Page last updated: 2024-08-24

gemcitabine and Acute Lymphoid Leukemia

gemcitabine has been researched along with Acute Lymphoid Leukemia in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (28.57)18.2507
2000's5 (35.71)29.6817
2010's3 (21.43)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Arentsen-Peters, STCJM; Castro, PG; Cheung, LC; Chua, GA; Dolman, MEM; Jones, L; Kerstjens, M; Koopmans, B; Kotecha, RS; Molenaar, JJ; Pieters, R; Pinhan̉«os, SS; Schneider, P; Singh, S; Stam, RW; Wander, P; Zwaan, CM1
Ebadi, M; Gordon, DJ; Gordon, PM; Jonart, LM; Koppenhafer, SL; Ostergaard, J1
Alexander, PM; Caudell, DL; Kucera, GL; Pardee, TS; Pladna, KM1
Aleksandrova, LN; Bezborodova, OA; Iakubovskaia, RI; Kovalenko, AL; Nemtsova, ER; Venediktova, IuB1
Borders, EB; Cherry, MA; Herman, T; Holter, J; Selby, GB; Srour, SA1
Amberger, A; Gnaiger, E; Kofler, R; Konwalinka, G; Renner, K1
Angiolillo, AL; Chen, Z; Krailo, M; Reaman, G; Whitlock, J1
Hudson, MM1
Boos, J; Henze, G; von Stackelberg, A; Wagner-Bohn, A1
Arkenau, HT; Ethell, M; Hiwarkar, P; Morgan, G; Potter, M; Treleaven, J1
Boeck, G; Egle, A; Geisen, F; Greil, R; Gruber, J; Konwalinka, G; Sgonc, R; Villunger, A1
Chitambar, CR; Elford, HL; Myette, MS1
Chubb, S; Grindey, GB; Heinemann, V; Hertel, LW; Plunkett, W; Sen, A; Xu, YZ1
Gandhi, V; Heinemann, V; Huang, P; Plunkett, W; Xu, YZ1

Trials

2 trial(s) available for gemcitabine and Acute Lymphoid Leukemia

ArticleYear
Phase II study of gemcitabine in children with relapsed acute lymphoblastic leukemia or acute myelogenous leukemia (ADVL0022): a Children's Oncology Group Report.
    Pediatric blood & cancer, 2006, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Child; Child, Preschool; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Humans; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Failure

2006
Phase II study of gemcitabine in children with relapsed leukemia.
    Pediatric blood & cancer, 2006, Volume: 46, Issue:2

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Deoxycytidine; Female; Gemcitabine; Humans; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence

2006

Other Studies

12 other study(ies) available for gemcitabine and Acute Lymphoid Leukemia

ArticleYear
Preclinical efficacy of gemcitabine in MLL-rearranged infant acute lymphoblastic leukemia.
    Leukemia, 2020, Volume: 34, Issue:11

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Disease Management; Disease Models, Animal; Drug Evaluation, Preclinical; Gemcitabine; Gene Rearrangement; Genetic Predisposition to Disease; Humans; Infant; Myeloid-Lymphoid Leukemia Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma

2020
Preclinical efficacy of prexasertib in acute lymphoblastic leukemia.
    British journal of haematology, 2021, Volume: 194, Issue:6

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Pyrazines; Pyrazoles

2021
The novel phospholipid mimetic KPC34 is highly active against preclinical models of Philadelphia chromosome positive acute lymphoblastic leukemia.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cytarabine; Deoxycytidine; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gemcitabine; Glycerophosphates; Humans; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Transplantation; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase C; Random Allocation; Tumor Burden

2017
[Experimental study of remaxol as a drug for supportive therapy in traditional and high-dose treatment of tumors].
    Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Deoxycytidine; Etoposide; Gemcitabine; Methotrexate; Mice; Neoplasms, Experimental; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Succinates

2013
Role of topotecan, vinorelbine, thiotepa and gemcitabine chemotherapy in relapsed/refractory adult acute leukemia.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retreatment; Thiotepa; Topotecan; Treatment Outcome; Vinblastine; Vinorelbine

2015
Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells.
    Biochimica et biophysica acta, 2003, Sep-23, Volume: 1642, Issue:1-2

    Topics: Apoptosis; Cell Respiration; Cell Size; Cell Survival; Cytosol; Deoxycytidine; Dexamethasone; Electron Transport; G1 Phase; Gemcitabine; Genes, cdc; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-bcl-2; S Phase; Tumor Cells, Cultured

2003
Achieving cure for early stage pediatric Hodgkin disease with minimal morbidity: are we there yet?
    Pediatric blood & cancer, 2006, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Child; Child, Preschool; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Humans; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Failure

2006
The feasibility of using topotecan, vinorelbine, thiotepa and gemcitabine (TVTG) in adult patients with relapsed/refractory acute lymphoblastic leukaemia/lymphoma.
    Leukemia, 2008, Volume: 22, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Feasibility Studies; Female; Gemcitabine; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retrospective Studies; Thiotepa; Topotecan; Vinblastine; Vinorelbine

2008
2',2'-Difluorodeoxycytidine (gemcitabine) induces apoptosis in myeloma cell lines resistant to steroids and 2-chlorodeoxyadenosine (2-CdA).
    Stem cells (Dayton, Ohio), 1996, Volume: 14, Issue:3

    Topics: 2-Chloroadenosine; Antimetabolites, Antineoplastic; Apoptosis; Biotin; Deoxyadenosines; Deoxycytidine; Deoxyuracil Nucleotides; Dexamethasone; DNA Damage; Drug Resistance; Gemcitabine; Glucocorticoids; Hematopoietic Stem Cells; Humans; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sensitivity and Specificity; Staining and Labeling; Steroids; Tumor Cells, Cultured

1996
Interaction of gallium nitrate with other inhibitors of ribonucleotide reductase: effects on the proliferation of human leukemic cells.
    Cancer letters, 1998, Jul-17, Volume: 129, Issue:2

    Topics: Antineoplastic Agents; Benzamidines; Cell Division; Deoxycytidine; Drug Synergism; Enzyme Inhibitors; Gallium; Gemcitabine; Humans; Hydroxamic Acids; Hydroxyurea; Oximes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Ribonucleotide Reductases; Tumor Cells, Cultured

1998
Cellular elimination of 2',2'-difluorodeoxycytidine 5'-triphosphate: a mechanism of self-potentiation.
    Cancer research, 1992, Feb-01, Volume: 52, Issue:3

    Topics: Antimetabolites, Antineoplastic; Cell Line; Cytidine Triphosphate; DCMP Deaminase; Deoxycytidine; Deoxyribonucleotides; Gemcitabine; Humans; Kinetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Ribonucleotides

1992
Metabolism and action of 2',2'-difluorodeoxycytidine: self-potentiation of cytotoxicity.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Arabinofuranosylcytosine Triphosphate; Base Sequence; Cell Line; Cell Survival; DCMP Deaminase; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyribonucleotides; DNA Polymerase II; Gemcitabine; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Sequence Data; Oligodeoxyribonucleotides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Stem Cell Assay

1991