Page last updated: 2024-08-24

gemcitabine and Experimental Neoplasms

gemcitabine has been researched along with Experimental Neoplasms in 82 studies

Research

Studies (82)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (7.32)	18.2507
2000's	25 (30.49)	29.6817
2010's	39 (47.56)	24.3611
2020's	12 (14.63)	2.80

Authors

Authors	Studies
Iovanna, JL; Liu, Y; Peng, L; Qu, F; Rocchi, P; Wan, J; Wang, M; Xia, Y	1
Bouska, J; Djuric, SW; Giranda, VL; Johnson, EF; Klinghofer, V; Lasko, LM; Luo, Y; Mitten, MJ; Penning, TD; Shoemaker, AR; Stewart, KD; Vasudevan, A; Xia, Z; Zhang, Q	1
Chen, P; Xu, C; Yang, Y; Zhang, B; Zhang, H; Zhao, L; Zhou, J	1
Du, W; Hu, X; Jin, T; Kan, W; Li, J; Li, K; Liu, T; Wang, C; Wang, P; Wu, Z; Xu, L; Zhang, R; Zhou, Y	1
He, H; Jiang, S; Ling, G; Peng, F; Qin, L; Yang, D; Zhang, F; Zhang, P	1
Ding, C; Hu, X; Tan, X; Wu, C; Yan, J; Zhou, M	1
Lin, W; Lu, B; Shi, L; Yu, J; Zhao, Y	1
Abou Ali, E; Batteux, F; Bordacahar, B; Camus, M; Chouzenoux, S; Jeljeli, M; Lafon, C; Leenhardt, R; Mestas, JL; Nicco, C; Prat, F	1
Ding, X; Huang, W; Jiang, C; Li, F; Sun, T; Wang, Q; Wang, Z; Wu, Z; Zhu, X	1
Foroughi, J; Kim, SC; Shim, IK; Spinks, GM; Talebian, S; Vine, KL	1
Chen, F; Gou, S; Wang, X	2
Capone, A; Capurso, G; de Latouliere, L; Di Agostino, S; Manni, I; Montori, A; Naro, C; Panzeri, V; Piaggio, G; Pilozzi, E; Sacconi, A; Sette, C	1
Hu, X; Li, P; Liu, D; Wang, Y; Wei, X; Wu, J; Zhou, H	1
Chang, M; Hang, T; Hu, Z; Liu, Y; Ning, M; Song, M; Wu, W; Xu, X	1
Gou, S; Liao, Z; Xu, Z; Zhang, B	1
Fujimoto, K; Hori, S; Miyake, M; Morizawa, Y; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y	1
Danishmalik, SN; Sin, JI	1
Avraham, R; Barshack, I; Barzily-Rokni, M; Bhatia, SN; Brandis, A; Bu, J; Chatman, K; Cooper, ZA; Danino, T; Ferrone, CR; Flaherty, KT; Fleming, J; Frederick, DT; Fuks, G; Garrett, WS; Gavert, N; Geller, LT; Gevers, D; Golan, T; Golub, TR; Gopalakrishnan, V; Gurbatri, C; Hurd, MW; Huttenhower, C; Johnston, SE; Jonas, OH; Katz, M; Kim, M; Ligorio, M; Livny, J; Maitra, A; Mandinova, A; Michaud, M; Mosher, CM; Nejman, D; Reuben, A; Sandbank, J; Shee, K; Shental, N; Skalak, M; Smith, DA; Straussman, R; Thaiss, CA; Thayer, SP; Trauger, SA; Wargo, JA; Zwang, Y	1
Hou, J; Jin, W; Yang, Q; Yi, W; Yoo, S; Zhang, P	1
Huang, C; Kwon, GS; Poellmann, M; Tam, YT	1
Baloğlu, E; Çalışkan, Ç; Erzurumlu, Y; Karavana, SY; Özdemir, Dİ; Şen, S; Şenyiğit, ZA; Sevin, G	1
Chen, X; Deng, M; Gu, J; Shen, N; Song, W; Tang, Z; Yang, C; Yin, L; Yu, H; Zhang, D	1
Akhtar, S; David, D; Geamanu, A; Goja, A; Gupta, SV; Razalli, NH; Saadat, N; Shen, Y	1
Anderson, GJ; Du, C; Han, X; Lang, J; Min, H; Nie, G; Qi, Y; Qin, H; Shi, Q; Tian, X; Wang, Y; Yang, Y; Zhang, Y; Zhang, Z; Zhao, X; Zhao, Y	1
Guo, Z; He, S; Hu, Z; Jiang, K; Lin, C; Su, H; Yuan, G; Zeng, Y; Zhong, F	1
Chen, J; Hu, P; Wu, G; Zhou, H	1
Arteta, B; Benedicto, A; Hernandez-Unzueta, I; Herrero, A; Márquez, J; Olaso, E; Romayor, I; Sanz, E	1
Fu, Z; Han, B; Han, H; He, Q; Tang, K; Wang, X; Xu, J; Yin, H; Zhang, X	1
Awasthi, N; Hinz, S; Schwarz, AM; Schwarz, MA; Schwarz, RE; Wang, C; Williams, NS; Zhang, C	1
Del Bene, F; Germani, M; Magni, P; Terranova, N	1
Dito, G; Girit, E; Humphrey, R; Hunt, JT; Jure-Kunkel, M; Lee, F; Masters, G	1
Aleksandrova, LN; Bezborodova, OA; Iakubovskaia, RI; Kovalenko, AL; Nemtsova, ER; Venediktova, IuB	1
Blackwood, E; Del Nagro, C; Evangelista, M; Jackson, PK; Kowanetz, K; Malek, S; O'Brien, T; Ramiscal, J; Xiao, Y	1
Gao, RJ; Li, L; Li, Y; Liu, XJ; Qin, Y; Shao, RG; Zhen, YS	1
Fang, Z; Hong, S; Hong, SS; Jung, KH; Lee, H; Son, MK; Yan, HH	1
Choi, BI; Han, JK; Kim, H; Kim, JH; Kim, YJ; Lee, JY	1
Hirano, S; Kuroda, A; Kuwatani, T; Kyogoku, N; Maki, T; Miyauchi, K; Shichinohe, T; Takeuchi, S; Tsuchikawa, T; Wada, M; Yamamura, Y	1
Cisneros, BT; Corr, SJ; Curley, SA; Liu, H; Raoof, M; Wilson, LJ; Zhu, C	1
Asano, E; Funasaka, K; Goto, H; Hamaguchi, M; Hirooka, Y; Hyodo, T; Miyahara, R; Senga, T; Wong, M	1
Awasthi, N; Brekken, RA; Hinz, S; Schwarz, MA; Schwarz, RE	1
Dosch, JS; Rehemtulla, A; Sebolt-Leopold, JS; Shettigar, A; Ziemke, EK	1
Li, SD; May, JP; Roy, A; Undzys, E	1
Baldwin, GS; Beutler, JA; He, H; Huynh, N; Nikfarjam, M; Yeo, D	1
Fang, W; Tian, Y; Xue, C; Zhan, J; Zhang, J; Zhang, L; Zhao, Y	1
Bains, A; Gong, Q; Gu, Z; Guys, N; Hu, J; Li, J; Li, X; Luo, K; Pan, D; Zhang, C; Zhu, H	1
Eley, HL; McDonald, PS; Russell, ST; Tisdale, MJ	1
De Wit, PE; Folkerts, G; Grootenboers, MJ; Hendriks, JM; Pasterkamp, G; Schramel, FM; van Boven, WJ; van Putte, BP; van Schil, PE	1
Arias, JL; Couvreur, P; Reddy, LH	1
Bieblová, J; Bubeník, J; Indrová, M; Mikyšková, R; Reiniš, M; Símová, J	1
Chenevert, TL; Galbán, CJ; Galbán, S; Heist, KA; Holland, EC; Johnson, TD; Lawrence, TS; Lemasson, B; Leopold, JS; Li, F; Mikkelsen, T; Rehemtulla, A; Ross, BD; Williams, TM	1
Gilbert, KS; Scoggins, JW; Stackhouse, MA; Waud, WR	1
Hirooka, S; Kim, S; Kwon, AH; Matsui, Y; Satoi, S; Toyokawa, H; Yamaki, S; Yamamoto, T; Yamao, J; Yanagimoto, H	1
Bayry, J; Bazhin, AV; Karakhanova, S; Link, J; Shevchenko, I; Soltek, S; Umansky, V; Werner, J	1
Baker, CH; Bucana, CD; Fidler, IJ; Kedar, D; McCarty, MF; Tsan, R; Weber, KL	1
Mornex, F	1
Alvarez, E; Boven, E; Braakhuis, BJ; Kroep, JR; Loves, WJ; Peters, GJ; Pinedo, HM; Talianidis, I; van der Wilt, CL; van Groeningen, CJ	1
Inciūra, A; Juozaityte, E	1
Baker, CH; Bucana, CD; Evans, DB; Fidler, IJ; Hwang, R; Killion, JJ; Pisters, PW; Solorzano, CC	1
Lake, RA; Nowak, AK; Robinson, BW	1
Cardillo, TM; Gold, DV; Modrak, D; Schutsky, K	1
Cardillo, TM; Gold, DV; Modrak, DE; Schutsky, K	1
Alcouffe, C; Boutonnat, J; Clément-Lacroix, J; Mousseau, M; Ronot, X	1
Chen, DT; Desmond, RA; Hemminki, A; Kanerva, A; Kangasniemi, L; Raki, M; Ranki, T; Ristimaki, A; Sarkioja, M	1
