Page last updated: 2024-08-24

gemcitabine and Astrocytoma, Grade IV

gemcitabine has been researched along with Astrocytoma, Grade IV in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	8 (28.57)	29.6817
2010's	16 (57.14)	24.3611
2020's	4 (14.29)	2.80

Authors

Authors	Studies
Burgess, K; Jiang, Z; Kuai, D; Pflug, K; Sitcheran, R; Usama, SM; Yan, X	1
Bastiat, G; Bertrand, N; Bozzato, E; Eyer, J; Farooq, U; Gazaille, C; Madadian-Bozorg, N; Mellinger, A; Préat, V; Saulnier, P; Sicot, M	1
Benoit, JP; Bronte, V; Della Puppa, A; Ingangi, V; Lollo, G; Magri, S; Mandruzzato, S; Marigo, I; Masetto, E; Matha, K; Pinton, L; Schibuola, I; Vettore, M	1
Al-Youbi, AO; Bashammakh, AS; El-Shahawi, MS; Graham, RM; Leblanc, RM; Liyanage, PY; Vanni, S; Zhou, Y	1
Courcelle, M; Djaker, N; Palama, T; Sahli, F; Savarin, P; Spadavecchia, J	1
Bastiancich, C; Bastiat, G; Bianco, J; Danhier, F; Gallez, B; Joudiou, N; Lagarce, F; Préat, V; Ucakar, B; Vanvarenberg, K	1
Bastiancich, C; Bastiat, G; Lagarce, F	1
Chen, T; Fu, Y; Gong, T; Huang, T; Li, W; Liu, X; Yang, Q; Zhang, Z	1
Bastiancich, C; Bastiat, G; Bianco, J; Danhier, F; Franconi, F; Lagarce, F; Lemaire, L; Préat, V	1
Bastiancich, C; Bastiat, G; Bozzato, E; Danhier, F; Luyten, U; Préat, V	1
Altinoz, MA; Bilir, A; Elmaci, İ; Ozpinar, A	1
Brons, S; Combs, SE; Debus, J; Haberer, T; Schlaich, F; Weber, KJ	1
Bynoe, MS; Kim, DG	1
Kim, JS; Lee, SJ; Ryu, JH; Shin, DH	1
Bastiancich, C; Bastiat, G; Danhier, F; Lagarce, F; Pitorre, M; Préat, V; Ucakar, B; Vanvarenberg, K	1
Bindra, R; Couvreur, P; Desmaële, D; Gaudin, A; King, AR; Saltzman, WM; Saucier-Sawyer, JK; Song, E	1
Baayen, JC; Bergman, AM; de Lange, SM; Dirven, CM; Giaccone, G; Honeywell, RJ; Laan, AC; Peters, GJ; Postma, TJ; Sigmond, J; van der Born, K; Van Groeningen, CJ	1
Carapella, CM; Carosi, M; Cognetti, F; Fabi, A; Giannarelli, D; Maschio, M; Metro, G; Mirri, MA; Pace, A; Pellegrini, D; Pompili, A; Russillo, M; Vidiri, A	1
Brons, S; Combs, SE; Debus, J; Haberer, T; Habermehl, D; Rieken, S; Weber, KJ; Winter, M; Zipp, L	1
Chenevert, TL; Galbán, CJ; Galbán, S; Heist, KA; Holland, EC; Johnson, TD; Lawrence, TS; Lemasson, B; Leopold, JS; Li, F; Mikkelsen, T; Rehemtulla, A; Ross, BD; Williams, TM	1
Armesilla, AL; Bian, X; Brown, S; Channathodiyil, P; Darling, JL; Goktug, T; Guichet, PO; Hugnot, JP; Kannappan, V; Liu, P; Wang, W	1
Bamberg, M; Dichgans, J; Duffner, F; Hermisson, M; Kortmann, RD; Küker, WM; Weller, M; Wick, W	1
Ostruszka, LJ; Shewach, DS	2
Barten-van Rijbroek, A; Castro Kreder, N; Genç, M; Haveman, J; Stalpers, LJ	1
Arcangeli, G; Carapella, CM; Carosi, MA; Cognetti, F; Fabi, A; Felici, A; Iandolo, B; Metro, G; Mirri, A; Occhipinti, E; Pace, A; Vidiri, A	1
Belanger, K; Forsyth, P; Fulton, D; Gertler, SZ; Goodyear, M; MacDonald, D; Perry, J; Seymour, L; Steward, W; Stewart, DJ; Wainman, N	1
Bamberg, M; Dichgans, J; Heiss, E; Kortmann, RD; Küker, W; Meyermann, R; Streffer, J; Weller, M; Wick, W	1

