gemeprost and Abnormalities--Multiple

gemeprost has been researched along with Abnormalities--Multiple* in 2 studies

Other Studies

2 other study(ies) available for gemeprost and Abnormalities--Multiple

ArticleYear
Second trimester termination of pregnancy for fetal anomaly or death: comparing mifepristone/misoprostol to gemeprost.
    European journal of obstetrics, gynecology, and reproductive biology, 2001, Volume: 95, Issue:1

    To assess the effect of changing the regimen for second trimester induction of labour from gemeprost to mifepristone/misoprostol.. A retrospective study at a university teaching hospital over the 5-year period 1993-1997. SUBJECTS, METHODS and REGIMENS: 68 patients, 34 in the gemeprost group and 34 in the mifepristone/misoprostol group. The gemeprost group received 1mg vaginally every 3h to a maximum of five doses. The mifepristone/misoprostol group were pre-treated with 600 mg mifepristone orally followed by 800 microg misoprostol vaginally and then 400 microg orally every 3h to a maximum of four oral doses.. Induction to abortion interval; delivery within 24h.. The mifepristone/misoprostol group had a lower induction to abortion interval compared to the gemeprost group (median 8.9h versus 19.8h, respectively, p<0.01). The mifepristone/misoprostol regimen was more successful than the gemeprost regimen; 94% versus 68%, respectively, aborted without extra medical or surgical intervention, p=0.02. There were no significant differences in side effects, analgesia requirements or complications between the two groups. Three patients with previous Caesarean sections had a ruptured uterus; two from the gemeprost group and one from the mifepristone/misoprostol group.. The new mifepristone/misoprostol regimen was more effective in second trimester induction of labour. Induction of labour with misoprostol or gemeprost should be used with care in patients with a previous Caesarean section.

    Topics: Abnormalities, Multiple; Abortifacient Agents, Nonsteroidal; Abortion, Therapeutic; Administration, Intravaginal; Administration, Oral; Adult; Alprostadil; Female; Fetal Death; Humans; Maternal Age; Middle Aged; Mifepristone; Misoprostol; Pregnancy; Pregnancy Trimester, Second; Reproductive History; Retrospective Studies; Treatment Outcome

2001
Multiple fetal anomalies in the first trimester; detection using transvaginal ultrasound and therapeutic abortion using mifepristone (RU486) in conjunction with gemeprost vaginal pessaries.
    British journal of obstetrics and gynaecology, 1992, Volume: 99, Issue:3

    Topics: Abnormalities, Multiple; Abortifacient Agents, Nonsteroidal; Abortion, Therapeutic; Administration, Oral; Adult; Alprostadil; Female; Humans; Mifepristone; Pessaries; Pregnancy; Ultrasonography, Prenatal

1992