Page last updated: 2024-09-03

gefitinib and Cardiotoxicity

gefitinib has been researched along with Cardiotoxicity in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Agouni, A; Akhtar, S; Alanazi, FE; Aldhfyan, A; Alhoshani, A; Alotaibi, MR; Attwa, MW; Hourani, S; Kadi, AA; Korashy, HM; Zeidan, A1
Ahmad, SF; Al-Alallah, IA; Alhaider, AA; Anazi, FE; Ansari, MA; Assiri, MA; Attafi, IM; Belali, OM; Korashy, HM1

Other Studies

2 other study(ies) available for gefitinib and Cardiotoxicity

ArticleYear
EGFR Inhibitor Gefitinib Induces Cardiotoxicity through the Modulation of Cardiac PTEN/Akt/FoxO3a Pathway and Reactive Metabolites Formation:
    Chemical research in toxicology, 2020, 07-20, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cardiotoxicity; Cell Line; ErbB Receptors; Forkhead Box Protein O3; Gefitinib; Male; Membrane Potential, Mitochondrial; Microsomes; Myocardium; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats, Sprague-Dawley; Signal Transduction

2020
Molecular mechanisms of cardiotoxicity of gefitinib in vivo and in vitro rat cardiomyocyte: Role of apoptosis and oxidative stress.
    Toxicology letters, 2016, Jun-11, Volume: 252

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cardiomegaly; Cardiotoxicity; Caspase 3; Cell Line; Dose-Response Relationship, Drug; Gefitinib; Gene Expression Regulation; Heme Oxygenase (Decyclizing); Male; Myocytes, Cardiac; Oxidative Stress; Protein Kinase Inhibitors; Quinazolines; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53

2016