Ding, ZY; Hu, B; Kan, B; Li, Q; Liu, JY; Luo, Y; Mao, YQ; Niu, T; Su, JM; Tian, L; Wei, YQ; Wen, YJ; Wu, Y; Xie, XJ; Yang, L	1
Büchler, MW; Büchler, P; Eibl, G; Friess, H; Hines, OJ; Isacoff, WH; Reber, HA; Roth, MA	1
Albelda, SM; Jassar, AS; Kaiser, LR; Kapoor, V; Suzuki, E	1
Abbruzzese, JL; Coombes, KR; Fidler, IJ; Hamilton, SR; Hawke, D; Kobayashi, R; Koomen, J; Li, D; Shih, LC; Yokoi, K	1
Boisdron-Celle, M; Diot, P; Fournier, J; Gagnadoux, F; Hureaux, J; Le Pape, A; Leblond, V; Lemarié, E; Majoral, C; Montharu, J; Racineux, JL; Urban, T; Vecellio, L	1
Buscail, L; Cordelier, P; Drocourt, D; Ghénassia, L; Lulka, H; Pradayrol, L; Pyronnet, S; Souque, A; Tiraby, G; Vernejoul, F	1
Bowerman, NA; Fu, YX; Kranz, DM; Rowley, DA; Salama, JK; Schietinger, A; Schmidt, H; Schreiber, H; Spiotto, MT; Weichselbaum, RR; Yu, P; Zhang, B	1
Ansiaux, R; Beghein, N; Cron, GO; Feron, O; Gallez, B; Martinive, P	1
Clarenbach, R; Märten, A; Nagaraj, S; Sauerbruch, T; Schmidt, T; Schmidt-Wolf, IG; Schmitz, V; Tiemann, K; Ziske, C	1
Hansen, HH; Kristjansen, PE; Lund, B	1
Bamberger, U; Boven, E; Feller, N; Jansen, WJ; Pinedo, HM; van der Wilt, CL	1
Hui, YF; Reitz, J	1
Ang, KK; Elshaikh, M; Fujii, T; Hittelman, W; Hunter, N; Mason, K; Milas, L; Plunkett, W	1
Czerniak, PM; Devenny, JJ; Gravallese, EM; Kerr, JS; Longtine, J; Slee, AM; Wexler, EJ; Wong, MK	1
Blackstock, AW; Case, LD; Hess, SM; Lightfoot, H; Mitchell, BS; Mukherji, SK; Swarts, SG; Tepper, JE	1
Hedley, DW; Ng, SS; Nicklee, T; Tsao, MS	1
Degen, D; Grindey, GB; Hanauske, AR; Hilsenbeck, SG; Marshall, MH; Von Hoff, DD	1
Boder, GB; Grindey, GB; Hertel, LW; Kroin, JS; Poore, GA; Rinzel, SM; Todd, GC	1

Reviews

3 review(s) available for gemcitabine and Experimental Neoplasms

Article	Year
[Combined gemcitabine and radiotherapy]. Bulletin du cancer, 2002, Volume: 89 Spec No Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Drug Administration Schedule; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Lung Neoplasms; Maximum Tolerated Dose; Multicenter Studies as Topic; Neoplasms; Neoplasms, Experimental; Otorhinolaryngologic Neoplasms; Pancreatic Neoplasms; Prodrugs; Radiation Injuries; Radiation-Sensitizing Agents; Radiotherapy; Tumor Cells, Cultured	2002
Clinical and preclinical activity of 2',2'-difluorodeoxycytidine (gemcitabine). Cancer treatment reviews, 1993, Volume: 19, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Deoxycytidine; Drug Evaluation; Drug Evaluation, Preclinical; Gemcitabine; Humans; Neoplasms; Neoplasms, Experimental	1993
Gemcitabine: a cytidine analogue active against solid tumors. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1997, Jan-15, Volume: 54, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Deoxycytidine; Gemcitabine; Humans; Neoplasms; Neoplasms, Experimental	1997

Other Studies

79 other study(ies) available for gemcitabine and Experimental Neoplasms

Article	Year
Novel triazole ribonucleoside down-regulates heat shock protein 27 and induces potent anticancer activity on drug-resistant pancreatic cancer. Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19 Topics: Animals; Apoptosis; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; HSP27 Heat-Shock Proteins; Humans; Mice; Neoplasms, Experimental; Pancreatic Neoplasms; Ribonucleosides; Transplantation, Heterologous; Treatment Outcome; Triazoles	2009
Hit to Lead optimization of a novel class of squarate-containing polo-like kinases inhibitors. Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24 Topics: Animals; Antineoplastic Agents; Cell Cycle Proteins; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; High-Throughput Screening Assays; Humans; Mice; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Structure-Activity Relationship	2012
Design, synthesis and biological evaluation of imidazolopyridone derivatives as novel BRD4 inhibitors. Bioorganic & medicinal chemistry, 2021, 01-01, Volume: 29 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Imidazoles; Male; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Molecular Structure; Neoplasms, Experimental; Pyridones; Structure-Activity Relationship; Transcription Factors	2021
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile. Journal of medicinal chemistry, 2021, 10-28, Volume: 64, Issue:20 Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Cell Line; Cell Proliferation; Checkpoint Kinase 1; Dose-Response Relationship, Drug; Drug Development; Humans; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Protein Kinase Inhibitors; Structure-Activity Relationship	2021
Black phosphorus nanosheets and gemcitabine encapsulated thermo-sensitive hydrogel for synergistic photothermal-chemotherapy. Journal of colloid and interface science, 2019, Nov-15, Volume: 556 Topics: Animals; Cell Line, Tumor; Deoxycytidine; Female; Gemcitabine; Hydrogels; Hyperthermia, Induced; Mice; Mice, Inbred BALB C; Nanocapsules; Neoplasms, Experimental; Phosphorus; Phototherapy	2019
Tumor Microenvironment following Gemcitabine Treatment Favors Differentiation of Immunosuppressive Ly6C Journal of immunology (Baltimore, Md. : 1950), 2020, 01-01, Volume: 204, Issue:1 Topics: Animals; Antigens, Ly; Antimetabolites, Antineoplastic; Apoptosis; Cell Differentiation; Cell Proliferation; Deoxycytidine; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Immunosuppressive Agents; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myeloid Cells; Neoplasms, Experimental; Tumor Cells, Cultured; Tumor Microenvironment	2020
