Page last updated: 2024-08-24

gemcitabine and Osteogenic Sarcoma

gemcitabine has been researched along with Osteogenic Sarcoma in 57 studies

Research

Studies (57)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (1.75)	18.2507
2000's	14 (24.56)	29.6817
2010's	39 (68.42)	24.3611
2020's	3 (5.26)	2.80

Authors

Authors	Studies
Blanco-Prieto, MJ; Couvreur, P; Desmaële, D; Rodríguez-Nogales, C; Sebastián, V	1
Song, JX; Yuan, BS; Yuan, Y; Zhang, MN	1
Huang, Z; Lin, J; Shen, R; Wang, S; Wang, X; Wei, H; Wu, Z	1
Chen, F; Hu, Y; Li, H; Liu, H; Tao, H; Wang, Y	1
Carnero, A; Carranza, A; Cruz, J; Diaz-Beveridge, R; Encinas, V; Garcia Del Muro, X; Gutierrez, A; Hindi, N; Lopez-Pousa, A; Luna, P; Marcilla, D; Martin-Broto, J; Martinez-Trufero, J; Mora, J; Moura, DS; Redondo, A; Sancho, P; Taron, M; Tous, C; Valverde, C; Vaz, MA	1
Li, D; Liu, J; Lu, Y; Wang, S; Wang, Y	1
Caliskan, Y; Dalgic, AD; Gerekci, S; Gulec, EA; Keskin, D; Ozen, C; Tezcaner, A	1
Jian, YK; Li, B; Sun, ZY; Zhu, HY	1
Chang, YJ; Chen, HA; Huang, CY; Huang, MT; Makondi, PT; Wang, JW; Wei, PL	1
Cheng, R; Cui, W; Dai, Y; Liu, H; Ni, Q; Wu, W; Ye, T	1
Gao, J; Gao, W; Ma, J	1
Constantinidou, A; Jones, RL; Loggers, E; Pollack, S; Rodler, E	1
Altiok, S; Bui, MM; Foroutan, P; Gillies, RJ; Kreahling, JM; Letson, D; Martinez, G; Raghavan, M; Razabdouski, T; Reed, D	1
Chitkara, D; Kumar, N	1
Altiok, S; Foroutan, P; Gillies, RJ; Grove, O; Kreahling, JM; Lloyd, MC; Martinez, GV; Morse, DL; Raghavan, M; Reed, D	1
Bar-Sela, G; Miller, RC; Novotny, PJ; Sio, TT; Sohawon, S; Thariat, J; Van Houtte, P; Vu, CC	1
Kim, DH; Lee, JA; Lim, JS; Seo, J; Song, BS; Yoo, JY	1
Gordon, N; O'Farrill, JS	1
Huang, G; Kleinerman, ES; Nishimoto, K; Yang, Y	1
Rodriguez, CO	1
Wang, WM; Wei, MY; Zhuang, YF	1
Wang, W; Wang, Z; Xiao, X	1
Li, QH; Liu, P; Sun, L; Zhang, P; Zhou, DS	1
Cousin, S; Ducoulombier, A; Kotecki, N; Penel, N	1
Kim, DH; Kim, MS; Lee, JA; Lim, JS; Paik, EK; Seo, J; Yoo, JY	1
Gan, ZH; Han, K; Hu, HY; Li, KP; Lin, SC; Liu, Y; Lu, ZG; Min, DL; Tseng, KF; Zhao, RH; Zhou, Y	1
Asaftei, S; Cesari, M; Coccoli, L; Fagioli, F; Ferrari, S; Grignani, G; Jones, RL; Longhi, A; Marchesi, E; Meazza, C; Paioli, A; Palmerini, E; Picci, P; Pollack, SM; Tamburini, A	1
