Page last updated: 2024-09-03

gefitinib and Mesothelioma

gefitinib has been researched along with Mesothelioma in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ikeda, S; Suzuki, K; Takabe, K1
Bajetto, A; Barbieri, F; Corte, G; Favoni, RE; Florio, T; Gatti, M; Gaudino, G; Lo Casto, M; Mutti, L; Paleari, L; Pattarozzi, A; Porcile, C1
Baldi, A; Canino, C; Cardillo, I; Galati, R; Sacchi, A; Stoppoloni, D; Verdina, A1
Bellini, P; Favoni, RE; Harvey, BJ; Manente, AG; Moro, L; Mutti, L; Pinton, G; Thomas, W1
Bueno, R; Corson, JM; Fletcher, JA; Flynn, DL; Hubert, C; Ou, WB; Sugarbaker, DJ1
Dhalluin, X; Scherpereel, A1
Jänne, PA; Johnson, BE; Salgia, R; Taffaro, ML1
Govindan, R; Green, MR; Herndon, JE; Kindler, HL; Kratzke, RA; Niehans, GA; Vollmer, R; Watson, D1
Cortese, JF; Eliason, JF; Everson, RB; Gowda, AL; Pass, HI; Wali, A1
Goto, H; Hanibuchi, M; Ikuta, K; Kakiuchi, S; Nakataki, E; Nishioka, Y; Ogino, H; Ryan, A; Sone, S; Yamada, T; Yano, S1

Reviews

1 review(s) available for gefitinib and Mesothelioma

ArticleYear
Chemotherapy and radiotherapy for mesothelioma.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2011, Volume: 189

    Topics: Antineoplastic Agents; Asbestos; Combined Modality Therapy; Gefitinib; Genetic Therapy; Histone Deacetylase Inhibitors; Humans; Immunologic Factors; Mesothelioma; Pleural Neoplasms; Quinazolines; Ribonucleases; Thalidomide

2011

Trials

1 trial(s) available for gefitinib and Mesothelioma

ArticleYear
Gefitinib in patients with malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Mar-15, Volume: 11, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Disease Progression; Drug Administration Schedule; ErbB Receptors; Female; Gefitinib; Humans; Male; Mesothelioma; Middle Aged; Peritoneal Neoplasms; Pleural Neoplasms; Prognosis; Quinazolines; Survival Rate; Treatment Outcome

2005

Other Studies

8 other study(ies) available for gefitinib and Mesothelioma

ArticleYear
[Epidermal growth factor receptor aberrations in malignant mesotheliomas].
    Rinsho byori. The Japanese journal of clinical pathology, 2009, Volume: 57, Issue:7

    Topics: Antineoplastic Agents; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Mesothelioma; Quinazolines

2009
Gefitinib targets EGFR dimerization and ERK1/2 phosphorylation to inhibit pleural mesothelioma cell proliferation.
    Current cancer drug targets, 2010, Volume: 10, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Cross-Linking Reagents; ErbB Receptors; Fluorescent Antibody Technique; Gefitinib; Humans; Mesothelioma; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Pleural Neoplasms; Protein Multimerization; Quinazolines; Tumor Cells, Cultured

2010
Synergistic effect of gefitinib and rofecoxib in mesothelioma cells.
    Molecular cancer, 2010, Feb-02, Volume: 9

    Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclooxygenase 2; Drug Synergism; ErbB Receptors; Gefitinib; Humans; Lactones; Mesothelioma; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; Sulfones

2010
Estrogen receptor β exerts tumor repressive functions in human malignant pleural mesothelioma via EGFR inactivation and affects response to gefitinib.
    PloS one, 2010, Nov-29, Volume: 5, Issue:11

    Topics: Blotting, Western; Caveolin 1; Cell Line, Tumor; Cell Proliferation; Epidermal Growth Factor; ErbB Receptors; Estrogen Receptor beta; Gefitinib; Humans; Immunoprecipitation; Mesothelioma; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Pleural Neoplasms; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; RNA Interference

2010
Targeted inhibition of multiple receptor tyrosine kinases in mesothelioma.
    Neoplasia (New York, N.Y.), 2011, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Axl Receptor Tyrosine Kinase; Benzoquinones; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Interactions; Enzyme Activation; ErbB Receptors; Gefitinib; HSP90 Heat-Shock Proteins; Humans; Indoles; Lactams, Macrocyclic; Mesothelioma; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Quinazolines; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Sulfones

2011
Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma.
    Cancer research, 2002, Sep-15, Volume: 62, Issue:18

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Division; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Mesothelioma; Phosphorylation; Pleural Neoplasms; Quinazolines; Signal Transduction; Tumor Cells, Cultured

2002
Common EGFR mutations conferring sensitivity to gefitinib in lung adenocarcinoma are not prevalent in human malignant mesothelioma.
    International journal of cancer, 2006, Jan-15, Volume: 118, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; DNA Mutational Analysis; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Genetic Testing; Humans; Lung Neoplasms; Mesothelioma; Point Mutation; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Quinazolines

2006
Novel dual targeting strategy with vandetanib induces tumor cell apoptosis and inhibits angiogenesis in malignant pleural mesothelioma cells expressing RET oncogenic rearrangement.
    Cancer letters, 2008, Jun-28, Volume: 265, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Base Sequence; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Gefitinib; Gene Rearrangement; Humans; Male; Mesothelioma; Mice; Mice, SCID; Molecular Sequence Data; Neoplasm Transplantation; Neovascularization, Pathologic; Piperidines; Pleural Neoplasms; Proto-Oncogene Proteins c-ret; Quinazolines; Transplantation, Heterologous; Vascular Endothelial Growth Factor Receptor-2

2008