Page last updated: 2024-09-03

gefitinib and Benign Meningeal Neoplasms

gefitinib has been researched along with Benign Meningeal Neoplasms in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (50.00)29.6817
2010's11 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, W; Li, Y; Luo, W; Song, J; Tian, P; Zhang, R; Zhou, Y1
Han, JY; Kim, HT; Kim, HY; Lee, GK; Lee, JS; Lee, Y; Yun, T1
Cioffredi, LA; Jackman, DM; Jacobs, L; Johnson, BE; Kesari, S; Lucca, J; Lynch, TJ; Marcoux, PJ; Morse, LK; Plotkin, SR; Rabin, MS; Sharmeen, F1
Iwakami, S; Katsura, Y; Kido, K; Ko, R; Namba, Y; Sasaki, S; Shukuya, T; Takahashi, K; Tominaga, S; Yoshioka, Y1
Chamberlain, MC; Le Rhun, E; Taillibert, S1
Chen, M; Gu, Y; Sun, Y; Wang, M; Xu, Y; Yang, Z; Ye, X; Zhao, J; Zhong, W; Zhu, G1
Bang, YJ; Han, SW; Heo, DS; Im, SA; Kim, CS; Kim, DW; Kim, HJ; Kim, TY; Kim, YJ; Lee, SH; Oh, DY; Yi, HG1
Abrey, LE; Aldape, K; Chang, SM; Cloughesy, TF; Dancey, J; Deangelis, LM; Fine, HA; Gilbert, MR; Lamborn, KR; Lassman, AB; Lieberman, F; Mehta, M; Norden, AD; Prados, MD; Raizer, JJ; Robins, HI; Wen, PY; Yung, WK1
Hisamoto, A; Kashihara, H; Kiura, K; Kubo, T; Nishida, A; Ochi, N; Takigawa, N; Tanimoto, M; Umemura, S1
Fukui, T; Hatooka, S; Hida, T; Ito, S; Katayama, T; Mitsudomi, T; Onozato, R; Shimizu, J; Suda, K; Sueda, T; Yatabe, Y1
Iwakawa, J; Kawamata, Y; Kumamoto, T; Suetsugu, T; Tanoue, A1
Nishizawa, S; Saito, T; Soejima, Y; Takahashi, M; Yamamoto, J1
Goya, S; Hirata, H; Kawase, I; Kida, H; Kijima, T; Kuhara, H; Minami, T; Nagatomo, I; Osa, A; Tachibana, I; Takahashi, R; Takeda, Y; Tetsumoto, S1
Fujiwara, K; Hamada, N; Horita, N; Hotta, K; Kamei, H; Kiura, K; Segawa, Y; Takata, I; Takigawa, N; Tanimoto, M; Tsubouchi, K; Umemura, S; Yamane, H; Yoshioka, H1
Fukudo, M; Ikemi, Y; Katsura, T; Kim, YH; Masago, K; Masuda, S; Mishima, M; Mizuno, T; Nagai, H; Sakamori, Y; Togashi, Y1
Abrey, LE; Franceschi, E; Kris, MG; Miller, VA; Milton, DT; Omuro, AM; Shah, N1
Choong, NW; Davies, GC; Dietrich, S; Husain, AN; Lipkowitz, S; Ma, PC; Nallasura, V; Salgia, R; Seiwert, TY; Tretiakova, MS1
Ishikawa, S; Ito, H; Onizuka, M; Ozawa, Y; Sakai, M; Sakakibara, Y; Yamamoto, T1
Bailey, C; Borras, AM; de Jong, F; Holmes, AJ; Jackman, DM; Jänne, PA; Johnson, BE; Kesari, S; Lindeman, N; Wen, PY1
Honmura, Y; Komagata, H; Kurimoto, F; Sakai, H; Sudo, J; Yoneda, S1
Abe, T; Haraguchi, M; Hayashi, M; Ito, K; Tsutsui, N1
Fukuhara, T; Inoue, A; Kanamori, M; Morikawa, N; Nakashima, I; Nukiwa, T; Saijo, Y; Sakakibara, T1

Reviews

1 review(s) available for gefitinib and Benign Meningeal Neoplasms

ArticleYear
Combined Use of Crizotinib and Gefitinib in Advanced Lung Adenocarcinoma With Leptomeningeal Metastases Harboring MET Amplification After the Development of Gefitinib Resistance: A Case Report and Literature Review.
    Clinical lung cancer, 2019, Volume: 20, Issue:3

