gbr 12935 has been researched along with Substance Withdrawal Syndrome in 3 studies
1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine : An N-alkylpiperazine that consists of piperazine bearing 2-(benzhydryloxy)ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).
Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
| Excerpt | Relevance | Reference |
|---|
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kimmel, HL | 1 |
| Carroll, FI | 1 |
| Kuhar, MJ | 1 |
| Wilson, JM | 1 |
| Nobrega, JN | 1 |
| Carroll, ME | 1 |
| Niznik, HB | 1 |
| Shannak, K | 1 |
| Lac, ST | 1 |
| Pristupa, ZB | 1 |
| Dixon, LM | 1 |
| Kish, SJ | 1 |
| Hitri, A | 1 |
| Wyatt, RJ | 1 |
3 other studies available for gbr 12935 and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Withdrawal from repeated cocaine alters dopamine transporter protein turnover in the rat striatum.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine Plasma Membrane Transport Proteins; Half-Life; In Vitro | 2003 |
Heterogeneous subregional binding patterns of 3H-WIN 35,428 and 3H-GBR 12,935 are differentially regulated by chronic cocaine self-administration.
Topics: Animals; Biogenic Monoamines; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane T | 1994 |
Regional differences in rat brain dopamine transporter binding: function of time after chronic cocaine.
Topics: Animals; Brain; Brain Chemistry; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Prote | 1993 |