UCP2 promotes proliferation and chemoresistance through regulating the NF-κB/β-catenin axis and mitochondrial ROS in gallbladder cancer. Biochemical pharmacology, 2020, Volume: 172 Topics: Animals; Antineoplastic Agents; beta Catenin; Cell Line, Tumor; Cisplatin; Deoxycytidine; Drug Resistance, Neoplasm; Gallbladder Neoplasms; Gemcitabine; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Iridoids; Male; Mice; Mice, Nude; Mitochondria; Neoplasms, Experimental; NF-kappa B; Reactive Oxygen Species; Uncoupling Protein 2; Up-Regulation	2020
Ultrasound-induced Cavitation enhances the efficacy of Chemotherapy in a 3D Model of Pancreatic Ductal Adenocarcinoma with its microenvironment. Scientific reports, 2019, 12-12, Volume: 9, Issue:1 Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deoxycytidine; Gemcitabine; Mice; Mice, Transgenic; Neoplasms, Experimental; Pancreatic Neoplasms; Spheroids, Cellular; Tumor Microenvironment; Ultrasonic Therapy	2019
Theranostic nanoparticles enabling the release of phosphorylated gemcitabine for advanced pancreatic cancer therapy. Journal of materials chemistry. B, 2020, 03-25, Volume: 8, Issue:12 Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Proliferation; Deoxycytidine; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Mice; Mice, Nude; Molecular Structure; Nanoparticles; Neoplasms, Experimental; Optical Imaging; Pancreatic Neoplasms; Particle Size; Photothermal Therapy; Surface Properties; Theranostic Nanomedicine; Tumor Cells, Cultured	2020
Coaxial mussel-inspired biofibers: making of a robust and efficacious depot for cancer drug delivery. Journal of materials chemistry. B, 2020, 06-21, Volume: 8, Issue:23 Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Cell Proliferation; Cell Survival; Deoxycytidine; Doxorubicin; Drug Delivery Systems; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Hydrogels; Male; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Optical Imaging; Particle Size; Proteins; Surface Properties; Tumor Cells, Cultured	2020
Combination of DN604 with gemcitabine led to cell apoptosis and cell motility inhibition via p38 MAPK signaling pathway in NSCLC. Bioorganic chemistry, 2020, Volume: 104 Topics: Animals; Antineoplastic Agents; Apoptosis; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Lung Neoplasms; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Signal Transduction; Structure-Activity Relationship; Tumor Cells, Cultured	2020
The RNA-binding protein MEX3A is a prognostic factor and regulator of resistance to gemcitabine in pancreatic ductal adenocarcinoma. Molecular oncology, 2021, Volume: 15, Issue:2 Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Mice; Mice, Knockout; Neoplasm Proteins; Neoplasms, Experimental; Pancreatic Neoplasms; Phosphoproteins; Prognosis; RNA-Binding Proteins	2021
Anti-tumor effects and cell motility inhibition of the DN604-gemcitabine combined treatment in human bladder cancer models. Bioorganic & medicinal chemistry, 2021, 01-01, Volume: 29 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carboplatin; Cell Movement; Cell Proliferation; Deoxycytidine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Tumor Cells, Cultured; Urinary Bladder Neoplasms	2021
Engineering of gemcitabine coated nano-graphene oxide sheets for efficient near-infrared radiation mediated in vivo lung cancer photothermal therapy. Journal of photochemistry and photobiology. B, Biology, 2021, Volume: 216 Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Deoxycytidine; Female; Gemcitabine; Graphite; Humans; Infrared Rays; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Photothermal Therapy	2021
Danggui Buxue Decoction enhances the anticancer activity of gemcitabine and alleviates gemcitabine-induced myelosuppression. Journal of ethnopharmacology, 2021, Jun-12, Volume: 273 Topics: A549 Cells; Animals; Antineoplastic Agents; Bone Marrow; Cytokines; Deoxycytidine; Drug Synergism; Drugs, Chinese Herbal; Gemcitabine; Gene Expression Regulation; Humans; Mice; Mice, Nude; Neoplasms, Experimental	2021
A gemcitabine-based conjugate with enhanced antitumor efficacy by suppressing HIF-1α expression under hypoxia. Bioorganic & medicinal chemistry, 2021, 07-01, Volume: 41 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Deoxycytidine; Female; Gemcitabine; Hepatocytes; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Oxygen	2021
Topical and systemic immunoreaction triggered by intravesical chemotherapy in an N-butyl-N-(4-hydroxybutyl) nitorosamine induced bladder cancer mouse model. PloS one, 2017, Volume: 12, Issue:4 Topics: Adjuvants, Immunologic; Administration, Intravesical; Animals; Antineoplastic Combined Chemotherapy Protocols; Butylhydroxybutylnitrosamine; Cytokines; Deoxycytidine; Doxorubicin; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice; Mitomycin; Neoplasms, Experimental; Treatment Outcome; Urinary Bladder Neoplasms	2017
Therapeutic Tumor Control of HER2 DNA Vaccines Is Achieved by an Alteration of Tumor Cells and Tumor Microenvironment by Gemcitabine and Anti-Gr-1 Ab Treatment in a HER2-Expressing Tumor Model. DNA and cell biology, 2017, Volume: 36, Issue:9 Topics: Animals; Antibodies; B7-H1 Antigen; Cancer Vaccines; Deoxycytidine; Female; Gemcitabine; Mice, Inbred BALB C; Neoplasms, Experimental; Receptor, ErbB-2; Receptors, Chemokine; T-Lymphocytes, Cytotoxic; Tumor Microenvironment; Vaccines, DNA	2017
Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine. Science (New York, N.Y.), 2017, 09-15, Volume: 357, Issue:6356 Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Pancreatic Ductal; Colonic Neoplasms; Deoxycytidine; Drug Resistance, Neoplasm; Gammaproteobacteria; Gemcitabine; Humans; Male; Mice; Mice, Inbred BALB C; Mycoplasma hyorhinis; Neoplasms, Experimental; Pancreatic Neoplasms	2017
