Page last updated: 2024-09-03

gefitinib and Bone Neoplasms

gefitinib has been researched along with Bone Neoplasms in 48 studies

Research

Studies (48)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	26 (54.17)	29.6817
2010's	16 (33.33)	24.3611
2020's	6 (12.50)	2.80

Authors

Authors	Studies
Harada, H; Katagiri, H; Miyagi, M; Mori, K; Murakami, H; Murata, H; Takahashi, M; Takahashi, T; Wasa, J	1
Blank, B; Kallis, MP; Maloney, C; Soffer, SZ; Steinberg, BM; Symons, M	1
Edelman, M; Kallis, MP; Lesser, M; Maloney, C; Soffer, SZ; Steinberg, BM; Symons, M; Tzanavaris, C	1
Fukuda, K; Kodama, K; Nanjyo, H; Shibata, H; Shimazu, K; Taguchi, D; Takahashi, S; Takahashi, T; Yoshida, T	1
Gong, YL; Hou, WT; Kang, JB; Lu, Y; Luo, F; Luo, Y; Qu, BL; Wang, F; Wu, DB; Xie, XQ; Yi, C	1
Mi, J; Xu, Q; Zhang, Y	1
Chen, PC; Chu, CY; Shih, YH	1
Li, YQ; Sun, H; Xue, D	1
Baresic, T; Basso, SM; Del Conte, A; Lumachi, F; Minatel, E; Schinella, D	1
Hida, T; Horio, Y; Kondo, C; Park, J; Shimizu, J; Yoshida, K	1
Iwase, T; Kishimoto, Y; Mori, H; Yano, T	1
Berger, W; Kubista, B; Lötsch, D; Mayr, L; Micksche, M; Pirker, C; Sevelda, F; van Schoonhoven, S; Windhager, R	1
Cai, XH; Feng, CJ; Huang, CY; Liu, XK; Lu, Y; Wang, L; Wang, Y; Wang, YS; Xu, Y; Yao, WX; Yu, P; Zhou, J; Zhu, WJ	1
Chen, Z; Wu, JH; Zhang, X; Zhao, J	1
Bashir, ES; Chan, CY; Kwan, AK; Mun Keong, K	1
Battaglia, M; Boccardo, F; Conti, G; Cruciani, G; Lapini, A; Manganelli, A; Ricci, S; Rubagotti, A	1
Kjellén, E; Lindén, O; Stenberg, L	1
Fujimoto, T; Ito, T; Kanda, S; Mori, S	1
Guan, ZZ; Huang, H; Wang, ZQ; Xu, F; Xu, GC; Zhang, L; Zhang, Y; Zhao, HY	1
Fleisher, M; Hu, G; Kang, Y; Lu, X; Massagué, J; Reiss, M; Van Poznak, C; Wang, Q	1
Ahn, JS; Ahn, MJ; Ahn, YC; Kim, JA; Lee, J; Lee, S; Park, HC; Park, K; Park, YH; Sun, JM	1
Chang, CC; Chang, HJ; Chi, KH; Hsieh, YS; Hsu, PS; Jiang, JS; Kao, SJ; Tsang, YW; Yeh, YW	1
Cui, CX; Hao, XZ; Li, JL; Shi, YK; Wang, B; Wang, HY; Wang, Y; Zhang, XR; Zhao, LD	1
Berglund, C; Chernoguz, A; Crawford, K; Cripe, TP; Donovan, E; Frischer, JS; Vandersall, A	1
Endo, M; Harada, H; Inomata, M; Kenmotsu, H; Murakami, H; Naito, T; Nakamura, Y; Ono, A; Shukuya, T; Takahashi, T; Tsuya, A; Yamamoto, N	1
Fujita, S; Hata, A; Imai, Y; Kaji, R; Katakami, N; Kida, Y; Tanaka, K	1
Hashisako, M; Ikegame, S; Kajiki, A; Kumazoe, H; Nagata, N; Wakamatsu, K	1
Hasegawa, S; Ishibashi, O; Kambayashi, T; Tanaka, F; Wada, H; Yanagihara, K	1
Cheshire, PJ; Daw, N; Germain, GS; Gilbertson, R; Harwood, FC; Houghton, PJ; Jenkins, JJ; Leggas, M; Panetta, JC; Peterson, J; Schuetz, JD; Stewart, CF	1
Bando, M; Hosono, T; Nakazawa, S; Ohno, S; Oshikawa, K; Sohara, Y; Sugiyama, Y	1
Albanell, J; Baselga, J; Gascón, P; González, S; Guillém, V; Koehler, MT; Lluch, A; Marimón, I; Rojo, F; Ruiz, A; Sauleda, S; Tabernero, JM	1
Aldinucci, D; D'Antonio, A; De Filippi, R; De Luca, A; Maiello, MR; Mancino, M; Normanno, N; Pinto, A	1
Hiddemann, W; Krych, M; Ostermann, H; Schoenberg, SO; Stemmler, HJ; Weigert, O	1
Berdel, WE; Hoffknecht, P; Lange, T; Müller-Tidow, C; Serve, H; Thomas, M	1
Choong, NW; Davies, GC; Dietrich, S; Husain, AN; Lipkowitz, S; Ma, PC; Nallasura, V; Salgia, R; Seiwert, TY; Tretiakova, MS	1
Gullick, WJ; Normanno, N	1
Angelucci, A; Bologna, M; Festuccia, C; Gravina, GL; Millimaggi, D; Muzi, P; Rucci, N; Teti, A; Vicentini, C	1
Katakami, N	1
Arimura, K; Higashimoto, I; Machida, K; Matsuyama, W; Mitsuyama, H; Osame, M; Watanabe, M; Yamamoto, M	1
An, TT; Fang, J; Liu, XY; Wu, MN; Yang, L	1
Akie, K; Asahina, H; Dosaka-Akita, H; Harada, M; Ishida, T; Isobe, H; Kinoshita, I; Konishi, J; Munakata, M; Nishimura, M; Ogura, S; Sukoh, N; Yamazaki, K; Yokouchi, H	1
Garfield, D	1
Chen, XQ; Rong, TH; Wei, WD; Wen, ZS; Wu, HY	1
Bell, DW; Brannigan, BW; Morabito, A; Moscato, M; Normanno, N; Zampa, G	1
Arai, Y; Kojima, A	1
Hida, T; Mitsudomi, T; Sugiura, H; Sugiura, T; Yamada, K	1
Nishio, M; Okano, Y	1
Li, AW; Xu, JF; Zhou, CC	1