Ahn, HS; Baek, HJ; Cho, WH; Choi, HS; Im, HJ; Jeon, DG; Kang, HJ; Koh, KN; Koo, HH; Kook, H; Lee, JA; Lee, JW; Lim, YJ; Park, BK; Park, HJ; Park, KD; Seo, JJ; Shin, HY; Song, WS; Sung, KW; Yoo, KH; Yoon, HS	1
Kitawaki, J; Kokabu, T; Konishi, E; Mori, T; Tsukasaki, N; Yasukawa, S	1
Chuman, H; Hatano, H; Hiraga, H; Hosaka, M; Iwamoto, Y; Joyama, S; Kaya, M; Kubo, T; Morioka, H; Nagano, A; Nishida, Y; Takahashi, M; Tanaka, K; Toguchida, J; Tsumura, H; Yoshikawa, H	1
Blackwood, E; Cao, Y; Evangelista, M; Klijn, C; Lee, HJ; Pham, V; Settleman, J; Stokoe, D; Wilson, C	1
Gorlick, R; O'Day, K	1
Cruz, CO; de Torres, C; Mora, J; Parareda, A	1
Anderson, PM; Cannan, VA; Crabbs, TA; Gordon, N; Kleinerman, E; Koshkina, N; Rodriguez, CO; Skorupski, KA; Wilson, DW	1
Feng, J; Liu, B; Shi, ZL; Tao, HM; Yan, XB; Zhang, B	1
Gordon, N; Kleinerman, ES	1
Bear, MD; Kulp, SK; London, CA; McMahon, MB; Pennell, ML	1
Grigull, L; Hartmann, C; Linderkamp, C; Reinhardt, D; Sander, A; Schmid, H; Weinel, P; Welte, K	1
Ben-Ami, T; Gosiengfiao, Y; Reichek, J; Walterhouse, D; Woodman, J	1
Lai, J; Li, H; Liang, C; Liu, B; Shen, C; Shi, Z; Tao, HM	1
Benjamin, RS; Chawla, S; Chugh, R; Fox, E; Harmon, D; Helman, LJ; Patel, S; Reinke, D; Schuetze, S; Wathen, JK	1
He, AN; Lin, F; Qi, WX; Shen, Z; Tang, LN; Yao, Y	1
He, A; Huang, Y; Qi, W; Shen, Z; Sun, Y; Yang, Y; Yao, Y; Zhao, H	1
Lim, YL; Tay, EY	1
Bickels, J; Inbar, M; Kollender, Y; Meller, I; Merimsky, O	1
Kleinerman, ES; Koshkina, NV	1
Filipski, E; Focan, C; Kayitalire, L; Lévi, F; Li, XM; Sun, J; Tanaka, K	1
Ando, T; Hamada, Y; Ichikawa, J; Nakao, A; Okamoto, A; Tasaka, K	1
Brodsky, I; Rosenbluth, JZ; Styler, MJ; Zak, D	1
Albritton, K; Anderson, PM; Dubansky, SA; Erlandson, L; Rodriguez, V; Trotz, B; Wiseman, GA	1
Gordon, N; Jia, SF; Khanna, C; Kleinerman, ES; Koshkina, NV; Mendoza, A; Worth, LL	1
Daw, NC; Furman, W; McCarville, MB; Navid, F; Roberts, W; Watkins, A; Willert, JR	1
Inbar, M; Kollender, Y; Meller, I; Merimsky, O	1
Ariad, S; Fenig, E; Flusser, G; Inbar, M; Issakov, J; Kollender, Y; Meller, I; Merimsky, O; Neuman, G; Sapir, D; Weil-Ben-Arush, M	1
Johansson, M; Karlsson, A; Zheng, X	1
Duan Xp, XP; Jia, SF; Kleinerman, ES; Turan, M; Worth, LL	1
Hisada, T; Ito, T; Masuda, S; Mochida, A; Morinari, H; Nakahara, K; Nishi, K; Saito, K; Sasaki, S; Tahara, M; Yakumaru, K	1

