Page last updated: 2024-10-27

gemfibrozil and Alzheimer Disease

gemfibrozil has been researched along with Alzheimer Disease in 2 studies

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research Excerpts

ExcerptRelevanceReference
"Gemfibrozil is a drug that has been used for over 40 years to lower triglycerides in blood."1.91Gemfibrozil-Induced Intracellular Triglyceride Increase in SH-SY5Y, HEK and Calu-3 Cells. ( Bachmann, CM; Erhardt, T; Grimm, HS; Grimm, MOW; Hartmann, T; Janitschke, D; Lauer, AA, 2023)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Xu, J3
Mao, C3
Hou, Y3
Luo, Y3
Binder, JL3
Zhou, Y3
Bekris, LM3
Shin, J3
Hu, M3
Wang, F3
Eng, C3
Oprea, TI3
Flanagan, ME3
Pieper, AA3
Cummings, J3
Leverenz, JB3
Cheng, F3
Bachmann, CM1
Janitschke, D1
Lauer, AA1
Erhardt, T1
Hartmann, T1
Grimm, MOW1
Grimm, HS1

Other Studies

2 other studies available for gemfibrozil and Alzheimer Disease

ArticleYear
Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease.
    Cell reports, 2022, 11-29, Volume: 41, Issue:9

    Topics: Alzheimer Disease; Deep Learning; Drug Repositioning; Gemfibrozil; Genome-Wide Association Study; Hu

2022
Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease.
    Cell reports, 2022, 11-29, Volume: 41, Issue:9

    Topics: Alzheimer Disease; Deep Learning; Drug Repositioning; Gemfibrozil; Genome-Wide Association Study; Hu

2022
Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease.
    Cell reports, 2022, 11-29, Volume: 41, Issue:9

    Topics: Alzheimer Disease; Deep Learning; Drug Repositioning; Gemfibrozil; Genome-Wide Association Study; Hu

2022
Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease.
    Cell reports, 2022, 11-29, Volume: 41, Issue:9

    Topics: Alzheimer Disease; Deep Learning; Drug Repositioning; Gemfibrozil; Genome-Wide Association Study; Hu

2022
Gemfibrozil-Induced Intracellular Triglyceride Increase in SH-SY5Y, HEK and Calu-3 Cells.
    International journal of molecular sciences, 2023, Feb-03, Volume: 24, Issue:3

    Topics: Alzheimer Disease; Fatty Acids; Gemfibrozil; Humans; Hypolipidemic Agents; Neuroblastoma; Triglyceri

2023