A carbon nanotube-gemcitabine-lentinan three-component composite for chemo-photothermal synergistic therapy of cancer. International journal of nanomedicine, 2018, Volume: 13 Topics: Animals; Antimetabolites, Antineoplastic; Deoxycytidine; Drug Delivery Systems; Female; Gemcitabine; Humans; Laser Therapy; Lasers; Lentinan; MCF-7 Cells; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Nanotubes, Carbon; Neoplasms, Experimental; Phototherapy; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thermogravimetry; Xenograft Model Antitumor Assays	2018
Stereocomplex Prodrugs of Oligo(lactic acid) ACS nano, 2018, 07-24, Volume: 12, Issue:7 Topics: A549 Cells; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytidine; Drug Screening Assays, Antitumor; Female; Gemcitabine; Humans; Lactates; Lactic Acid; Mice; Mice, Nude; Micelles; Molecular Structure; Neoplasms, Experimental; Polyethylene Glycols; Prodrugs; Stereoisomerism	2018
Gemcitabine hydrochloride microspheres used for intravesical treatment of superficial bladder cancer: a comprehensive in vitro/ex vivo/in vivo evaluation. Drug design, development and therapy, 2018, Volume: 12 Topics: Administration, Intravesical; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Deoxycytidine; Drug Compounding; Gemcitabine; Humans; In Vitro Techniques; Microscopy, Electron, Scanning; Microspheres; Neoplasms, Experimental; Particle Size; Rats; Rats, Sprague-Dawley; Rheology; Urinary Bladder Neoplasms; Viscosity	2018
Poly (l-glutamic acid)-g-methoxy poly (ethylene glycol)-gemcitabine conjugate improves the anticancer efficacy of gemcitabine. International journal of pharmaceutics, 2018, Oct-25, Volume: 550, Issue:1-2 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Deoxycytidine; Female; Gemcitabine; Humans; Male; Mice, Inbred BALB C; Neoplasms, Experimental; Polyethylene Glycols; Polyglutamic Acid; Tissue Distribution	2018
Dietary Garcinol Arrests Pancreatic Cancer in p53 and K-ras Conditional Mutant Mouse Model. Nutrition and cancer, 2018, Volume: 70, Issue:7 Topics: Animals; Antineoplastic Agents, Phytogenic; Deoxycytidine; Dietary Supplements; Gemcitabine; Genes, p53; Genes, ras; Humans; Magnetic Resonance Imaging; Male; Mice, Transgenic; Neoplasms, Experimental; Pancreatic Neoplasms; S100 Calcium Binding Protein beta Subunit; Smad4 Protein; Survival Rate; Terpenes	2018
Epidermal Growth Factor Receptor-Targeting Peptide Nanoparticles Simultaneously Deliver Gemcitabine and Olaparib To Treat Pancreatic Cancer with Breast Cancer 2 ( BRCA2) Mutation. ACS nano, 2018, 11-27, Volume: 12, Issue:11 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; BRCA2 Protein; Deoxycytidine; Drug Delivery Systems; ErbB Receptors; Female; Gemcitabine; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Nanoparticles; Neoplasms, Experimental; Pancreatic Neoplasms; Peptides; Phthalazines; Piperazines	2018
HIF1α-siRNA and gemcitabine combination-based GE-11 peptide antibody-targeted nanomedicine for enhanced therapeutic efficacy in pancreatic cancers. Journal of drug targeting, 2019, Volume: 27, Issue:7 Topics: Animals; Annexin A5; Antibodies; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Delivery Systems; Gemcitabine; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Nanostructures; Neoplasms, Experimental; Pancreatic Neoplasms; Peptides; RNA, Small Interfering	2019
Antipancreatic cancer effect of DNT cells and the underlying mechanism. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2019, Volume: 19, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Transplantation; Coculture Techniques; Deoxycytidine; Fas Ligand Protein; fas Receptor; Gemcitabine; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Pancreatic Neoplasms; T-Lymphocyte Subsets	2019
Ocoxin Oral Solution Exerts an Antitumoral Effect in Pancreatic Cancer and Reduces the Stromal-Mediated Chemoresistance. Pancreas, 2019, Volume: 48, Issue:4 Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Ascorbic Acid; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Resistance, Neoplasm; Folic Acid; Gemcitabine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Mice, Inbred C57BL; Neoplasms, Experimental; Paclitaxel; Pancreatic Neoplasms; Pantothenic Acid; Plant Extracts; Solutions; Vitamin B 12; Vitamin B 6; Zinc Sulfate	2019
A tissue-engineered subcutaneous pancreatic cancer model for antitumor drug evaluation. International journal of nanomedicine, 2013, Volume: 8 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Deoxycytidine; Female; Flow Cytometry; Gemcitabine; Humans; Mice, Nude; Nanofibers; Nanotechnology; Neoplasms, Experimental; Neoplastic Stem Cells; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Tissue Scaffolds; Tumor Cells, Cultured	2013
Comparative benefits of Nab-paclitaxel over gemcitabine or polysorbate-based docetaxel in experimental pancreatic cancer. Carcinogenesis, 2013, Volume: 34, Issue:10 Topics: Albumin-Bound Paclitaxel; Albumins; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Disease Models, Animal; Docetaxel; Female; Gemcitabine; Humans; Inhibitory Concentration 50; Neoplasms, Experimental; Paclitaxel; Pancreatic Neoplasms; Stathmin; Stromal Cells; Taxoids; Tubulin; Tumor Burden; Xenograft Model Antitumor Assays	2013
A predictive pharmacokinetic-pharmacodynamic model of tumor growth kinetics in xenograft mice after administration of anticancer agents given in combination. Cancer chemotherapy and pharmacology, 2013, Volume: 72, Issue:2 Topics: Algorithms; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Camptothecin; Cell Line, Tumor; Cisplatin; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Irinotecan; Kinetics; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Neoplasm Transplantation; Neoplasms, Experimental; Xenograft Model Antitumor Assays	2013