    Topics: Adenocarcinoma of Lung; Antineoplastic Combined Chemotherapy Protocols; Circulating Tumor DNA; Crizotinib; Drug Resistance, Neoplasm; Female; Gefitinib; Gene Amplification; Humans; Lung Neoplasms; Meningeal Neoplasms; Middle Aged; Mutation; Neoplasm Staging; Proto-Oncogene Proteins c-met; Remission Induction

2019

Trials

4 trial(s) available for gefitinib and Benign Meningeal Neoplasms

ArticleYear
Impact of EGFR tyrosine kinase inhibitors versus chemotherapy on the development of leptomeningeal metastasis in never smokers with advanced adenocarcinoma of the lung.
    Journal of neuro-oncology, 2013, Volume: 115, Issue:1

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Disease Progression; ErbB Receptors; Female; Follow-Up Studies; Gefitinib; Gemcitabine; Humans; Lung Neoplasms; Male; Meningeal Neoplasms; Neoplasm Staging; Prognosis; Protein Kinase Inhibitors; Quinazolines; Survival Rate

2013
A phase I trial of high dose gefitinib for patients with leptomeningeal metastases from non-small cell lung cancer.
    Oncotarget, 2015, Feb-28, Volume: 6, Issue:6

    Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Gefitinib; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Meningeal Neoplasms; Middle Aged; Quinazolines

2015
Phase II trials of erlotinib or gefitinib in patients with recurrent meningioma.
    Journal of neuro-oncology, 2010, Volume: 96, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Erlotinib Hydrochloride; Female; Follow-Up Studies; Gefitinib; Humans; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Neoplasm Recurrence, Local; Protein Kinase Inhibitors; Quinazolines; Survival Analysis; Tomography, X-Ray Computed

2010
Cerebrospinal fluid concentration of gefitinib and erlotinib in patients with non-small cell lung cancer.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asian People; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Chromatography, High Pressure Liquid; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Japan; Lung Neoplasms; Male; Meningeal Neoplasms; Middle Aged; Mutation; Quinazolines; Tandem Mass Spectrometry; Treatment Outcome

2012

Other Studies

17 other study(ies) available for gefitinib and Benign Meningeal Neoplasms

ArticleYear
Diagnostic significance of cerebrospinal fluid EGFR mutation analysis for leptomeningeal metastasis in non-small-cell lung cancer patients harboring an active EGFR mutation following gefitinib therapy failure.
    Respiratory investigation, 2016, Volume: 54, Issue:1

    Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; DNA Mutational Analysis; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Lung Neoplasms; Male; Meningeal Neoplasms; Middle Aged; Mutation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Real-Time Polymerase Chain Reaction; Retrospective Studies; Time Factors; Treatment Failure; Treatment Outcome

2016
Systemic therapy for recurrent meningioma.
    Expert review of neurotherapeutics, 2016, Volume: 16, Issue:8

    Topics: Gefitinib; Humans; Kruppel-Like Factor 4; Meningeal Neoplasms; Meningioma; Prospective Studies; Quinazolines; Vascular Endothelial Growth Factor A

2016
EGFR mutation status of paired cerebrospinal fluid and plasma samples in EGFR mutant non-small cell lung cancer with leptomeningeal metastases.
    Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:6

    Topics: Adult; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Female; Gefitinib; Humans; Lung Neoplasms; Male; Meningeal Neoplasms; Middle Aged; Mutation; Quinazolines

2016
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are effective for leptomeningeal metastasis from non-small cell lung cancer patients with sensitive EGFR mutation or other predictive factors of good response for EGFR TKI.
    Lung cancer (Amsterdam, Netherlands), 2009, Volume: 65, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Lung Neoplasms; Male; Meningeal Neoplasms; Middle Aged; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Treatment Outcome

2009
Efficacy of a lumbo-peritoneal shunt for meningeal carcinomatosis refractory to gefitinib treatment.
    Anticancer research, 2009, Volume: 29, Issue:7

    Topics: Antineoplastic Agents; Cerebrospinal Fluid Shunts; Female; Gefitinib; Humans; Meningeal Neoplasms; Middle Aged; Quinazolines