Reviews

2 review(s) available for gefitinib and Bone Neoplasms

Article	Year
A severe dermatologic adverse effect related with gefitinib: case report and review of the literature. Journal of cancer research and therapeutics, 2013, Volume: 9 Suppl 2 Topics: Antineoplastic Agents; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Edema; Erythema; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Quinazolines	2013
[Efficacy of gefitinib in treatment of lung cancer patients with bone metastasis]. Clinical calcium, 2008, Volume: 18, Issue:4 Topics: Alkaline Phosphatase; Antineoplastic Agents; Biomarkers; Bone Neoplasms; Bone Resorption; Collagen Type I; Female; Fractures, Spontaneous; Gefitinib; Humans; Lung Neoplasms; Middle Aged; Osteogenesis; Peptide Fragments; Peptides; Procollagen; Quinazolines	2008

Trials

5 trial(s) available for gefitinib and Bone Neoplasms

Article	Year
Prednisone plus gefitinib versus prednisone plus placebo in the treatment of hormone-refractory prostate cancer: a randomized phase II trial. Oncology, 2008, Volume: 74, Issue:3-4 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Double-Blind Method; Gefitinib; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasms, Hormone-Dependent; Placebos; Prednisone; Prognosis; Prostatic Neoplasms; Quinazolines; Survival Rate; Treatment Outcome	2008
Upfront gefitinib/erlotinib treatment followed by concomitant radiotherapy for advanced lung cancer: a mono-institutional experience. Lung cancer (Amsterdam, Netherlands), 2011, Volume: 73, Issue:2 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Disease-Free Survival; Erlotinib Hydrochloride; Female; Gefitinib; Heart Neoplasms; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Pleural Neoplasms; Protein Kinase Inhibitors; Quinazolines; Treatment Outcome	2011
Phase II and tumor pharmacodynamic study of gefitinib in patients with advanced breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-10, Volume: 23, Issue:23 Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Bone Neoplasms; Breast Neoplasms; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p27; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gefitinib; Humans; Ki-67 Antigen; Male; Maximum Tolerated Dose; Middle Aged; Mitogen-Activated Protein Kinases; Phosphorylation; Quinazolines; Salvage Therapy; Soft Tissue Neoplasms; Treatment Outcome; Tumor Suppressor Proteins	2005
[Efficacy of gefitinib on advanced non-small cell lung cancer of bilateral diffuse or unilateral giant mass type]. Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:4 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Diarrhea; Disease-Free Survival; Exanthema; Female; Follow-Up Studies; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pruritus; Quality of Life; Quinazolines; Remission Induction	2007
[Gefitinib in the treatment of refractory non-small cell lung cancer]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2007, Volume: 29, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Diarrhea; Disease-Free Survival; ErbB Receptors; Exanthema; Female; Follow-Up Studies; Gefitinib; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Quality of Life; Quinazolines; Remission Induction; Survival Rate	2007