Synergy between chemotherapeutic agents and CTLA-4 blockade in preclinical tumor models. Cancer immunology, immunotherapy : CII, 2013, Volume: 62, Issue:9 Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; CTLA-4 Antigen; Deoxycytidine; Drug Synergism; Epothilones; Etoposide; Female; Gemcitabine; Ipilimumab; Mice; Mice, Inbred BALB C; Neoplasms, Experimental	2013
[Experimental study of remaxol as a drug for supportive therapy in traditional and high-dose treatment of tumors]. Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:5 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Deoxycytidine; Etoposide; Gemcitabine; Methotrexate; Mice; Neoplasms, Experimental; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Succinates	2013
Identification of preferred chemotherapeutics for combining with a CHK1 inhibitor. Molecular cancer therapeutics, 2013, Volume: 12, Issue:11 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carbolines; Cell Cycle Checkpoints; Checkpoint Kinase 1; Dacarbazine; Deoxycytidine; DNA Damage; Gemcitabine; HCT116 Cells; High-Throughput Nucleotide Sequencing; HT29 Cells; Humans; Irinotecan; Mice; Mice, Nude; Neoplasms; Neoplasms, Experimental; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Pyrroles; Temozolomide; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays	2013
MMP-2/9-oriented combinations enhance antitumor efficacy of EGFR/HER2-targeting fusion proteins and gemcitabine. Oncology reports, 2014, Volume: 32, Issue:1 Topics: Animals; Antibodies; Antineoplastic Agents; Cell Line, Tumor; Colorectal Neoplasms; Deoxycytidine; Doxycycline; Drug Therapy; Enediynes; ErbB Receptors; Female; Gemcitabine; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy; Neoplasms, Experimental; Recombinant Fusion Proteins; Treatment Outcome; Xenograft Model Antitumor Assays	2014
HS-104, a PI3K inhibitor, enhances the anticancer efficacy of gemcitabine in pancreatic cancer. International journal of oncology, 2014, Volume: 45, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Survival; Deoxycytidine; Drug Synergism; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Pancreatic Neoplasms; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Xenograft Model Antitumor Assays	2014
Dynamic contrast-enhanced ultrasonographic (DCE-US) assessment of the early response after combined gemcitabine and HIFU with low-power treatment for the mouse xenograft model of human pancreatic cancer. European radiology, 2014, Volume: 24, Issue:9 Topics: Animals; Contrast Media; Deoxycytidine; Gemcitabine; Heterografts; High-Intensity Focused Ultrasound Ablation; Humans; Immunosuppressive Agents; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Pancreatic Neoplasms; Ribonucleotide Reductases; Transplantation, Heterologous; Treatment Outcome; Ultrasonography	2014
The key role of calreticulin in immunomodulation induced by chemotherapeutic agents. International journal of clinical oncology, 2015, Volume: 20, Issue:2 Topics: Animals; Antigens, Surface; Antineoplastic Agents; Apoptosis; Calreticulin; Camptothecin; Carcinoma, Lewis Lung; CD3 Complex; Cell Line, Tumor; Cell Survival; Cisplatin; Colonic Neoplasms; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Histocompatibility Antigens Class I; Humans; Immunomodulation; Lymphocyte Count; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitomycin; Mitoxantrone; Neoplasm Transplantation; Neoplasms, Experimental; Protein Transport; T-Lymphocytes; Tumor Microenvironment	2015
Hyperthermia inhibits recombination repair of gemcitabine-stalled replication forks. Journal of the National Cancer Institute, 2014, Volume: 106, Issue:8 Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Cell Cycle; Cell Survival; Deoxycytidine; Disease Models, Animal; DNA Replication; DNA-Binding Proteins; DNA, Neoplasm; Drug Resistance, Neoplasm; Exonucleases; Gemcitabine; Humans; Hyperthermia, Induced; Liver Neoplasms; Mice; Mice, SCID; MRE11 Homologue Protein; Neoplasms, Experimental; Radio Waves; Radiofrequency Therapy; Recombinational DNA Repair	2014
Silencing of STRN4 suppresses the malignant characteristics of cancer cells. Cancer science, 2014, Volume: 105, Issue:12 Topics: Animals; Anoikis; Calmodulin-Binding Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Deoxycytidine; Gemcitabine; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HCT116 Cells; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Nerve Tissue Proteins; Pancreatic Neoplasms; RNA, Small Interfering	2014
Nintedanib, a triple angiokinase inhibitor, enhances cytotoxic therapy response in pancreatic cancer. Cancer letters, 2015, Mar-01, Volume: 358, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Gemcitabine; Humans; Indoles; Neoplasms, Experimental; Neovascularization, Pathologic; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Xenograft Model Antitumor Assays	2015
Cancer stem cell marker phenotypes are reversible and functionally homogeneous in a preclinical model of pancreatic cancer. Cancer research, 2015, Nov-01, Volume: 75, Issue:21 Topics: AC133 Antigen; Animals; Antigens, CD; Antigens, Ly; Antimetabolites, Antineoplastic; Biomarkers, Tumor; CD24 Antigen; Cell Transformation, Neoplastic; Deoxycytidine; Disease Models, Animal; Gemcitabine; Glycoproteins; Luciferases; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Neoplastic Stem Cells; Pancreas; Pancreatic Neoplasms; Peptides; Phenotype; Proto-Oncogene Proteins p21(ras); Pyrans; Spheroids, Cellular; Staining and Labeling; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2015
Synthesis of a Gemcitabine Prodrug for Remote Loading into Liposomes and Improved Therapeutic Effect. Bioconjugate chemistry, 2016, Jan-20, Volume: 27, Issue:1 Topics: Animals; Cell Line, Tumor; Chemistry Techniques, Synthetic; Deoxycytidine; Drug Delivery Systems; Drug Stability; Female; Gemcitabine; Inhibitory Concentration 50; Liposomes; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Prodrugs; Solubility	2016