Reviews

11 review(s) available for gemcitabine and Osteogenic Sarcoma

Article	Year
The evolution of systemic therapy in sarcoma. Expert review of anticancer therapy, 2013, Volume: 13, Issue:2 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chordoma; Deoxycytidine; Dermatofibrosarcoma; Dioxoles; Docetaxel; Drug Resistance, Neoplasm; Gemcitabine; Hemangiosarcoma; Humans; Osteosarcoma; Proteasome Inhibitors; Receptor, IGF Type 1; Sarcoma; Soft Tissue Neoplasms; Taxoids; Tetrahydroisoquinolines; TOR Serine-Threonine Kinases; Trabectedin	2013
Autophagy in osteosarcoma. Advances in experimental medicine and biology, 2014, Volume: 804 Topics: Animals; Antimetabolites, Antineoplastic; Autophagy; Bone and Bones; Bone Neoplasms; Cell Line, Tumor; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Hydroxychloroquine; Lung; Lung Neoplasms; Mice; Osteosarcoma; Species Specificity	2014
Participation of the Fas/FasL signaling pathway and the lung microenvironment in the development of osteosarcoma lung metastases. Advances in experimental medicine and biology, 2014, Volume: 804 Topics: Animals; Antineoplastic Agents; Benzamides; Bone Neoplasms; Deoxycytidine; Epigenesis, Genetic; Fas Ligand Protein; fas Receptor; Gemcitabine; Humans; Lung Neoplasms; Mice; MicroRNAs; Osteosarcoma; Pyridines; RNA, Long Noncoding; Signal Transduction; Tumor Microenvironment	2014
Using canine osteosarcoma as a model to assess efficacy of novel therapies: can old dogs teach us new tricks? Advances in experimental medicine and biology, 2014, Volume: 804 Topics: Acetylmuramyl-Alanyl-Isoglutamine; Aerosols; Animals; Antineoplastic Agents; Bone Neoplasms; Child; Deoxycytidine; Dog Diseases; Dogs; Gemcitabine; Humans; Interleukin-2; Lung Neoplasms; Molybdenum; Osteosarcoma; Phosphatidylethanolamines; Signal Transduction	2014
Gemcitabine for the treatment of patients with osteosarcoma. Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:17 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Deoxycytidine; Gemcitabine; Humans; Osteosarcoma; Treatment Outcome	2014
The role of chemotherapy for metastatic, relapsed and refractory osteosarcoma. Paediatric drugs, 2014, Volume: 16, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Deoxycytidine; Docetaxel; Etoposide; Gemcitabine; Humans; Ifosfamide; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Taxoids	2014
Gemcitabine-based chemotherapy in sarcomas: A systematic review of published trials. Critical reviews in oncology/hematology, 2016, Volume: 98 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Deoxycytidine; Gemcitabine; Humans; Leiomyosarcoma; Osteosarcoma; Sarcoma	2016
Novel therapeutic agents for osteosarcoma. Expert review of anticancer therapy, 2009, Volume: 9, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Diphosphonates; Docetaxel; Dogs; Drug Delivery Systems; Folic Acid Antagonists; Gemcitabine; Humans; Immunologic Factors; Neoadjuvant Therapy; Neoplasm Proteins; Osteosarcoma; Protein Kinase Inhibitors; Radiopharmaceuticals; Signal Transduction; Survival Rate; Taxoids; Xenograft Model Antitumor Assays; Young Adult	2009
Aerosol therapy for the treatment of osteosarcoma lung metastases: targeting the Fas/FasL pathway and rationale for the use of gemcitabine. Journal of aerosol medicine and pulmonary drug delivery, 2010, Volume: 23, Issue:4 Topics: Aerosols; Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Deoxycytidine; Fas Ligand Protein; fas Receptor; Gemcitabine; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Osteosarcoma	2010
Palliative treatment for advanced or metastatic osteosarcoma. The Israel Medical Association journal : IMAJ, 2004, Volume: 6, Issue:1 Topics: Amputation, Surgical; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Deoxycytidine; Doxorubicin; Gemcitabine; Humans; Ifosfamide; Lung Neoplasms; Neoplasm Recurrence, Local; Osteosarcoma; Palliative Care; Pneumonectomy; Prognosis; Radiotherapy, Adjuvant; Severity of Illness Index; Survival Rate; Treatment Outcome	2004
Combination of gemcitabine and irinotecan for recurrent metastatic osteogenic sarcoma. Clinical advances in hematology & oncology : H&O, 2005, Volume: 3, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Cisplatin; Combined Modality Therapy; Deoxycytidine; Doxorubicin; Etoposide; Femoral Neoplasms; Gemcitabine; Head and Neck Neoplasms; Humans; Ifosfamide; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Palliative Care; Salvage Therapy; Scalp; Skin Neoplasms; Thoracotomy	2005