Other Studies

41 other study(ies) available for gefitinib and Bone Neoplasms

Article	Year
Osteosclerotic change as a therapeutic response to gefitinib in symptomatic non-small cell lung cancer bone metastasis. BMC pulmonary medicine, 2022, Dec-29, Volume: 22, Issue:1 Topics: Antineoplastic Agents; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Lung Neoplasms; Mutation; Protein Kinase Inhibitors; Quinazolines	2022
Pharmacological prevention of surgery-accelerated metastasis in an animal model of osteosarcoma. Journal of translational medicine, 2020, 04-30, Volume: 18, Issue:1 Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Gefitinib; Lung Neoplasms; Mice; Neoplasm Metastasis; Osteosarcoma	2020
Gefitinib Inhibits Invasion and Metastasis of Osteosarcoma via Inhibition of Macrophage Receptor Interacting Serine-Threonine Kinase 2. Molecular cancer therapeutics, 2020, Volume: 19, Issue:6 Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Proliferation; Female; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, Nude; Neoplasm Invasiveness; Osteosarcoma; Receptor-Interacting Protein Serine-Threonine Kinase 2; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2020
Lung adenocarcinoma in a patient with Li-Fraumeni syndrome bearing a novel germ-line mutation, TP53R333Vfs12. Japanese journal of clinical oncology, 2020, Sep-28, Volume: 50, Issue:10* Topics: Acrylamides; Adenocarcinoma of Lung; Adult; Aniline Compounds; Bone Neoplasms; Female; Gefitinib; Germ-Line Mutation; Humans; Li-Fraumeni Syndrome; Lung Neoplasms; Male; Pedigree; Protein Kinase Inhibitors; Tumor Suppressor Protein p53	2020
Long-term survival case of a non-small cell lung cancer bone metastasis patient treated with bone cement, radiation and gefitinib. European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:6 Topics: Aged; Antineoplastic Agents; Bone Cements; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Female; Gefitinib; Humans; Lung Neoplasms	2021
Lung adenocarcinoma presents with diffuse bone metastasis. Thoracic cancer, 2021, Volume: 12, Issue:19 Topics: Adenocarcinoma of Lung; Antineoplastic Agents; Bone Density Conservation Agents; Bone Neoplasms; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Positron Emission Tomography Computed Tomography; Zoledronic Acid	2021
Severe refractory scarring alopecia associated with combinational use of ficlatuzumab (AV-299) and gefitinib. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jul-10, Volume: 31, Issue:20 Topics: Aged; Alopecia; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Cicatrix; Female; Follow-Up Studies; Gefitinib; Humans; Immunohistochemistry; Lung Neoplasms; Quinazolines; Risk Assessment; Severity of Illness Index	2013
Complete metabolic remission with Gefitinib in a hemodialysis patient with bone metastases from non-small cell lung cancer. Anticancer research, 2014, Volume: 34, Issue:1 Topics: Aged; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Feasibility Studies; Gefitinib; Humans; Kidney Failure, Chronic; Lung Neoplasms; Male; Positron-Emission Tomography; Prognosis; Quinazolines; Remission Induction; Renal Dialysis; Tomography, X-Ray Computed	2014
EGFR exon 19 insertions show good response to gefitinib, but short time to progression in Japanese patients. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2014, Volume: 9, Issue:2 Topics: Adenocarcinoma; Aged; Bone Neoplasms; ErbB Receptors; Exons; Female; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Protein Kinase Inhibitors; Quinazolines	2014
Reossification of osteolytic metastases at the acetabulum following gefitinib and multidisciplinary treatment for lung cancer: a case report with autopsy findings. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2015, Volume: 20, Issue:5 Topics: Acetabulum; Adenocarcinoma; Administration, Oral; Antineoplastic Agents; Autopsy; Biopsy; Bone Neoplasms; Disease Progression; ErbB Receptors; Fatal Outcome; Female; Follow-Up Studies; Gefitinib; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Middle Aged; Ossification, Heterotopic; Quinazolines; Tomography, X-Ray Computed	2015
