Page last updated: 2024-08-24

gemcitabine and Acute Myelogenous Leukemia

gemcitabine has been researched along with Acute Myelogenous Leukemia in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (68.75)29.6817
2010's5 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baker, SD; Buelow, DR; Cotton, A; Dang, J; Drenberg, CD; Fu, Q; Gruber, TA; Guy, RK; Hu, S; Inaba, H; Jeon, JY; Li, M; Orwick, SJ; Pioso, M; Ribeiro, RC; Rubnitz, JE; Shelat, A1
Annereau, JP; Bailly, C; Bonnet, D; Brel, V; Créancier, L; Currie, E; Fournier, E; Gomes, B; Guilbaud, N; Guminski, Y; Kruczynski, A; Pillon, A; Vandenberghe, I1
Borders, EB; Cherry, MA; Herman, T; Holter, J; Selby, GB; Srour, SA1
Berda, Y; Ciccolini, J; Costello, R; Fanciullino, R; Fina, F; Lacarelle, B; Mercier, C; Ouafik, L; Serdjebi, C1
Baker, SD; Blum, W; Drenberg, CD; Du, G; Gibson, AA; Gruber, TA; Hu, S; Li, L; Nies, AT; Pabla, N; Pounds, SB; Rhinehart, DP; Schwab, M; Shi, L; Sparreboom, A1
Adams, DJ; Decastro, CM; Gockerman, JP; Moore, JO; Peterson, BL; Petros, WP; Rao, AV; Rizzieri, DA; Sand, GJ; Spasojevic, I; Younis, IR1
Apostolidou, E; Cortes, J; Estey, E; Faderl, S; Garcia-Manero, G; Giles, FJ; Kantarjian, H; Thomas, D; Tsimberidou, A1
Adams, DJ; Chao, NJ; DeCastro, CM; Foster, T; Gasparetto, C; Gockerman, JP; Ibom, VK; Long, GD; Moore, JO; Payne, N; Rizzieri, DA; Rosner, GL; Thompson, M; Vredenburgh, JJ1
Cortes, J; Giles, F; Kantarjian, H; Ravandi, F1
Angiolillo, AL; Chen, Z; Krailo, M; Reaman, G; Whitlock, J1
Hudson, MM1
Boos, J; Henze, G; von Stackelberg, A; Wagner-Bohn, A1
Adema, AD; Albertoni, F; Floor, K; Hubeek, I; Kaspers, GJ; Peters, GJ; Zuurbier, L1
Azuma, A; Huang, P; Li, YX; Plunkett, W; Sampath, D; Shi, Z1
Azuma, A; Huang, P; Matsuda, A; Plunkett, W1
Ayres, M; Du, M; Estey, EH; Gandhi, V; Plunkett, W1

Reviews

1 review(s) available for gemcitabine and Acute Myelogenous Leukemia

ArticleYear
New agents in acute myeloid leukemia and other myeloid disorders.
    Cancer, 2004, Feb-01, Volume: 100, Issue:3

    Topics: Antineoplastic Agents; Cyclosporine; Cytosine; Deoxycytidine; Dioxolanes; Female; Gemcitabine; Humans; Immunosuppressive Agents; Immunotherapy; Leukemia, Myeloid, Acute; Male; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Severity of Illness Index; Survival Analysis; Treatment Outcome

2004

Trials

6 trial(s) available for gemcitabine and Acute Myelogenous Leukemia

ArticleYear
Phase I evaluation of gemcitabine, mitoxantrone, and their effect on plasma disposition of fludarabine in patients with relapsed or refractory acute myeloid leukemia.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Drug Synergism; Female; Gemcitabine; Half-Life; Humans; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Salvage Therapy; Tissue Distribution; Vidarabine

2008
Mitoxantrone and prolonged infusion gemcitabine as salvage therapy in patients with acute myelogenous leukemia.
    Leukemia research, 2003, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Deoxycytidine; Gemcitabine; Humans; Infusions, Parenteral; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Mouth Mucosa; Pilot Projects; Remission Induction; Salvage Therapy; Sepsis; Stomatitis; Treatment Outcome

2003
Phase I evaluation of prolonged-infusion gemcitabine with fludarabine for relapsed or refractory acute myelogenous leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Deoxycytidine; Esophagitis; Gemcitabine; Humans; Infusions, Intravenous; Injections, Intravenous; Leukemia, Myeloid, Acute; Metabolic Clearance Rate; Middle Aged; Recurrence; Stomatitis; Vidarabine