Trials

6 trial(s) available for gemcitabine and Osteogenic Sarcoma

Article	Year
Gemcitabine plus sirolimus for relapsed and progressing osteosarcoma patients after standard chemotherapy: a multicenter, single-arm phase II trial of Spanish Group for Research on Sarcoma (GEIS). Annals of oncology : official journal of the European Society for Medical Oncology, 2017, Dec-01, Volume: 28, Issue:12 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Deoxycytidine; Disease Progression; Disease-Free Survival; Female; Gemcitabine; Humans; Male; Middle Aged; Osteosarcoma; Recurrence; Sirolimus; Young Adult	2017
Wee1 inhibition by MK-1775 leads to tumor inhibition and enhances efficacy of gemcitabine in human sarcomas. PloS one, 2013, Volume: 8, Issue:3 Topics: Adolescent; Adult; Animals; Antimetabolites, Antineoplastic; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line, Tumor; Child; Child, Preschool; Deoxycytidine; Drug Synergism; Female; Femoral Neoplasms; Gemcitabine; Humans; Male; Mice; Mice, SCID; Middle Aged; Neoplasm Transplantation; Nuclear Proteins; Osteosarcoma; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Pyrimidinones; Transplantation, Heterologous; Xenograft Model Antitumor Assays	2013
Gemcitabine and docetaxel for the treatment of children and adolescents with recurrent or refractory osteosarcoma: Korea Cancer Center Hospital experience. Pediatric blood & cancer, 2014, Volume: 61, Issue:8 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Deoxycytidine; Disease-Free Survival; Docetaxel; Female; Gemcitabine; Humans; Male; Osteosarcoma; Republic of Korea; Retrospective Studies; Survival Rate; Taxoids	2014
Treatment of relapsed/refractory pediatric sarcomas with gemcitabine and docetaxel. Journal of pediatric hematology/oncology, 2009, Volume: 31, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Deoxycytidine; Disease Progression; Docetaxel; Female; Gemcitabine; Humans; Male; Osteosarcoma; Outpatients; Remission Induction; Salvage Therapy; Sarcoma; Sarcoma, Ewing; Sarcoma, Synovial; Survival Analysis; Taxoids; Treatment Outcome	2009
Phase II study of sequential gemcitabine followed by docetaxel for recurrent Ewing sarcoma, osteosarcoma, or unresectable or locally recurrent chondrosarcoma: results of Sarcoma Alliance for Research Through Collaboration Study 003. The oncologist, 2012, Volume: 17, Issue:3 Topics: Adolescent; Adult; Aged; Bone Neoplasms; Chondrosarcoma; Deoxycytidine; Docetaxel; Drug Administration Schedule; Female; Gemcitabine; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Osteosarcoma; Sarcoma, Ewing; Taxoids	2012
Gemcitabine in soft tissue or bone sarcoma resistant to standard chemotherapy: a phase II study. Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:2 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Neoplasms; Chondrosarcoma; Deoxycytidine; Disease Progression; Female; Gemcitabine; Humans; Leiomyosarcoma; Male; Middle Aged; Neoplasm Recurrence, Local; Osteosarcoma; Sarcoma; Soft Tissue Neoplasms; Treatment Outcome	2000