2009
Efficacy of erlotinib for brain and leptomeningeal metastases in patients with lung adenocarcinoma who showed initial good response to gefitinib.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2009, Volume: 4, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; DNA, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Female; Follow-Up Studies; Gefitinib; Humans; Lung Neoplasms; Male; Meningeal Neoplasms; Middle Aged; Mutation; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Spinal Cord Neoplasms; Treatment Outcome

2009
[A case of meningeal carcinomatosis of lung adenocarcinoma well controlled by re-treatment with gefitinib].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:13

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Drug Resistance, Neoplasm; Female; Gefitinib; Genes, erbB-1; Humans; Lung Neoplasms; Meningeal Neoplasms; Mutation; Paclitaxel; Quinazolines

2009
Focal leptomeningeal metastasis following curative surgery for lung cancer: case report.
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Fatal Outcome; Female; Gefitinib; Humans; Lung Neoplasms; Meningeal Neoplasms; Middle Aged; Neoplasms, Multiple Primary; Quinazolines

2011
Two cases of leptomeningeal metastases from lung adenocarcinoma which progressed during gefitinib therapy but responded to erlotinib.
    International journal of clinical oncology, 2012, Volume: 17, Issue:2

    Topics: Blood-Brain Barrier; Carcinoma, Non-Small-Cell Lung; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Lung Neoplasms; Meningeal Neoplasms; Middle Aged; Quinazolines

2012
Clinical outcome in patients with leptomeningeal metastasis from non-small cell lung cancer: Okayama Lung Cancer Study Group.
    Lung cancer (Amsterdam, Netherlands), 2012, Volume: 77, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; DNA Mutational Analysis; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Meningeal Neoplasms; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Quinazolines; Retrospective Studies; Severity of Illness Index; Treatment Outcome

2012
High incidence of disease recurrence in the brain and leptomeninges in patients with nonsmall cell lung carcinoma after response to gefitinib.
    Cancer, 2005, Jun-01, Volume: 103, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cohort Studies; ErbB Receptors; Female; Gefitinib; Humans; Incidence; Lung Neoplasms; Male; Meningeal Neoplasms; Middle Aged; Neoplasm Staging; Quinazolines; Survival Rate; Treatment Failure

2005
Gefitinib response of erlotinib-refractory lung cancer involving meninges--role of EGFR mutation.
    Nature clinical practice. Oncology, 2006, Volume: 3, Issue:1

    Topics: Adenocarcinoma; Aged; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Meningeal Neoplasms; Mutation; Quinazolines; Ribs; Treatment Failure

2006
Carcinomatous meningitis from non-small-cell lung cancer responding to gefitinib.
    International journal of clinical oncology, 2006, Volume: 11, Issue:3

    Topics: Adult; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Gefitinib; Humans; Lung Neoplasms; Male; Meningeal Neoplasms; Meningitis; Quinazolines

2006
Response and resistance in a non-small-cell lung cancer patient with an epidermal growth factor receptor mutation and leptomeningeal metastases treated with high-dose gefitinib.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Sep-20, Volume: 24, Issue:27

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Male; Meningeal Neoplasms; Middle Aged; Mutation; Protein Kinase Inhibitors; Quinazolines; Treatment Outcome

2006
[Meningeal carcinomatosis in patients with lung cancer].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2006, Volume: 44, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Cerebrospinal Fluid; Combined Modality Therapy; Female; Gefitinib; Humans; Lung Neoplasms; Male; Meningeal Neoplasms; Middle Aged; Quality of Life; Quinazolines; Retrospective Studies; Survival Rate

2006
[Two cases of meningeal carcinomatosis during gefitinib therapy for non-small cell lung cancer].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2006, Volume: 44, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Disease Progression; Fatal Outcome; Female; Gefitinib; Humans; Lung Neoplasms; Male; Meningeal Neoplasms; Middle Aged; Quinazolines

2006
Successful treatment of carcinomatous meningitis with gefitinib in a patient with lung adenocarcinoma harboring a mutated EGF receptor gene.
    The Tohoku journal of experimental medicine, 2008, Volume: 214, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Combined Modality Therapy; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Male; Meningeal Neoplasms; Meningitis; Middle Aged; Mutation; Quinazolines; Radiotherapy

2008