2003
Phase II study of gemcitabine in children with relapsed acute lymphoblastic leukemia or acute myelogenous leukemia (ADVL0022): a Children's Oncology Group Report.
    Pediatric blood & cancer, 2006, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Child; Child, Preschool; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Humans; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Failure

2006
Phase II study of gemcitabine in children with relapsed leukemia.
    Pediatric blood & cancer, 2006, Volume: 46, Issue:2

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Deoxycytidine; Female; Gemcitabine; Humans; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence

2006
Prolonged infusion of gemcitabine: clinical and pharmacodynamic studies during a phase I trial in relapsed acute myelogenous leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Feb-01, Volume: 20, Issue:3

    Topics: Antimetabolites, Antineoplastic; Deoxycytidine; DNA; Female; Gemcitabine; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male

2002

Other Studies

9 other study(ies) available for gemcitabine and Acute Myelogenous Leukemia

ArticleYear
A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML.
    Nature communications, 2019, 05-16, Volume: 10, Issue:1

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Cell Line, Tumor; Child; Child, Preschool; Cytarabine; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; High-Throughput Screening Assays; Humans; Infant; Janus Kinase Inhibitors; Leukemia, Experimental; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Taxoids; Whole-Body Irradiation; Xenograft Model Antitumor Assays; Young Adult

2019
F14512, a polyamine-vectorized anti-cancer drug, currently in clinical trials exhibits a marked preclinical anti-leukemic activity.
    Leukemia, 2013, Volume: 27, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Proliferation; Cytarabine; Deoxycytidine; Doxorubicin; Fetal Blood; Flow Cytometry; Gemcitabine; Humans; Hydroxamic Acids; Immunoenzyme Techniques; Interleukin Receptor Common gamma Subunit; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Podophyllotoxin; Pyrazines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Tumor Cells, Cultured; Vorinostat; Xenograft Model Antitumor Assays

2013
Role of topotecan, vinorelbine, thiotepa and gemcitabine chemotherapy in relapsed/refractory adult acute leukemia.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retreatment; Thiotepa; Topotecan; Treatment Outcome; Vinblastine; Vinorelbine

2015
Lethal toxicity after administration of azacytidine: implication of the cytidine deaminase-deficiency syndrome.
    Pharmacogenetics and genomics, 2015, Volume: 25, Issue:6

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Cytidine Deaminase; Deoxycytidine; Fatal Outcome; Gemcitabine; Humans; Inactivation, Metabolic; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Polymorphism, Single Nucleotide

2015
OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues.
    Cancer research, 2017, 04-15, Volume: 77, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Child; CHO Cells; Cohort Studies; Cricetulus; Cytarabine; Deoxycytidine; Dipyridamole; Drug Resistance, Neoplasm; Gemcitabine; Gene Expression Profiling; HEK293 Cells; HeLa Cells; Humans; Leukemia, Myeloid, Acute; Organic Cation Transport Proteins; Symporters

2017
Achieving cure for early stage pediatric Hodgkin disease with minimal morbidity: are we there yet?
    Pediatric blood & cancer, 2006, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Child; Child, Preschool; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Humans; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Failure

2006
Cellular resistance against troxacitabine in human cell lines and pediatric patient acute myeloid leukemia blast cells.
    Nucleosides, nucleotides & nucleic acids, 2006, Volume: 25, Issue:9-11

    Topics: Antineoplastic Agents; Catalysis; Cell Line, Tumor; Cladribine; Cytosine; Deoxycytidine; Dioxolanes; Drug Resistance, Neoplasm; Gemcitabine; HeLa Cells; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia, Myeloid, Acute; Models, Chemical; Nucleosides

2006
S-Phase arrest by nucleoside analogues and abrogation of survival without cell cycle progression by 7-hydroxystaurosporine.
    Cancer research, 2001, Feb-01, Volume: 61, Issue:3

    Topics: Alkaloids; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Gemcitabine; Humans; Leukemia, Myeloid, Acute; S Phase; Staurosporine; Tumor Cells, Cultured

2001
2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine: a novel anticancer nucleoside analog that causes both DNA strand breaks and G(2) arrest.
    Molecular pharmacology, 2001, Volume: 59, Issue:4

    Topics: Antineoplastic Agents; CDC2 Protein Kinase; Chromosome Breakage; Cyclin B; Cyclin B1; Cytarabine; Deoxycytidine; DNA, Neoplasm; G2 Phase; Gemcitabine; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Phosphorylation; RNA; Tumor Cells, Cultured

2001