Other Studies

40 other study(ies) available for gemcitabine and Osteogenic Sarcoma

Article	Year
Decoration of Squalenoyl-Gemcitabine Nanoparticles with Squalenyl-Hydroxybisphosphonate for the Treatment of Bone Tumors. ChemMedChem, 2021, 12-14, Volume: 16, Issue:24 Topics: Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Molecular Structure; Nanoparticles; Organophosphonates; Osteosarcoma; Squalene; Structure-Activity Relationship	2021
A multiple drug loaded, functionalized pH-sensitive nanocarrier as therapeutic and epigenetic modulator for osteosarcoma. Scientific reports, 2020, 09-23, Volume: 10, Issue:1 Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Deoxycytidine; Drug Combinations; Epigenesis, Genetic; Epirubicin; Gemcitabine; Hydrogen-Ion Concentration; Male; Nanocapsules; Osteosarcoma; Particle Size; Rats; Rats, Sprague-Dawley	2020
Epidermal growth factor receptor promotes tumor progression and contributes to gemcitabine resistance in osteosarcoma. Acta biochimica et biophysica Sinica, 2021, Mar-02, Volume: 53, Issue:3 Topics: Bone Neoplasms; Cell Line, Tumor; Deoxycytidine; Drug Resistance, Neoplasm; ErbB Receptors; Gemcitabine; Humans; Neoplasm Proteins; Osteosarcoma	2021
Wnt/β-catenin signaling pathway activation reverses gemcitabine resistance by attenuating Beclin1-mediated autophagy in the MG63 human osteosarcoma cell line. Molecular medicine reports, 2017, Volume: 16, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Autophagy; Autophagy-Related Proteins; Beclin-1; Bone Neoplasms; Caspase 3; Caspase 7; Cell Line, Tumor; Cyclin D1; Deoxycytidine; Gemcitabine; Genes, bcl-2; Humans; Lysosomal Membrane Proteins; Osteosarcoma; Wnt Signaling Pathway	2017
Licoricidin enhances gemcitabine-induced cytotoxicity in osteosarcoma cells by suppressing the Akt and NF-κB signal pathways. Chemico-biological interactions, 2018, Jun-25, Volume: 290 Topics: Animals; Antimetabolites, Antineoplastic; Benzopyrans; Bone Neoplasms; Caspase 3; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Osteosarcoma; Proto-Oncogene Proteins c-akt; Signal Transduction; Transplantation, Heterologous	2018
A new therapeutic combination for osteosarcoma: Gemcitabine and Clofazimine co-loaded liposomal formulation. International journal of pharmaceutics, 2019, Feb-25, Volume: 557 Topics: Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Clofazimine; Deoxycytidine; Drug Combinations; Drug Synergism; Gemcitabine; Humans; Liposomes; Osteosarcoma	2019
lncRNAPVT1 targets miR-152 to enhance chemoresistance of osteosarcoma to gemcitabine through activating c-MET/PI3K/AKT pathway. Pathology, research and practice, 2019, Volume: 215, Issue:3 Topics: Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Deoxycytidine; Drug Resistance, Neoplasm; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Osteosarcoma; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; RNA, Long Noncoding; Signal Transduction	2019
Glucose-Regulated Protein 94 Modulates the Response of Osteosarcoma to Chemotherapy. Disease markers, 2019, Volume: 2019 Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Deoxycytidine; Drug Resistance, Neoplasm; Epirubicin; Gemcitabine; Humans; Membrane Glycoproteins; Osteosarcoma; Paclitaxel	2019
Local release of gemcitabine via in situ UV-crosslinked lipid-strengthened hydrogel for inhibiting osteosarcoma. Drug delivery, 2018, Volume: 25, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Carriers; Drug Delivery Systems; Drug Implants; Gelatin; Gemcitabine; Humans; Hydrogels; In Vitro Techniques; Liposomes; Mice; Osteosarcoma; Ultraviolet Rays; Xenograft Model Antitumor Assays	2018
sCLU as prognostic biomarker and therapeutic target in osteosarcoma. Bioengineered, 2019, Volume: 10, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Apolipoproteins; Biomarkers; Cell Line, Tumor; Cell Proliferation; Clusterin; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Lung Neoplasms; Mice; Osteosarcoma; Prognosis; Xenograft Model Antitumor Assays	2019
BSA-PLGA-based core-shell nanoparticles as carrier system for water-soluble drugs. Pharmaceutical research, 2013, Volume: 30, Issue:9 Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Carriers; Gemcitabine; Humans; Lactic Acid; Nanoparticles; Osteosarcoma; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum Albumin, Bovine; Solubility; Water	2013
