gemfibrozil and Allergic Encephalomyelitis

gemfibrozil has been researched along with Allergic Encephalomyelitis in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ben, LH; Drew, PD; Gocke, AR; Hussain, RZ; Lovett-Racke, AE; Peng, H; Racke, MK; Stuve, O; Weiner, J; Yang, Y1
Gonzalez, FJ; Jana, M; Mondal, S; Pahan, K1
Chavis, JA; Choy, J; Diab, A; Drew, PD; Hussain, RZ; Lovett-Racke, AE; Matthes, L; Northrop, S; Racke, MK; Rocchini, A1
Dasgupta, S; Hartley, DM; Jana, M; Pahan, K; Roy, A1

Trials

1 trial(s) available for gemfibrozil and Allergic Encephalomyelitis

ArticleYear
Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-β.
    The Journal of biological chemistry, 2012, Oct-05, Volume: 287, Issue:41

    Topics: Animals; Cells, Cultured; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Gemfibrozil; Gene Expression Regulation; Humans; Hypolipidemic Agents; Mice; Mice, Knockout; Myelin Sheath; Nerve Tissue Proteins; Oligodendroglia; PPAR gamma; PPAR-beta; Response Elements

2012

Other Studies

3 other study(ies) available for gemfibrozil and Allergic Encephalomyelitis

ArticleYear
Transcriptional modulation of the immune response by peroxisome proliferator-activated receptor-{alpha} agonists in autoimmune disease.
    Journal of immunology (Baltimore, Md. : 1950), 2009, Apr-01, Volume: 182, Issue:7

    Topics: Animals; Blotting, Western; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Fenofibrate; GATA3 Transcription Factor; Gemfibrozil; Gene Expression Regulation; Immunologic Factors; Interleukin-4; Interleukin-5; Mice; Mice, Transgenic; PPAR alpha; Promoter Regions, Genetic; T-Box Domain Proteins; Transcription, Genetic; Transfection

2009
Peroxisome proliferator-activated receptor alpha agonists as therapy for autoimmune disease.
    Journal of immunology (Baltimore, Md. : 1950), 2004, May-01, Volume: 172, Issue:9

    Topics: Animals; Cell Line; Cell Line, Transformed; Cell Survival; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Fenofibrate; Gemfibrozil; Growth Inhibitors; Humans; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbodies; Microglia; Nitric Oxide; Receptors, Cytoplasmic and Nuclear; T-Lymphocyte Subsets; Th2 Cells; Transcription Factors

2004
Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha.
    Molecular pharmacology, 2007, Volume: 72, Issue:4

    Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Female; GATA3 Transcription Factor; Gemfibrozil; Hypolipidemic Agents; Interferon-gamma; Interleukin-4; Male; Mice; Mice, Knockout; PPAR alpha; Th1 Cells; Th2 Cells

2007