Page last updated: 2024-10-27

gemfibrozil and Alloxan Diabetes

gemfibrozil has been researched along with Alloxan Diabetes in 7 studies

Research Excerpts

ExcerptRelevanceReference
"Gemfibrozil is a PPAR-α ligand that inhibits the progression of atherosclerosis in insulin resistance type 2 diabetes mellitus (IR type 2 DM)."3.79Gemfibrozil and its combination with metformin on pleiotropic effect on IL-10 and adiponectin and anti-atherogenic treatment in insulin resistant type 2 diabetes mellitus rats. ( Kurmi, MK; Raikwar, SK; Sharma, AK; Srinivasan, BP, 2013)
" In a twelve-week study, chronic administration of 3b in db/db mice resulted in sustained glycemic control, to a greater extent than liraglutide and semaglutide."1.56Rational design and biological evaluation of gemfibrozil modified Xenopus GLP-1 derivatives as long-acting hypoglycemic agents. ( Chen, X; Fu, J; Han, J; Li, C; Yang, Q; Yin, J; Zhou, F, 2020)
"Gemfibrozil treatment restored the endothelium-dependent responses to acetylcholine in diabetic rats."1.32Effects of gemfibrozil treatment on vascular reactivity of streptozotocin-diabetic rat aorta. ( Akin, FB; Ozansoy, G, 2004)
"Gemfibrozil treatment had no effect on blood glucose, plasma insulin and vessel antioxidant enzyme activity of diabetic animals."1.31Short-term gemfibrozil treatment reverses lipid profile and peroxidation but does not alter blood glucose and tissue antioxidant enzymes in chronically diabetic rats. ( Akin, B; Aktan, F; Karasu, C; Ozansoy, G, 2001)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Kumar, A2
Maurya, RA2
Sharma, S2
Ahmad, P1
Singh, AB1
Bhatia, G2
Srivastava, AK2
Tripathi, VD1
Srivastava, SP1
Tamrakar, AK1
Han, J1
Fu, J1
Yang, Q1
Zhou, F1
Chen, X1
Li, C1
Yin, J1
Sharma, AK1
Raikwar, SK1
Kurmi, MK1
Srinivasan, BP1
Ozansoy, G2
Akin, FB1
Calkin, AC1
Cooper, ME1
Jandeleit-Dahm, KA1
Allen, TJ1
Akin, B1
Aktan, F1
Karasu, C1

Other Studies

7 other studies available for gemfibrozil and Alloxan Diabetes

ArticleYear
Pyranocoumarins: a new class of anti-hyperglycemic and anti-dyslipidemic agents.
    Bioorganic & medicinal chemistry letters, 2009, Nov-15, Volume: 19, Issue:22

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dyslipidemias; Hypoglycemic Agents; Lipid M

2009
Design and synthesis of 2,4-disubstituted polyhydroquinolines as prospective antihyperglycemic and lipid modulating agents.
    Bioorganic & medicinal chemistry, 2010, Jun-01, Volume: 18, Issue:11

    Topics: Animals; Diabetes Mellitus, Experimental; Drug Design; Dyslipidemias; Glycogen Phosphorylase; Hypogl

2010
Rational design and biological evaluation of gemfibrozil modified Xenopus GLP-1 derivatives as long-acting hypoglycemic agents.
    European journal of medicinal chemistry, 2020, Jul-15, Volume: 198

    Topics: Albumins; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-R

2020
Gemfibrozil and its combination with metformin on pleiotropic effect on IL-10 and adiponectin and anti-atherogenic treatment in insulin resistant type 2 diabetes mellitus rats.
    Inflammopharmacology, 2013, Volume: 21, Issue:2

    Topics: Adiponectin; Animals; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug

2013
Effects of gemfibrozil treatment on vascular reactivity of streptozotocin-diabetic rat aorta.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:2

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol,

2004
Gemfibrozil decreases atherosclerosis in experimental diabetes in association with a reduction in oxidative stress and inflammation.
    Diabetologia, 2006, Volume: 49, Issue:4

    Topics: Angiotensins; Animals; Apolipoproteins E; Atherosclerosis; Biomarkers; Diabetes Mellitus, Experiment

2006
Short-term gemfibrozil treatment reverses lipid profile and peroxidation but does not alter blood glucose and tissue antioxidant enzymes in chronically diabetic rats.
    Molecular and cellular biochemistry, 2001, Volume: 216, Issue:1-2

    Topics: Animals; Antioxidants; Aorta; Blood Glucose; Body Weight; Catalase; Cholesterol; Diabetes Mellitus,

2001