EGFR is not a major driver for osteosarcoma cell growth in vitro but contributes to starvation and chemotherapy resistance. Journal of experimental & clinical cancer research : CR, 2015, Nov-02, Volume: 34 Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Gene Expression; Humans; Osteosarcoma; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction	2015
Bisphosphonates enhance EGFR-TKIs efficacy in advanced NSCLC patients with EGFR activating mutation: A retrospective study. Oncotarget, 2016, Oct-11, Volume: 7, Issue:41 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Crown Ethers; Diphosphonates; Disease-Free Survival; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Imidazoles; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Mutation; Pamidronate; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Treatment Outcome; Zoledronic Acid	2016
Case Report: Bazex Syndrome Associated With Pulmonary Adenocarcinoma. Medicine, 2016, Volume: 95, Issue:2 Topics: Acitretin; Adenocarcinoma; Adenocarcinoma of Lung; Aged, 80 and over; Biopsy, Needle; Bone Neoplasms; Carcinoma, Basal Cell; Dexamethasone; Drug Therapy, Combination; Follow-Up Studies; Gefitinib; Humans; Hypotrichosis; Immunohistochemistry; Lung Neoplasms; Lymph Nodes; Male; Paraneoplastic Syndromes; Quinazolines; Radiography; Rare Diseases; Risk Assessment; Skin Neoplasms; Treatment Outcome	2016
Remarkable bone formation following gefitinib for extensive lytic bone metastasis: a report of two cases. Journal of orthopaedic surgery (Hong Kong), 2016, Volume: 24, Issue:3 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged, 80 and over; Antineoplastic Agents; Bone Neoplasms; Female; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Osteogenesis; Pelvic Bones; Quinazolines; Spine	2016
Regression of cervical spinal cord compression in a patient with chordoma following treatment with cetuximab and gefitinib. Acta oncologica (Stockholm, Sweden), 2009, Volume: 48, Issue:1 Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cervical Vertebrae; Cetuximab; Chordoma; Female; Gefitinib; Humans; Middle Aged; Quinazolines; Spinal Cord Compression	2009
[Potent and continuous relief of spinal bone pain due to metastasis of non-small cell lung cancer by treatment with gefitinib--a case report]. Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:5 Topics: Aged; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Fatal Outcome; Female; Gefitinib; Humans; Lung Neoplasms; Pain; Quinazolines; Spine; Tomography, X-Ray Computed	2009
[Analysis of the efficacy and safety of gefitinib in the treatment of recurrent advanced non-small cell lung cancer in an expanded access program (EAP)]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2009, Volume: 31, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Diarrhea; Exanthema; Female; Follow-Up Studies; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Proportional Hazards Models; Quinazolines; Remission Induction; Survival Rate; Young Adult	2009
ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. Genes & development, 2009, Aug-15, Volume: 23, Issue:16 Topics: ADAM Proteins; ADAMTS1 Protein; Animals; Bone and Bones; Bone Neoplasms; Breast Neoplasms; Cell Differentiation; Cell Line; Cell Proliferation; Epidermal Growth Factor; Female; Gefitinib; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Silencing; Matrix Metalloproteinase 1; Mice; Mice, Nude; Osteoblasts; Osteoprotegerin; Protein Kinase Inhibitors; Quinazolines; RANK Ligand; Signal Transduction	2009
Predictors of skeletal-related events in non-small cell lung cancer patients with bone metastases. Lung cancer (Amsterdam, Netherlands), 2011, Volume: 71, Issue:1 Topics: Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Diphosphonates; ErbB Receptors; Erlotinib Hydrochloride; Female; Follow-Up Studies; Gefitinib; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies	2011
[Factors affecting the sensitivity of EGFR-TKI treatment in advanced non-small cell lung cancer]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011, Volume: 33, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Carcinoembryonic Antigen; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; ErbB Receptors; Erlotinib Hydrochloride; Female; Follow-Up Studies; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Smoking	2011