Diffusion MRI and novel texture analysis in osteosarcoma xenotransplants predicts response to anti-checkpoint therapy. PloS one, 2013, Volume: 8, Issue:12 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cell Cycle Checkpoints; Deoxycytidine; Diffusion Magnetic Resonance Imaging; Female; Gemcitabine; Humans; Mice; Mice, SCID; Middle Aged; Molecular Targeted Therapy; Osteosarcoma; Prognosis; Pyrazoles; Pyrimidines; Pyrimidinones; Treatment Outcome; Xenograft Model Antitumor Assays	2013
Extraskeletal Osteosarcoma: An International Rare Cancer Network Study. American journal of clinical oncology, 2016, Volume: 39, Issue:1 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Cisplatin; Cohort Studies; Deoxycytidine; Disease-Free Survival; Doxorubicin; Etoposide; Female; Gemcitabine; Humans; Ifosfamide; Lower Extremity; Male; Methotrexate; Middle Aged; Mitomycin; Multivariate Analysis; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Staging; Osteosarcoma; Pelvic Neoplasms; Prognosis; Radiotherapy; Rare Diseases; Retroperitoneal Neoplasms; Retrospective Studies; Soft Tissue Neoplasms; Tumor Burden; Young Adult	2016
Gemcitabine and γ-cyclodextrin/docetaxel inclusion complex-loaded liposome for highly effective combinational therapy of osteosarcoma. International journal of pharmaceutics, 2015, Jan-15, Volume: 478, Issue:1 Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Deoxycytidine; Docetaxel; Drug Combinations; Drug Liberation; gamma-Cyclodextrins; Gemcitabine; Humans; Liposomes; Mice, Nude; Nanostructures; Osteosarcoma; Taxoids; Tumor Burden; Xenograft Model Antitumor Assays	2015
Radiotherapy and gemcitabine-docetaxel chemotherapy in children and adolescents with unresectable recurrent or refractory osteosarcoma. Japanese journal of clinical oncology, 2016, Volume: 46, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Deoxycytidine; Disease-Free Survival; Docetaxel; Drug Administration Schedule; Female; Gemcitabine; Humans; Kaplan-Meier Estimate; Male; Osteosarcoma; Radiotherapy Dosage; Radiotherapy, Adjuvant; Republic of Korea; Retrospective Studies; Taxoids; Treatment Outcome	2016
Sirolimus induces apoptosis and reverses multidrug resistance in human osteosarcoma cells in vitro via increasing microRNA-34b expression. Acta pharmacologica Sinica, 2016, Volume: 37, Issue:4 Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Deoxycytidine; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; HEK293 Cells; Humans; Methotrexate; MicroRNAs; Osteosarcoma; Sirolimus	2016
Gemcitabine and docetaxel in relapsed and unresectable high-grade osteosarcoma and spindle cell sarcoma of bone. BMC cancer, 2016, Apr-20, Volume: 16 Topics: Adolescent; Adult; Aged; Child; Deoxycytidine; Disease-Free Survival; Docetaxel; Female; Gemcitabine; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Grading; Neoplasm Recurrence, Local; Osteosarcoma; Recurrence; Sarcoma; Taxoids; Treatment Outcome	2016
Higher Gemcitabine Dose Was Associated With Better Outcome of Osteosarcoma Patients Receiving Gemcitabine-Docetaxel Chemotherapy. Pediatric blood & cancer, 2016, Volume: 63, Issue:9 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Deoxycytidine; Docetaxel; Female; Gemcitabine; Humans; Male; Osteosarcoma; Retrospective Studies; Taxoids	2016
Primary osteosarcoma of the uterine corpus: A case report. The journal of obstetrics and gynaecology research, 2016, Volume: 42, Issue:11 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Deoxycytidine; Docetaxel; Female; Gemcitabine; Humans; Hysterectomy; Lung Neoplasms; Middle Aged; Osteosarcoma; Taxoids; Treatment Outcome; Uterine Neoplasms	2016
Feasibility and efficacy of gemcitabine and docetaxel combination chemotherapy for bone and soft tissue sarcomas: multi-institutional retrospective analysis of 134 patients. World journal of surgical oncology, 2016, Dec-08, Volume: 14, Issue:1 Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Deoxycytidine; Disease-Free Survival; Docetaxel; Feasibility Studies; Gemcitabine; Humans; Japan; Middle Aged; Neutropenia; Osteosarcoma; Pneumonia; Retrospective Studies; Sarcoma; Taxoids; Treatment Outcome; Tubulin Modulators; Young Adult	2016
Ras-MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells. Molecular cancer therapeutics, 2017, Volume: 16, Issue:4 Topics: Animals; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Checkpoint Kinase 1; Deoxycytidine; DNA Damage; Female; Gemcitabine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 3-Ring; Humans; MAP Kinase Signaling System; Mice; Osteosarcoma; Ovarian Neoplasms; Piperidines; Proto-Oncogene Proteins p21(ras); Xenograft Model Antitumor Assays	2017