Reviews

1 review(s) available for gemcitabine and Astrocytoma, Grade IV

Article	Year
Gemcitabine and glioblastoma: challenges and current perspectives. Drug discovery today, 2018, Volume: 23, Issue:2 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Deoxycytidine; Gemcitabine; Glioblastoma; Humans; Nanomedicine; Radiation-Sensitizing Agents	2018

Trials

6 trial(s) available for gemcitabine and Astrocytoma, Grade IV

Article	Year
Gemcitabine uptake in glioblastoma multiforme: potential as a radiosensitizer. Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:1 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Biological Availability; Biopsy; Brain Neoplasms; Cytidine Deaminase; Deoxycytidine; Deoxycytidine Kinase; Female; Floxuridine; Gemcitabine; Glioblastoma; Humans; Male; Middle Aged; Nucleoside Deaminases; Radiation-Sensitizing Agents	2009
Phase II study of fixed dose rate gemcitabine as radiosensitizer for newly diagnosed glioblastoma multiforme. Cancer chemotherapy and pharmacology, 2010, Volume: 65, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Deoxycytidine; DNA Modification Methylases; DNA Repair Enzymes; Female; Gemcitabine; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Promoter Regions, Genetic; Radiation-Sensitizing Agents; Tumor Suppressor Proteins	2010
Neoadjuvant gemcitabine/treosulfan chemotherapy for newly diagnosed glioblastoma: a phase II study. Journal of neuro-oncology, 2002, Volume: 59, Issue:2 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Busulfan; Deoxycytidine; Disease-Free Survival; Drug Therapy, Combination; Female; Gemcitabine; Glioblastoma; Hematologic Diseases; Humans; Male; Middle Aged; Neoadjuvant Therapy; Venous Thrombosis	2002
Fixed dose-rate gemcitabine as radiosensitizer for newly diagnosed glioblastoma: a dose-finding study. Journal of neuro-oncology, 2008, Volume: 87, Issue:1 Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Deoxycytidine; Female; Gemcitabine; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Maximum Tolerated Dose; Middle Aged; Radiation-Sensitizing Agents; Survival Analysis; Survival Rate	2008
NCIC-CTG phase II study of gemcitabine in patients with malignant glioma (IND.94). Annals of oncology : official journal of the European Society for Medical Oncology, 2000, Volume: 11, Issue:3 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Deoxycytidine; Female; Gemcitabine; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Steroids	2000
Preirradiation gemcitabine chemotherapy for newly diagnosed glioblastoma. A phase II study. Cancer, 2001, Jan-15, Volume: 91, Issue:2 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Deoxycytidine; Female; Gemcitabine; Glioblastoma; Humans; Infusions, Intravenous; Leukopenia; Male; Middle Aged; Prospective Studies; Radiation-Sensitizing Agents; Radiotherapy Dosage; Thrombocytopenia	2001