EGFR inhibition fails to suppress vascular proliferation and tumor growth in a Ewing's sarcoma model. The Journal of surgical research, 2012, Volume: 173, Issue:1 Topics: Angiography; Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; ErbB Receptors; Female; Gefitinib; Humans; In Vitro Techniques; Mice; Mice, Nude; Neovascularization, Pathologic; Quinazolines; Sarcoma, Ewing; Transplantation, Heterologous; Vascular Endothelial Growth Factor A	2012
Continuous administration of EGFR-TKIs following radiotherapy after disease progression in bone lesions for non-small cell lung cancer. Anticancer research, 2011, Volume: 31, Issue:12 Topics: Adult; Aged; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free Survival; Enzyme Inhibitors; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Quinazolines; Receptor Protein-Tyrosine Kinases; Retrospective Studies; Treatment Outcome	2011
Gefitinib for a poor performance status patient with squamous cell carcinoma of the lung harboring EGFR mutation. Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:6 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Docetaxel; ErbB Receptors; Fatal Outcome; Gefitinib; Genes, erbB-1; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Proteins; Palliative Care; Protein Kinase Inhibitors; Quinazolines; Severity of Illness Index; Smoking; Taxoids; Tomography, X-Ray Computed	2012
Flare phenomenon following gefitinib treatment of lung adenocarcinoma with bone metastasis. The Tohoku journal of experimental medicine, 2012, Volume: 228, Issue:2 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Alkaline Phosphatase; Antineoplastic Agents; Bone and Bones; Bone Neoplasms; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Polyphosphates; Quinazolines; Radionuclide Imaging; Technetium Compounds; Tomography, X-Ray Computed; Treatment Outcome	2012
[Advanced lung cancer of performance status 3 successfully treated by gefitinib--a case report]. Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:2 Topics: Administration, Oral; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Drug Administration Schedule; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pain, Intractable; Quality of Life; Quinazolines	2004
Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice. Cancer research, 2004, Oct-15, Volume: 64, Issue:20 Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Bone Neoplasms; Camptothecin; Cell Line, Tumor; Drug Synergism; ErbB Receptors; Female; Gefitinib; Humans; Irinotecan; Mice; Mice, Inbred ICR; Mice, SCID; Neoplasm Proteins; Osteosarcoma; Quinazolines; Xenograft Model Antitumor Assays	2004
[Two cases of lung cancer in the third decade of life]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2004, Volume: 42, Issue:9 Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Female; Gefitinib; Humans; Lung Neoplasms; Male; Quinazolines; Radiography, Thoracic; Tomography, X-Ray Computed	2004
Gefitinib inhibits the ability of human bone marrow stromal cells to induce osteoclast differentiation: implications for the pathogenesis and treatment of bone metastasis. Endocrine-related cancer, 2005, Volume: 12, Issue:2 Topics: Antineoplastic Agents; Bone Marrow Cells; Bone Neoplasms; Cell Differentiation; ErbB Receptors; Gefitinib; Humans; Osteoclasts; Quinazolines; Stromal Cells	2005
Brain metastases in metastatic non-small cell lung cancer responding to single-agent gefitinib: a case report. Anti-cancer drugs, 2005, Volume: 16, Issue:7 Topics: Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Female; Gefitinib; Humans; Lung Neoplasms; Middle Aged; Quinazolines	2005
First-line systemic treatment with gefitinib in stage IV non-small cell lung cancer. Oncology reports, 2005, Volume: 14, Issue:6 Topics: Adenocarcinoma; Antineoplastic Agents; Base Sequence; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; DNA Mutational Analysis; ErbB Receptors; Female; Gefitinib; Humans; Lung Neoplasms; Middle Aged; Neoplasm Staging; Quinazolines; Sequence Deletion; Treatment Outcome	2005