Aerosol gemcitabine: preclinical safety and in vivo antitumor activity in osteosarcoma-bearing dogs. Journal of aerosol medicine and pulmonary drug delivery, 2010, Volume: 23, Issue:4 Topics: Aerosols; Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Deoxycytidine; Dogs; Fas Ligand Protein; fas Receptor; Gemcitabine; Lung Neoplasms; Osteosarcoma	2010
Enhanced anticancer effect of gemcitabine by genistein in osteosarcoma: the role of Akt and nuclear factor-kappaB. Anti-cancer drugs, 2010, Volume: 21, Issue:3 Topics: Antimetabolites, Antineoplastic; Antineoplastic Protocols; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Synergism; Gemcitabine; Genistein; Humans; NF-kappa B; Osteosarcoma; Proto-Oncogene Proteins c-akt	2010
Biological activity of gemcitabine against canine osteosarcoma cell lines in vitro. American journal of veterinary research, 2010, Volume: 71, Issue:7 Topics: Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Carboplatin; Cell Line, Tumor; Cell Survival; Deoxycytidine; Diphosphonates; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gemcitabine; Osteosarcoma; Pamidronate	2010
Oxaliplatin, irinotecan, and gemcitabine: a novel combination in the therapy of progressed, relapsed, or refractory tumors in children. Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:5 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Neuroendocrine; Central Nervous System Neoplasms; Cerebellar Neoplasms; Child; Child, Preschool; Deoxycytidine; Drug Resistance, Neoplasm; Female; Gemcitabine; Humans; Irinotecan; Lung Neoplasms; Male; Medulloblastoma; Neoplasm Recurrence, Local; Neuroblastoma; Organoplatinum Compounds; Osteosarcoma; Oxaliplatin; Retrospective Studies; Treatment Outcome	2011
Gemcitabine with or without docetaxel and resection for recurrent osteosarcoma: the experience at Children's Memorial Hospital. Journal of pediatric hematology/oncology, 2012, Volume: 34, Issue:2 Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Child; Combined Modality Therapy; Deoxycytidine; Docetaxel; Female; Gemcitabine; Humans; Male; Neoplasm Recurrence, Local; Neurosurgical Procedures; Osteosarcoma; Retrospective Studies; Taxoids; Treatment Outcome	2012
Genistein potentiates the anti-cancer effects of gemcitabine in human osteosarcoma via the downregulation of Akt and nuclear factor-κB pathway. Anti-cancer agents in medicinal chemistry, 2012, Volume: 12, Issue:5 Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Deoxycytidine; Down-Regulation; Drug Synergism; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Genistein; Humans; Mice; Mice, Inbred BALB C; NF-kappa B; Osteosarcoma; Proto-Oncogene Proteins c-akt; Signal Transduction	2012
Efficacy and safety of gemcitabine-docetaxel combination therapy for recurrent or refractory high-grade osteosarcoma in China: a retrospective study of 18 patients. Japanese journal of clinical oncology, 2012, Volume: 42, Issue:5 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; China; Deoxycytidine; Disease Progression; Docetaxel; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Gemcitabine; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Recurrence, Local; Osteosarcoma; Retrospective Studies; Salvage Therapy; Taxoids; Treatment Outcome	2012
Comparison of pirarubicin-based versus gemcitabine-docetaxel chemotherapy for relapsed and refractory osteosarcoma: a single institution experience. International journal of clinical oncology, 2013, Volume: 18, Issue:3 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Deoxycytidine; Disease-Free Survival; Docetaxel; Doxorubicin; Drug-Related Side Effects and Adverse Reactions; Female; Gemcitabine; Humans; Ifosfamide; Kaplan-Meier Estimate; Male; Middle Aged; Osteosarcoma; Prospective Studies; Taxoids	2013
Toxic erythema of chemotherapy with periorbital and perioral involvement. Singapore medical journal, 2012, Volume: 53, Issue:11 Topics: Antineoplastic Agents; Axilla; Bone Neoplasms; Child; Deoxycytidine; Docetaxel; Erythema; Female; Femur; Gemcitabine; Humans; Hyperpigmentation; Lung Neoplasms; Mouth; Orbit; Osteosarcoma; Taxoids; Treatment Outcome	2012
