Page last updated: 2024-10-27

gemfibrozil and Allergic Encephalomyelitis

gemfibrozil has been researched along with Allergic Encephalomyelitis in 4 studies

Research Excerpts

ExcerptRelevanceReference
"The present study underlines the importance of gemfibrozil, a lipid-lowering drug and an activator of peroxisome proliferator-activated receptor-alpha (PPAR-alpha), in inhibiting the disease process of adoptively transferred experimental allergic encephalomyelitis (EAE), an animal model of relapsing-remitting multiple sclerosis."3.74Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha. ( Dasgupta, S; Hartley, DM; Jana, M; Pahan, K; Roy, A, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gocke, AR1
Hussain, RZ2
Yang, Y1
Peng, H1
Weiner, J1
Ben, LH1
Drew, PD2
Stuve, O1
Lovett-Racke, AE2
Racke, MK2
Jana, M2
Mondal, S1
Gonzalez, FJ1
Pahan, K2
Northrop, S1
Choy, J1
Rocchini, A1
Matthes, L1
Chavis, JA1
Diab, A1
Dasgupta, S1
Roy, A1
Hartley, DM1

Trials

1 trial available for gemfibrozil and Allergic Encephalomyelitis

ArticleYear
Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-β.
    The Journal of biological chemistry, 2012, Oct-05, Volume: 287, Issue:41

    Topics: Animals; Cells, Cultured; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Gemfi

2012

Other Studies

3 other studies available for gemfibrozil and Allergic Encephalomyelitis

ArticleYear
Transcriptional modulation of the immune response by peroxisome proliferator-activated receptor-{alpha} agonists in autoimmune disease.
    Journal of immunology (Baltimore, Md. : 1950), 2009, Apr-01, Volume: 182, Issue:7

    Topics: Animals; Blotting, Western; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Im

2009
Peroxisome proliferator-activated receptor alpha agonists as therapy for autoimmune disease.
    Journal of immunology (Baltimore, Md. : 1950), 2004, May-01, Volume: 172, Issue:9

    Topics: Animals; Cell Line; Cell Line, Transformed; Cell Survival; Cells, Cultured; Cytokines; Dose-Response

2004
Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha.
    Molecular pharmacology, 2007, Volume: 72, Issue:4

    Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Female; GATA3 Transcription Factor; Gemfibrozi

2007