Glaucarubinone Combined with Gemcitabine Improves Pancreatic Cancer Survival in an Immunocompetent Orthotopic Murine Model. Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2016, Volume: 29, Issue:6 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Proliferation; Deoxycytidine; Drug Screening Assays, Antitumor; Gemcitabine; Glaucarubin; Mice; Neoplasms, Experimental; Pancreatic Neoplasms	2016
In vitro and in vivo efficacy of afatinib as a single agent or in combination with gemcitabine for the treatment of nasopharyngeal carcinoma. Drug design, development and therapy, 2016, Volume: 10 Topics: Afatinib; Animals; Antineoplastic Agents; Carcinoma; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasms, Experimental; Quinazolines; Structure-Activity Relationship	2016
Enzyme-responsive peptide dendrimer-gemcitabine conjugate as a controlled-release drug delivery vehicle with enhanced antitumor efficacy. Acta biomaterialia, 2017, Volume: 55 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Delayed-Action Preparations; Dendrimers; Deoxycytidine; Female; Gemcitabine; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Peptides; Xenograft Model Antitumor Assays	2017
Inhibition of activation of dsRNA-dependent protein kinase and tumour growth inhibition. Cancer chemotherapy and pharmacology, 2009, Volume: 63, Issue:4 Topics: Animals; Antimetabolites, Antineoplastic; Blotting, Western; Cell Proliferation; Deoxycytidine; eIF-2 Kinase; Electrophoretic Mobility Shift Assay; Enzyme Activation; Fluorouracil; Gemcitabine; Mice; Neoplasms, Experimental; NF-kappa B; Phosphorylation; Proteasome Endopeptidase Complex; Protein Biosynthesis; Protein Kinase Inhibitors; Ribonucleotide Reductases; RNA, Double-Stranded	2009
Selective pulmonary artery perfusion followed by blood flow occlusion: new challenge for the treatment of pulmonary malignancies. Lung cancer (Amsterdam, Netherlands), 2009, Volume: 63, Issue:3 Topics: Animals; Antimetabolites, Antineoplastic; Catheterization; Deoxycytidine; Dose-Response Relationship, Drug; Embolization, Therapeutic; Female; Gemcitabine; Infusions, Intra-Arterial; Lung Neoplasms; Neoplasms, Experimental; Perfusion; Pulmonary Artery; Ribonucleotide Reductases; Swine; Treatment Outcome	2009
Superior preclinical efficacy of gemcitabine developed as chitosan nanoparticulate system. Biomacromolecules, 2011, Jan-10, Volume: 12, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Chitosan; Delayed-Action Preparations; Deoxycytidine; Drug Carriers; Gemcitabine; Humans; Kinetics; Mice; Mice, Inbred DBA; Nanoparticles; Neoplasms, Experimental	2011
Genetically modified tumour vaccines producing IL-12 augment chemotherapy of HPV16-associated tumours with gemcitabine. Oncology reports, 2011, Volume: 25, Issue:6 Topics: Animals; Antineoplastic Agents; Cancer Vaccines; Cell Separation; Combined Modality Therapy; Deoxycytidine; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gemcitabine; Genetic Therapy; Human papillomavirus 16; Interleukin-12; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Papillomavirus Infections	2011
DW-MRI as a biomarker to compare therapeutic outcomes in radiotherapy regimens incorporating temozolomide or gemcitabine in glioblastoma. PloS one, 2012, Volume: 7, Issue:4 Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Cell Line; Chemoradiotherapy; Dacarbazine; Deoxycytidine; Diffusion Magnetic Resonance Imaging; Drug Screening Assays, Antitumor; Gemcitabine; Glioblastoma; Humans; Kaplan-Meier Estimate; Mice; Mice, Transgenic; Neoplasms, Experimental; Radiation-Sensitizing Agents; Temozolomide; Treatment Outcome; Tumor Burden	2012
Preclinical combination therapy of clofarabine plus radiation. Nucleosides, nucleotides & nucleic acids, 2012, Volume: 31, Issue:9 Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Arabinonucleosides; Cell Line, Tumor; Clofarabine; Combined Modality Therapy; Deoxycytidine; Drug Evaluation, Preclinical; Gemcitabine; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Tumor Burden; Xenograft Model Antitumor Assays	2012
Activation of alpha-smooth muscle actin-positive myofibroblast-like cells after chemotherapy with gemcitabine in a rat orthotopic pancreatic cancer model. Journal of hepato-biliary-pancreatic sciences, 2013, Volume: 20, Issue:2 Topics: Actins; Animals; Antimetabolites, Antineoplastic; Blotting, Western; Cell Proliferation; Deoxycytidine; Gemcitabine; Immunohistochemistry; Male; Myofibroblasts; Neoplasms, Experimental; Pancreatic Neoplasms; Rats; Rats, Inbred Lew; Ribonucleotide Reductases; Transforming Growth Factor beta1; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A	2013
Low-dose gemcitabine depletes regulatory T cells and improves survival in the orthotopic Panc02 model of pancreatic cancer. International journal of cancer, 2013, Volume: 133, Issue:1 Topics: Administration, Metronomic; Animals; Antimetabolites, Antineoplastic; Carcinoma, Pancreatic Ductal; Cell Proliferation; Deoxycytidine; Flow Cytometry; Gemcitabine; Lymphocyte Count; Mice; Neoplasms, Experimental; Pancreatic Neoplasms; Survival Analysis; T-Lymphocytes, Regulatory	2013
Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas. The American journal of pathology, 2002, Volume: 161, Issue:3 Topics: Animals; Antineoplastic Agents; Deoxycytidine; Endothelium, Vascular; ErbB Receptors; Gemcitabine; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; Paclitaxel; Pyrimidines; Pyrroles; Signal Transduction; Tumor Cells, Cultured	2002
Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity. Molecular cancer therapeutics, 2002, Volume: 1, Issue:6 Topics: Animals; Antimetabolites, Antineoplastic; Blotting, Western; Cytidine Deaminase; Deoxycytidine; Deoxycytidine Kinase; DNA Primers; Female; Gemcitabine; Humans; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Skin Neoplasms	2002
[Preclinical studies of concomitant chemoradiation]. Medicina (Kaunas, Lithuania), 2003, Volume: 39, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Child; Combined Modality Therapy; Deoxycytidine; Female; Gemcitabine; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Paclitaxel; Radiation Tolerance; Time Factors; Topotecan; Transplantation, Heterologous	2003
Administration of optimal biological dose and schedule of interferon alpha combined with gemcitabine induces apoptosis in tumor-associated endothelial cells and reduces growth of human pancreatic carcinoma implanted orthotopically in nude mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:5 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Division; Deoxycytidine; Dose-Response Relationship, Drug; Endothelium, Vascular; Fibroblast Growth Factor 2; Gemcitabine; Humans; Implants, Experimental; Interferon-alpha; Interleukin-8; Male; Matrix Metalloproteinase 9; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Pancreatic Neoplasms; Platelet Endothelial Cell Adhesion Molecule-1; Survival Rate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A	2003
Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors. Cancer research, 2003, Aug-01, Volume: 63, Issue:15 Topics: Animals; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; CD4-Positive T-Lymphocytes; CD40 Antigens; CD8-Positive T-Lymphocytes; Combined Modality Therapy; Deoxycytidine; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; Hemagglutinins; Immunotherapy; Lymphocytes, Tumor-Infiltrating; Mesothelioma; Mice; Mice, Inbred BALB C; Neoplasms, Experimental	2003
Low-dose radioimmunotherapy ((90)Y-PAM4) combined with gemcitabine for the treatment of experimental pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Sep-01, Volume: 9, Issue:10 Pt 2 Topics: Animals; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Cell Line, Tumor; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Gemcitabine; Humans; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pancreatic Neoplasms; Radioimmunotherapy; Time Factors; Tissue Distribution; Yttrium Radioisotopes	2003
Combined 90Yttrium-DOTA-labeled PAM4 antibody radioimmunotherapy and gemcitabine radiosensitization for the treatment of a human pancreatic cancer xenograft. International journal of cancer, 2004, Apr-20, Volume: 109, Issue:4 Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Body Weight; Combined Modality Therapy; Deoxycytidine; Female; Gemcitabine; Heterocyclic Compounds; Humans; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasms, Experimental; Organometallic Compounds; Pancreatic Neoplasms; Radiation-Sensitizing Agents; Radioimmunotherapy; Survival Rate; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Yttrium Radioisotopes	2004
Non-toxic and short treatment with gemcitabine inhibits in vitro migration of HT-1080 cells. Anti-cancer drugs, 2004, Volume: 15, Issue:8 Topics: Cell Cycle; Cell Division; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Deoxycytidine; Drug Administration Schedule; Drug Screening Assays, Antitumor; Fibrosarcoma; France; Gemcitabine; Humans; Inhibitory Concentration 50; Neoplasms, Experimental; Time Factors	2004
Combination of gemcitabine and Ad5/3-Delta24, a tropism modified conditionally replicating adenovirus, for the treatment of ovarian cancer. Gene therapy, 2005, Volume: 12, Issue:15 Topics: Adenocarcinoma; Adenovirus E1A Proteins; Adenoviruses, Human; Animals; Antiviral Agents; Bone Marrow Cells; Cell Line, Tumor; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Drug; Female; Gemcitabine; Genetic Therapy; Liver; Mice; Neoplasms, Experimental; Oncolytic Virotherapy; Oncolytic Viruses; Ovarian Neoplasms; Virus Replication	2005
Synergistic anti-tumor effect of recombinant human endostatin adenovirus combined with gemcitabine. Anti-cancer drugs, 2005, Volume: 16, Issue:5 Topics: Adenoviridae; Animals; Antineoplastic Agents; Cell Line, Tumor; Deoxycytidine; Drug Synergism; Endostatins; Female; Gemcitabine; Genetic Therapy; Genetic Vectors; Humans; Injections, Intralesional; Injections, Intraperitoneal; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; Recombinant Proteins; Xenograft Model Antitumor Assays	2005
Combination therapy for advanced pancreatic cancer using Herceptin plus chemotherapy. International journal of oncology, 2005, Volume: 27, Issue:4 Topics: Agar; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascites; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Deoxycytidine; Docetaxel; Drug Resistance, Neoplasm; Gemcitabine; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Pancreatic Neoplasms; Recombinant Proteins; Taxoids; Time Factors; Trastuzumab	2005
Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Sep-15, Volume: 11, Issue:18 Topics: Adenoviridae; Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; B-Lymphocytes; CD11b Antigen; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line; Cell Line, Tumor; Deoxycytidine; Female; Flow Cytometry; Gemcitabine; Genetic Therapy; Genetic Vectors; Immunotherapy; Interferon-beta; Killer Cells, Natural; Lymphocyte Count; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Necrosis; Neoplasms, Experimental; Receptors, Chemokine; Spleen; T-Lymphocytes, Cytotoxic; Time Factors	2005