Aerosol gemcitabine inhibits the growth of primary osteosarcoma and osteosarcoma lung metastases. International journal of cancer, 2005, Sep-01, Volume: 116, Issue:3 Topics: Aerosols; Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Deoxycytidine; Disease Models, Animal; fas Receptor; Gemcitabine; Lung Neoplasms; Mice; Mice, Nude; Osteosarcoma; Tumor Cells, Cultured	2005
Preclinical relevance of dosing time for the therapeutic index of gemcitabine-cisplatin. British journal of cancer, 2005, May-09, Volume: 92, Issue:9 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Circadian Rhythm; Cisplatin; Deoxycytidine; Drug Administration Schedule; Female; Gemcitabine; Male; Mice; Mice, Inbred C57BL; Osteosarcoma	2005
Gemcitabine inhibits viability, growth, and metastasis of osteosarcoma cell lines. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2005, Volume: 23, Issue:4 Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Bone Neoplasms; Cell Division; Cell Line, Tumor; Cell Survival; Deoxycytidine; DNA; Fibroblasts; Gemcitabine; Humans; Lung Neoplasms; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Osteosarcoma	2005
Gemcitabine radiosensitization after high-dose samarium for osteoblastic osteosarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 1 Topics: Adolescent; Adult; Alkaline Phosphatase; Analgesics, Non-Narcotic; Antigens, CD34; Bone and Bones; Bone Neoplasms; Combined Modality Therapy; Deoxycytidine; Gemcitabine; Humans; Image Processing, Computer-Assisted; Neoplasm Metastasis; Organometallic Compounds; Organophosphorus Compounds; Osteosarcoma; Pain; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Remission Induction; Samarium; Sarcoma; Stem Cells; Time Factors	2005
Corruption of the Fas pathway delays the pulmonary clearance of murine osteosarcoma cells, enhances their metastatic potential, and reduces the effect of aerosol gemcitabine. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Aug-01, Volume: 13, Issue:15 Pt 1 Topics: Aerosols; Animals; Apoptosis; Blotting, Western; Bone Neoplasms; Deoxycytidine; fas Receptor; Flow Cytometry; Gemcitabine; Lung Neoplasms; Mice; Mice, Inbred BALB C; Osteosarcoma; RNA, Messenger; Survival Rate; Tumor Cells, Cultured; Up-Regulation	2007
Combination of gemcitabine and docetaxel in the treatment of children and young adults with refractory bone sarcoma. Cancer, 2008, Jul-15, Volume: 113, Issue:2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Deoxycytidine; Docetaxel; Dose-Response Relationship, Drug; Female; Gemcitabine; Humans; Male; Osteosarcoma; Taxoids; Tomography, X-Ray Computed; Treatment Outcome	2008
Palliative effect of gemcitabine in osteosarcoma resistant to standard chemotherapy. European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:8 Topics: Adult; Antimetabolites, Antineoplastic; Carcinoma, Papillary; Deoxycytidine; Drug Resistance, Neoplasm; Female; Gemcitabine; Humans; Osteosarcoma; Palliative Care; Thyroid Neoplasms	1998
Retroviral transduction of cancer cell lines with the gene encoding Drosophila melanogaster multisubstrate deoxyribonucleoside kinase. The Journal of biological chemistry, 2000, Dec-15, Volume: 275, Issue:50 Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Catalysis; Cell Division; Cell Nucleus; Cladribine; Cytarabine; Deoxycytidine; Drosophila melanogaster; Gemcitabine; Humans; Inhibitory Concentration 50; Kinetics; Osteosarcoma; Pancreatic Neoplasms; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Promoter Regions, Genetic; Retroviridae; Substrate Specificity; Thymidine; Thymidine Kinase; Transduction, Genetic; Tumor Cells, Cultured	2000
Eradication of osteosarcoma lung metastasis using intranasal gemcitabine. Anti-cancer drugs, 2002, Volume: 13, Issue:2 Topics: Administration, Intranasal; Animals; Antimetabolites, Antineoplastic; Cell Cycle; Cell Survival; Deoxycytidine; Gemcitabine; Humans; Injections, Intraperitoneal; Lung Neoplasms; Male; Mice; Mice, Nude; Osteosarcoma; Tumor Cells, Cultured	2002
[An autopsy case of pulmonary and central nervous system metastatic osteosarcoma treated with thirty-six courses of chemotherapy over four years]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2002, Volume: 40, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Carboplatin; Cisplatin; Dacarbazine; Deoxycytidine; Docetaxel; Drug Administration Schedule; Etoposide; Gemcitabine; Humans; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Paclitaxel; Spinal Cord Neoplasms; Survivors; Taxoids; Vincristine; Vindesine	2002