Other Studies

21 other study(ies) available for gemcitabine and Astrocytoma, Grade IV

Article	Year
Cyanine-Gemcitabine Conjugates as Targeted Theranostic Agents for Glioblastoma Tumor Cells. Journal of medicinal chemistry, 2019, 10-24, Volume: 62, Issue:20 Topics: Animals; Antineoplastic Agents; Carbocyanines; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Stability; Female; Gemcitabine; Glioblastoma; Humans; Mice; Mice, Nude; Theranostic Nanomedicine; Tissue Distribution; Transplantation, Heterologous	2019
Glioblastoma-targeted, local and sustained drug delivery system based on an unconventional lipid nanocapsule hydrogel. Biomaterials advances, 2023, Volume: 153 Topics: Animals; Brain Neoplasms; Drug Delivery Systems; Gemcitabine; Glioblastoma; Humans; Hydrogels; Lipids; Mice; Nanocapsules	2023
Targeting of immunosuppressive myeloid cells from glioblastoma patients by modulation of size and surface charge of lipid nanocapsules. Journal of nanobiotechnology, 2020, Feb-17, Volume: 18, Issue:1 Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Membrane Permeability; Deoxycytidine; Drug Compounding; Endocytosis; Gemcitabine; Glioblastoma; Humans; Immunosuppressive Agents; Immunotherapy; Leukocytes; Lipids; Macrophages; Myeloid-Derived Suppressor Cells; Nanocapsules; Particle Size; Signal Transduction; Surface Properties	2020
Pediatric glioblastoma target-specific efficient delivery of gemcitabine across the blood-brain barrier via carbon nitride dots. Nanoscale, 2020, Apr-14, Volume: 12, Issue:14 Topics: Animals; Antimetabolites, Antineoplastic; Blood-Brain Barrier; Brain Neoplasms; Cell Line; Cell Survival; Deoxycytidine; Drug Carriers; Gemcitabine; Glioblastoma; Humans; Larva; Nitriles; Quantum Dots; Transferrin; Zebrafish	2020
Temozolomide, Gemcitabine, and Decitabine Hybrid Nanoconjugates: From Design to Proof-of-Concept (PoC) of Synergies toward the Understanding of Drug Impact on Human Glioblastoma Cells. Journal of medicinal chemistry, 2020, 07-09, Volume: 63, Issue:13 Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Decitabine; Deoxycytidine; Drug Delivery Systems; Drug Liberation; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; Glioblastoma; Gold; Humans; Magnetic Resonance Spectroscopy; Metal Nanoparticles; Nanoconjugates; Proof of Concept Study; Spectrophotometry, Ultraviolet; Temozolomide	2020
Injectable nanomedicine hydrogel for local chemotherapy of glioblastoma after surgical resection. Journal of controlled release : official journal of the Controlled Release Society, 2017, Oct-28, Volume: 264 Topics: Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Deoxycytidine; Female; Gemcitabine; Glioblastoma; Humans; Hydrogels; Injections; Lipids; Mice; Nanocapsules; Nanomedicine; Xenograft Model Antitumor Assays	2017
Hyaluronic Acid-Modified Micelles Encapsulating Gem-C Molecular pharmaceutics, 2018, 03-05, Volume: 15, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Brain Neoplasms; Cell Line, Tumor; Deoxycytidine; Drug Carriers; Drug Compounding; Gemcitabine; Glioblastoma; Humans; Hyaluronan Receptors; Hyaluronic Acid; Lignans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanoparticles; Rats; Rats, Sprague-Dawley; Spheroids, Cellular; Survival Rate; Treatment Outcome; Xenograft Model Antitumor Assays	2018
Evaluation of lauroyl-gemcitabine-loaded hydrogel efficacy in glioblastoma rat models. Nanomedicine (London, England), 2018, Volume: 13, Issue:16 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Deoxycytidine; Female; Gemcitabine; Glioblastoma; Hydrogels; Magnetic Resonance Imaging; Nanomedicine; Rats; Rats, Sprague-Dawley	2018
Drug combination using an injectable nanomedicine hydrogel for glioblastoma treatment. International journal of pharmaceutics, 2019, Mar-25, Volume: 559 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Deoxycytidine; Drug Carriers; Drug Combinations; Drug Liberation; Gemcitabine; Glioblastoma; Hydrogels; Injections; Lipids; Mice; Nanocapsules; Nanomedicine; Paclitaxel; Rats	2019
Gemcitabine, vinorelbine and cyclooxygenase inhibitors in the treatment of glioblastoma. Ultrastructural analyses in C6 glioma in vitro. Tissue & cell, 2019, Volume: 59 Topics: Antineoplastic Combined Chemotherapy Protocols; Autophagic Cell Death; Cyclooxygenase Inhibitors; Deoxycytidine; Gemcitabine; Glioblastoma; Humans; Vinorelbine	2019
Comparison of the effects of photon versus carbon ion irradiation when combined with chemotherapy in vitro. Radiation oncology (London, England), 2013, Nov-06, Volume: 8 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carbon; Cell Cycle; Cell Line, Tumor; Cell Separation; Chemoradiotherapy; Cisplatin; Colonic Neoplasms; Deoxycytidine; Dose-Response Relationship, Radiation; Drug Screening Assays, Antitumor; Flow Cytometry; Gemcitabine; Glioblastoma; Humans; Ions; Lung Neoplasms; Paclitaxel; Pancreatic Neoplasms; Photons; Propidium; Radiotherapy; Relative Biological Effectiveness; Time Factors	2013