Serum amyloid A as a tumor marker in sera of nude mice with orthotopic human pancreatic cancer and in plasma of patients with pancreatic cancer. International journal of oncology, 2005, Volume: 27, Issue:5 Topics: Animals; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Deoxycytidine; Disease Progression; Gemcitabine; Humans; Male; Mice; Mice, Nude; Neoplasm Staging; Neoplasms, Experimental; Pancreatic Neoplasms; Random Allocation; Sensitivity and Specificity; Serum Amyloid A Protein; Transplantation, Heterologous	2005
Gemcitabine aerosol: in vitro antitumor activity and deposition imaging for preclinical safety assessment in baboons. Cancer chemotherapy and pharmacology, 2006, Volume: 58, Issue:2 Topics: Aerosols; Animals; Deoxycytidine; Female; Gemcitabine; Lung Neoplasms; Models, Animal; Neoplasms, Experimental; Papio; Radionuclide Imaging	2006
Gene therapy based on gemcitabine chemosensitization suppresses pancreatic tumor growth. Molecular therapy : the journal of the American Society of Gene Therapy, 2006, Volume: 14, Issue:6 Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Survival; Cricetinae; Deoxycytidine; Deoxycytidine Kinase; Gemcitabine; Genetic Therapy; Genetic Vectors; Male; Mesocricetus; Neoplasms, Experimental; Nucleoside-Phosphate Kinase; Pancreatic Neoplasms	2006
Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. The Journal of experimental medicine, 2007, Jan-22, Volume: 204, Issue:1 Topics: Adoptive Transfer; Animals; Antigen Presentation; Antigen-Presenting Cells; Antigens, Neoplasm; Antineoplastic Agents; Cell Line, Tumor; Deoxycytidine; Gemcitabine; Immunization; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Experimental; Receptors, Antigen, T-Cell; Stromal Cells; T-Lymphocytes, Cytotoxic	2007
19F NMR in vivo spectroscopy reflects the effectiveness of perfusion-enhancing vascular modifiers for improving gemcitabine chemotherapy. Magnetic resonance in medicine, 2008, Volume: 59, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Botulinum Toxins, Type A; Carcinoma, Hepatocellular; Deoxycytidine; Drug Synergism; Fluorine Radioisotopes; Gemcitabine; Magnetic Resonance Spectroscopy; Male; Mice; Neoplasms, Experimental; Peptides, Cyclic; Thalidomide	2008
Real-time high-resolution compound imaging allows percutaneous initiation and surveillance in an orthotopic murine pancreatic cancer model. Pancreas, 2008, Volume: 36, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deoxycytidine; Disease Progression; Female; Gemcitabine; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Pancreatic Neoplasms; Time Factors; Ultrasonography, Interventional	2008
The influence of BIBW22BS, a dipyridamole derivative, on the antiproliferative effects of 5-fluorouracil, methotrexate and gemcitabine in vitro and in human tumour xenografts. European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:13-14 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Deoxycytidine; Dipyridamole; Doxorubicin; Drug Resistance; Female; Floxuridine; Fluorouracil; Gemcitabine; Humans; Methotrexate; Mice; Mice, Nude; Morpholines; Neoplasms; Neoplasms, Experimental; Protein Binding; Transplantation, Heterologous; Triamterene; Tumor Cells, Cultured; Vincristine	1995
Enhancement of tumor radioresponse in vivo by gemcitabine. Cancer research, 1999, Jan-01, Volume: 59, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Combined Modality Therapy; Deoxycytidine; DNA Replication; Dose-Response Relationship, Drug; Gemcitabine; Mice; Neoplasms, Experimental; Radiation-Sensitizing Agents	1999
Tumor biology: use of tiled images in conjunction with measurements of cellular proliferation and death in response to drug treatments. Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:8 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Division; Colonic Neoplasms; Cyclophosphamide; Deoxycytidine; Female; Gemcitabine; Humans; Image Processing, Computer-Assisted; Lung Neoplasms; Mice; Mice, Nude; Mitomycin; Neoplasms, Experimental; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2000
Tumor uptake and elimination of 2',2'-difluoro-2'-deoxycytidine (gemcitabine) after deoxycytidine kinase gene transfer: correlation with in vivo tumor response. Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:10 Topics: Animals; Cell Division; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Deoxycytidine; Deoxycytidine Kinase; Female; Fluorine; Gemcitabine; Gene Expression Regulation, Enzymologic; Gene Transfer Techniques; HT29 Cells; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Neoplasms, Experimental; Xenograft Model Antitumor Assays	2001
Wortmannin inhibits pkb/akt phosphorylation and promotes gemcitabine antitumor activity in orthotopic human pancreatic cancer xenografts in immunodeficient mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:10 Topics: Androstadienes; Animals; Antimetabolites, Antineoplastic; Cell Division; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; ErbB Receptors; Gemcitabine; Humans; Immunohistochemistry; Male; Mice; Mice, SCID; Neoplasms, Experimental; Pancreatic Neoplasms; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Receptor, ErbB-2; Tumor Cells, Cultured; Wortmannin; Xenograft Model Antitumor Assays	2001
Activity of 2',2'-difluorodeoxycytidine (Gemcitabine) against human tumor colony forming units. Anti-cancer drugs, 1992, Volume: 3, Issue:2 Topics: Antimetabolites, Antineoplastic; Deamination; Deoxycytidine; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Neoplasms, Experimental; Tetrahydrouridine; Tumor Cells, Cultured; Tumor Stem Cell Assay	1992
Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine). Cancer research, 1990, Jul-15, Volume: 50, Issue:14 Topics: Animals; Antimetabolites, Antineoplastic; Cell Line; Cell Survival; Deoxycytidine; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Gemcitabine; Humans; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Neoplasms, Experimental; Tumor Cells, Cultured	1990