Gefitinib response of erlotinib-refractory lung cancer involving meninges--role of EGFR mutation. Nature clinical practice. Oncology, 2006, Volume: 3, Issue:1 Topics: Adenocarcinoma; Aged; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Meningeal Neoplasms; Mutation; Quinazolines; Ribs; Treatment Failure	2006
Epidermal growth factor receptor tyrosine kinase inhibitors and bone metastases: different mechanisms of action for a novel therapeutic application? Endocrine-related cancer, 2006, Volume: 13, Issue:1 Topics: Antineoplastic Agents; Bone Neoplasms; ErbB Receptors; Gefitinib; Humans; Male; Prostatic Neoplasms; Quinazolines; Signal Transduction	2006
Suppression of EGF-R signaling reduces the incidence of prostate cancer metastasis in nude mice. Endocrine-related cancer, 2006, Volume: 13, Issue:1 Topics: Animals; Antineoplastic Agents; Blotting, Western; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Culture Media, Conditioned; ErbB Receptors; Gefitinib; Humans; Immunoprecipitation; Incidence; Male; Matrix Metalloproteinase 9; Mice; Mice, Nude; Prostatic Neoplasms; Quinazolines; Signal Transduction; Stromal Cells; Xenograft Model Antitumor Assays	2006
[Lung cancer with bone metastasis]. Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:8 Topics: Analgesics; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Diphosphonates; Docetaxel; Drug Administration Schedule; Etoposide; Fractures, Bone; Gefitinib; Humans; Irinotecan; Lung Neoplasms; Paclitaxel; Pain, Intractable; Prognosis; Quinazolines; Radiotherapy Dosage; Taxoids	2006
[Two lung adenocarcinoma patients with multiple brain metastasis treated with Gefitinib and surviving more than 2 years]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2006, Volume: 44, Issue:9 Topics: Adenocarcinoma, Papillary; Aged; Aged, 80 and over; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Drug Administration Schedule; Female; Gefitinib; Humans; Lung Neoplasms; Quinazolines; Radiotherapy Dosage; Survivors	2006
[Gefitinib in the treatment of advanced non-small cell lung cancer]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2006, Volume: 28, Issue:6 Topics: Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Disease Progression; Exanthema; Female; Follow-Up Studies; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Quinazolines; Survival Analysis; Treatment Outcome	2006
Clinical benefit of readministration of gefitinib for initial gefitinib-responders with non-small cell lung cancer. BMC cancer, 2007, Mar-20, Volume: 7 Topics: Administration, Oral; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Combined Modality Therapy; Drug Administration Schedule; Female; Follow-Up Studies; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Male; Quinazolines; Retrospective Studies; Treatment Outcome	2007
Increasing osteoblastic lesions as a manifestation of a major response to gefitinib. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2006, Volume: 1, Issue:8 Topics: Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Female; Gefitinib; Humans; Lung Neoplasms; Middle Aged; Protein Kinase Inhibitors; Quinazolines	2006
Prolonged control of bone metastases in non-small-cell lung cancer patients treated with gefitinib. Lung cancer (Amsterdam, Netherlands), 2008, Volume: 60, Issue:3 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Drug Resistance, Neoplasm; ErbB Receptors; Follow-Up Studies; Gefitinib; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Neoplasm Recurrence, Local; Quinazolines; Time Factors	2008
[A case of lung cancer with alkaline phosphatase flare phenomenon during gefitinib therapy]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2007, Volume: 45, Issue:12 Topics: Adenocarcinoma; Aged; Alkaline Phosphatase; Antineoplastic Agents; Bone Neoplasms; Female; Gefitinib; Humans; Lung Neoplasms; Quinazolines	2007
Predictors of survival in patients with bone metastasis of lung cancer. Clinical orthopaedics and related research, 2008, Volume: 466, Issue:3 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bone Neoplasms; ErbB Receptors; Female; Gefitinib; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prognosis; Proportional Hazards Models; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Sex Factors; Time Factors; Treatment Outcome	2008