetic Pre

2007
A comparison between the effects of gemfibrozil and simvastatin on insulin sensitivity in patients with non-insulin-dependent diabetes mellitus and hyperlipoproteinemia.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:2

    Topics: Aged; Body Weight; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Female; Gemfibroz

1995
The effect of gemfibrozil on serum lipids in diabetic patients.
    Annals of clinical research, 1979, Volume: 11, Issue:6

    Topics: Administration, Oral; Adult; Aged; Blood Glucose; Cholesterol; Clinical Trials as Topic; Diabetes Me

1979

Other Studies

8 other studies available for gemfibrozil and Diabetes Mellitus

ArticleYear
Association between the stress hyperglycemia ratio and severity of coronary artery disease under different glucose metabolic states.
    Cardiovascular diabetology, 2023, 02-08, Volume: 22, Issue:1

    Topics: Coronary Angiography; Coronary Artery Disease; Diabetes Mellitus; Gemfibrozil; Glucose; Humans; Hype

2023
Cumulative non-HDL-cholesterol burden in patients with hypertriglyceridemia receiving long-term fibrate therapy: Real life data from a lipid clinic cohort.
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2020, Volume: 48, Issue:4

    Topics: Adult; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cost of Illness; Di

2020
The relationship between illnesses and medical drug consumption with the occurrence of traffic accidents among truck and bus drivers in Tehran, Iran.
    Chinese journal of traumatology = Zhonghua chuang shang za zhi, 2019, Volume: 22, Issue:3

    Topics: Accidents, Traffic; Adult; Automobile Driving; Cross-Sectional Studies; Diabetes Mellitus; Drug Util

2019
Fibrate use in diabetes: new concepts.
    Journal of diabetes, 2011, Volume: 3, Issue:1

    Topics: Bezafibrate; Cardiovascular Diseases; Diabetes Mellitus; Fenofibrate; Fibric Acids; Gemfibrozil; Hum

2011
A neutral risk on the development of new-onset diabetes mellitus (NODM) in Taiwanese patients with dyslipidaemia treated with fibrates.
    TheScientificWorldJournal, 2012, Volume: 2012

    Topics: Adult; Diabetes Complications; Diabetes Mellitus; Dyslipidemias; Female; Fenofibrate; Gemfibrozil; H

2012
High-density lipoprotein cholesterol: ready for prime time?
    Singapore medical journal, 2005, Volume: 46, Issue:10

    Topics: Cardiovascular Diseases; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Ch

2005
Troglitazone interferes with gemfibrozil's lipid-lowering action.
    Diabetes care, 1998, Volume: 21, Issue:11

    Topics: Chromans; Diabetes Mellitus; Drug Interactions; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reduc

1998
A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy--a case report.
    Angiology, 2000, Volume: 51, Issue:8

    Topics: Diabetes Mellitus; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Fatal Outcome;

2000