A2A Adenosine Receptor Regulates the Human Blood-Brain Barrier Permeability. Molecular neurobiology, 2015, Volume: 52, Issue:1 Topics: Adenosine A2 Receptor Agonists; Adherens Junctions; Animals; Antineoplastic Agents; Blood-Brain Barrier; Cell Death; Cell Line; Cell Membrane Permeability; Cell Movement; Deoxycytidine; Down-Regulation; Electric Impedance; Endothelial Cells; Focal Adhesions; Gemcitabine; Glioblastoma; Humans; Jurkat Cells; Mice, Inbred C57BL; Phosphorylation; Receptors, Adenosine A2; rhoA GTP-Binding Protein; Signal Transduction; Stress Fibers; T-Lymphocytes; Tight Junctions	2015
Synergistic Effect of Immunoliposomal Gemcitabine and Bevacizumab in Glioblastoma Stem Cell-Targeted Therapy. Journal of biomedical nanotechnology, 2015, Volume: 11, Issue:11 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Bevacizumab; Deoxycytidine; Drug Delivery Systems; Drug Synergism; Gemcitabine; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Liposomes; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Xenograft Model Antitumor Assays	2015
Lauroyl-gemcitabine-loaded lipid nanocapsule hydrogel for the treatment of glioblastoma. Journal of controlled release : official journal of the Controlled Release Society, 2016, Mar-10, Volume: 225 Topics: Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Deoxycytidine; Drug Liberation; Female; Gemcitabine; Glioblastoma; Humans; Hydrogels; Injections; Lipids; Mice, Nude; Nanocapsules; Needles; Rheology; Tumor Burden	2016
PEGylated squalenoyl-gemcitabine nanoparticles for the treatment of glioblastoma. Biomaterials, 2016, Volume: 105 Topics: Absorption, Physicochemical; Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Deoxycytidine; Diffusion; Dose-Response Relationship, Drug; Gemcitabine; Glioblastoma; Humans; Molecular Imaging; Nanocapsules; Polyethylene Glycols; Rats; Squalene; Treatment Outcome	2016
In vitro evaluation of photon and carbon ion radiotherapy in combination with chemotherapy in glioblastoma cells. Radiation oncology (London, England), 2012, Jan-27, Volume: 7 Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carbon; Cell Line, Tumor; Chemoradiotherapy; Cisplatin; Deoxycytidine; Dose-Response Relationship, Radiation; Gemcitabine; Glioblastoma; Humans; In Vitro Techniques; Paclitaxel; Photons; Tumor Stem Cell Assay	2012
DW-MRI as a biomarker to compare therapeutic outcomes in radiotherapy regimens incorporating temozolomide or gemcitabine in glioblastoma. PloS one, 2012, Volume: 7, Issue:4 Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Cell Line; Chemoradiotherapy; Dacarbazine; Deoxycytidine; Diffusion Magnetic Resonance Imaging; Drug Screening Assays, Antitumor; Gemcitabine; Glioblastoma; Humans; Kaplan-Meier Estimate; Mice; Mice, Transgenic; Neoplasms, Experimental; Radiation-Sensitizing Agents; Temozolomide; Treatment Outcome; Tumor Burden	2012
Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells. British journal of cancer, 2012, Oct-23, Volume: 107, Issue:9 Topics: Aldehyde Dehydrogenase; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Copper; Cytotoxicity, Immunologic; Deoxycytidine; Disulfiram; Drug Synergism; Gemcitabine; Glioblastoma; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Neoplastic Stem Cells; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species	2012
The role of DNA synthesis inhibition in the cytotoxicity of 2',2'-difluoro-2'-deoxycytidine. Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:4 Topics: Antineoplastic Agents; Aphidicolin; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Deoxycytidine; DNA, Neoplasm; Enzyme Inhibitors; Gemcitabine; Glioblastoma; Humans; Hydroxyurea; Nucleic Acid Synthesis Inhibitors; Pyrimidine Nucleosides; Ribonucleotide Reductases	2003
Enhancement of effects of irradiation by gemcitabine in a glioblastoma cell line and cell line spheroids. Journal of cancer research and clinical oncology, 2004, Volume: 130, Issue:1 Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Deoxycytidine; Gemcitabine; Glioblastoma; Humans; Radiation-Sensitizing Agents; Spheroids, Cellular	2004
The role of cell cycle progression in radiosensitization by 2',2'-difluoro-2'-deoxycytidine. Cancer research, 2000, Nov-01, Volume: 60, Issue:21 Topics: Adenosine Triphosphate; Apoptosis; Bromodeoxyuridine; Cell Cycle; Deoxyadenine Nucleotides; Deoxycytidine; Gemcitabine; Glioblastoma; Humans; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2000